Systemic Lupus Erythematosus (Msq Drill 184)
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- 1.
Do connective tissue disorders usually isolate themselves to one organ or they usually involve multiple organs?
- A.
One organ
- B.
Multiple organs
Correct Answer
B. Multiple organs -
- 2.
The immune system basically attacks the body in connective tissue dieases. True or false?
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
Self directed immune mechanisms.Rate this question:
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- 3.
Which of the following diseases are examples of connective tissue diseases?
- A.
SLE & RA
- B.
Mixed connective tissue disease
- C.
Sjorgrens Syndrome & systemic sclerosis
- D.
Diabetes
- E.
Polymyositis/dermatomyositis
Correct Answer(s)
A. SLE & RA
B. Mixed connective tissue disease
C. Sjorgrens Syndrome & systemic sclerosis
E. Polymyositis/dermatomyositis -
- 4.
The basic problem in patients with CTD diseases is the presence of:
- A.
An elevated ESR
- B.
An elevated PSA
- C.
Metastasis
- D.
Antinuclear antobodies (ANA)
Correct Answer
D. Antinuclear antobodies (ANA) -
- 5.
What percentage of patients with SLE have ANAs?
- A.
50%
- B.
75%
- C.
99%
- D.
100%
Correct Answer
C. 99%Explanation
ANA's antinuclear antibodiesRate this question:
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- 6.
A patient cannot be diagnosed with a CTD in the absence od antinuclear antibodies. True or false?
- A.
True
- B.
False
Correct Answer
A. True -
- 7.
About _____ % of patients with antinuclear antibodies will NOT have a CTD?
- A.
2
- B.
3
- C.
5
- D.
15
- E.
25
Correct Answer
C. 5 -
- 8.
The prevalence of antinuclear antibodies in women is about 1 in every ______ women.
- A.
50
- B.
100
- C.
1000
- D.
10 000
Correct Answer
C. 1000 -
- 9.
So, if 1000 women are tested and 51 are ANA positive, about how many of these 51 women will have Systemic lupus erythmatosus?
- A.
1
- B.
5
- C.
15
- D.
25
Correct Answer
A. 1 -
- 10.
Which common symptoms are shared by most connective tissue diseases?
- A.
General systemis features such as malaise, fever or weight loss
- B.
Evidence of multiple organ system involvement
- C.
Musculoskeletal involvement-arthritis, myalgia
- D.
Immune alterations that leads to pathologic inflammation
Correct Answer(s)
A. General systemis features such as malaise, fever or weight loss
B. Evidence of multiple organ system involvement
C. Musculoskeletal involvement-arthritis, myalgia
D. Immune alterations that leads to pathologic inflammation -
- 11.
Systemic Lupus Erythmatosus is an autoimmune multisystem disease. True or false?
- A.
True
- B.
False
Correct Answer
A. True -
- 12.
In general SLE is more common in men or women?
- A.
Men
- B.
Women
Correct Answer
B. Women -
- 13.
What is the main cause of SLE?
- A.
Photosensitivity
- B.
Low folic acid
- C.
Immune complex deposition
Correct Answer
C. Immune complex deposition -
- 14.
What is the peak age of the onset for SLE?
- A.
15-25
- B.
5-15
- C.
18-36
- D.
30-55
Correct Answer
A. 15-25 -
- 15.
Which of the following are also presentations that can be seen in patients with SLE?
- A.
Photosensitive skin eruptions
- B.
Serositis
- C.
Pneumonitis
- D.
Myocarditis & nephritis
- E.
CNS involvement
Correct Answer(s)
A. pHotosensitive skin eruptions
B. Serositis
C. Pneumonitis
D. Myocarditis & nepHritis
E. CNS involvement -
- 16.
What is the most common presentation of SLE?a
- A.
Rhabdomyolisis
- B.
Skin eruptions
- C.
Seizures
Correct Answer
B. Skin eruptions -
- 17.
Do we know exactly what causes SLE?
- A.
Yes
- B.
No
Correct Answer
B. No -
- 18.
Are there triggers for SLE?
- A.
Yes. eg UV light and sulfa drugs
- B.
No, it is an autoimmune disease so there are no triggers.
Correct Answer
A. Yes. eg UV light and sulfa drugs -
- 19.
Drug induced Lupus can be caused by the following drugs:
- A.
Hydralazine
- B.
Loperamide
- C.
Procainamide
- D.
Hydrochlorothiazide
Correct Answer(s)
A. Hydralazine
C. Procainamide -
- 20.
UV light & sulfa driugs are definite, probable or possible cause of lupus?
- A.
Definite
- B.
Probable
- C.
Possible
Correct Answer
A. Definite -
- 21.
Can hair dyes and lipstick cause SLE?
- A.
Yes
- B.
No
Correct Answer
A. Yes -
- 22.
Anti-histone antibody is a sub serologic test goes along with:
- A.
Systemis lupus
- B.
Rheumatoid arthritis
- C.
Osteoporosis
- D.
Drug induced lupus
Correct Answer
D. Drug induced lupus -
- 23.
Is SLE more common in white or black populations?
- A.
White
- B.
Black
Correct Answer
A. White -
- 24.
The diagnois of SLE is a clnical diagnosis?
- A.
Yes
- B.
No
Correct Answer
A. Yes -
- 25.
There are 11 criteria for the diagnosis of SLE. In order to diagnose how many criteria out of the 11 do you have to have?
- A.
2
- B.
3
- C.
4
- D.
5
- E.
6
Correct Answer
C. 4 -
- 26.
The butterfly rash seen in SLE is kown as the ________ rash.
- A.
Malar
- B.
Atopic
- C.
Contact dermatitis
- D.
Lichen planus
Correct Answer
A. Malar -
- 27.
The malar rash of SLE spares which part?
- A.
Temporal area
- B.
Eyelids
- C.
Nasolabial folds
Correct Answer
C. Nasolabial folds -
- 28.
If a patient with lupus has raised patches, adherent keratotic scaline, perifollicular pugging and scarring from older lesions, you would document this as a:
- A.
Malar rash
- B.
Discoid rash
Correct Answer
B. Discoid rashExplanation
A malar rash is erythematic, flat or raised.Rate this question:
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- 29.
Can patients with SLE develop a skin rash after exposure to sunlight?
- A.
Yes
- B.
No
Correct Answer
A. Yes -
- 30.
SLE patients can also have oral or nasopharyngeal ulcers. Are these painful or painless?
- A.
Painful
- B.
Painless
Correct Answer
B. Painless -
- 31.
Can patients with SLE also have arthritis?
- A.
No, they never have SLE
- B.
Yes, but it is not erosive or inflammatory
Correct Answer
B. Yes, but it is not erosive or inflammatory -
- 32.
One of the earliest manifestations of patients with SLE with renal inolvment is:
- A.
Oliguria
- B.
Foul smelling urine
- C.
Peristent proteinuria
Correct Answer
C. Peristent proteinuria -
- 33.
Are there any neurological disorders associated with SLE?
- A.
No, there is no CNS involvement
- B.
Yes, they can have seizures
Correct Answer
B. Yes, they can have seizures -
- 34.
Does an ANA negative lupus exist?
- A.
Yes
- B.
No
Correct Answer
B. No -
- 35.
Patient with SLE can also have new onset psychosis?
- A.
Yes
- B.
No
Correct Answer
A. Yes -
- 36.
Which of the following tests specifically go along with SLE.
- A.
Positive ANA
- B.
Antibodies to ds-DNA
- C.
Antibodies to Smith antibody
- D.
Anticardiolipin antibodies
- E.
IgM or IgG, leukopenia, anemia
Correct Answer(s)
A. Positive ANA
B. Antibodies to ds-DNA
C. Antibodies to Smith antibody
D. Anticardiolipin antibodies
E. IgM or IgG, leukopenia, anemia -
- 37.
A positive ANA means a patient has LUPUS?
- A.
Yes
- B.
No
Correct Answer
B. NoExplanation
Lupus is a clinical diagnosis, you have to correlate the positive ANA to the clinical symptoms.Rate this question:
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- 38.
The larynx and trachea can also be nvolved in patients with SLE. Is this common or uncommon?
- A.
Common
- B.
Uncommon
Correct Answer
B. Uncommon -
- 39.
Jacob's arthropathy is:
- A.
SLE - nonerosive arthritis
- B.
SLE - erosive arthritis
Correct Answer
A. SLE - nonerosive arthritis -
- 40.
Is the deformitiy seen in SLE nonerosive arthiritis reversible?
- A.
Yes
- B.
No
Correct Answer
A. Yes -
- 41.
Although rare - What are the three most common life threatening consequences of SLE?
- A.
Nephritis
- B.
Respiratory depression
- C.
Thrombocytopenia
- D.
Cerebritis
Correct Answer(s)
A. NepHritis
C. Thrombocytopenia
D. Cerebritis -
- 42.
What would you tell you patient who has lupus?
- A.
Avoid the sun
- B.
Use suncscreen
- C.
Postprandal rinse or hydrogen peroxide
- D.
Use salivary substitutes
- E.
Lower your fluid intake
Correct Answer(s)
A. Avoid the sun
B. Use suncscreen
C. Postprandal rinse or hydrogen peroxide
D. Use salivary substitutes -
- 43.
What is the antimalarial drug that is used to treat SLE?
- A.
Doxycycline
- B.
Mefloquine
- C.
Hydroxychloroquine (plaquenil)
- D.
Primaquine
Correct Answer
C. Hydroxychloroquine (plaquenil)Explanation
200mg bid, can cause retinal toxicity, so also have opthalmology exam before starting.Rate this question:
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- 44.
What other medications can be used in the treatment of SLE?
- A.
Low dose methotrexate
- B.
Aziothioprine (imuran)
- C.
Cyclophsophamide
- D.
High dose steroid for serious visceral involvement
- E.
Topical and low dose steroids and NSAIDS
Correct Answer(s)
A. Low dose methotrexate
B. Aziothioprine (imuran)
C. CyclopHsopHamide
D. High dose steroid for serious visceral involvement
E. Topical and low dose steroids and NSAIDS -
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Feb 16, 2019Quiz Edited by
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