Connective Tissue Diseases (Msq Drill 183)
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- 1.
Is Sjogren syndrome a chronic or acute disorder?
- A.
Chronic
- B.
Acute
Correct Answer
A. Chronic -
- 2.
The immune system destroys what organs in Sjogren's dynsrome?
- A.
Kidneys
- B.
Pancreas
- C.
Endocrine glands
- D.
Exocrine glands
Correct Answer
D. Exocrine glands -
- 3.
Sjogrens syndrom is divided into primary and secondary. Which of the two is a diagnosis of exclusion?
- A.
Primary
- B.
Secondary
Correct Answer
A. Primary -
- 4.
Secondary Sjogren syndrome refers to the ______ complex that accompanies any of the connective tissue diseases such as xeropthalmia, keratoconjuctivitis, xerostomia with or without salivary gland enlanrgment.
- A.
A
- B.
Sicca
Correct Answer
B. Sicca -
- 5.
What is the most common connective tissue disease?
- A.
Sjjorgen syndrome
- B.
B
- C.
SLE
Correct Answer
C. SLEExplanation
Sjorgren is the second most common CTD.Rate this question:
-
- 6.
Since the exocrine glands are affected will patients with Sjorgren syndrome will have watery or dry eyes?
- A.
Watery eyes
- B.
Dry eyes
Correct Answer
B. Dry eyes -
- 7.
Can Sjorgren's affect the parotid gland?
- A.
Yes, in fact patrotid biopsy is more sensitive and specific
- B.
No, it does not affect the paroid gland
Correct Answer
A. Yes, in fact patrotid biopsy is more sensitive and specific -
- 8.
Sjogren's syndrome is associated with an increased risk of what disease?
- A.
A
- B.
B
- C.
C
- D.
Lymphoma
Correct Answer
D. LympHoma -
- 9.
Is Sjogren's more common in men or women?
- A.
Men
- B.
Women
Correct Answer
B. Women -
- 10.
What antibodies are associated with Sjogren's syndrome?
- A.
A
- B.
SS-A
- C.
B
- D.
SS-B
Correct Answer(s)
B. SS-A
D. SS-B -
- 11.
Can SS-A and SS-B also be seen in other CTD's
- A.
Yes, but they are more specific for Sjogren syndrome
- B.
No, they will only be seen in Sjogren
Correct Answer
A. Yes, but they are more specific for Sjogren syndrome -
- 12.
The diganostic ciriteria for Sjorgen's also incudes:
- A.
Dry eyes > 3 months or use of tear substitutes, or sensation of sand or gravel in eyes
- B.
Dry mouth > 3 months or swollen salivary glands or frequenst drinking of liquids to help in swallowing
- C.
Schirmer-I-test or Rose Bengal score
- D.
Mononuclear cells in glandular tissue
- E.
Abnormal salivary flow in the salivary glands or parotid gland
Correct Answer(s)
A. Dry eyes > 3 months or use of tear substitutes, or sensation of sand or gravel in eyes
B. Dry mouth > 3 months or swollen salivary glands or frequenst drinking of liquids to help in swallowing
C. Schirmer-I-test or Rose Bengal score
D. Mononuclear cells in glandular tissue
E. Abnormal salivary flow in the salivary glands or parotid gland -
- 13.
Do patients with Sjorgens have a high or low titer rheumatoid factor?
- A.
Low titer
- B.
High titer
Correct Answer
A. Low titer -
- 14.
How do you treat Sjogren's syndrome?
- A.
Saliva substitutes, artificaial tears
- B.
Increased oral fluid intake
- C.
Pilocaprine for the eyes to increase tears
- D.
Antifungals and close dental follow up
- E.
Same drugs as SLE - hydroxychloroquine, methotrexate and low dose immunosuppressive drugs.
Correct Answer(s)
A. Saliva substitutes, artificaial tears
B. Increased oral fluid intake
C. Pilocaprine for the eyes to increase tears
D. Antifungals and close dental follow up
E. Same drugs as SLE - hydroxychloroquine, methotrexate and low dose immunosuppressive drugs. -
- 15.
Systemis sclerosis is also known as _________ .
- A.
A
- B.
S
- C.
D
- D.
Scleroderma
Correct Answer
D. Scleroderma -
- 16.
Patients with sclerotic skin changes often accompanied by multisystem disease. True or false?
- A.
True
- B.
False
Correct Answer
A. True -
- 17.
A patient with scleroderma presents to your office complaining of pain in the digitis when they are exposed to cold and a white or bluish color. When rewarmed they trun red before they turn back to the normal color. You determine that this is:
- A.
A
- B.
Rreynaud's
Correct Answer
B. Rreynaud's -
- 18.
Patients with systemic sclerosis or scleroderma may have progressivwe fibrosis from increased deposition of _________________ in interstitium and intima of small alrteries and connective tissues.
- A.
A
- B.
Collagen
Correct Answer
B. Collagen -
- 19.
Is there a variation of scleroderma that is only cutaneous with no systemic involvement?
- A.
Yes
- B.
No
Correct Answer
A. Yes -
- 20.
Does scleroderma have a male or female proponderance?
- A.
Male
- B.
Female
Correct Answer
B. Female -
- 21.
So the typical patient with scleroderma will present with:
- A.
Reynaud's phenomenon
- B.
Edema fingers and hands
- C.
Skin thickening
- D.
Visceral manifestation - eg heartburn or gerd (mmost common GI complain), lung, heart, kidneys, & thyroid.
- E.
Arthralgias and muscle weakness
Correct Answer(s)
A. Reynaud's pHenomenon
B. Edema fingers and hands
C. Skin thickening
D. Visceral manifestation - eg heartburn or gerd (mmost common GI complain), lung, heart, kidneys, & thyroid.
E. Arthralgias and muscle weakness -
- 22.
What is the most common initial complaint of patient with scleroderma?
- A.
Dysphagia
- B.
Tight, thin lips with vertical perioral furrows
- C.
Trismus & transition zone around dental roots
- D.
Xerostomis, xerophthalmiz
- E.
Laryngela inolvement with hoarseness
Correct Answer
A. DyspHagia -
- 23.
**** Systemic scleroderma patients will have what antibody
- A.
A
- B.
Anti SCL- 70
Correct Answer
B. Anti SCL- 70 -
- 24.
Limited scleroderma:
- A.
A
- B.
B
- C.
C
- D.
Anti-centromere antibody
Correct Answer
D. Anti-centromere antibody -
- 25.
The antibodies of scleroderma AntiSCL-70 and anti-centromere antibodies do not always have to be present in order for you to make a diagnosis of scleroderma. True or false?
- A.
True
- B.
False
Correct Answer
A. True -
- 26.
Is sclerodactyly seen in early or late scleroderma?
- A.
Early
- B.
Late
- C.
Both
Correct Answer
C. Both -
- 27.
Is there an ybony involvement in sclerodactyly of the hands in patients with scleroderma?
- A.
Yes
- B.
No
Correct Answer
B. No -
- 28.
A rheumatological emergency in scleroderma is:
- A.
A
- B.
Scleroderma renal crisis
Correct Answer
B. Scleroderma renal crisisExplanation
Creatine level will be elevated and proteinuriaRate this question:
-
- 29.
**** What will you treat the patient presenting with a scleroderma renal crisis?
- A.
A
- B.
ACE inhibitors
Correct Answer
B. ACE inhibitors -
- 30.
Treatment of scleroderma includes:
- A.
Same as for SLE - hydrocloroquinone and methotrexate etc..
- B.
Using gloves and prostaglandian for raynaud's
- C.
Calcium channel blockers, tropical NTG
Correct Answer(s)
A. Same as for SLE - hydrocloroquinone and methotrexate etc..
B. Using gloves and prostaglandian for raynaud's
C. Calcium channel blockers, tropical NTG -
- 31.
CTD diseases are ____________ diseases.
- A.
Uni system
- B.
Multi system
Correct Answer
B. Multi system -
- 32.
What is key to the pathegenesis and therapy of CTD's
- A.
A
- B.
S
- C.
Immune mechanisms
Correct Answer
C. Immune mechanisms -
- 33.
Diagnosis of CTD's is __________ based using criteria.
- A.
Clinically
- B.
B
Correct Answer
A. Clinically -
- 34.
Treatment of connective tissue disease is specific or non-specific
- A.
Specific
- B.
Non-specific
Correct Answer
B. Non-specificExplanation
Treatment is aimed at specific manifestations of the disease.Rate this question:
-
- 35.
Dermatomyositis is an inflammatory muscle disease. Do the patients present with muscle pain or weakness?
- A.
Pain
- B.
Weakness
Correct Answer
B. Weakness -
- 36.
Patients with polymyositis may present with:
- A.
Difficulty phonating
- B.
Nasal regurgitating
- C.
Aspiration penumonitis
- D.
Rash
Correct Answer(s)
A. Difficulty pHonating
B. Nasal regurgitating
C. Aspiration penumonitis
D. Rash -
- 37.
What three modalities are used to treat polymyositis and dermotomyositis?
- A.
Steroids
- B.
Methotrexate
- C.
C
- D.
Immunosuppressants
Correct Answer(s)
A. Steroids
B. Methotrexate
D. Immunosuppressants -
- 38.
What is the sub serological marker for inflammatory muscle diseases?
- A.
A
- B.
Anti-Jo-1
Correct Answer
B. Anti-Jo-1 -
- 39.
If you have SLe, scleroderma and polymyositis then you probably have:
- A.
A
- B.
S
- C.
Mixed connectivce tissue disease
Correct Answer
C. Mixed connectivce tissue disease -
- 40.
Usually patients with mixed connective tissue diseases will have high titers of:
- A.
Anti-U1RNP
- B.
S
Correct Answer
A. Anti-U1RNP -
- 41.
What do you treat mixed connective tissue diseases with?
- A.
A
- B.
High dose steroids
Correct Answer
B. High dose steroids -
- 42.
Polyarteritis nodosa is a prototype of:
- A.
A
- B.
B
- C.
Vasculitis
Correct Answer
C. Vasculitis -
- 43.
Necrotizing vasculitis of the upper airways affecting the sinuses, sicus cavity, lower airways and kidneys is known as:
- A.
Wegener;s granulomatosis
- B.
B
Correct Answer
A. Wegener;s granulomatosis -
- 44.
What is the antibody for Wegener's granulomatoma?
- A.
A
- B.
S
- C.
S
- D.
Antineutrophil cytoplasmic antibody (c-ANCA)
Correct Answer
D. AntineutropHil cytoplasmic antibody (c-ANCA) -
- 45.
In order to cofirm a diagnosis of Wegener's you need to have a:
- A.
A
- B.
D
- C.
Biopsy
Correct Answer
C. Biopsy -
- 46.
Polymyositis plus a rash is:
- A.
A
- B.
Dermatomyositis
Correct Answer
B. Dermatomyositis -
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Feb 07, 2019Quiz Edited by
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