Nsaids - Part 2 (Msq Drill 176)

SettingsSettings
Please wait...
  • 1/50 Questions

    Therefore Aspirin inhibits platelet function for the life of the platelet. True or false?

    • True
    • False
Please wait...
Nsaids - Part 2 (Msq Drill 176) - Quiz
About This Quiz

Medicalschoolquizzes. Com

Quiz Preview

  • 2. 

    Can ASA contribute to Salicylism?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 3. 

    What should you watch for with tylenol?

    • Hepatotoxicity

    • Nephrotoxocity

    Correct Answer
    A. Hepatotoxicity
  • 4. 

    Are elderly patients at a higher risk of GI erosion from NSAIDS?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 5. 

    Inhibiting COX 1 leads to edema because of increased ADH. Inhibiting COX 2 also leads to edema. Is the mechanism exactly the same?

    • Yes, ADH is involved in both mechanisms

    • No, sodium retention causes edema in COX 2 inhibition

    Correct Answer
    A. No, sodium retention causes edema in COX 2 inhibition
  • 6. 

    Analegesic nephropathy can also occur due to NSAID administration. True or false?

    • True

    • False

    Correct Answer
    A. True
  • 7. 

    Would you give an NSAID to a patient that has a history of ASA induced bronchospasm?

    • Yes

    • No

    Correct Answer
    A. No
  • 8. 

    Aspirin is a platelet inhibitor. True or false?

    • True

    • False

    Correct Answer
    A. True
  • 9. 

    How does Aspirin prevent clotting?

    • It reversibly acetylates COX

    • It irreversibly aceylates COX

    Correct Answer
    A. It irreversibly aceylates COX
  • 10. 

    Do platelets have a nuclei?

    • Yes

    • No

    Correct Answer
    A. No
  • 11. 

    If you give a low dose of Aspirin (which will be hereto referred to as ASA) is this more selective for COX 1 or COX 2?

    • Low dose ASA selective for COX 1

    • Low dose ASA selective for COX 2

    Correct Answer
    A. Low dose ASA selective for COX 1
  • 12. 

    In addition to edema, inhibiting COX 2 will also affect fluid and electrolyte balance. True or false?

    • True

    • False

    Correct Answer
    A. True
  • 13. 

    Can you get headaches from taking NSAIDS?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 14. 

    Does ADH upregulation lead to fluid retention or fluid excretion

    • Fluid retention

    • Fluid excretion

    Correct Answer
    A. Fluid retention
  • 15. 

    Can ASA induce bronchospasm?

    • Yes

    • No

    Correct Answer
    A. Yes
  • 16. 

    The following drugs are all COX 2 drugs. Which drug is COX 2 specific?

    • Celexocib ( celebrex)

    • Meloxicam (mobic)

    • Nabemutone (Relafen)

    • Edotolac (lodine)

    Correct Answer
    A. Celexocib ( celebrex)
  • 17. 

    What method is better for administering COX inhibitors?

    • High doses for the shortest amount of time

    • Low doses for the shortest amount of time

    • Low doses over a long time

    Correct Answer
    A. Low doses for the shortest amount of time
  • 18. 

    If a pateint has a GI risk which COX will you opt for. You will either give the COX inhibitor at the normal dose or with a PPI if you use a classic dose?

    • COX 1

    • COX 2

    Correct Answer
    A. COX 2
  • 19. 

    Do platelets make new COX after Aspirin has IRREVERSIBLY reversed their COX?

    • Yes, it is a continuous process

    • No, they cannot make new COX because they have no nuclei.

    Correct Answer
    A. No, they cannot make new COX because they have no nuclei.
  • 20. 

    A child taking ASA is at risk for:

    • Steven Johnson's syndrome

    • Reye's syndrome

    • Chronic fatigue syndrome

    • Fibromyalgia

    Correct Answer
    A. Reye's syndrome
  • 21. 

    Which patients are at risk for complications if they take NSAIDs?

    • A patient with hypertension

    • A patient who is 20 years old and has bursitis, and is dehydrated and diabetic

    • A patient with CHF

    • A patient with impaired kidney function

    • An old patient

    Correct Answer(s)
    A. A patient with hypertension
    A. A patient who is 20 years old and has bursitis, and is dehydrated and diabetic
    A. A patient with CHF
    A. A patient with impaired kidney function
    A. An old patient
    Explanation
    HARDD - Htn, aged, renal impairement, dehydrated/diuresed. diabetic.)

    Rate this question:

  • 22. 

    Whereas misoprostol 9cytotec) is a prostaglandin analog, ____________ is a proton pump inhibitor.

    • Lasix (furosemide)

    • Protonix (pantoprazole)

    • Zantac (ranitidine)

    Correct Answer
    A. Protonix (pantoprazole)
    Explanation
    drugs ending in prazole. Zantac is a histamine H2 receptor agonist not a PPI.

    Rate this question:

  • 23. 

    Acetaminophen has a HUGE anti-inflammatory effect. True or false?

    • True

    • False

    Correct Answer
    A. False
    Explanation
    It has minimal anti-inflammatory effect.

    Rate this question:

  • 24. 

    COX 1 or COX 2?increased GI erosionDecreased renal perfusiondecreased platelet aggregation

    • COX 1

    • COX 2

    Correct Answer
    A. COX 1
  • 25. 

    Does tylenol have minimal or severe GI effects?

    • Minimal GI effects

    • Severe GI effects

    Correct Answer
    A. Minimal GI effects
  • 26. 

    What is the specific antidote for acetaminophen?

    • Atropine

    • Vitamin K

    • Benadryl

    • Acetylcysteine

    Correct Answer
    A. Acetylcysteine
    Explanation
    AKA mucomyst

    Rate this question:

  • 27. 

    What is the acetominophen toxic intermediate that is capable of necrotizing hepatocytes?

    • Organophosphate

    • NAPQ 1

    • 3-methylindole

    Correct Answer
    A. NAPQ 1
  • 28. 

    What is the hallmark of salicylism?

    • Blindness

    • Weight gain

    • Bleeding

    • Tinnutis

    Correct Answer
    A. Tinnutis
  • 29. 

    When renal perfusion is decreased, is ADH secretion upregulated or downregulated?

    • ADH secretion is upregulated

    • ADH secretion is downregulated

    Correct Answer
    A. ADH secretion is upregulated
  • 30. 

    Celexocib (celebrex) should not be administered to a patient with ______ allergy.

    • Sulfonamide

    • Shell fish

    • Pottasium

    • Peanut

    Correct Answer
    A. Sulfonamide
  • 31. 

    Do you see decreased renal perfusion with COX 1 or COX 2 or both?

    • COX 1 only

    • COX 2 only

    • Both COX 1 and COX 2

    Correct Answer
    A. Both COX 1 and COX 2
  • 32. 

    Would you give a patient presenting with acute gout acetaminophen?

    • Yes, it will reduce the pain

    • No, it is not useful for acute gout

    Correct Answer
    A. No, it is not useful for acute gout
  • 33. 

    What is salisylism?

    • Toxic overdose of ibuprofen

    • Toxic effects of overdosage with acetylsalicylic acid only

    • Toxic effects of overdosage with salicylic salts

    Correct Answer
    A. Toxic effects of overdosage with salicylic salts
  • 34. 

    Therefore giving a patient a COX 1 inhibitor, will decrease renal perfusion, increase ADH secretion and thus lead to which symptoms?

    • Edema

    • Polyuria

    • Hypertension

    • Hypotension

    Correct Answer(s)
    A. Edema
    A. Hypertension
  • 35. 

    Ibuprofen, naproxen and ketorolax(toradol) are all non specific COX inhibitors. Of these three drugs which has has the MOST COX 1 selectivity and thus has the greatest rsik of GI erosion?

    • Ibuprofen

    • Naproxen

    • Ketorolac (toradol)

    Correct Answer
    A. Ketorolac (toradol)
  • 36. 

    Macrophage chemotaxis is mediated by COX enzymes. If you give a patient low dose ASA, does this also block the mediatory effect of COX 2 on macrophages?

    • Yes

    • No

    Correct Answer
    A. No
  • 37. 

    Giving low dose ASA may contribute to ASA resistance. True or false?

    • True

    • False

    Correct Answer
    A. True
  • 38. 

    Since ketorolac (toradol) has the greatest risk of GI erosion it should only be administered for ___ days.

    • 1

    • 2

    • 3

    • 4

    • 5

    Correct Answer
    A. 5
  • 39. 

    If you inhibit COX _____ you decrease renal perfusion via  EFFERENT constriction.

    • 1

    • 2

    Correct Answer
    A. 1
    Explanation
    This can lead to ARB and elevated BP as covered in part 1 of this quiz. This is worse when combined with ACEI-ARBs.

    Rate this question:

  • 40. 

    ASA: salicylic acid or acetylsalicylic acid?

    • Salicylic acid

    • Acetylsalicylic acid

    Correct Answer
    A. Acetylsalicylic acid
    Explanation
    same compound but it is acetylated in ASA.

    Rate this question:

  • 41. 

    Tinnutis is the hallmark of salicylism. What other symptoms can be present? check all that apply.

    • Hyperpyrexia

    • Sweating

    • Hyperventilation

    • Metabolic acidosis with respiratory alkalosis

    • Metabolic alkalosis with respiratory acidosis

    Correct Answer(s)
    A. Hyperpyrexia
    A. Sweating
    A. Hyperventilation
    A. Metabolic acidosis with respiratory alkalosis
    Explanation
    hyperpyexia - abnormally high fever.
    "Alive until dead."

    Rate this question:

  • 42. 

    Taking misoprostol (cytotec) whilst taking an NSAID can prevent toxicity. What class does misoprostol belong to?

    • Proton pump inhibitor

    • Prostaglandin inhibitor

    • Diuretic

    • Anti hypertensive

    Correct Answer
    A. Prostaglandin inhibitor
  • 43. 

    Which of the following increases the risk of GI erosion?

    • Duplicating and NSAID dose

    • Taking NSAIDS when you have a prior history of GI or cardiovascular disease

    • Taking an NSAID concurrently with an SSRI

    • Taking an NSAID for arthritis

    • Taking NSAIDS with steroids

    Correct Answer(s)
    A. Duplicating and NSAID dose
    A. Taking NSAIDS when you have a prior history of GI or cardiovascular disease
    A. Taking an NSAID concurrently with an SSRI
    A. Taking an NSAID for arthritis
    A. Taking NSAIDS with steroids
  • 44. 

    What is often the FIRST symptom of NSAID toxicity?

    • Mild GI bleed

    • Chronic GI bleed

    • Life threatening GI bleed

    Correct Answer
    A. Life threatening GI bleed
    Explanation
    Most people are asymptomatic initially

    Rate this question:

  • 45. 

    It is better to take a low dose antiacid with an NSAID. True or false?

    • True, a low dose antiacid will decrease the risk of GI erosion

    • False, concurrent low dose antacid intake with an NSAID puts you at risk for GI erosion

    Correct Answer
    A. False, concurrent low dose antacid intake with an NSAID puts you at risk for GI erosion
  • 46. 

    Which of the following is a CNS manifestation that you might observe in a patient with systemic lupus eythmatosus who is also taking NSAIDS?

    • Psychosis

    • Septic meningitis

    • Avascular necrosis

    • Aseptic meningitis

    • Subdural hematoma

    Correct Answer
    A. Aseptic meningitis
  • 47. 

    Which of the following are classes of drugs or drugs that NSAIDS seem to interfere with?

    • Lithium - cause decreased elimjination

    • Diuretics

    • Antihypertensives

    • All antipsychotics

    Correct Answer(s)
    A. Lithium - cause decreased elimjination
    A. Diuretics
    A. Antihypertensives
  • 48. 

    Which of the following drugs are non selective COX acting drugs?

    • Ibuprofen

    • Naproxen

    • Ketorolax (toradol)

    • ASA

    • Meloxicam (mobic)

    Correct Answer(s)
    A. Ibuprofen
    A. Naproxen
    A. Ketorolax (toradol)
  • 49. 

    What can you take to try and prevent GI erosion is you going to take an NSAID?

    • An ASA every morning.

    • Misoprostol (cytotec)

    • Omeprazole (prilosec)

    • Lasix (furosemide)

    Correct Answer(s)
    A. Misoprostol (cytotec)
    A. Omeprazole (prilosec)

Quiz Review Timeline (Updated): +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Feb 16, 2019
    Quiz Edited by
    ProProfs Editorial Team
  • Apr 27, 2010
    Quiz Created by
Back to Top Back to top
Advertisement