1.
Osteoporosis is the most common METABOLIC bone disease in:
Correct Answer
D. The elderly
2.
Is osteoporosis a systemic or a localized disease?
Correct Answer
A. Systemic
3.
What is osteoporosis characterized by low bone density or low bone quality?
Correct Answer
A. Low bone density or mass
4.
So, is the bone quality in osteoporosis normal?
Correct Answer
A. Yes
5.
If a localized area has low bone density, does this meet the criteria for osteoporosis?
Correct Answer
B. No, even though the bone density is low it does not meet the criteria as osteoporosis has to be a systemic disease
6.
So, the consequences of osteoporosis include:
Correct Answer(s)
A. Bone fragility
C. Fracture
7.
What does osteopenia mean?
Correct Answer
C. Mild thinning of the bone mass
8.
Because patients with osteoporosis have low bone density they have fragile bones and are prone to fractures. According to the national National Osteoporosis foundation ostoporosis is defined as:
Correct Answer
A. Below 2 standard deviations
9.
The national osteoporosis foundation defines osteopenia as up to 2 standard deviations below young normal females. True or false?
Correct Answer
A. True
10.
What is the WHO classification for Osteoporosis?
Correct Answer
A. Bone mass density over 2.5 standard deviations below the normal female mean
11.
Osteopenia is classified as a bone mass density that is __________ standard deviations below the young normal female mean.
Correct Answer
B. 1-2.5
12.
When you tell a patient that they have osteomalacia, you are essentially telling them that they have a problem with their bone:
Correct Answer
B. Quality
Explanation
Problems with bone density lead to osteoporosis.
13.
Osteoporosis is defined as a skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fractures. Bone strength reflects the intergration of what two main features?
Correct Answer(s)
B. Bone quality
D. Bone density
14.
So, bone strength + bone density + bone quality. True or false?
Correct Answer
A. True
15.
Is there bone thinning in osteoporosis?
Correct Answer
A. Yes
16.
Both the cortical and trabecular parts of bone are affected by osteoporosis. Which part is affected more?
Correct Answer
A. Trabeculae
17.
Is estrogen a mjor bone deteriorator or a bone protector?
Correct Answer
B. Protector
18.
Since estrogen is a bone protector women who are postmenopausal are at a high risk of getting osteoporosis as they have an ______ amount of estrogen.
Correct Answer
B. Decreased
19.
Aging and postmenopause are ________ causes of osteoporosis.
Correct Answer
A. pHysiologic
20.
What is the number secondary cause of osteoporosis?
Correct Answer
B. Steroids
21.
If you are giving your patient a dose of steroids that is above _______ mg, it is extremely important to include a concomitant prophylaxis against osteoporosis such as Actonel or Boniva.
Correct Answer
D. 7.5mg
22.
Everything else that causes osteoporosis besides aging and postmenopause is considered a ______ cause of osteoporosis.
Correct Answer
B. Secondary
23.
Which of the following are some secondary risk factors for osteoporosis?
Correct Answer(s)
A. Depo provera
B. Dilantin
C. Chronic heparin therapy
D. Chronic protein or clacium deficiency
Explanation
Patients with an excess of thyroid hormone are at risk for osteoporosis.
24.
Can neoplasms activate osteoclast activity leading to osteoporosis?
Correct Answer
A. Yes
25.
Which of the following are other risk factors for osteoporosis?
Correct Answer(s)
B. Hypocalcemia
C. Smoking and alcohol
D. Family history of fractures
E. Female
Explanation
Patients who have a low body mass have a higher risk of osteoporosis.
26.
Which group of drugs top the list of drugs that can cause osteoporosis?
Correct Answer
D. Glucocorticoids
27.
So heredity and your body frame can put you at risk for osteoporosis?
Correct Answer
A. Yes
28.
Men do NOT get osteoporosis. True or false?
Correct Answer
B. False
Explanation
In fact men are underdiagnosed.
29.
Why might a man be at risk for osteoporosis? Check all that apply.
Correct Answer(s)
A. Low testosterone levels
C. Heavy alcohol consumption
D. Smoking
E. Glucocorticoid use
30.
The majority of men with osteoporosis have disorders that are known to produce bone loss. Which of the following are some of these disorders?
Correct Answer(s)
A. Hyperparathyroidism
C. Malignancies
D. Intestinal disorders
E. Conditions resulting in immobilization
31.
The less you move around, the greater the chance of developing osteoporosis. True or false?
Correct Answer
A. True
32.
Can your risk of developing osteoporosis be affected by your race?
Correct Answer
A. Yes
33.
In studies on white women and the fracture risk associated with the aging process, what type of fractures increased the most as women grew older?
Correct Answer
A. Vertebral
34.
Do hip fractures also increase exponentially as women age?
Correct Answer
A. Yes
35.
Which of the following are also other secondary causes of osteoporosis?
Correct Answer(s)
A. Endocrine disorders such as cushings and hyperthyroidism
B. Vitamin D deficiency
C. Hepatic and renal dysfunction
D. Malnutrition, anorexia nervosa
E. Celiac disease and other causes of malabsorption
36.
Between estrogen and testosterone which one is protective from osteoporosis?
Correct Answer
C. Both estrogen and testosterone
37.
How many women and men in the US currently have osteoporosis respectively?
Correct Answer
D. 8 and 2 million
38.
How many americans currently have low bone mass?
Correct Answer
E. 34 million
39.
What percentage of women over the age of 50 will sustain a fracture in their lifetime?
Correct Answer
E. 50%
40.
Testing and increased life expectancy has seen higher numbers of people diagnosed today than before. True or false?
Correct Answer
A. True
41.
The major health care cost of osteoporosis comes from:
Correct Answer
C. Fractures
42.
Osteoporosis causes over how may million fractures in men and women over the age of 50?
Correct Answer
B. 2
43.
What two types of cells are associated with osteoporosis?
Correct Answer(s)
A. Osteoblasts
C. Osteoclasts
44.
Of the two types of cells associated with osteoporosis, which one has increased activity in malignancies?
Correct Answer
B. Osteoclasts
45.
Which cell is responsible for bone resorption?
Correct Answer
A. Osteoclasts
46.
Between cortical and trabeculae bone which one has a higher turnover?
Correct Answer
A. Trabecular
47.
Although trabecular bone has 80% turnover it only comprises 20% of the skeletal mass. True or false?
Correct Answer
A. True
48.
Calcium is an intergral component of the bone matrix. True or false?
Correct Answer
A. True
49.
The following are all biochemical markers of bone metabolism. Which ones are involved in bone formation?
Correct Answer(s)
B. Serum osteocalcin
E. Serum bone specific alkaline pHospHatase
Explanation
the rest are responsible for bone resorption.
50.
Which of the following are clinical features of spinal osteoporosis?
Correct Answer(s)
A. Numerous warning signs
B. Height loss and dorsal kypHosis
C. Paraspinal muscle pain
D. Restrictive lung disease
E. Protruberant lower abdomen with early satiety, bloating and nausea
Explanation
spinal osteoporosis has NO early warning signs.