1.
Glioblastoma affect which type of brain cells?
Correct Answer
C. Astrocytes
Explanation
Astrocytes are a type of brain cells that provide support and nourishment to neurons. They also play a crucial role in maintaining the blood-brain barrier, which protects the brain from harmful substances. Glioblastoma is a type of brain tumor that originates from astrocytes. Therefore, it can be concluded that glioblastoma affects astrocytes specifically.
2.
Which of the following is amongst the treatment measures for glioblastoma?
Correct Answer
D. All of the above
Explanation
All of the options listed (radiation therapy, chemotherapy, and intensity modulated radiation therapy) are treatment measures for glioblastoma. Glioblastoma is a type of brain cancer that is typically treated with a combination of these therapies. Radiation therapy uses high-energy radiation to kill cancer cells, while chemotherapy uses drugs to kill cancer cells. Intensity modulated radiation therapy is a specialized form of radiation therapy that delivers precise doses of radiation to the tumor while minimizing damage to surrounding healthy tissue. Therefore, all of these options are valid treatment measures for glioblastoma.
3.
What is true about glioblastoma?
Correct Answer
C. It commonly affect white males
Explanation
Glioblastoma commonly affects white males.
4.
Which medication is used frequently as the treatment measure for glioblastoma?
Correct Answer
A. Temozolomide
Explanation
Temozolomide is frequently used as a treatment measure for glioblastoma. Glioblastoma is an aggressive type of brain cancer, and Temozolomide is an oral chemotherapy drug that is often prescribed in combination with radiation therapy. It works by damaging the DNA of cancer cells, inhibiting their growth and causing them to die. Temozolomide has been shown to improve survival rates and is considered a standard treatment option for glioblastoma.
5.
Which of the following is among the risk factor for glioblastoma?
Correct Answer
C. Neurofibromatosis
Explanation
Neurofibromatosis is a genetic disorder that increases the risk of developing glioblastoma, a type of brain tumor. Individuals with neurofibromatosis have a higher likelihood of developing tumors in the brain and spinal cord, including glioblastoma. Depression and obesity are not directly associated with an increased risk of glioblastoma, making neurofibromatosis the correct answer.
6.
How is a glioblastoma is detected?
Correct Answer
D. All of the above
Explanation
A glioblastoma, a type of brain tumor, can be detected through various methods. A CT scan uses X-rays to create detailed images of the brain, allowing doctors to identify any abnormalities. A biopsy involves taking a sample of the tumor tissue for examination under a microscope, providing a definitive diagnosis. An MRI scan uses magnetic fields and radio waves to produce detailed images of the brain, which can help in detecting glioblastomas. Therefore, all of the mentioned methods (CT scan, biopsy, and MRI scan) can be used to detect a glioblastoma.
7.
Which of the following is amongst the symptoms of glioblastoma?
Correct Answer
D. Headaches and seizures
Explanation
Glioblastoma is a type of brain tumor that can cause various symptoms. Headaches and seizures are common symptoms of glioblastoma. Headaches may be persistent and severe, often worse in the morning or with physical activity. Seizures can occur due to the tumor's effect on brain function. These symptoms can be caused by increased pressure within the skull as the tumor grows and compresses surrounding structures. Unusual weight gain and diarrhea are not typically associated with glioblastoma. Swelling may occur in the brain, but it is not specifically mentioned as a symptom of glioblastoma in this question.
8.
At what age is there a common onset of glioblastoma?
Correct Answer
B. 64 years
Explanation
Glioblastoma is a type of brain tumor that is more commonly diagnosed in older adults. The average age of onset for glioblastoma is around 64 years. This means that a significant number of individuals diagnosed with glioblastoma are around this age. It is important to note that glioblastoma can occur at any age, but the likelihood increases with age.
9.
What is the common life expectancy of patients suffering from glioblastoma?
Correct Answer
D. 8 months - 12 months
Explanation
Patients suffering from glioblastoma, a type of aggressive brain cancer, typically have a common life expectancy of 8 months to 12 months. Glioblastoma is known for its rapid progression and poor prognosis, with most patients experiencing a decline in health within a year of diagnosis. Treatment options are limited and often focus on palliative care to manage symptoms and improve quality of life. The short life expectancy is due to the aggressive nature of the cancer and its resistance to treatment.
10.
Which of the following is associated with longer survival amongst patients with glioblastoma?
Correct Answer
A. A good initial Karnofsky performance score (KPS) and MGMT methylation
Explanation
A good initial Karnofsky performance score (KPS) and MGMT methylation are associated with longer survival amongst patients with glioblastoma. The Karnofsky performance score is a measure of a patient's functional status and overall well-being. A higher initial KPS indicates better overall health and functioning, which can contribute to improved survival. MGMT methylation refers to the methylation of the MGMT gene, which is involved in DNA repair. Methylation of the MGMT gene is associated with increased sensitivity to chemotherapy, which can improve treatment outcomes and survival rates for patients with glioblastoma.