Nondisjunction and chromosomal Abnormalities quiz
Do you know about nondisjunction and chromosomal abnormalities? Take this nondisjunction and chromosomal abnormalities quiz to test your knowledge. Basically, nondisjunction and chromosomal abnormality are related to the function of chromosomes. If you want to test your knowledge of these abnormalities, this quiz will be a great help. Go for it and try this quiz. All the best for this practice test. Do share the quiz with others who wish to test their knowledge.
- 1.
Which of the following statements is NOT true about Karyotypes?
- A.
Sex chromosomes are found at the end
- B.
Having missing or extra chromosomes does not indicate a disorder
- C.
A normal karyotype has 46 chromosomes or 23 pairs
- D.
Chromosomes (pairs 1-22) are arranged by size
Correct Answer
B. Having missing or extra chromosomes does not indicate a disorderExplanation
This statement is not true because having missing or extra chromosomes can indicate a disorder. For example, Down syndrome is caused by an extra copy of chromosome 21. Additionally, missing or extra chromosomes can lead to other genetic disorders and abnormalities.Rate this question:
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- 2.
What could be the result of nondisjunction?
- A.
Trisomy conditions
- B.
Monosomy conditions
- C.
Additional sex chromosomes
- D.
All of the above
Correct Answer
D. All of the aboveExplanation
Nondisjunction is the failure of chromosomes to separate properly during cell division. This can result in various genetic conditions. Trisomy conditions occur when there is an extra copy of a chromosome, such as Down syndrome (trisomy 21). Monosomy conditions occur when there is a missing copy of a chromosome, such as Turner syndrome (monosomy X). Nondisjunction can also lead to the presence of additional sex chromosomes, such as Klinefelter syndrome (XXY) or Turner syndrome (X0). Therefore, all of the options mentioned (trisomy conditions, monosomy conditions, additional sex chromosomes) can be the result of nondisjunction.Rate this question:
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- 3.
It is likely that as many as __________ newborn infants inherit a chromosomal abnormality.
- A.
1 in 118
- B.
1 in 57
- C.
1 in 1000
Correct Answer
A. 1 in 118Explanation
Approximately 1 in 118 newborn infants are likely to inherit a chromosomal abnormality. This suggests that there is a relatively high prevalence of chromosomal abnormalities among newborns.Rate this question:
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- 4.
What can occur if the chromosomes fail to separate correctly during the anaphase of meiosis?
- A.
Meiosis never completes
- B.
Chromosomes of the sex cell are halved
- C.
Extra chromosomes are found in the sex cell
- D.
Chromosomes of the sex cell are doubled
Correct Answer
C. Extra chromosomes are found in the sex cellExplanation
During the anaphase of meiosis, chromosomes are supposed to separate correctly and move to opposite poles of the cell. However, if they fail to separate correctly, it can result in extra chromosomes being found in the sex cell. This is known as nondisjunction, where chromosomes do not separate evenly, leading to an abnormal number of chromosomes in the resulting sex cell. This can have significant consequences, as it can lead to genetic disorders or abnormalities in offspring if the abnormal sex cell is involved in fertilization.Rate this question:
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- 5.
If a child had a karyotype that had 23 + 23 + 23 chromosomes or 23 + 24, it would be:
- A.
An irregular number of chromosomes
- B.
Within the range of normal
- C.
A structural modification in the chromosomes
- D.
None of the above
Correct Answer
A. An irregular number of chromosomesExplanation
If a child had a karyotype with 23 + 23 + 23 chromosomes or 23 + 24, it would be considered an irregular number of chromosomes. A normal karyotype for a human has 46 chromosomes, with 23 pairs. Any deviation from this number would be considered abnormal and indicate an irregular number of chromosomes.Rate this question:
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- 6.
Down's syndrome occurs because of a(n)
- A.
Additional 21st chromosome
- B.
Additional 18th chromosome
- C.
Extra sex chromosome
- D.
Missing sex chromosome
Correct Answer
A. Additional 21st chromosomeExplanation
Down's syndrome occurs because of an additional 21st chromosome. Normally, a person has two copies of each chromosome, but individuals with Down's syndrome have three copies of chromosome 21. This extra genetic material disrupts the normal development and causes the characteristic physical and intellectual disabilities associated with the syndrome.Rate this question:
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- 7.
The phase in mitosis where chromosomes move away and are pulled apart by spindles to opposite sides of the cell.
- A.
Prophase
- B.
Telephase
- C.
Metaphase
- D.
Anaphase
Correct Answer
D. AnapHaseExplanation
Anaphase is the correct answer because it is the phase in mitosis where the chromosomes move away from each other and are pulled apart by spindle fibers towards opposite poles of the cell. During anaphase, the sister chromatids separate and become individual chromosomes, which are then pulled towards the opposite ends of the cell. This movement ensures that each daughter cell receives the correct number of chromosomes during cell division.Rate this question:
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- 8.
What would you call the failure of one or more pairs of sister chromatids to separate normally during meiosis?
- A.
Anaphase I
- B.
Nondisjunction
- C.
Nondiploidy
- D.
Karyotype
Correct Answer
B. NondisjunctionExplanation
Nondisjunction refers to the failure of sister chromatids to separate properly during meiosis. This can result in an abnormal distribution of chromosomes in the resulting gametes, leading to genetic disorders such as Down syndrome. Anaphase I, on the other hand, is a phase of meiosis where homologous chromosomes separate, not sister chromatids. Nondiploidy refers to an abnormal number of chromosomes, and karyotype is a visualization of an individual's chromosomes. Therefore, the correct answer is nondisjunction.Rate this question:
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- 9.
A structural modification of a chromosome might be:
- A.
A miscarriage or spontaneous abortion
- B.
A karyotype
- C.
A break in a chromatid arm and its separation from its chromosome
- D.
All of the above
Correct Answer
C. A break in a chromatid arm and its separation from its chromosomeExplanation
A structural modification of a chromosome refers to any alteration in the normal structure of a chromosome. This can include a break in a chromatid arm and its separation from its chromosome, which is known as a chromosomal deletion. Miscarriage or spontaneous abortion is not a structural modification of a chromosome but rather a pregnancy loss. A karyotype, on the other hand, is a visual representation of the chromosomes in an individual's cells and can be used to detect structural abnormalities. Therefore, the correct answer is a break in a chromatid arm and its separation from its chromosome.Rate this question:
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- 10.
Inherited chromosomal abnormalities usually result from:
- A.
A failure of the mother's uterus and placenta in carrying a fetus to full term
- B.
Inadequate nutrition and medical care during early infancy
- C.
Defective sperm or ova
- D.
None of the above
Correct Answer
C. Defective sperm or ovaExplanation
Inherited chromosomal abnormalities usually result from defective sperm or ova. This means that the abnormalities are passed down from the parents to their offspring through the genetic material in the sperm or egg cells. These abnormalities can lead to various genetic disorders or conditions in the child, as the genetic information is not properly transmitted or may be altered.Rate this question:
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Aug 16, 2023Quiz Edited by
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Nov 25, 2022Quiz Created by
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