Glycolysis Trivia Questions

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  • 1/27 Questions

    How does glycolysis make ATP directly?

    • When enzymes transfer phosphate groups from fuel molecules to ADP
    • When RNA transfer phosphate groups from fuel molecules to ADP
    • When aminoacids transfer phosphate groups from fuel molecules to ADP
    • When DNA transfer phosphate groups from fuel molecules to ADP
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About This Quiz

When glucose breaks to create energy, the process is called glycolysis, and it takes place in the presence or absence of oxygen. This trivia quiz has questions on glycolysis. If you need to refresh your memory on this topic, worry not, as the quiz questions below are perfect for helping you polish up on whatever you already know. How about you give it a try and see how well you do? All the best!

Glycolysis Trivia Questions - Quiz

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  • 2. 

    The decarboxylation of Pyruvate, and the oxidation of acetate takes place in the:

    • Ribosomal matrix

    • Substrate matrix

    • Mitochondrial matrix

    • Cytoplasm

    Correct Answer
    A. Mitochondrial matrix
    Explanation
    The decarboxylation of Pyruvate and the oxidation of acetate are metabolic processes that occur during cellular respiration. These processes take place in the mitochondrial matrix, which is the innermost compartment of the mitochondria. The mitochondrial matrix contains enzymes that are involved in the breakdown of pyruvate and acetate, leading to the production of ATP through the citric acid cycle and oxidative phosphorylation. The mitochondrial matrix provides an optimal environment for these reactions to occur, allowing for efficient energy production.

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  • 3. 

    What is the meaning of fermentation?

    • The anaerobic harvest of food energy

    • The aerobic harvest of food energy

    • The use of ATP from cellular respiration

    • None of the above

    Correct Answer
    A. The anaerobic harvest of food energy
    Explanation
    Some of our cells can actually work because of this and also muscles

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  • 4. 

    Put the reactions of glycolysis in the right order in Stage 1 (preparatory stage)

    • 1.Phosphoglucose isomerase, 2. phosphofructokinase, 3. Aldolase, 4. Hexokinase, 5. Triosephosphate Isomerase

    • 1. Hexokinase 2. Phosphoglucose isomerase 3. phosphofuctokinase 4. Aldoase 5. Triose Phosphate Isomerase

    • 1. Phosphoglucose isomerase 2. Hexokinase 3. Phosphofructokinase 4, Aldolase 5. Triose Phosphate Isomerase

    • None of the above

    Correct Answer
    A. 1. Hexokinase 2. Phosphoglucose isomerase 3. phosphofuctokinase 4. Aldoase 5. Triose Phosphate Isomerase
    Explanation
    In the preparatory stage of glycolysis, the reactions occur in a specific order to convert glucose into two molecules of glyceraldehyde-3-phosphate. The correct order of reactions is as follows: 1. Hexokinase, which phosphorylates glucose to form glucose-6-phosphate. 2. Phosphoglucose isomerase, which converts glucose-6-phosphate into fructose-6-phosphate. 3. Phosphofructokinase, which phosphorylates fructose-6-phosphate to form fructose-1,6-bisphosphate. 4. Aldolase, which splits fructose-1,6-bisphosphate into two three-carbon molecules: glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. 5. Triose phosphate isomerase, which converts dihydroxyacetone phosphate into glyceraldehyde-3-phosphate. This order ensures that the intermediates are properly converted and prepared for the subsequent steps of glycolysis.

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  • 5. 

    Glycogen is:

    • The other term for Glycolysis

    • The storage carbohydrate in animals, insects and fungi.

    • The directly used energy source for all chemical reactions in the body.

    • None of the above

    Correct Answer
    A. The storage carbohydrate in animals, insects and fungi.
    Explanation
    Glycogen is the correct answer because it is indeed the storage carbohydrate in animals, insects, and fungi. It is a polysaccharide that serves as a reserve of glucose in these organisms. When energy is needed, glycogen is broken down into glucose molecules to provide fuel for various metabolic processes. Glycogen is stored in the liver and muscles and can be mobilized when energy demands increase, such as during exercise or fasting.

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  • 6. 

    Arange in right order Stage 2-

    • 6. Glyceraldehyde-3 Phosphate Dehydrogenase 7. Phosphoglycerate Kinase 8. Phosphoglycerate Mutase 9. Enolase 10. Pyruvate Kinase

    • 6. Pyruvate kinase 7. Enolase 8. Glyceraldehyde-3-phosphate Dehydrogenase 9. Phosphoglycerate Kinase 10. Phosphoglycerate Mutase

    • None of the above arrangements

    • All of the above

    Correct Answer
    A. 6. Glyceraldehyde-3 Phosphate Dehydrogenase 7. Phosphoglycerate Kinase 8. Phosphoglycerate Mutase 9. Enolase 10. Pyruvate Kinase
    Explanation
    The given answer arranges the enzymes involved in glycolysis in the correct order. Glyceraldehyde-3 Phosphate Dehydrogenase is the enzyme that catalyzes the conversion of glyceraldehyde-3 phosphate to 1,3-bisphosphoglycerate. Phosphoglycerate Kinase then catalyzes the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate. Phosphoglycerate Mutase converts 3-phosphoglycerate to 2-phosphoglycerate. Enolase catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. Finally, Pyruvate Kinase converts phosphoenolpyruvate to pyruvate.

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  • 7. 

    Ketoacidocis occurs during?

    • Protein synthesis disorders

    • Acoholism, starvation and diabetes

    • Paired brain metabolism

    • Amino acid synthesis

    Correct Answer
    A. Acoholism, starvation and diabetes
    Explanation
    Ketoacidosis occurs during alcoholism, starvation, and diabetes. Alcoholism can lead to ketoacidosis due to the excessive consumption of alcohol, which can disrupt normal metabolism and lead to the accumulation of ketone bodies. Starvation can also cause ketoacidosis as the body starts to break down fat for energy, resulting in an increase in ketone production. In diabetes, particularly when blood sugar levels are poorly controlled, the body may not be able to properly utilize glucose for energy, leading to the breakdown of fat and the production of ketones.

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  • 8. 

    Describe the process of Alcohol fermentation.

    • Glucose, (glycolysis)-->2Pyruvate + CO2 --> Ethyl alcohol

    • 2Pyruvate--> (glycolysis)--> Glucose--> Ethyl alcohol

    • Glycolysis-->2Pyruvate-->Ethyl alcohol

    • None of the above

    Correct Answer
    A. Glucose, (glycolysis)-->2Pyruvate + CO2 --> Ethyl alcohol
    Explanation
    The process of alcohol fermentation begins with glucose undergoing glycolysis, which results in the formation of 2 pyruvate molecules and the release of carbon dioxide. The 2 pyruvate molecules then undergo further reactions to produce ethyl alcohol. This is the correct answer as it accurately describes the sequential steps involved in alcohol fermentation, starting from glucose and ending with the production of ethyl alcohol.

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  • 9. 

    The Pyruvate Dehydrogenase Complex:

    • Pyruvate and COA and NAD is converted to Acetyl Co A + carbondioxide+ NADH and H+

    • Acetyl CO A + Co A + Pyruvate is converted to NAD+ and NADH + H+

    • NAD+ and Acetyl COA is converted to pyruvate dehydrogenase and NADH

    • None of the above

    Correct Answer
    A. Pyruvate and COA and NAD is converted to Acetyl Co A + carbondioxide+ NADH and H+
    Explanation
    The correct answer is that pyruvate and COA and NAD are converted to Acetyl Co A + carbondioxide+ NADH and H+. This is the correct answer because it accurately describes the conversion that occurs in the Pyruvate Dehydrogenase Complex. Pyruvate, CoA, and NAD are all substrates in this reaction, and they are converted into Acetyl Co A, carbon dioxide, NADH, and H+. This conversion is an important step in cellular respiration, as it links glycolysis with the citric acid cycle.

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  • 10. 

    What results in the formation of CO2 and the transfer of electrons producing NADH and FADH2?

    • Reducing potentials

    • The reduction of NAD

    • A series of oxidation reduction reactions

    • Production of ATP

    Correct Answer
    A. A series of oxidation reduction reactions
    Explanation
    A series of oxidation-reduction reactions results in the formation of CO2 and the transfer of electrons producing NADH and FADH2. During these reactions, molecules are oxidized, losing electrons, while other molecules are reduced, gaining those electrons. This transfer of electrons allows for the production of NADH and FADH2, which are important in cellular respiration. These reduced molecules can then be used to generate ATP, the cell's main energy source.

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  • 11. 

    How many enzymes does Glycogen Breakdown require?

    • 3 ( Glycogen phosphorylase) (Glycogen debranching enzyme) (Phosphoglucomutase)

    • 4 ( phosphoglucomutase, fructophosphomutase, glycophosphate, Glycogen enzyme)

    • 2. ( Phosphoglucose and Phosphoglucomutase)

    • None of the above

    Correct Answer
    A. 3 ( Glycogen phosphorylase) (Glycogen debranching enzyme) (Phosphoglucomutase)
    Explanation
    Glycogen breakdown requires three enzymes: Glycogen phosphorylase, Glycogen debranching enzyme, and Phosphoglucomutase. These enzymes work together to break down glycogen into glucose molecules, which can then be used as a source of energy by the body. Glycogen phosphorylase is responsible for breaking the glucose molecules off the glycogen chain, while the debranching enzyme helps remove branches from the glycogen structure. Phosphoglucomutase then converts glucose-1-phosphate to glucose-6-phosphate, which can enter the glycolysis pathway for further energy production.

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  • 12. 

    What are the stages of Glycolytic pathway?

    • Preparatory stage where glucose is phosphorylated, Payoff stage- where 2 ATP is converted to Pyruvate and 4 ATPs

    • Preparatory stage- where glycose is not phosphorylated but is used direct to cleave 2 molecules of glyceraldehyde, Payoff stage- Where 2 GAPs is converted to 6 ATPs and pyruvate

    • Preparatory stage- where glucose is phophorylated and cleaved. Payoff stage- 4 ATPs are converted to 2 GAPs

    • Payoff stage, Preparatory stage

    Correct Answer
    A. Preparatory stage where glucose is phosphorylated, Payoff stage- where 2 ATP is converted to Pyruvate and 4 ATPs
    Explanation
    The correct answer is the first option: Preparatory stage where glucose is phosphorylated, Payoff stage- where 2 ATP is converted to Pyruvate and 4 ATPs. In the preparatory stage of the glycolytic pathway, glucose is phosphorylated, making it more reactive and ready for further breakdown. In the payoff stage, the phosphorylated glucose is converted into pyruvate, producing a net gain of 2 ATP molecules and 4 ATP molecules through substrate-level phosphorylation. This explanation accurately describes the stages and processes involved in the glycolytic pathway.

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  • 13. 

    How does Glycolysis provide ATP during fermentation?

    • Conversion of phosphofructase kinase to NAD+ which is then used in maintaining glycolysis

    • Pyruvate is reduced by NADH, producing NAD+ which keeps glycolysis going

    • By the Cellular respiration process, where the byproducts are CO2 and H2O

    • None of the above

    Correct Answer
    A. Pyruvate is reduced by NADH, producing NAD+ which keeps glycolysis going
    Explanation
    During fermentation, glycolysis provides ATP by the process of pyruvate reduction. Pyruvate is reduced by NADH, which generates NAD+. This replenishes the NAD+ required for the continuation of glycolysis, allowing the production of ATP to continue. This process occurs in the absence of oxygen and is an important mechanism for ATP production in anaerobic conditions. The other options mentioned, such as the conversion of phosphofructase kinase to NAD+ or the byproducts of cellular respiration, are not directly related to how glycolysis provides ATP during fermentation.

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  • 14. 

    Which are the five coenzymes used in the PDH complex?

    • Three are prosethetic groups bond to their enzymes , ( TPP,Lipoamide,FAD) and Two are transiently associated with the complex ( Co A, NAD+/NADH

    • Three are transiently associated with the complex; NAD+/NADH, Lipoamide, CoA Two are prosthetic groups: FAD, TPP

    • TPP, NADH/NAD+ are prostethic groups and the lipoamide, CoA, FAD and TPP are associated with the complex

    • None of the above

    Correct Answer
    A. Three are prosethetic groups bond to their enzymes , ( TPP,Lipoamide,FAD) and Two are transiently associated with the complex ( Co A, NAD+/NADH
    Explanation
    The correct answer states that three coenzymes (TPP, Lipoamide, FAD) are prosthetic groups that are bonded to their enzymes in the PDH complex, while two coenzymes (CoA, NAD+/NADH) are transiently associated with the complex. This means that the three prosthetic groups are permanently attached to their respective enzymes and play a crucial role in the catalytic reactions of the complex, while the two transiently associated coenzymes bind and unbind from the complex as needed during the reaction.

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  • 15. 

    What is the byproduct of glycolysis?

    • Pyruvic acid, ATP and NADH

    • Ammonia and ATP

    • Lactate

    • LAD and ATP

    Correct Answer
    A. Pyruvic acid, ATP and NADH
    Explanation
    During glycolysis, glucose is broken down into pyruvate. Commencing with a single glucose molecule, glycolysis concludes with the production of two pyruvate (pyruvic acid) molecules, four ATP molecules, and two NADH molecules. Therefore, the ultimate outcome is the formation of pyruvic acid.

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  • 16. 

    What is the name of the group that makes it possible for muscles to work without oxygen supply for about 10 seconds?

    • Adrenaline phosphate

    • Phosphofructase kinase

    • Creatine phosphate

    • Hexo Kinase

    Correct Answer
    A. Creatine phosphate
    Explanation
    Creatine phosphate is the correct answer because it is a high-energy compound that can rapidly regenerate ATP (adenosine triphosphate), the molecule that provides energy for muscle contraction. During intense exercise, when oxygen supply is limited, creatine phosphate can be broken down to produce ATP, allowing muscles to continue working for a short period without oxygen. This process is important for activities that require short bursts of intense effort, such as sprinting or weightlifting.

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  • 17. 

    Describe the production of Ketone bodies:

    • Acetoacetate is converted to Acetoacetyl CoA and then 2 Acetyl CoA

    • Acetoacetate is converted to 2 Acetoacetyl CoA and then 4 Acetyl CoA

    • Acetoacetate is converted to 2 Acetoacetyl Co A and then 6 Acetyl Co A

    • None of the above

    Correct Answer
    A. Acetoacetate is converted to Acetoacetyl CoA and then 2 Acetyl CoA
    Explanation
    Acetoacetate is converted to Acetoacetyl CoA, which is then further converted to 2 Acetyl CoA molecules. This process is known as ketogenesis and occurs in the liver during periods of prolonged fasting or low carbohydrate intake. The Acetyl CoA molecules can then enter the citric acid cycle and be used as an energy source by the body. This is the correct answer because it accurately describes the production of ketone bodies.

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  • 18. 

    What is used to drive the phosphorylation of ADP to ATP?

    • Reducing potentials of enzymes and aminoacids

    • Reducing potentials of NADH and FADH2

    • Oxidising potentials of glucose and NAD

    • Oxidising potential of Fructose and NAD

    Correct Answer
    A. Reducing potentials of NADH and FADH2
    Explanation
    NADH and FADH2 are electron carriers that are produced during cellular respiration. These molecules have high reducing potentials, meaning they readily donate electrons to other molecules. In the electron transport chain, NADH and FADH2 transfer their electrons to a series of protein complexes, which creates a flow of electrons and generates energy. This energy is used to drive the phosphorylation of ADP to ATP, a process known as oxidative phosphorylation. Therefore, the reducing potentials of NADH and FADH2 play a crucial role in the production of ATP.

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  • 19. 

    The energy in Malate Dehydrogenase is:

    • Positive

    • Negative

    • Equal to the electropotential gradient

    • Both 1 and 2

    Correct Answer
    A. Positive
    Explanation
    The energy in Malate Dehydrogenase is positive because it catalyzes the conversion of malate to oxaloacetate by transferring a hydride ion from malate to NAD+, resulting in the formation of NADH. This transfer of electrons leads to a decrease in the free energy of the system, making it energetically favorable and therefore positive.

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  • 20. 

    Describe the processes in Cori cycle.

    • Gluconeogenisis in muscles and glycolysis in muscles where glucose is converted to pyruvate and lactate

    • Glycolysis in liver where glucose is converted to pyruvate and lactate. Glyconeogenesis in muscles.

    • Glyconeogenesis in liver were lactate is converted to pyruvate and then glucose.Glycolysis in muscles

    • Glycolysis in stomach where glucose is converted to pyruvate and lactate. Glyconeogenesis in muscles.

    Correct Answer
    A. Glyconeogenesis in liver were lactate is converted to pyruvate and then glucose.Glycolysis in muscles
    Explanation
    The Cori cycle is a metabolic pathway that describes the conversion of glucose to lactate in muscles and the subsequent conversion of lactate back to glucose in the liver. In this process, during intense exercise, muscles produce lactate through glycolysis as a result of the breakdown of glucose. Lactate is then transported to the liver, where it is converted back to pyruvate and then to glucose through a process called gluconeogenesis. This glucose is released into the bloodstream and can be used by other tissues for energy. Meanwhile, glycolysis continues in muscles to provide them with energy.

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  • 21. 

    Acetate is oxidised further in the

    • Electron Transport Chain

    • In UDPG

    • TCA cycle

    • All of the above

    Correct Answer
    A. TCA cycle
    Explanation
    The correct answer is TCA cycle. The TCA cycle, also known as the citric acid cycle or Krebs cycle, is a series of chemical reactions that occur in the mitochondria of cells. It is an important metabolic pathway that plays a central role in the oxidation of various molecules, including acetate. During the TCA cycle, acetate is further oxidized to produce energy in the form of ATP. Therefore, the TCA cycle is the correct answer as it is the pathway where acetate is oxidized further.

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  • 22. 

    How many coenzymes does the PDH Compex use?

    • 3

    • 4

    • 5

    • 6

    Correct Answer
    A. 5
    Explanation
    The PDH Complex uses 5 coenzymes. Coenzymes are molecules that assist enzymes in their function. In the case of the PDH Complex, these coenzymes help in the conversion of pyruvate into acetyl-CoA, which is an important step in cellular respiration. The 5 coenzymes used by the PDH Complex are thiamine pyrophosphate (TPP), lipoic acid, coenzyme A (CoA), NAD+, and FAD. Each of these coenzymes plays a specific role in the overall reaction, facilitating the transfer of electrons and the formation of acetyl-CoA.

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  • 23. 

    For every acetate entering the TCA cycle:

    • 5 molecules of ATP/ acetate is produced

    • 8 molecules of ATP/ acetate is produced

    • 10 molecules of ATP/ acetate is produced

    • 7 molecules of ATP/acetate is produced

    Correct Answer
    A. 10 molecules of ATP/ acetate is produced
    Explanation
    For every acetate molecule that enters the TCA (Tricarboxylic Acid) cycle, the net production of ATP (adenosine triphosphate) through oxidative phosphorylation is generally estimated to be about 10 molecules. This estimation includes the ATP generated directly during the TCA cycle and the subsequent electron transport chain.

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  • 24. 

    Under starvation conditions:

    • Muscle proteins can derive its energy from 80 precent of the ketone bodies

    • Brain adapts and can derive 80 percent of its energy from ketone bodies

    • Both of the above statements are false

    • Neither 1 nor 2

    Correct Answer
    A. Brain adapts and can derive 80 percent of its energy from ketone bodies
    Explanation
    During starvation conditions, the brain adapts and can derive 80 percent of its energy from ketone bodies. This is because when the body is deprived of glucose, it starts breaking down fats for energy production. As a result, ketone bodies are produced as an alternative fuel source, which the brain can utilize efficiently. This adaptation allows the brain to continue functioning even in the absence of glucose, ensuring its survival during periods of food scarcity.

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  • 25. 

    What drives the Citrate Synthase?

    • The hydrolysis of vitamin C

    • The hydrolysis of the thioacetate

    • The hydrolysis of the thioester

    • Hydrolysis of Hexo Kinase

    Correct Answer
    A. The hydrolysis of the thioester
    Explanation
    The correct answer is the hydrolysis of the thioester. Citrate Synthase is an enzyme involved in the citric acid cycle, which is a series of chemical reactions that produce energy in the form of ATP. The hydrolysis of the thioester is a crucial step in the reaction catalyzed by Citrate Synthase, as it allows the enzyme to bind with acetyl-CoA and oxaloacetate to form citrate. This reaction is essential for the proper functioning of the citric acid cycle and the production of ATP.

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  • 26. 

    Hypoketotic state?

    • Is not associated with the metabolic disordes but the disorder to not produce ketone bodies to be used as energy for the brain

    • Lipid metabolic disorders

    • The liver is producing too many ketone bodies

    • None of the above

    Correct Answer
    A. Lipid metabolic disorders
    Explanation
    The correct answer is lipid metabolic disorders. Hypoketotic state refers to a condition where the body is unable to produce sufficient ketone bodies for energy. This is commonly seen in lipid metabolic disorders, where there is a dysfunction in the metabolism of lipids, leading to a decrease in the production of ketone bodies. Therefore, the correct answer is lipid metabolic disorders.

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  • 27. 

    Ketone bodies are normally used as:

    • Energy source for the brain in peripheral tissued

    • Energy source in the Cardiac muscle and Renal cortex but not the brain.

    • Energy source in the production of bile and the proper functioning of kidneys.

    • Energy source for the heart

    Correct Answer
    A. Energy source in the Cardiac muscle and Renal cortex but not the brain.
    Explanation
    Ketone bodies are produced in the liver during periods of prolonged fasting or low carbohydrate intake. They serve as an alternative energy source when glucose is scarce. While the brain can utilize ketone bodies as an energy source during prolonged fasting, it primarily relies on glucose for energy. On the other hand, the cardiac muscle and renal cortex have a higher capacity to use ketone bodies as an energy source. Therefore, ketone bodies are used as an energy source in the cardiac muscle and renal cortex, but not the brain.

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