1.
Which anion evolves a gas with a fruity odor when treated with concentrated sulfuric acid and ethanol?
Correct Answer
B. CH3COO
Explanation
The anion CH3COO (acetate) releases a gas with a fruity odor when it is treated with concentrated sulfuric acid and ethanol. This reaction involves the formation of ethyl acetate, which is an ester commonly used in solvents and has a distinctive sweet, fruity smell similar to pears. The process is a classic example of esterification, where an acid (from the acetate ion) reacts with an alcohol (ethanol) in the presence of an acid catalyst (sulfuric acid) to form an ester and water. This reaction is not only important in chemical synthesis but is also used in flavorings and fragrances.
2.
Besides activated charcoal and tannic acid, what is the other component of the universal antidote?
Correct Answer
D. MgO
Explanation
Magnesium oxide (MgO) is the other component of the universal antidote, alongside activated charcoal and tannic acid. This combination is traditionally used to treat poisoning by absorbing toxins, neutralizing acids, and slowing the absorption of poisons in the stomach and intestines. Magnesium oxide acts as a fast-acting antacid, neutralizing stomach acids and creating a protective layer that can trap harmful substances, reducing their harmful effects and aiding in their removal from the body. This makes it a crucial part of the universal antidote formula, providing broad-spectrum efficacy against a range of ingested poisons.
3.
What is the chemical formula for calomel?
Correct Answer
A. Hg2Cl2
Explanation
Calomel, known chemically as mercury(I) chloride, has the formula Hg2Cl2. This compound consists of mercury and chlorine, where the mercury is in the +1 oxidation state, unusual because mercury typically exhibits a +2 oxidation state in most of its compounds. Calomel has been historically used in medicine, particularly as a diuretic and purgative, although its use has declined due to toxicity concerns. The unique formulation involving two mercury atoms bonded together, as reflected in its chemical formula, distinguishes it from mercury(II) chloride (HgCl2), which is significantly more toxic.
4.
What salt is contained in Bordeaux Mixture?
Correct Answer
A. Cupric sulfate
Explanation
Bordeaux Mixture, a well-known fungicide used in gardening and agriculture, contains cupric sulfate as its primary salt component. This blue-colored compound, also known as copper sulfate, is combined with lime (calcium hydroxide) and water to form the mixture. The copper in the Bordeaux Mixture acts as an effective fungicide, helping to prevent and control fungal diseases such as downy mildew and powdery mildew on plants. The addition of lime helps to regulate the pH of the mixture, ensuring that the copper remains effective over time and reduces the risk of copper toxicity to plants.
5.
Increases osmotic load of the GIT:
Correct Answer
C. Saline cathartic
Explanation
Saline cathartics are substances that increase the osmotic load of the gastrointestinal tract (GIT). When taken orally, they draw water into the intestines through osmosis, which softens the stool and promotes bowel movements. This increased osmotic load stimulates the movement of fluid into the intestines, resulting in increased water content in the stool and ultimately relieving constipation. Therefore, saline cathartics are the correct answer as they directly increase the osmotic load of the GIT.
6.
The following can cause a shift of equilibrium except:
Correct Answer
A. Catalyst
Explanation
A catalyst is not capable of causing a shift of equilibrium because it does not affect the position of the equilibrium. Instead, a catalyst speeds up the rate of the forward and reverse reactions equally, allowing the system to reach equilibrium faster but not altering the equilibrium concentrations of reactants and products. In contrast, changes in concentration, pressure, and temperature can affect the equilibrium position by altering the relative concentrations of reactants and products.
7.
What characteristic color does copper impart to a nonluminous flame?
Correct Answer
C. Green
Explanation
Copper, when exposed to a nonluminous flame, typically imparts a green color. This characteristic green flame test is a common method used in qualitative chemical analysis to identify the presence of copper ions in a compound. When copper heats up, it excites the electrons, which then release energy as they return to their original energy state. The energy released falls within the green portion of the visible light spectrum, hence producing the green flame. This distinct coloration is useful in laboratory settings for quickly indicating the presence of copper in a sample.
8.
What is the term for the index of protective power of colloids?
Correct Answer
A. Zigmondy
Explanation
The term "Zigmondy" refers to the index of protective power of colloids, named after Richard Adolf Zsigmondy, a chemist who made significant contributions to colloid chemistry. This index measures the ability of colloidal particles to stabilize against coagulation under various conditions. Zsigmondy's work in understanding the properties and behaviors of colloids has been pivotal in the development of various applications, including medicinal formulations and industrial processes where the stability of colloids is critical. The protective power index helps in evaluating the effectiveness of colloids in protecting dispersed phases from precipitating out.
9.
What is the densest element in the periodic table?
Correct Answer
D. Os
Explanation
Osmium (Os) is recognized as the densest naturally occurring element in the periodic table. It is a hard, brittle metal in the platinum group that has a bluish-white color. Osmium has a remarkably high density, about 22.59 grams per cubic centimeter, which makes it denser than any other element. This extreme density is due to its tightly packed atoms, which is characteristic of transition metals. Osmium is used in applications that require high density and durability, such as in fountain pen nib tipping material and in electrical contacts for its wear resistance.
10.
Which substance is a polyene antifungal antibiotic?
Correct Answer
B. Nystatin
Explanation
Nystatin is a polyene antifungal antibiotic that is particularly effective in treating fungal infections caused by Candida species, such as oral thrush and diaper rash. Polyenes work by binding to ergosterol, a key component of fungal cell membranes, thereby disrupting the membrane and causing cell contents to leak, which ultimately leads to the death of the fungal cell. Nystatin is not absorbed from the digestive tract and is thus mainly used for infections in the mouth or intestinal tract. It was discovered in 1950 and remains a critical tool in the management of fungal infections.
11.
What is methylated erythromycin known as?
Correct Answer
B. Clarithromycin
Explanation
Clarithromycin is known as a methylated erythromycin. It is a semi-synthetic derivative of erythromycin, an antibiotic produced by the bacterium Streptomyces erythreus. Clarithromycin belongs to the macrolide antibiotic class and is used to treat various bacterial infections including respiratory tract infections, skin infections, and more. The methylation of erythromycin to produce clarithromycin results in improved acid stability and tissue penetration compared to its precursor, erythromycin. This modification also helps in reducing certain side effects and enhances the effectiveness against a broader spectrum of bacteria by preventing the rapid degradation of the antibiotic in the acidic environment of the stomach.
12.
Streptomycin and other aminoglycoside antibiotics are:
Correct Answer
B. Ototoxic
Explanation
Streptomycin and other aminoglycoside antibiotics are known to cause ototoxicity, which refers to damage to the inner ear and resulting hearing loss or balance problems. This side effect occurs due to the drugs' toxic effect on the sensory cells in the cochlea, the part of the inner ear responsible for hearing. It is important to monitor patients receiving these antibiotics for any signs of hearing loss or balance issues.
13.
Plasil is:
Correct Answer
B. Metoclopromide
Explanation
Plasil is a medication used to treat nausea and vomiting. Metoclopromide is the correct answer because it is the generic name for Plasil. Acyclovir is an antiviral medication used to treat herpes infections. Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. Tranexamic acid is a medication used to prevent or control excessive bleeding.
14.
Which of the following penicillins is resistant to penicillinase?
Correct Answer
C. Oxacillin
Explanation
Oxacillin is resistant to penicillinase because it is a penicillinase-resistant penicillin. Penicillinase is an enzyme produced by some bacteria that can break down penicillin and render it ineffective. Oxacillin has a side chain that makes it less susceptible to the action of penicillinase, allowing it to maintain its antimicrobial activity. Ampicillin, carbenicillin, ticarcillin, and mezlocillin are not resistant to penicillinase and can be inactivated by the enzyme.
15.
What phenol is primarily obtained from clove oil?
Correct Answer
A. Eugenol
Explanation
Eugenol is a phenol primarily obtained from clove oil. It is the main component that gives clove oil its distinct aroma and flavor. Eugenol has various uses, both medically and in other industries. In dentistry, it is valued for its analgesic and antiseptic properties, often used in dental cement and to soothe pain from toothaches. Additionally, eugenol serves as a flavoring agent in some foods and perfumes. It also has antimicrobial properties, making it effective against a range of bacteria and fungi. This versatile compound is extracted from clove buds, leaves, and stems.
16.
Chemical Name of Green Vitriol:
Correct Answer
C. Ferrous Sulfate
Explanation
Ferrous sulfate is the correct answer because it is commonly known as green vitriol. It is a chemical compound that contains iron in the +2 oxidation state, hence the term "ferrous." It is used in various industries, including agriculture and medicine. Copper sulfate, magnesium sulfate, and sodium sulfate are different compounds and not referred to as green vitriol. Therefore, they are not the correct answers.
17.
Group of elements which is the considered to be the most reactive of all metallic elements:
Correct Answer
B. Group IA
Explanation
Group IA, also known as the alkali metals, is considered to be the most reactive group of metallic elements. This is because they have only one valence electron, which they readily lose to form a positive ion. This high reactivity is due to the low ionization energy and electronegativity of these elements. They react vigorously with water, oxygen, and halogens, and are stored under oil to prevent their reaction with air. Examples of Group IA elements include lithium, sodium, and potassium.
18.
Which substance is a glycopeptide antibiotic?
Correct Answer
D. Vancomycin
Explanation
Vancomycin is classified as a glycopeptide antibiotic. It is used primarily for the treatment of serious bacterial infections caused by gram-positive bacteria that are resistant to other antibiotics, notably MRSA (methicillin-resistant Staphylococcus aureus). Glycopeptide antibiotics like vancomycin work by inhibiting bacterial cell wall synthesis, which is crucial for bacterial growth and replication. They do this by binding to the amino acid sequences that are necessary for forming the cell wall structures, effectively disrupting the bacteria's ability to form a functional cell wall, leading to cell death. Vancomycin is often used as a drug of last resort when other antibiotics are ineffective.
19.
Superior to acyclovir in the treatment of herpes viruses in the CNS in neonates:
Correct Answer
C. Vidarabine
Explanation
Vidarabine is the correct answer because it is more effective than acyclovir in treating herpes viruses in the central nervous system (CNS) in neonates. Vidarabine is an antiviral medication that works by inhibiting the replication of the virus. It has been specifically approved for the treatment of herpes simplex encephalitis in neonates, making it a superior choice compared to acyclovir in this particular scenario.
20.
This is an effective antidote for the treatment of poisoning by copper:
Correct Answer
A. Penicillamine
Explanation
Penicillamine is an effective antidote for the treatment of copper poisoning. It works by binding to the excess copper in the body and forming a complex that can be excreted through urine. This helps to reduce the toxic effects of copper and restore normal copper levels in the body. Penicillamine is commonly used in cases of Wilson's disease, a genetic disorder that causes copper buildup in the body. It is also used in cases of acute copper poisoning.