1.
Select two types of connective tissue
Correct Answer(s)
A. Cartilage
B. Bone
Explanation
they both have living cells that secrete the extracellular matrix in which the cells are housed.
>extracelluar matrix
- Ground substance
- Intercellular protein fibers
Characteristics of the tissue depend on the extracellular matrix
ex: collagen; white, strong
2.
Divide to form the other bone cells
Correct Answer
A. Osteogenic cells
Explanation
Osteogenic cells: divide to form the other bone cells
Osteoblasts: lay down the extracellular matrix
Osteocytes: Live in the mature bone and maintain the extracellular matrix
Osteoclasts: Break down the extracellular matrix
3.
Lay down the extracellular matrix
Correct Answer
A. Osteoblasts
Explanation
Osteogenic cells: divide to form the other bone cells
Osteoblasts: lay down the extracellular matrix
Osteocytes: Live in the mature bone and maintain the extracellular matrix
Osteoclasts: Break down the extracellular matrix
4.
Live in the mature bone and maintain the extracellular matrix
Correct Answer
A. Osteocytes
Explanation
Osteogenic cells: divide to form the other bone cells
Osteoblasts: lay down the extracellular matrix
Osteocytes: Live in the mature bone and maintain the extracellular matrix
Osteoclasts: Break down the extracellular matrix
5.
Break down the extracellular matrix
Correct Answer
A. Break down the extracellular matrix
Break down the extracellular matrix
Break down the extracellular matrix
Osteoclasts
Explanation
Osteogenic cells: divide to form the other bone cells
Osteoblasts: lay down the extracellular matrix
Osteocytes: Live in the mature bone and maintain the extracellular matrix
Osteoclasts: Break down the extracellular matrix
6.
Ground substance of cartilage is a gel containing 65-80% _____
Correct Answer
A. Water
Explanation
Oxygen and food can diffuse through this gel.
Therefore, the tissue does not need blood vessels
7.
Which cartilage does contain very few fibers?
Correct Answer
A. Costal cartilages
Explanation
Hyaline cartilage : very few fibers ex: caostal cartilages that joint the ribs to the sternum and vertebrae.
Fibrocartilage: some elastin fibers ex: intervertebral disks, the symphysis pubs
Elastic cartilage: many elastin fibers ex: external ear, epiglottis, larynx
8.
Ground substance of bone contains crystals of _____
Correct Answer
A. Calcium salts
Explanation
These make the bone rigid
9.
Which does contain blood vessels?
Correct Answer
B. Bone
Explanation
the bone rigid block oxygen and food diffusin, so bone must contain blood vessles
10.
A lattice of tiny strus of bone, like a sponge
Correct Answer
A. Cancellous bone
Explanation
Compact bone: laid down in layers like an onion: outside
11.
Which is the 2nd stage of bone remodeling?
Correct Answer
B. Osteoclasts remove damaged areas of bone
Explanation
1. Osteoblasts and osteoclasts are formed when they needed to remodel bone.
2. Osteoclasts remove damaged areas of bone.
3. Osteoblasts come after them and replace the extracellular matrix.
12.
When is Parathyroid hormone released?
Correct Answer
A. Blood calcium levels decrease
Explanation
PTH acts to maintain serum levels of ionized calcium
13.
Sustained Paratyroid Hormone raises blood calcium levels from _____.
Correct Answer
D. All of the above
Explanation
PTH acts to maintain serum levels of ionized calcium; it increases the release of calcium and phosphae from bone, the conservation of calcium and elimination of phosphate by kidney, and the intestinal reabsorption of calcium through vitamin D
14.
How can you creat Vitamin D in skin cells?
Correct Answer
A. Influence of sunlight
Explanation
Exposure to sunlight is responsible for the creation of Vitamin D in skin cells. When the skin is exposed to sunlight, it triggers a reaction that converts a substance in the skin called 7-dehydrocholesterol into Vitamin D3. This inactive form of Vitamin D is then converted into its active form by the liver and kidneys. Therefore, the influence of sunlight is crucial for the production of Vitamin D in skin cells.
15.
When is Calcitonin released?
Correct Answer
A. Blood calcium is too high
Explanation
Calcitonin inhibits the release of calcium and phosphate, thereby serving to lower serum calcium levels.
16.
Select Calcitonin
Correct Answer(s)
A. Inhibits the rease of calcium from bone
B. Reduces osteoclast activity
C. Inhibits vitamin D activation in the kidney
D. Inhibits calcium reabsorption by the kidney
Explanation
Calcitonin is a hormone that is responsible for inhibiting the release of calcium from the bone. It also reduces the activity of osteoclasts, which are cells that break down bone tissue. Additionally, calcitonin inhibits the activation of vitamin D in the kidney, which is necessary for the absorption of calcium. Finally, it also inhibits the reabsorption of calcium by the kidney.
17.
Which born area does contain bone marrow?
Correct Answer
B. DiapHysis
Explanation
Epiphysis = end
Diaphysis = shaft
- contains bone marrow
red bone marrow: makes blood cells
yellow marrow; contains fat
Metaphysis = widening before the end of the bone
18.
Which bone marrow does make blood cells?
Correct Answer
A. Red marrow
Explanation
red bone marrow: makes blood cells
yellow marrow; contains fat
19.
Little mobility
Correct Answer
A. Synarthroses
Explanation
Diarthroses: highly mobile ex: shoulder
20.
Select clasification of type
Correct Answer(s)
G. Comminuted
H. Segmental
I. Butterfly
J. Impacted
Explanation
Transverse: ceused by simple angulatory forces
Oblique: unstable and may change position after reduction
Spiral: results from a twisting motion, or torque
Comminuted: has more than two pieces
Segmental:
Butterfly:
Impacted: when the fracture fragments are wedged together
Location: proximal, midshaft, or distal
The direction of fracture line (transverse, oblique, spiral)
Type (comminuted, segmental, butterfly, or impacted)
21.
Select classification of location
Correct Answer(s)
A. Proximal
B. Midshaft
C. Distal
Explanation
Transverse: ceused by simple angulatory forces
Oblique: unstable and may change position after reduction
Spiral: results from a twisting motion, or torque
Comminuted: has more than two pieces
Segmental:
Butterfly:
Impacted: when the fracture fragments are wedged together
Location: proximal, midshaft, or distal
The direction of fracture line (transverse, oblique, spiral)
Type (comminuted, segmental, butterfly, or impacted)
22.
The most common fractures are those resulting from _____.
Correct Answer
A. Sudden injury
Explanation
The most common fractures are those resulting from sudden injury. This means that fractures are most commonly caused by accidents or trauma that occur suddenly, such as falls, car accidents, or sports injuries. Fractures caused by sudden injury are more common than those caused by fatigue or pathologic conditions.
23.
Identify the steps in the treatment and recovery process of a fracture.
Correct Answer
A. Reduction
Explanation
Reduction is the first step in the treatment and recovery process of a fracture. It involves realigning the broken bones to their normal position. This can be done through manual manipulation or surgical intervention. Once the bones are properly aligned, the next step is immobilization. This is done by applying casts, splints, or other devices to keep the bones in place and prevent further movement. Immobilization helps in the healing process. Lastly, after the fracture has healed, the focus shifts to restoring function and rehabilitating the affected area. This may involve physical therapy, exercises, and other interventions to regain strength, flexibility, and mobility.
24.
Discuss the four steps of bone healing. Select 3rd step.
Correct Answer
C. Calcium salts deposited in new tissue
Explanation
1. Hematoma forms and fibirin network fills it
2. Cells grow along fibirin meshwork to form new tissue
3. Calcium salts deposited in new tissue
4. New tissue remodedled into normal shape
25.
Which is the most common primary malignat bone tumor?
Correct Answer
A. Osteosarcoma
Explanation
Osteosarcoma: begins in osteogenic cells of the bone and is the most common type of bone cancer
Ewing sarcoma: small round cell tumors of bone and soft tissue origin
Chondrosarcoma: its origin in the cartilaginous elements of bone
Metastases: multiple in occurrence, originating primarily from cancers of the breast, lung, and prostate
26.
Changes in organ function (organ damage, inflammation, and failure)
Correct Answer
A. Pathologic fracture
Explanation
Changes in organ function (organ damage, inflammation, and failure): pathologic fracture
Local effects of tumors (e.g., compression of nerves or veins, stretching of periosteum): pain and weakness
Nonspecific signs of tissue breakdown (e.g., protein wasting, bone breakdown): calcium release, hypercalcemia
27.
Local effects of tumors (e.g., compression of nerves or veins, stretching of periosteum):
Correct Answer
B. Pain and weakness
Explanation
Changes in organ function (organ damage, inflammation, and failure): pathologic fracture
Local effects of tumors (e.g., compression of nerves or veins, stretching of periosteum): pain and weakness
Nonspecific signs of tissue breakdown (e.g., protein wasting, bone breakdown): calcium release, hypercalcemia
28.
Nonspecific signs of tissue breakdown (e.g., protein wasting, bone breakdown)
Correct Answer
C. Calcium release, hypercalcemia
Explanation
Changes in organ function (organ damage, inflammation, and failure): pathologic fracture
Local effects of tumors (e.g., compression of nerves or veins, stretching of periosteum): pain and weakness
Nonspecific signs of tissue breakdown (e.g., protein wasting, bone breakdown): calcium release, hypercalcemia
29.
Select Rheumatoid Arthritis
Correct Answer(s)
A. Autoimmune disorder
B. Antibodies against IgG fragments
C. Cause inflamattion in the joint
D. Abnormal healing responses lay down granulation tissue (pannus)
Explanation
Rheumatoid Arthritis
-Autoimmune disorder
-Antibodies against IgG fragments
-Cause inflamattion in the joint
-Abnormal healing responses lay down granulation tissue (pannus)
Osteoarthritis Syndrome
-Degenerative joint disease
-Inflammation of the joints often secondary to physical damage
-Damaged joint cartilage tries to heal itself
--Creating osteophytes or sprus
-Cartilage contains more water, less collagen
--Cartilage becomes weak, rough, eroded
--No longer protects the ssurface of the bone
30.
Select Osteoarthritis Syndrome
Correct Answer(s)
E. Degenerative joint disease
F. Inflammation of the joints often secondary to pHysical damage
G. Damaged joint cartilage tries to heal itself
H. Creating osteopHytes or sprus
I. Cartilage contains more water, less collagen
J. Cartilage becomes weak, rough, eroded
K. No longer protects the ssurface of the bone
Explanation
Rheumatoid Arthritis
-Autoimmune disorder
-Antibodies against IgG fragments
-Cause inflamattion in the joint
-Abnormal healing responses lay down granulation tissue (pannus)
Osteoarthritis Syndrome
-Degenerative joint disease
-Inflammation of the joints often secondary to physical damage
-Damaged joint cartilage tries to heal itself
--Creating osteophytes or sprus
-Cartilage contains more water, less collagen
--Cartilage becomes weak, rough, eroded
--No longer protects the ssurface of the bone
31.
Select Systemic Lupus Erythematosus
Correct Answer(s)
A. Arthralgia
B. Skin lesions (butterfly rash)
C. GlomerulonepHritis
D. Pleuritis
E. Pericarditis
F. Atherosclerosis
G. CNS inflammations
Explanation
SLE can damage any tissue
-Arthralgia
-Skin lesions (butterfly rash)
-Glomerulonephritis
-Pleuritis
-Pericarditis
-Atherosclerosis
-CNS inflammations
32.
Where is the most common site of gout?
Correct Answer
A. Big toe
Explanation
Gout is a form of arthritis that occurs when there is a build-up of uric acid crystals in the joints. The most common site for gout to occur is in the big toe joint. This is because the big toe joint is often subjected to more stress and pressure, making it more susceptible to inflammation and the deposition of uric acid crystals. Additionally, the temperature of the big toe joint is slightly lower than other joints, which further promotes the formation of crystals. Therefore, the big toe is the most common site of gout.
33.
The pathogenesis of gout resides in an elevation of _____ levels.
Correct Answer
A. Serum uric acid
Explanation
Gout is a form of arthritis caused by the buildup of uric acid crystals in the joints. The pathogenesis, or development, of gout is linked to elevated levels of serum uric acid. When there is an excess of uric acid in the blood, it can form crystals in the joints, leading to inflammation and pain. Therefore, maintaining normal levels of serum uric acid is crucial in preventing and managing gout.
34.
"bone buiding" cells
Correct Answer
A. Osteoblasts
Explanation
Osteoclasts- "bone breaking" cells
35.
"bone breaking" cells
Correct Answer
B. Osteoclasts
Explanation
Osteoclasts are cells responsible for breaking down bone tissue during the process of bone remodeling and growth. They play a crucial role in maintaining bone density and shape by removing old or damaged bone tissue. This process allows for the continual renewal and repair of bone throughout life. Osteoclasts are vital for maintaining bone health and are regulated by various hormones and signaling molecules in the body.
36.
Defective synthesis of connective tissue, including bone matrix
Correct Answer
A. Osteogenesis imperfect
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs
37.
A generalized bone condition in which there is inadequate mineralization of bone
Correct Answer
A. Osteomalacia
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs
38.
An acute or chronic infection of the bone and marrow
Correct Answer
A. Osteomyelitis
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs
39.
Decreased bone density
Correct Answer
A. Osteopenia
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs
40.
Decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Correct Answer
A. Osteoporosis
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs
41.
Regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Correct Answer
A. Paget disease
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs
42.
Vitamin D deficiency, inadequate calcium absorption from diet
Correct Answer
A. Rickets
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs
43.
A lateral curvature of the spine
Correct Answer
A. Scoliosis
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs
44.
Collagen deposits in skin and internal organs
Correct Answer
A. Systemic sclerosis
Explanation
osteogenesis imperfect: defective synthesis of connective tissue, including bone matrix
osteomalacia: a generalized bone condition in which there is inadequate mineralization of bone
osteomyelitis: an acute or chronic infection of the bone and marrow
osteopenia: decreased bone density
osteoporosis: decreased bone mass/density, decreased cancellous (spongy) bone strength, bone matrix and mineralization is decreased
Paget disease: regions of excessive bone turnover, new bone is disorganized, deformation and fracture common
Rickets: vitamin D deficiency, inadequate calcium absorption from diet
scoliosis: a lateral curvature of the spine
systemic sclerosis: collagen deposits in skin and internal organs