1.
Which have precautions of prolonged hypoglycemia?
Correct Answer(s)
A. Amaryl
C. Glipiride
D. Glyburide
Explanation
Amaryl, Glipiride, and Glyburide are all medications used to treat diabetes by lowering blood sugar levels. Prolonged hypoglycemia, or low blood sugar, is a potential side effect of these medications. Therefore, it is important for patients taking these drugs to be aware of the symptoms of hypoglycemia and take precautions to prevent it, such as regularly monitoring blood sugar levels and having a source of fast-acting carbohydrates on hand in case of an episode.
2.
When taking metformin, precautions are
Correct Answer(s)
A. Elevated creatine
B. Dehydration
C. High risk of lactic acidosis
D. Iodine dye tests
Explanation
When taking metformin, it is important to take precautions such as monitoring for elevated creatinine levels, as metformin can potentially cause kidney damage. Dehydration is also a concern because metformin can increase the risk of lactic acidosis, a serious condition that can occur when there is a buildup of lactic acid in the body. Additionally, metformin can interfere with iodine dye tests, so it is important to inform healthcare providers about the medication before undergoing such tests.
3.
There is cardiac risk with insulin and
Correct Answer
B. Avandia
Explanation
Avandia is a drug that belongs to a class called thiazolidinediones and is used to treat type 2 diabetes. However, it has been associated with an increased risk of cardiovascular events such as heart attacks and strokes. Therefore, there is a cardiac risk with Avandia.
4.
Glyburide is classified under
Correct Answer
D. Sulfonylureas
Explanation
Glyburide is classified under sulfonylureas because it belongs to this class of drugs that are commonly used to treat type 2 diabetes. Sulfonylureas work by stimulating the pancreas to produce more insulin, which helps lower blood sugar levels. Glyburide specifically acts by increasing the release of insulin from the beta cells in the pancreas. This classification is important for healthcare professionals to understand the mechanism of action and potential side effects of glyburide when prescribing it to patients with diabetes.
5.
Fluid retention, elevated liver enzymes are associated with which drugs?
Correct Answer
A. Thiazolidinediones
Explanation
Thiazolidinediones are a class of drugs used to treat type 2 diabetes. They work by increasing the body's sensitivity to insulin. However, they can also cause fluid retention and elevated liver enzymes as side effects. This is because thiazolidinediones can affect the kidneys' ability to regulate fluid balance and can also cause inflammation in the liver. Therefore, fluid retention and elevated liver enzymes are associated with thiazolidinediones.
6.
Exenatide (Byetta) is new therapy for type 2 DM called
Correct Answer
A. Incretin mimetics
Explanation
Exenatide (Byetta) is classified as an incretin mimetic, which is a new therapy for type 2 diabetes mellitus (DM). Incretin mimetics work by mimicking the action of incretin hormones, such as glucagon-like peptide-1 (GLP-1), which are naturally produced in the body to regulate blood sugar levels. Byetta helps to lower blood sugar levels by increasing insulin secretion, slowing down gastric emptying, and reducing glucagon secretion. It is not classified as alpha g, biguanides, or sulfonylureas, which are other types of medications used to treat type 2 DM.
7.
Fatty liver is associated with Type 1 DM.
Correct Answer
B. False
Explanation
Type 2
8.
Which medication is injected SQ BID within an hour before the two main meals?
Correct Answer
C. Exenatide (byetta)
Explanation
Exenatide (Byetta) is the correct answer because it is a medication that is injected subcutaneously (SQ) twice a day (BID) within an hour before the two main meals. Januvia, metformin, and liraglutide (Victoza) are not administered in the same way or at the same frequency as Exenatide (Byetta).
9.
This incretin mimetic reduces the liver fat content.
Correct Answer
D. Exenatide
Explanation
Exenatide is an incretin mimetic medication that is used to treat type 2 diabetes. It works by mimicking the action of the hormone incretin, which helps to regulate blood sugar levels. One of the effects of exenatide is that it can reduce the fat content in the liver. This is beneficial for individuals with type 2 diabetes, as excess fat in the liver can contribute to insulin resistance and poor blood sugar control. Therefore, exenatide is the correct answer as it specifically targets and reduces liver fat content.
10.
This medication is injected SQ daily for a week then slowly the dose is increased to obtain glycemic control.
Correct Answer
A. Liraglutide (Victoza)
Explanation
Liraglutide (Victoza) is the correct answer because it is a medication that is injected subcutaneously (SQ) on a daily basis. It is used to control blood sugar levels in patients with diabetes. The dosage of liraglutide is initially started at a low level and then gradually increased to achieve glycemic control. Exenatide (Byetta) is another medication that is also injected SQ, but it does not mention the gradual dose increase. Janumet and metformin are oral medications and not administered via injection.
11.
Victoza has a risk of?
Correct Answer(s)
A. Thyroid c cell tumors
B. Acute pacreatitis
Explanation
Victoza, a medication used to treat diabetes, has been associated with an increased risk of thyroid C cell tumors and acute pancreatitis. These are potential side effects that individuals taking Victoza should be aware of. Hyperglycemia, high blood sugar levels, is a symptom of diabetes and not a risk associated with Victoza. While death is a possible outcome in severe cases of certain medical conditions, it is not specifically linked to Victoza use.
12.
Select all incretin mimetics
Correct Answer(s)
A. Byetta
B. Januvia
C. Victoza
D. Onglyza
Explanation
The correct answer includes the medications Byetta, Januvia, Victoza, and Onglyza. These drugs are all classified as incretin mimetics, which means they mimic the action of incretin hormones in the body. Incretin hormones help to regulate blood sugar levels by increasing insulin secretion and decreasing glucagon production. Byetta, Januvia, Victoza, and Onglyza are commonly used in the treatment of type 2 diabetes to help control blood sugar levels and improve glycemic control.
13.
The nurse knows that oral hypoglycemic agents.
Correct Answer(s)
A. Decrease hepatic glucose production
B. Are only for type 2
C. Increase hepatic insulin sensitivity
D. Stimulate the islet cell to secrete more insulin
Explanation
Oral hypoglycemic agents are medications that are used to treat type 2 diabetes. They work by decreasing hepatic glucose production, which helps to lower blood sugar levels. These medications are not used for type 1 diabetes, as they rely on the body's ability to produce insulin. Additionally, oral hypoglycemic agents can also increase hepatic insulin sensitivity, making the body more responsive to the insulin that is produced. They do not directly stimulate the islet cells to secrete more insulin.
14.
Prolonged hypoglycemia is associated with sulfonylureas?
Correct Answer
A. True
Explanation
Prolonged hypoglycemia is indeed associated with sulfonylureas. Sulfonylureas are a class of medications commonly used to treat type 2 diabetes. They work by stimulating the release of insulin from the pancreas, which helps to lower blood sugar levels. However, one of the potential side effects of sulfonylureas is hypoglycemia, which occurs when blood sugar levels drop too low. If hypoglycemia is not promptly treated or if it occurs frequently, it can become prolonged and lead to serious complications. Therefore, it is important for individuals taking sulfonylureas to monitor their blood sugar levels closely and seek medical attention if hypoglycemia occurs.
15.
This type of OHA increases insulin secretion as well as increases insulin sensitivity at receptor sites.
Correct Answer
A. Sulfonylureas
Explanation
Sulfonylureas are a type of oral hypoglycemic agent (OHA) that increase insulin secretion from the pancreas and also improve insulin sensitivity at receptor sites in the body. This means that sulfonylureas help to stimulate the release of insulin and enhance the body's ability to use insulin effectively, resulting in lower blood sugar levels. Therefore, sulfonylureas are an effective treatment option for individuals with type 2 diabetes who need to increase insulin production and improve insulin sensitivity.
16.
Which are classified as sulfonylureas?
Correct Answer(s)
A. Diabenese
B. Tolinase
C. Orinase
E. Glyburide
F. Glipizide
17.
This is most commonly used for kids with type 2?
Correct Answer
D. Metfomin
Explanation
Metformin is the most commonly used medication for children with type 2 diabetes. It is an oral medication that helps to control blood sugar levels by improving insulin sensitivity and reducing the amount of glucose produced by the liver. Metformin is often prescribed in combination with lifestyle changes such as healthy eating and regular exercise. It is considered safe and effective for children and is recommended as the first-line treatment for type 2 diabetes in this age group.
18.
Miglitol and acarbose are known as what?
Correct Answer
D. AlpHa glucosidase inhibitors
Explanation
Miglitol and acarbose are known as alpha glucosidase inhibitors. These drugs work by slowing down the digestion and absorption of carbohydrates in the intestines, thereby reducing the rise in blood sugar levels after a meal. By inhibiting the enzyme alpha glucosidase, which is responsible for breaking down carbohydrates into glucose, these medications help to control blood sugar levels in individuals with diabetes.
19.
This should not be taken with dairy due to lactic acidosis.
Correct Answer
C. Metfomin
Explanation
Metformin is the correct answer because it should not be taken with dairy due to the risk of lactic acidosis. Lactic acidosis is a rare but serious side effect that can occur when there is a buildup of lactic acid in the body. Dairy products can increase the risk of lactic acidosis when taken with metformin. Therefore, it is important to avoid consuming dairy while taking this medication.
20.
Which med is classified as a biguanide?
Correct Answer
A. Metformin
Explanation
Metformin is classified as a biguanide because it belongs to the biguanide class of medications. Biguanides are a type of oral antidiabetic medication that helps to lower blood sugar levels by reducing the amount of glucose produced by the liver and improving the body's response to insulin. Metformin is commonly prescribed to treat type 2 diabetes and is known for its effectiveness in controlling blood sugar levels and reducing the risk of complications associated with diabetes.
21.
If the meal is skipped the nurse knows to also skip which OHA?
Correct Answer
C. Prandin
Explanation
If a meal is skipped, it means that the patient is not consuming any food. Prandin is an oral hypoglycemic agent (OHA) that is taken with meals to help control blood sugar levels. Since there is no meal being consumed, it would be appropriate for the nurse to skip administering Prandin in this situation. Janumet, Januvia, and metformin are other OHAs that are not affected by meal consumption and can still be administered even if a meal is skipped.
22.
The nurse knows that biguanides
Correct Answer(s)
A. Decrease hepatic glucose production
B. Lowers FBS
C. Decreases intestinal absorption of glucose
D. Enhances tissue response to absorption
E. Increases hepatic insulin sensitivity
Explanation
Biguanides, such as metformin, are a class of medications used to treat type 2 diabetes. They work by decreasing the production of glucose in the liver, which helps to lower fasting blood sugar levels. Additionally, biguanides can also decrease the absorption of glucose from the intestines and enhance the body's response to insulin, leading to increased insulin sensitivity. Therefore, all of the statements in the answer are correct and explain the effects of biguanides on glucose metabolism.
23.
Acarbose is not widely used due to the flatulence it causes.
Correct Answer
A. True
Explanation
Acarbose is a medication used to treat type 2 diabetes by slowing down the digestion of carbohydrates in the body. However, one of the common side effects of acarbose is flatulence, which is the excessive production of gas in the digestive system. This can cause discomfort and embarrassment for patients, leading to reduced compliance and limited use of acarbose. Therefore, it is true that acarbose is not widely used due to the flatulence it causes.
24.
This must be given with meals to boost insulin response to each meal.
Correct Answer
A. Meglitinides
Explanation
Meglitinides are a class of oral medications used to treat type 2 diabetes. They work by stimulating the release of insulin from the pancreas, which helps to lower blood sugar levels. Taking meglitinides with meals helps to boost the insulin response to each meal, as they are designed to be taken shortly before eating. This timing ensures that the medication is active when the body needs it most, during the digestion and absorption of food. By enhancing the insulin response, meglitinides help to control blood sugar levels and improve overall glycemic control in individuals with diabetes.
25.
Meglitinides' site of action is the muscle.
Correct Answer
B. False
Explanation
Pancreas
26.
Which are most likely to cause weight loss?
Correct Answer(s)
A. Biguanide
C. AlpHa g inhibitors
Explanation
Biguanides and alpha g inhibitors are most likely to cause weight loss. Biguanides, such as metformin, work by reducing glucose production in the liver and improving insulin sensitivity, which can lead to weight loss. Alpha g inhibitors, such as acarbose, delay the absorption of carbohydrates in the intestine, resulting in lower post-meal blood sugar levels and potential weight loss. Incretin hormones, such as GLP-1, actually promote weight loss, but the given answer does not include any specific incretin. Glucagon, on the other hand, is a hormone that increases blood sugar levels and is not likely to cause weight loss.
27.
Which meds are classified as meglitinides?
Correct Answer(s)
A. Prandin
B. Starlix
C. Repaglinide
D. Nateglinide
Explanation
The medications Prandin, Starlix, Repaglinide, and Nateglinide are classified as meglitinides.
28.
Which OHA delays carbohydrate absorption from the small intestine?
Correct Answer
B. AlpHa glucosidase
Explanation
Alpha glucosidase delays carbohydrate absorption from the small intestine. Alpha glucosidase is an enzyme that breaks down complex carbohydrates into simple sugars. By inhibiting this enzyme, the absorption of carbohydrates is slowed down, leading to a slower rise in blood sugar levels. This delay in carbohydrate absorption can be beneficial for individuals with conditions such as diabetes, as it helps to control blood sugar levels.
29.
This works in muscle and increases insulin sensitivity at insulin receptor sites.
Correct Answer
D. Thiazolidinediones
Explanation
Thiazolidinediones work in muscle and increase insulin sensitivity at insulin receptor sites. They are a class of drugs used to treat type 2 diabetes by improving the body's response to insulin. By enhancing insulin sensitivity, thiazolidinediones help the muscles to better utilize glucose, leading to better blood sugar control. This class of drugs is often prescribed in combination with other diabetes medications to achieve optimal glycemic control.
30.
There is an increased number of severe cardiac events associated with
Correct Answer
A. Thiazolidinediones
Explanation
Thiazolidinediones are a class of medications used to treat type 2 diabetes. However, they have been associated with an increased risk of severe cardiac events, such as heart attacks and heart failure. This may be due to their mechanism of action, which can cause fluid retention and lead to cardiovascular complications. Therefore, it is important to carefully consider the risks and benefits of using thiazolidinediones in patients with diabetes and cardiovascular disease.
31.
These have less hypoglycemia and less weight gain than other OHA.
Correct Answer
A. Incretin based therapy
Explanation
Incretin-based therapy refers to a type of medication used to treat diabetes that mimics the action of the incretin hormones in the body. These medications work by stimulating the release of insulin and reducing the production of glucagon, resulting in lower blood sugar levels. Compared to other oral hypoglycemic agents (OHA), incretin-based therapy has been found to have less risk of causing hypoglycemia (low blood sugar) and less weight gain. This makes it a favorable option for individuals with diabetes who are concerned about these potential side effects.
32.
Janumet is a combo of?
Correct Answer(s)
A. Sitagliptan
C. Metformin
Explanation
Janumet is a combination medication that contains sitagliptan and metformin. Sitagliptan is a medication used to treat type 2 diabetes by increasing the levels of incretin hormones in the body, which helps to control blood sugar levels. Metformin is another medication used to treat type 2 diabetes by improving insulin sensitivity and reducing the production of glucose in the liver. Therefore, Janumet combines the effects of both sitagliptan and metformin to provide better control of blood sugar levels in patients with type 2 diabetes.
33.
Which are Thiazolidinediones?
Correct Answer(s)
A. Rosiglitizone
B. Avandia
C. Pioglitizone
D. Actos
Explanation
Thiazolidinediones are a class of medications used to treat type 2 diabetes. Rosiglitazone (Avandia), pioglitazone (Actos), and Avandia are all examples of thiazolidinediones. These medications work by increasing the body's sensitivity to insulin, which helps to lower blood sugar levels. They are typically prescribed in combination with diet and exercise to help control blood sugar in patients with diabetes.
34.
Avandia takes 6-14 weeks to see effects.
Correct Answer
A. True
Explanation
The statement is true because Avandia is a medication used to treat diabetes, specifically type 2 diabetes. It belongs to a class of drugs called thiazolidinediones, which work by increasing the body's sensitivity to insulin. It typically takes several weeks for Avandia to start showing its full effects in controlling blood sugar levels. Therefore, it is accurate to say that it takes 6-14 weeks to see the effects of Avandia.