Pharmacology Quiz: Respiratory And Gastrointestinal Medications!
Medications are put in place to either ease a patient’s pain or to revert them to health. Being that you are a pharmacology student, the one thing that you should do is ensure you know which types of drugs to prescribe and when. Take up the quiz below and get to see how much you know about respiratory and gastrointestinal medication.
- 1.
What drug has a mode of action that weakly inhibits cylooxygenase?
- A.
Aspirin
- B.
Acetaminophen
- C.
Ibuprophen
- D.
Naproxen
Correct Answer
B. AcetaminopHenExplanation
Acetaminophen weakly inhibits cylooxygenase, which is an enzyme involved in the production of prostaglandins, substances that cause inflammation and pain. By inhibiting this enzyme, acetaminophen reduces the production of prostaglandins, thereby providing relief from pain and reducing fever. Aspirin, ibuprofen, and naproxen also inhibit cylooxygenase, but they do so more strongly compared to acetaminophen.Rate this question:
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- 2.
An NSAID that does not inhibit COX in the GI mucosa
- A.
Aspirin
- B.
Acetaminophen
- C.
Nalbumetone (Relafin)
- D.
Ibuprofen
Correct Answer
C. Nalbumetone (Relafin)Explanation
Nalbumetone (Relafin) is the correct answer because it is an NSAID that does not inhibit COX in the GI mucosa. COX (cyclooxygenase) is an enzyme responsible for the production of prostaglandins, which play a role in inflammation and pain. Traditional NSAIDs like aspirin and ibuprofen inhibit both COX-1 and COX-2, which can lead to gastrointestinal side effects such as stomach ulcers. Acetaminophen, although it has analgesic properties, is not considered an NSAID as it does not have anti-inflammatory effects. Nalbumetone (Relafin), on the other hand, selectively inhibits COX-2, making it less likely to cause GI mucosa inhibition and therefore a better option for patients who are at risk for gastrointestinal complications.Rate this question:
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- 3.
Action of traditional NSAID's
- A.
Inhibit COX-1
- B.
Inhibit COX-2
- C.
Do not inhibit COX-1 or COX-2
- D.
Both A and B
Correct Answer
D. Both A and BExplanation
Traditional NSAIDs inhibit both COX-1 and COX-2 enzymes. COX-1 is responsible for producing prostaglandins that protect the stomach lining and maintain kidney function, while COX-2 is involved in inflammation and pain. By inhibiting both enzymes, traditional NSAIDs provide pain relief and reduce inflammation but also have potential side effects such as stomach ulcers and kidney problems. Therefore, the correct answer is "Both A and B" because traditional NSAIDs inhibit both COX-1 and COX-2.Rate this question:
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- 4.
Gastrin acts in the GI tract to increase HCl by
- A.
Binding to CCK2 (cholecystekinin2) receptors to activate protein kinases to secrete H+ ions
- B.
Causing vasodilation and increased release of HCL from the islet cells
- C.
Inhibiting platelet aggregation whereby decreasing competition for H+ binding sites
- D.
Binding with H+ ions to create viscous coating of epithelial lining of the stomach
Correct Answer
A. Binding to CCK2 (cholecystekinin2) receptors to activate protein kinases to secrete H+ ionsExplanation
Gastrin acts in the GI tract to increase HCl by binding to CCK2 receptors. When gastrin binds to these receptors, it activates protein kinases, which in turn stimulate the secretion of H+ ions. This leads to an increase in the production of hydrochloric acid in the stomach.Rate this question:
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- 5.
60-80% of gastric ulcers are healed with treatment within
- A.
1-2 days
- B.
1-2 weeks
- C.
5-7 days
- D.
6-8 weeks
Correct Answer
D. 6-8 weeksExplanation
Gastric ulcers typically take a longer time to heal compared to other types of ulcers. The answer "6-8 weeks" is the most accurate because it aligns with the general healing timeline for gastric ulcers. This extended healing period is due to the fact that the stomach is constantly producing acid, which can delay the healing process. Additionally, treatment for gastric ulcers often involves medications that need to be taken for several weeks to reduce acid production and allow the ulcer to heal.Rate this question:
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- 6.
All of the following are effects of PGI-2 except:
- A.
Vasodilation
- B.
Platelet aggregation
- C.
Gastric cytoprotection
- D.
Pain sensitization
Correct Answer
B. Platelet aggregationExplanation
inhibits platelet aggregationRate this question:
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- 7.
All of the following are non-pharmacologic treatments of ulcers except:
- A.
Reducing stress
- B.
Avoiding aggrevating foods
- C.
Quit smoking
- D.
A 4 oz glass of red wine 3x/week
Correct Answer
D. A 4 oz glass of red wine 3x/weekExplanation
This answer is correct because all of the other options listed are non-pharmacologic treatments for ulcers. Reducing stress, avoiding aggravating foods, and quitting smoking are all lifestyle changes that can help prevent or alleviate ulcers. However, drinking a 4 oz glass of red wine 3 times a week is not a recognized non-pharmacologic treatment for ulcers.Rate this question:
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- 8.
Which of the following disease states decreases the metabolism of Theophylline?
- A.
Pancreatic cancer
- B.
CHF
- C.
Wilm's tumor
- D.
HTN
Correct Answer
B. CHFExplanation
CHF (Congestive Heart Failure) decreases the metabolism of Theophylline. CHF is a condition where the heart is unable to pump enough blood to meet the body's needs. This can lead to reduced blood flow to the liver, which is responsible for metabolizing drugs like Theophylline. As a result, the metabolism of Theophylline is decreased in patients with CHF, leading to higher levels of the drug in the body.Rate this question:
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- 9.
All of the following are ways that smoking adversely affects the GI tract except:
- A.
Increases gastrin production
- B.
Decreases blood flow
- C.
Decreases healing
- D.
Decreases HCO3 production
Correct Answer
A. Increases gastrin productionExplanation
Smoking adversely affects the GI tract in several ways, including decreasing blood flow, decreasing healing, and decreasing HCO3 production. However, it does not increase gastrin production. Gastrin is a hormone that stimulates the release of gastric acid in the stomach, and smoking does not have a direct effect on its production. Therefore, the correct answer is "increases gastrin production."Rate this question:
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- 10.
All of the following are true of Acetaminophen except
- A.
Weakly inhibits cylcooxygenase
- B.
Metabolized in the liver via glucoronidation
- C.
Analgesic, antipyretic and anit-inflammatory effects
- D.
Interacts with Coumadin
Correct Answer
C. Analgesic, antipyretic and anit-inflammatory effectsExplanation
no anti-inflammatory effectRate this question:
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- 11.
Allof the following are true of aspirin except
- A.
High albumin binding
- B.
May decrease effects of ACE inhibitors
- C.
Reversibly inhibits thromboxane
- D.
Absorption is decreased with higher pH's
Correct Answer
C. Reversibly inhibits thromboxaneExplanation
irreversibly inhibits thromboxaneRate this question:
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- 12.
Which of the following has the risk of Reye's syndrome if given when virus or varicella is present?
- A.
Aspirin
- B.
Acetaminophen
- C.
Diphenhydramine (Benadryl)
- D.
Warfarin
Correct Answer
A. AspirinExplanation
Aspirin has the risk of Reye's syndrome if given when a virus or varicella is present. Reye's syndrome is a rare but serious condition that primarily affects children and teenagers recovering from a viral infection, such as the flu or chickenpox. The use of aspirin during these infections has been linked to an increased risk of developing Reye's syndrome, which can cause liver and brain damage. Therefore, it is important to avoid giving aspirin to individuals with viral infections, especially children and teenagers, and instead use alternatives such as acetaminophen for pain relief and fever reduction.Rate this question:
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- 13.
All of the following are properties of COX-1 except
- A.
Present in low amounts in kidney, platelets and GI tract
- B.
Involved in thromboxane synthesis
- C.
Induced by cytokines
- D.
Renal vasodialtion
Correct Answer
C. Induced by cytokinesExplanation
COX-1 is an enzyme that is present in low amounts in the kidney, platelets, and GI tract. It is involved in the synthesis of thromboxane, which promotes platelet aggregation and vasoconstriction. However, COX-1 is not induced by cytokines. Cytokines are signaling molecules that regulate inflammation and immune responses, and they do not have a direct effect on COX-1 expression or activity. Therefore, the correct answer is that COX-1 is not induced by cytokines.Rate this question:
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- 14.
All of the following are true of NSAID's except:
- A.
Provide analgesia at 50% of the anti-inflammatory dose
- B.
Reversibly inhibit the COX system
- C.
Are typically only well absorbed in the duodenem
- D.
Are highly plasma-protein binding
Correct Answer
C. Are typically only well absorbed in the duodenemExplanation
NSAIDs (nonsteroidal anti-inflammatory drugs) are a class of medications that provide analgesia (pain relief) and inhibit the COX system, which is responsible for inflammation. They are known to be highly plasma-protein binding, meaning they attach to proteins in the blood. However, they are not typically only well absorbed in the duodenum, which is the first part of the small intestine. NSAIDs can be absorbed throughout the gastrointestinal tract.Rate this question:
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- 15.
Which of the following is NOT classified as an NSAID?
- A.
Bropheneramine (Veltane)
- B.
Indomethacin (Indocin)
- C.
Naproxen
- D.
Fenamic acid
Correct Answer
A. BropHeneramine (Veltane)Explanation
Bropheneramine (Veltane) is not classified as an NSAID because it is an antihistamine and decongestant medication used to relieve symptoms of allergies and nasal congestion. NSAIDs (nonsteroidal anti-inflammatory drugs) are a class of medications that primarily reduce inflammation, relieve pain, and reduce fever. Indomethacin, Naproxen, and Fenamic acid are all examples of NSAIDs commonly used for their anti-inflammatory and analgesic properties.Rate this question:
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- 16.
Which of the following is a controlled substance antitussive?
- A.
Dextromethorophan
- B.
Hydrocodone
- C.
Celecoxib (Celebrex)
- D.
Meloxicam (Mobic)
Correct Answer
B. HydrocodoneExplanation
Hydrocodone is a controlled substance antitussive because it is a narcotic cough suppressant. It works by binding to opioid receptors in the brain and spinal cord, reducing the cough reflex. This medication is commonly used to treat cough associated with conditions such as the common cold, bronchitis, or respiratory infections. Due to its potential for abuse and addiction, hydrocodone is classified as a controlled substance and requires a prescription from a healthcare professional. Dextromethorphan, on the other hand, is also an antitussive but is not a controlled substance. Celecoxib and meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) used for pain and inflammation, but they are not antitussives.Rate this question:
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- 17.
A drug that does not have decongestant properties is
- A.
Pseudoephedrine
- B.
Oxymetazoline
- C.
Tetrahydrazoline
- D.
Desloratadine (Clarinex)
Correct Answer
D. Desloratadine (Clarinex)Explanation
Desloratadine (Clarinex) is the correct answer because it is an antihistamine drug used to relieve allergy symptoms such as sneezing, runny nose, and itchy or watery eyes. It does not have decongestant properties, meaning it does not help to relieve nasal congestion or stuffiness. Pseudoephedrine, oxymetazoline, and tetrahydrazoline are all decongestant drugs commonly used to alleviate nasal congestion.Rate this question:
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Current Version
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Mar 20, 2023Quiz Edited by
ProProfs Editorial Team -
Mar 01, 2009Quiz Created by
Marykatekish
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