Biolological Explanations Of Schizophrenia
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Explore the biological underpinnings of schizophrenia in this focused quiz. Assess your understanding of key concepts like dopamine's role, effects of phenothiazines, and innovative research findings using PET scans, enhancing both academic knowledge and practical insights into this complex disorder.
Questions and Answers
- 1.
Which neurotransmitter is thought to play a role in schizophrenia
- A.
Serotonin
- B.
Dopamine
- C.
Phenothiazine
Correct Answer
B. DopamineExplanation
Dopamine is the correct answer because it is widely believed that an imbalance of dopamine in the brain is associated with the development of schizophrenia. Excess dopamine activity in certain areas of the brain can lead to symptoms such as hallucinations and delusions, which are characteristic of schizophrenia. Medications that target dopamine receptors are often used to help manage these symptoms. Serotonin and phenothiazine are not directly implicated in schizophrenia, although they may have some secondary effects on the disorder.Rate this question:
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- 2.
These drugs inhibit dopamine activity
- A.
LSD hallucinogens
- B.
Amphetamines
- C.
Phenothiazines
Correct Answer
C. PhenothiazinesExplanation
Phenothiazines are a class of drugs that are known to inhibit dopamine activity. Dopamine is a neurotransmitter that plays a role in various brain functions, including mood regulation and reward-motivated behavior. By inhibiting dopamine activity, phenothiazines can help alleviate symptoms of certain mental disorders, such as schizophrenia and bipolar disorder. LSD hallucinogens and amphetamines, on the other hand, do not directly inhibit dopamine activity but rather have different mechanisms of action.Rate this question:
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- 3.
These researchers discovered that amphetamines induce schizophrenia symptoms in rats:
- A.
Weinberger et al (1987)
- B.
Brown et al (1986)
- C.
Randrup and Munkvad (1966)
Correct Answer
C. Randrup and Munkvad (1966)Explanation
Randrup and Munkvad (1966) discovered that amphetamines induce schizophrenia symptoms in rats. This suggests a potential link between amphetamine use and the development of schizophrenia-like symptoms in animals. The study conducted by Randrup and Munkvad provides evidence for the hypothesis that amphetamines can contribute to the development or exacerbation of schizophrenia symptoms.Rate this question:
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- 4.
What did Falkai et al (1988) discover when examining the brains of patients with schizophrenia after death?
- A.
An increase in dopamine in the left amygdala
- B.
A reduction in dopamine in the left amygdala
- C.
Larger ventricles containing cerebrospinal fluid?
Correct Answer
A. An increase in dopamine in the left amygdalaExplanation
Falkai et al (1988) discovered an increase in dopamine in the left amygdala when examining the brains of patients with schizophrenia after death. This finding suggests that there may be an abnormality in dopamine regulation in the left amygdala among individuals with schizophrenia. Dopamine is a neurotransmitter that plays a role in various brain functions, including motivation, reward, and emotional processing. The increased dopamine levels in the left amygdala could potentially contribute to the symptoms and pathophysiology of schizophrenia.Rate this question:
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- 5.
Who discovered increased dopamine receptor activity in the caudate nucleus putamen?
- A.
Flaum et al (1995)
- B.
Buchsbaum et al (1990)
- C.
Owen et al (1978)
Correct Answer
C. Owen et al (1978)Explanation
Owen et al (1978) discovered increased dopamine receptor activity in the caudate nucleus putamen.Rate this question:
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- 6.
Wong et al were able to study live brains using which technology?
- A.
MRI
- B.
PET scans
- C.
X rays
Correct Answer
B. PET scansExplanation
Wong et al were able to study live brains using PET scans. PET scans, or positron emission tomography scans, are a type of imaging technology that use a radioactive substance injected into the body to produce detailed images of the brain's activity. This allows researchers to study brain function and activity in real-time, providing valuable insights into various neurological processes and disorders. MRI and X-rays, on the other hand, are not typically used for studying live brains as they do not provide the same level of functional information as PET scans.Rate this question:
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- 7.
One of the most effective drugs in the treatment of schizophrenia is clozapine. This suggests dopamine cannot be the sole factor because
- A.
It increases dopamine levels
- B.
It acts on the serotonin system
- C.
It reduces the size of brain ventricles
Correct Answer
B. It acts on the serotonin systemExplanation
The correct answer is that clozapine acts on the serotonin system. This suggests that dopamine cannot be the sole factor in the treatment of schizophrenia because clozapine's effectiveness is not solely due to its impact on dopamine levels. The fact that it acts on the serotonin system indicates that there are other neurotransmitters involved in the pathology of schizophrenia, and targeting multiple systems is necessary for effective treatment. Additionally, the reduction in the size of brain ventricles is not directly related to the action of clozapine on the serotonin system.Rate this question:
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- 8.
Dopamine is unlikely to be the sole factor in schizophrenia as it is implicated in other mental disorders such as
- A.
Depression
- B.
Obsessive Compulsive Disorder
- C.
Mania
Correct Answer
C. ManiaExplanation
Dopamine is unlikely to be the sole factor in schizophrenia because it is also involved in other mental disorders such as depression, obsessive-compulsive disorder, and mania. This suggests that there are multiple factors at play in the development of schizophrenia, and dopamine alone cannot explain the complexity of the disorder.Rate this question:
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- 9.
A criticism of the dopamine hypothesis is that it is
- A.
Expansionist
- B.
Reductive
- C.
Reductionist
Correct Answer
C. ReductionistExplanation
The criticism of the dopamine hypothesis is that it is reductionist. This means that it oversimplifies the complex nature of mental health disorders by attributing them solely to imbalances in dopamine levels. Critics argue that mental health disorders are multifaceted and involve various factors, such as genetics, environment, and other neurotransmitters. Therefore, reducing the explanation to solely dopamine disregards these other important aspects and fails to provide a comprehensive understanding of mental health disorders.Rate this question:
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- 10.
Other factors which are ignored by biochemical explanations are:
- A.
Stress and irrational thoughts
- B.
Genetic factors
- C.
Neurotransmitters
Correct Answer
A. Stress and irrational thoughtsExplanation
Biochemical explanations of behavior often focus on the role of neurotransmitters and genetic factors in influencing human behavior. However, these explanations often overlook the significant impact of stress and irrational thoughts on behavior. Stress can lead to physiological changes in the body, affecting neurotransmitter levels and ultimately influencing behavior. Similarly, irrational thoughts can distort perception and lead to maladaptive behaviors. Therefore, it is important to consider these factors alongside biochemical explanations to gain a more comprehensive understanding of human behavior.Rate this question:
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- 11.
Neuroanatomical Explanations can be studied using Magnetic Resonance ________
Correct Answer
Electrons
Imaging
Positrons - 12.
________ et al found decreased brain weight.
Correct Answer
Brown
Falkai
DesmondExplanation
The given correct answer for this question is "Brown, Falkai, Desmond". This suggests that a study conducted by Brown, Falkai, and Desmond found a decrease in brain weight. However, without additional context or information about the study, it is difficult to provide a more detailed explanation.Rate this question:
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Current Version
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Apr 17, 2024Quiz Edited by
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Feb 21, 2010Quiz Created by
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