1.
Muscle stretch leads to a direct increase in firing rate of which type of nerve?
Correct Answer
C. Group Ia fibers
Explanation
Group Ia afferent fibers innervate intrafusal fibers of the muscle spindle. When the intrafusal fibers are stretched, the group Ia fibers fire and activate the stretch reflex, which causes the muscle to return to its resting length.
2.
Which of the following is a characteristic of nuclear bag fibers?
Correct Answer
B. They detect dynamic changes in muscle length
Explanation
Explanation: Nuclear bag fibers are a type of intrafusal muscle fiber found within muscle spindles. They are specialized to detect dynamic changes in muscle length and the rate of change in length. These fibers are essential for proprioception, providing the central nervous system with information about muscle stretch and movement. They are not extrafusal muscle fibers, do not give rise to group Ib afferents, and are not innervated by alpha-motoneurons; instead, they are typically associated with gamma-motoneurons.
3.
Which reflex is responsible for polysynaptic excitation of contralateral extensors?
Correct Answer
C. Flexor withdrawal reflex
Explanation
Flexor withdrawal is a polysynaptic reflex that is used when a person touches a hot stove or steps on a tack. On the ipsilateral side of the painful stimulus, there is flexion (withdrawal); on the contralateral side, there is extension to maintain balance.
4.
Cutting which structure causes blindness in the temporal fields of the left and right eyes?
Correct Answer
B. Optic chiasm
Explanation
Optic nerve fibers from both temporal receptor fields cross at the optic chiasm.
5.
Which of the following structures has a primary function to coordinate rate, range, force, and direction of movement?
Correct Answer
E. Cerebellum
Explanation
Output of Purkinje cells from the cerebellar cortex to deep cerebellar nuclei is inhibitory. This output modulates movement and is responsible for the coordination that allows one to "catch a fly."
6.
Sensory receptor potentials
Correct Answer
D. Are graded in size, depending on stimulus intensity
Explanation
Receptor potentials are graded potentials that may bring the membrane potential of the receptor cell either toward (depolarizing) or away from (hyperpolarizing) threshold. Receptor potentials are not action potentials, although action potentials (which are all-or-none) may result if the membrane potential reaches threshold
7.
Complete transection of the spinal cord at the level of T1 would most likely result in
Correct Answer
A. Temporary loss of stretch reflexes belowthe lesion
Explanation
Transection of the spinal cord causes "spinal shock" and loss of all reflexes below the level of the lesion. These reflexes, which are local circuits within the spinal cord, will return with time or become hypersensitive. Proprioception is permanently (rather than temporarily) lost because of the interruption of sensory nerve fibers. Fibers above the lesion are intact.
8.
The inability to perform rapidly alternating movements (dysdiadochokinesia) is associated with lesions of the
Correct Answer
C. Cerebellum
Explanation
Coordination of movement (synergy) is the function of the cerebellum. Lesions of the cerebellum cause ataxia, lack of coordination, poor execution of movement, delay in initiation of movement, and inability to perform rapidly alternating movements. The premotor and motor cortices plan and execute movements. Lesions of the substantia nigra, a component of the basal ganglia, result in tremors, lead-pipe rigidity, and poor muscle tone (Parkinson's disease).
9.
Which autonomic receptor is activated by low concentrations of epinephrine released from the adrenal medulla and causes vasodilation?
Correct Answer
C. Adrenergic p, receptors
Explanation
B2 Receptors on vascular smooth muscle produce vasodilation. a Receptors on vascular smooth muscle produce vasoconstriction. Because 02 receptors are more sensitive to epinephrine than are a receptors, low doses of epinephrine produce vasodilation, and high doses produce vasoconstriction.
10.
A lesion of the chorda tympani nerve would most likely result in
Correct Answer
D. Impaired taste function
Explanation
The chorda tympani [cranial nerve (CN) VII] is involved in taste; it innervates the anterior two-thirds of the tongue.
11.
Which of the following would produce maximum excitation of the hair cells in the right horizontal semicircular canal?
Correct Answer
D. Rotating the head to the right
Explanation
The semicircular canals are involved in angular acceleration or rotation. Hair cells of the right semicircular canal are excited (depolarized) when there is rotation to the right. This rotation causes bending of the tereocilia toward the kinocilia, and this bending produces depolarization of the hair cell. Ascent in an elevator would activate the saccules, which detect linear acceleration.
12.
Pathogens that produce fever cause
Correct Answer
C. Shivering
Explanation
Pathogens release interleukin-1 (IL-1) from phagocytic cells. IL- 1 then acts to increase the production of prostaglandins, ultimately raising the temperature set point in the anterior hypothalamus. The hypothalamus now "thinks" that the body temperature is too low (because the core temperature is lower than the new set-point temperature) and initiates mechanisms for generating heat—shivering, vasoconstriction, and shunting of blood away from the venous plexus near the skin surface.
13.
Which of the following statements about the olfactory system is true?
Correct Answer
A. The receptor cells are neurons
Explanation
Cranial nerve (CN) I innervates the olfactory epithelium. Its axons are C fibers. Fracture of the cribriform plate can tear the delicate olfactory nerves and thereby eliminate the sense of smell (anosmia); however, the ability to detect ammonia is left intact. Olfactory receptor cells are unique in that they are true neurons that are continuously replaced
from undifferentiated stem cells.
14.
Which of the following is a step in photoreception in the rods?
Correct Answer
B. Metarhodopsin II activates transducin
Explanation
Photoreception involves the following steps. Light converts 11-cis retinal to all-trans retinal, which is converted to such intermediates as metarhodopsin II. Metarhodopsin II activates a stimulatory G protein (transducin), which activates a phosphodiesterase. Phosphodiesterase breaks down cyclic guanosine monophosphate (cGMP), so intracellular
cGMP levels decrease, causing closure of Na + channels in the photoreceptor cell membrane and hyperpolarization. Hyperpolarization of the photoreceptor cell membrane inhibits the release of neurotransmitter. If the neurotransmitter is excitatory, then the bipolar cell will be hyperpolarized (inhibited). If the neurotransmitter is inhibitory, then the bipolar cell will be depolarized (excited).
15.
Which of the following autonomic drugs acts by stimulating adenylate cyclase?
Correct Answer
D. NorepinepHrine
Explanation
Among the autonomic drugs, only B1 and B2 adrenergic agonists act by stimulating adenylate cyclase. Norepinephrine is a B1 agonist. Atropine is a muscarinic cholinergic antagonist. Clonidine is an a2 adrenergic agonist. Curare is a nicotinic cholinergic antagonist. Phentolamine is an al adrenergic antagonist. Phenylephrine is an al adrenergic agonist. Propranolol is a B1 and B2 adrenergic antagonist.
16.
Aballet dancer spins to the left. During the spin, her eyes snap quickly to the left. This fast eye movement is
Correct Answer
A. Nystagmus
Explanation
The fast eye movement that occurs during a spin is nystagmus. It occurs in the same direction as the rotation. After the spin, post-rotatory nystagmus occurs in the opposite direction.
17.
Which of the following has a much lower concentration in the cerebrospinal fluid (CSF) than in cerebral capillary blood?
Correct Answer
D. Protein
Explanation
Cerebrospinal fluid (CSF) is similar in composition to the interstitial fluid of the brain. Therefore, it is similar to an ultrafiltrate of plasma and has a very low protein concentration because large protein molecules cannot cross the blood–brain barrier. There are other differences in composition between CSF and blood that are created by transporters in the choroid plexus, but the low protein concentration of CSF is the most dramatic difference.