1.
Azilsartan contains which moiety (Ring)?
Correct Answer
C. Oxo- Oxadiazole
Explanation
The correct answer is Oxo-Oxadiazole. Oxo-Oxadiazole is a five-membered ring that contains both an oxygen (oxo) and a nitrogen (oxadiazole) atom. Azilsartan is a medication that belongs to the class of angiotensin II receptor antagonists, and its chemical structure includes an Oxo-Oxadiazole ring.
2.
Azilsartan offers additional Vasodilation due to?
Correct Answer
A. Action on ACE-2/ Ang (1-7) and mass receptor
Explanation
Azilsartan offers additional vasodilation due to its action on ACE-2/ Ang (1-7) and mass receptor. ACE-2 is an enzyme that converts angiotensin II (Ang II) to angiotensin 1-7 (Ang 1-7), which has vasodilatory effects. By acting on ACE-2 and the mass receptor, Azilsartan promotes the production of Ang 1-7, leading to vasodilation and lowering of blood pressure. This mechanism of action differentiates Azilsartan from other angiotensin receptor blockers (ARBs) and contributes to its additional vasodilatory effects.
3.
Azilsartan has got ____IC50 value than Olmesartan?
Correct Answer
B. Lower
Explanation
The question is asking which drug, Azilsartan or Olmesartan, has a lower IC50 value. The IC50 value is a measure of the concentration of a drug needed to inhibit 50% of a specific biological or biochemical function. Therefore, if Azilsartan has a lower IC50 value than Olmesartan, it means that Azilsartan is more effective at inhibiting the specific function being measured.
4.
Which is one of the most effective 2 drug combination to treat Hypertension according to Hurst's The Heart textbook?
Correct Answer
C. ARB & Diuretics
Explanation
According to Hurst's The Heart textbook, one of the most effective 2 drug combinations to treat Hypertension is ARB (Angiotensin Receptor Blockers) and Diuretics.
5.
ALLHAT Study compared the Cardioprotective effects of Chlorthalidone with
Correct Answer
C. Lisinopril & Amlodipine
Explanation
The ALLHAT study compared the cardioprotective effects of Chlorthalidone with different medications. The correct answer is Lisinopril & Amlodipine, as this combination was one of the medications compared in the study.
6.
Azilsartan is ____% more effective than Olmesartan for BP control
Correct Answer
A. 31%
Explanation
Azilsartan is 31% more effective than Olmesartan for BP control. This means that Azilsartan has a greater impact on reducing blood pressure compared to Olmesartan, with a difference of 31%. This suggests that Azilsartan may be a more suitable option for individuals looking to effectively control their blood pressure.
7.
Is dose adjustment of Azilsartan is required in Renal impairment patients?
Correct Answer
B. No
Explanation
No, dose adjustment of Azilsartan is not required in renal impairment patients. This is because Azilsartan is primarily eliminated through the bile and feces, rather than through the kidneys. Therefore, renal impairment does not significantly affect the pharmacokinetics of Azilsartan, and the standard dose can be used in these patients.
8.
Chlorthalidone belongs to which class of diuretics??
Correct Answer
D. Thiazide like diuretics
Explanation
Chlorthalidone belongs to the class of thiazide-like diuretics. Thiazide-like diuretics are similar in structure and function to thiazide diuretics, but they have a longer duration of action. These diuretics work by increasing the excretion of sodium and water from the body, which helps to reduce fluid retention and lower blood pressure. Chlorthalidone is commonly used in the treatment of hypertension and edema.
9.
What is the mode of action of Chlorthalidone?
Correct Answer
C. Reduction in both blood volume and peripHeral resistance
Explanation
Chlorthalidone works by reducing both blood volume and peripheral resistance. This means that it helps to decrease the amount of fluid in the blood vessels, as well as relax and widen the blood vessels themselves. By doing so, Chlorthalidone helps to lower blood pressure and improve blood flow throughout the body.
10.
What is the half life of Chlorthalidone?
Correct Answer
D. 45-60 Hrs
Explanation
The half-life of Chlorthalidone is the amount of time it takes for half of the drug to be eliminated from the body. In this case, the correct answer is 45-60 hours, which means that it takes approximately 45-60 hours for half of the Chlorthalidone to be eliminated from the body. This information is important for determining the dosing frequency and duration of action of the drug.
11.
Which Clinical trial concludes one day extra life expectancy after one month active treatment with Chlorthalidone?
Correct Answer
D. SHEP
Explanation
The correct answer is SHEP. The SHEP (Systolic Hypertension in the Elderly Program) clinical trial concluded that one month of active treatment with Chlorthalidone resulted in one day extra life expectancy.
12.
Chlorthalidone _________ potassium level & Azilsartan ___________potassium level
Correct Answer
C. Chlorthalidone decreases potassium level & Azilsartan increases potassium level
Explanation
Chlorthalidone is a diuretic medication that helps the body get rid of excess water and salt. One of its side effects is that it can decrease the levels of potassium in the body. On the other hand, Azilsartan is an angiotensin receptor blocker (ARB) medication that helps relax blood vessels and lower blood pressure. It does not have a significant effect on potassium levels. Therefore, the correct answer is that Chlorthalidone decreases potassium level, while Azilsartan does not have a significant effect on potassium level.
13.
Which one of the following is correct match ( Brand Name & Company)?
Correct Answer
B. Zilarbi CT- Emcure
Explanation
The correct match for the brand name and company is Zilarbi CT- Emcure.
14.
What are the Total 4 Symptoms (T4S) in childern?
Correct Answer
B. Sneezing, Rhinorrhea, Nasal & Eye Itching
Explanation
The correct answer is Sneezing, Rhinorrhea, Nasal & Eye Itching. This is because the question asks for the total 4 symptoms (T4S) in children, and this option includes four symptoms: sneezing, rhinorrhea (runny nose), and itching in both the nasal and eye areas.
15.
Diuretics ________the effectiveness of ARBs.
Correct Answer
D. Increase
Explanation
Diuretics increase the effectiveness of ARBs.
16.
What is the MRP of ZILARTA -CT40?
Correct Answer
A. 109
Explanation
The MRP of ZILARTA-CT40 is 109.
17.
What is the MRP of ZILARBI 40?
Correct Answer
D. 90
Explanation
The MRP (Maximum Retail Price) of ZILARBI 40 is 90.
18.
Which Specialty should be the Major Focus for Zilarta?
Correct Answer
A. Cardiologist
Explanation
Zilarta should majorly focus on becoming a cardiologist because this specialty deals with the diagnosis, treatment, and prevention of heart diseases. As cardiovascular diseases are one of the leading causes of death worldwide, specializing in cardiology will enable Zilarta to provide specialized care to patients with heart conditions, such as heart attacks, heart failure, and arrhythmias. By becoming a cardiologist, Zilarta can contribute to improving the overall cardiovascular health of individuals and potentially save lives through early detection and effective treatment of heart diseases.
19.
Why 80 Mg needs to be given Special Focus?
Correct Answer
D. All of the Above
Explanation
The correct answer is "All of the Above." This means that all of the given reasons are valid explanations for why 80 mg needs to be given special focus. The market for higher strength is expected to grow at a faster rate, so focusing on 80 mg can help increase sales volume. Additionally, Zilarta 80 mg is the most economical brand compared to competitors, which further justifies the need for special focus on this strength.
20.
What is the MRP of ZILSAR 80?
Correct Answer
B. 165
Explanation
The correct answer is 165.
21.
Hypokalemia means
Correct Answer
D. None of the above
Explanation
Hypokalemia refers to a condition of decreased potassium levels in the blood. It is not related to increased levels of potassium, calcium, or sodium.
22.
Head to Head study of Chlorthalidone vs Hydrochlorothiazide is
Correct Answer
B. MRFIT
23.
Which study spoke about aggressive BP control saves Lives?
Correct Answer
A. SPRINT
Explanation
The study that spoke about aggressive BP control saving lives is SPRINT.
24.
What is the Goal BP for adults?
Correct Answer
D. 140/90
Explanation
The goal blood pressure (BP) for adults is 140/90. This means that the ideal blood pressure reading for adults is a systolic pressure of 140 mmHg and a diastolic pressure of 90 mmHg. Maintaining a blood pressure within this range is important for overall cardiovascular health and reducing the risk of heart disease and stroke.
25.
____________% of patients achieved BP control with Azilsartan and Chlorthalidone Fixed Dose combination
Correct Answer
A. 81%
Explanation
81% of patients achieved blood pressure control with the combination of Azilsartan and Chlorthalidone. This suggests that the fixed dose combination of these two medications is effective in controlling blood pressure in a significant majority of patients.
26.
To be a successful TE which of these are right
Correct Answer
D. All of the above
Explanation
The correct answer is "All of the above" because to be a successful TE (Technical Engineer), it is important to have a combination of doctor selection and in-clinic performance with a call average of 12 per day. Additionally, developing relationships with clients and following up on their needs, as well as implementing solutions effectively, are crucial for success in this role. Therefore, all of these factors are necessary for a TE to be successful.
27.
RCPA comprises of which of the following actions
Correct Answer
D. All of the above
Explanation
The correct answer is "All of the above." RCPA (Retail Chemist Prescription Audit) comprises of all the mentioned actions, including Doctor and Product Survey- Quantification, Product Survey, and Competitor's data and use of personal relationship to influence. These actions are essential in conducting a comprehensive RCPA to gather information about doctors, products, competitors, and the use of personal relationships to influence prescriptions.
28.
Good detailng includes
Correct Answer
D. All of the above
Explanation
Good detailing includes all of the mentioned factors: verbatim of detailing, voice modulation, body language, and VAF handling & proper usage of pointer. Verbatim of detailing refers to accurately conveying information without omitting any important details. Voice modulation and body language play a crucial role in effectively communicating and engaging with the audience. VAF handling and proper usage of pointer ensure smooth navigation and interaction during the detailing process. Therefore, all of these factors contribute to good detailing.
29.
Input should be Given to which Dr?
Correct Answer
B. As per organisation strategy
Explanation
This answer suggests that the input should be given to the Dr according to the organization's strategy. This implies that there may be a specific plan or guideline in place that determines which Dr should receive the input. The organization's strategy likely takes into consideration factors such as expertise, workload, and availability when determining which Dr should handle the input.
30.
Why does a TE needs to do a call closing?
Correct Answer
A. To demand prescription
Explanation
A TE needs to do a call closing to demand prescription from the doctor. This is important because prescription is required for the sale and distribution of certain medications. By requesting the prescription, the TE ensures that the doctor follows the proper procedure and provides the necessary documentation for the medication to be prescribed and dispensed. This helps to maintain legal and ethical standards in the pharmaceutical industry.
31.
Importance of post call analysis
Correct Answer
A. Helps us to check Dr intrest, validate our Rcpa findings and helps us to check effectivness of the input and our communication
Explanation
Post call analysis is important because it allows us to assess the level of interest shown by the doctors, validate our Rcpa findings, and evaluate the effectiveness of our communication and input. This analysis helps us understand if the doctors are receptive to our product and if our efforts are yielding the desired results. It is not solely the responsibility of the Area Medical Specialist (AMS), as fieldwork is also crucial in gathering information and engaging with doctors.
32.
How can a TE earn Incentives
Correct Answer
C. Meeting the Dr , Tgt Acheivment & Minimum Growth as per the oragnisation norms
Explanation
A TE (Territory Executive) can earn incentives by meeting the doctor, achieving the target, and demonstrating minimum growth as per the organization's norms. This means that in order to earn incentives, the TE must not only have successful meetings with doctors but also achieve their sales targets and show a minimum level of growth as set by the organization. Simply meeting the doctor or achieving the target alone is not sufficient to earn incentives.
33.
Maxminum amount of money can be earned / month in Work Norm Incentive
Correct Answer
C. 1500
Explanation
The maximum amount of money that can be earned per month in the Work Norm Incentive is 1500. This means that no matter how much effort or work is put in, the maximum payout will be 1500. It is possible that there are certain criteria or limitations set in place that prevent earning more than this amount.
34.
What is the full form of RCPA?
Correct Answer
B. Retail Chemist Prescription Audit
Explanation
The correct answer is "Retail Chemist Prescription Audit." RCPA stands for Retail Chemist Prescription Audit, which refers to the process of auditing and analyzing prescription data in retail pharmacies. This helps in monitoring and evaluating the prescribing patterns, medication usage, and overall quality of pharmaceutical care provided by the retail chemists.
35.
RCPA should done
Correct Answer
D. Before Dr Call
Explanation
The correct answer is "Before Dr Call." This means that the RCPA (which stands for Routine Clinical Pathology Analysis) should be done before making a call to the doctor. It is important to complete the analysis and have the results ready before discussing the patient's condition with the doctor. This ensures that the doctor has all the necessary information to make informed decisions and provide appropriate medical advice.
36.
RCPA should start with
Correct Answer
D. Introduction & Rapport building
Explanation
The correct answer is Introduction & Rapport building. This is because when starting an RCPA (Rapport, Contact, Problem, Action) process, it is important to begin by establishing a connection with the person you are interacting with. This involves introducing yourself and building rapport, which helps to create a positive and comfortable environment for further communication. By starting with Introduction & Rapport building, you can establish trust and establish a foundation for effective problem-solving and action-taking.
37.
In rapport building we should do
Correct Answer
D. Both A & B
Explanation
In rapport building, it is important to introduce ourselves to establish a connection with the other person. This helps in creating a friendly and comfortable environment. Additionally, asking the name of the retailer shows interest and respect towards them, which further helps in building rapport. Therefore, both options A and B are correct as they contribute to effective rapport building.
38.
During RCPA need to ask about
Correct Answer
D. All of above
Explanation
During a RCPA (Retail Chemist Prescription Audit), it is important to gather quantified information about our brand, as well as the competitor brand. This includes data such as sales figures, market share, and customer feedback. Additionally, it is crucial to inquire about the pack and price of the competitor brand to understand their pricing strategy and how it compares to our own. By asking about all of the above factors, we can gain a comprehensive understanding of the market and make informed decisions to improve our brand's performance.
39.
RCPA is helpful to
Correct Answer
D. All of above
Explanation
RCPA (Retail Customer Purchase Analysis) is a tool that is helpful in various ways. Firstly, it can assist in selecting the right customer for the right brand by analyzing their purchase patterns and preferences. Secondly, it can provide insights into the prescription habits of doctors, which can be valuable information when targeting specific medical professionals. Lastly, RCPA can be used to plan a strategy by identifying trends, understanding customer behavior, and making informed decisions based on the data collected. Therefore, the correct answer is "All of the above."
40.
During Retail call we need to give information to retailer about
Correct Answer
C. Bonus
Explanation
During a retail call, it is important to provide information to the retailer about various aspects of the brand. This includes the mechanism of action of the brand, which explains how the product works and its effects. The USP's (Unique Selling Points) of the brand should also be discussed, highlighting the unique features or benefits that set it apart from competitors. Additionally, information about any bonuses or incentives associated with the brand should be communicated to the retailer. Lastly, indications, which refer to the specific conditions or situations in which the brand is recommended or effective, should also be discussed.
41.
If a brand is lying at chemist and not moving then we should
Correct Answer
B. Liquidate it
Explanation
If a brand is lying at a chemist and not moving, the best course of action would be to liquidate it. Liquidating a brand refers to selling off its assets, usually at a discounted price, in order to recover as much value as possible. This is typically done when a brand is no longer profitable or relevant in the market. Ignoring it would not address the issue, asking the chemist to return it may not be feasible or practical, and none of the above options provide a solution to the problem of a stagnant brand.
42.
RCPA will help to do
Correct Answer
B. Precall Planning
Explanation
The given answer, "Precall Planning," is the correct one because RCPA stands for "Recall, Comprehend, Plan, and Act." It is a framework used in sales to analyze and improve the effectiveness of sales calls. Precall planning is an important step in the RCPA process as it involves preparing for a sales call by researching the prospect, setting objectives, and strategizing the approach. This helps the salesperson to be better prepared and increase the chances of a successful sales call. The repetition of "Precall Planning" in the options suggests that it is the most important and relevant step in the given context.
43.
To know the Potential of a Dr by RCPA we need to
Correct Answer
C. Both A & B
Explanation
To know the potential of a doctor by RCPA, it is necessary to analyze the Rx wise and Value wise sales of our brand and competitor brand. By comparing the sales of our brand and competitor brand, we can understand the market share and performance of each brand. This analysis helps in identifying the potential of a doctor in terms of prescribing our brand or competitor brand. Hence, both options A and B are required to accurately determine the potential of a doctor by RCPA.
44.
If retailer is Busy with patient then
Correct Answer
C. We should wait untill he is free
Explanation
The correct answer is to wait until the retailer is free. This implies that the retailer is occupied with a patient and therefore unable to assist at the moment. It is best to be patient and wait for the retailer to become available before seeking their assistance or information.
45.
We should meet the Retailer
Correct Answer
C. On his convenient time
Explanation
The correct answer is "On his convenient time". This means that the meeting with the retailer should be scheduled based on his availability and preference. It is important to consider the retailer's convenience in order to ensure a successful and productive meeting.
46.
During Retailer call Pob can ensure
Correct Answer
C. Both A & B
Explanation
During a retailer call, Pob can ensure the availability of YourBrand and also ensure that prescriptions do not get bounced. This means that Pob can make sure that the retailer has enough stock of YourBrand products and can also provide assistance in ensuring that prescriptions are properly processed without any issues.
47.
After taking the POB we should ensure the
Correct Answer
D. All of the above
Explanation
After taking the POB (Purchase Order Book), it is important to ensure that the order copy is handed over to the stockist, the supply of goods is made, and a follow-up is done to confirm if the stocks have been received by the chemist. All of these steps are necessary to complete the process and ensure that the order is successfully fulfilled.