1.
Surface activity and low toxic potential?
Correct Answer
A. Benzocaine
Explanation
Benzocaine is the correct answer because it exhibits surface activity and has a low toxic potential. Surface activity refers to the ability of a substance to interact with the surface of a material or tissue. Benzocaine is commonly used as a topical anesthetic, meaning it is applied directly to the surface of the skin or mucous membranes to numb the area. It is known for its low toxicity, meaning it is relatively safe to use and has a low risk of causing harmful side effects.
2.
Which of the following drugs can cause methemoglonemia?
Correct Answer
A. Prilocaine
Explanation
Prilocaine is a local anesthetic that can cause methemoglobinemia. Methemoglobinemia is a condition where the iron in hemoglobin is oxidized to the ferric state, resulting in reduced oxygen-carrying capacity of the blood. Prilocaine is metabolized in the body to o-toluidine, which causes the oxidation of hemoglobin. This can lead to symptoms such as cyanosis, shortness of breath, and fatigue. Treatment involves administration of methylene blue, which helps to convert methemoglobin back to its normal state.
3.
Vasoconstrictor in Local anesthetic solution is?
Correct Answer
A. Reduce toxic effects of LA solution
Explanation
The vasoconstrictor in a local anesthetic solution helps to reduce the toxic effects of the solution. Vasoconstriction narrows the blood vessels at the site of injection, which in turn reduces the absorption of the anesthetic into the bloodstream. This helps to minimize the systemic toxicity of the local anesthetic, making it safer for use.
4.
When injecting Local solutionin maxilla on buccal side. The technique is ?
Correct Answer
A. Supra periosteal
Explanation
The correct technique for injecting a local solution in the maxilla on the buccal side is the supra periosteal technique. This involves injecting the solution just above the periosteum, which is the membrane that covers the outer surface of the bone. This technique allows for effective anesthesia in the area and helps to minimize discomfort for the patient.
5.
Disto buccal root of upper first molar is supplied by:?
Correct Answer
A. Posterior superior alveolar nerve
Explanation
The disto buccal root of the upper first molar is supplied by the posterior superior alveolar nerve. This nerve is a branch of the maxillary nerve and provides sensory innervation to the maxillary molars, including the disto buccal root of the upper first molar. The middle superior alveolar nerve supplies the mesiobuccal root of the upper first molar, while the infraorbital nerve supplies the anterior teeth and the buccal nerve supplies the buccal mucosa. The mental nerve supplies the lower anterior teeth.
6.
Technique of anesthesia in which local anesthetic solution is injected into the vein is ?
Correct Answer
A. Intra venous regional anesthesia
Explanation
Intra venous regional anesthesia is the technique of anesthesia in which a local anesthetic solution is injected into the vein. This allows for the anesthetic to be distributed throughout the body via the bloodstream, providing a regional anesthesia effect. This technique is commonly used for procedures that require a larger area of the body to be numbed or for longer durations of anesthesia.
7.
You suspect that your patient has an enlarged submandibular salivary gland. You expect the enlarged gland?
Correct Answer
A. To be palpable both intra- and extraorally
Explanation
An enlarged submandibular salivary gland is expected to be palpable both intra- and extraorally. This means that the enlargement can be felt both inside the mouth and outside, on the surface of the neck. Palpation is a physical examination technique where the healthcare provider uses their hands to feel for abnormalities or changes in the body. In this case, the enlarged gland can be felt by touch, indicating its presence and size. This information can help in diagnosing and treating the patient's condition.
8.
During an inferior alveolar nerve block the needle ideally passes?
Correct Answer
A. Anterior and lateral to medial pterygoid
Explanation
During an inferior alveolar nerve block, the needle ideally passes anterior and lateral to the medial pterygoid muscle. This positioning allows for accurate administration of the anesthetic solution to the inferior alveolar nerve, which is located in close proximity to the medial pterygoid muscle. By passing the needle anterior and lateral to the muscle, the risk of damaging the nerve or other surrounding structures is minimized, ensuring a successful and safe nerve block procedure.
9.
You notice that your patient's submandibular lymph nodes are enlarged. You would look for potential infection sites in the?
Correct Answer
A. Hard palate, upper lip, upper central incisor and lower first molar
Explanation
The correct answer is hard palate, upper lip, upper central incisor and lower first molar. Enlarged submandibular lymph nodes can indicate an infection in the head and neck region. The lymph nodes drain lymphatic fluid from these areas, so an infection in the hard palate, upper lip, upper central incisor, or lower first molar could cause the lymph nodes to become enlarged. By examining these potential infection sites, the healthcare professional can determine the source of the infection and provide appropriate treatment.
10.
You notice a lesion on the labial alveolar mucosa of the lower right lateral incisor tooth of one of your patients and decide to take a biopsy to send for oral pathology report Which nerve would require local anesthesia in order to carry out a pain-free biopsy?
Correct Answer
A. The incisive nerve
Explanation
The incisive nerve would require local anesthesia in order to carry out a pain-free biopsy. The incisive nerve is responsible for providing sensory innervation to the labial alveolar mucosa of the lower anterior teeth, including the lateral incisor tooth. By administering local anesthesia to the incisive nerve, the patient will not feel any pain during the biopsy procedure.
11.
The regional lymphatic drainage of the left side of the tip of the tongue is to the?
Correct Answer
A. Left and right submental lympH nodes
Explanation
The regional lymphatic drainage of the left side of the tip of the tongue is to the left and right submental lymph nodes. These lymph nodes are located beneath the chin, near the midline. They receive lymphatic drainage from the tongue, floor of the mouth, and lower lip. The submental lymph nodes are part of the submandibular lymph node group, which also includes the submandibular lymph nodes. However, in this case, the drainage is specifically to the submental lymph nodes on both the left and right sides.
12.
A successful inferior alveolar nerve block will produce anesthesia of the?
Correct Answer
A. Lower lip, mandibular teeth and labial gingivae of the anterior mandibular teeth
Explanation
A successful inferior alveolar nerve block will produce anesthesia of the lower lip, mandibular teeth, and labial gingivae of the anterior mandibular teeth. This is because the inferior alveolar nerve supplies sensory innervation to these areas.
13.
The mucosa of the hard palate is?
Correct Answer
A. Keratinised and has submucosa and minor salivary glands posterolaterally
Explanation
The correct answer is "keratinised and has submucosa and minor salivary glands posterolaterally." The hard palate is the bony structure that forms the roof of the mouth. The mucosa of the hard palate is keratinized, which means it has a tough outer layer of keratin, similar to the skin. It also has a submucosa, which is a layer of connective tissue beneath the mucosa. Additionally, there are minor salivary glands located posterolaterally on the hard palate, which contribute to saliva production.
14.
A successful infraorbital nerve block will produce anaesthesia of the?
Correct Answer
A. Maxillary anterior teeth, their labial gingivae and the upper lip
Explanation
A successful infraorbital nerve block will produce anesthesia of the maxillary anterior teeth, their labial gingivae, and the upper lip. This is because the infraorbital nerve supplies sensory innervation to these areas.
15.
In a patient with a normal healthy mouth, you would expect the mucosa covering the alveolar process supporting the mandibular teeth to be?
Correct Answer
A. Ed below the mucogingival junction and light pink above it
Explanation
In a patient with a normal healthy mouth, the mucosa covering the alveolar process supporting the mandibular teeth would be expected to be light pink in color below the mucogingival junction and light pink above it. This is because the mucogingival junction is the area where the attached gingiva meets the alveolar mucosa, and the color of the mucosa can vary in different areas. The light pink color indicates a healthy and normal mucosal appearance.
16.
Advantage(s) of 5% lidocaine (Xylocaine
Correct Answer
A. No local irritation, even absorption and no systemic toxicity
Explanation
The advantage of using 5% lidocaine (Xylocaine) cream is that it does not cause any local irritation, it is absorbed evenly, and it does not pose any risk of systemic toxicity. This means that the cream can be applied to the skin without causing any discomfort or irritation at the application site. Additionally, the lidocaine is absorbed evenly into the skin, ensuring consistent and effective pain relief. Furthermore, there is no risk of the lidocaine entering the bloodstream and causing any toxic effects on the body.
17.
Local anesthetic used in greater than 50% of rhinolaryngologic cases:?
Correct Answer
A. Cocaine
Explanation
Cocaine is the correct answer because it is a local anesthetic that is commonly used in rhinolaryngologic cases. It has vasoconstrictive properties which help to reduce bleeding during procedures in the nose and throat. Additionally, cocaine has a rapid onset of action and provides effective anesthesia for a relatively short duration, making it suitable for these types of procedures. However, it is important to note that due to its potential for abuse and addictive properties, the use of cocaine as a local anesthetic is highly regulated and restricted.
18.
Mechanism(s) of local anesthetic action in epidural anesthesia:?
Correct Answer
A. Direct local anesthetic action on nerve roots and spinal cord following local anesthetic diffusion across the dura and diffusion of local anesthetic into paravertebral regions through the intervertebral foramina
Explanation
The correct answer is that the mechanism of local anesthetic action in epidural anesthesia involves both direct local anesthetic action on nerve roots and spinal cord following local anesthetic diffusion across the dura, as well as diffusion of the local anesthetic into paravertebral regions through the intervertebral foramina. This means that the local anesthetic directly affects the nerves and spinal cord, and also spreads to the surrounding areas through the intervertebral foramina, providing a wider area of anesthesia.
19.
Rationale for adding epinephrine to a local anesthetic solution:?
Correct Answer
A. Reduced local anesthetic systemic absorption and increased anesthetic concentration near nerve fibers
Explanation
The rationale for adding epinephrine to a local anesthetic solution is to achieve reduced local anesthetic systemic absorption and increased anesthetic concentration near nerve fibers. Epinephrine acts as a vasoconstrictor, causing constriction of blood vessels at the site of administration. This reduces the systemic absorption of the local anesthetic, preventing it from spreading throughout the body. At the same time, the vasoconstriction also helps in keeping the anesthetic solution concentrated near the nerve fibers, enhancing its effectiveness in blocking nerve conduction. Therefore, adding epinephrine to a local anesthetic solution provides both benefits of reduced systemic absorption and increased concentration near the target area.
20.
Zone of differential motor blockade may average up to four segments below the sensory level?
Correct Answer
A. Epidural
Explanation
The zone of differential motor blockade refers to the area where motor function is affected by anesthesia. In the case of epidural anesthesia, the motor blockade can extend up to four segments below the sensory level. This means that the muscles controlled by the affected nerves may experience decreased or loss of motor function. In contrast, spinal anesthesia typically only affects the sensory level without significant motor blockade. Therefore, the correct answer is epidural.
21.
Duration of sensory anesthesia is likely to be extended for abdominal regional anesthesia?
Correct Answer
A. False
Explanation
The given statement is "Duration of sensory anesthesia is likely to be extended for abdominal regional anesthesia." The correct answer is False. This means that the duration of sensory anesthesia is not likely to be extended for abdominal regional anesthesia. This suggests that the effect of the anesthesia on the sensory nerves in the abdominal region is not expected to last longer than usual.
22.
Primary side effect/toxicities associated with local anesthetic use:?
Correct Answer
A. Allergic reactions and systemic toxicity
Explanation
The primary side effects/toxicities associated with local anesthetic use are allergic reactions and systemic toxicity. Allergic reactions can occur in response to the local anesthetic, leading to symptoms such as rash, itching, and difficulty breathing. Systemic toxicity can also occur, where the local anesthetic enters the bloodstream and affects the central nervous system, leading to symptoms such as dizziness, confusion, seizures, and even cardiac arrest.
23.
Factors enhancing bupivacaine (Marcaine) toxicity?
Correct Answer
A. Pregnancy, presence of calcium channel blockers, arterial hypoxemia, acidosis and hypercarbia
Explanation
Bupivacaine (Marcaine) is a local anesthetic that is commonly used for pain relief during childbirth or surgery. However, it can be toxic if excessive amounts are absorbed into the bloodstream. Pregnancy can enhance the toxicity of bupivacaine due to physiological changes that occur during pregnancy, such as increased blood volume and decreased protein binding of the drug. Calcium channel blockers, which are medications used to treat hypertension and certain heart conditions, can also enhance bupivacaine toxicity by inhibiting the metabolism and elimination of the drug. Arterial hypoxemia, which is low oxygen levels in the blood, can decrease the body's ability to metabolize and eliminate bupivacaine, leading to increased toxicity. Acidosis, a condition characterized by increased acidity in the blood, and hypercarbia, elevated levels of carbon dioxide in the blood, can also enhance bupivacaine toxicity by impairing its metabolism and elimination.
24.
Agents added to local anesthetics that prolonged local anesthetic duration of action?
Correct Answer
A. EpinepHrine, pHenylepHrine (Neo-SynepHrine) and dextran
Explanation
Epinephrine, phenylephrine (Neo-Synephrine), and dextran are all agents that can be added to local anesthetics to prolong their duration of action. Epinephrine is a vasoconstrictor that reduces blood flow to the site of administration, thereby slowing down the absorption and metabolism of the local anesthetic. Phenylephrine also acts as a vasoconstrictor and can enhance the effects of the local anesthetic. Dextran is a substance that increases the viscosity of the local anesthetic solution, allowing for a slower release and prolonged effect. Therefore, the addition of these agents can help to extend the duration of action of local anesthetics.
25.
Typically a zone of differential sympathetic nervous system blockade?
Correct Answer
A. Spinal
Explanation
A zone of differential sympathetic nervous system blockade typically occurs with a spinal anesthesia. This type of anesthesia involves injecting medication directly into the cerebrospinal fluid in the spinal canal, which blocks the transmission of nerve signals. As a result, the sympathetic nervous system, which controls involuntary bodily functions such as heart rate and blood pressure, is selectively blocked in the area below the level of the injection. This allows for targeted pain relief and anesthesia in the specific region where the medication is administered.
26.
Preferred local anesthetics for local infiltration:?
Correct Answer
A. Lidocaine (Xylocaine), ropivacaine (Naropin) and bupivacaine (Marcaine)
Explanation
Lidocaine (Xylocaine), ropivacaine (Naropin), and bupivacaine (Marcaine) are all preferred local anesthetics for local infiltration. These medications are commonly used to numb a specific area of the body during minor surgical procedures or dental work. They work by blocking nerve signals in the area, preventing the sensation of pain. Lidocaine is a commonly used local anesthetic due to its fast onset and relatively short duration of action. Ropivacaine and bupivacaine are longer-acting local anesthetics that provide prolonged pain relief. The combination of these three medications offers a range of options for healthcare providers to choose from based on the specific needs of the patient and procedure.
27.
Neurotoxicity associate with local anesthesia: sensory anesthesia, bowell & bladder sphincter dysfunction, paraplegia -- may because by nonhomogeneous local anesthetic distribution?
Correct Answer
A. Cauda equina syndrome
Explanation
Cauda equina syndrome is a condition that occurs when the nerves at the base of the spinal cord, known as the cauda equina, become compressed. This compression can lead to symptoms such as sensory anesthesia, dysfunction of the bowell and bladder sphincters, and even paraplegia. In the context of neurotoxicity associated with local anesthesia, it is possible that the nonhomogeneous distribution of the anesthetic could result in compression of the cauda equina nerves, leading to the development of cauda equina syndrome.
28.
Neurotoxicity -- moderate/severe lower back, buttocks, posterior side pain?
Correct Answer
A. Transient radicular irritation
Explanation
Transient radicular irritation is a condition characterized by moderate to severe pain in the lower back, buttocks, and posterior side. It is caused by irritation of the nerve roots in the spinal cord, often due to trauma or inflammation. This condition is usually temporary and resolves on its own. Cauda equina syndrome, on the other hand, is a more serious condition that involves compression of the nerve roots in the lower spinal cord, resulting in severe lower back pain, weakness, and bladder or bowel dysfunction. Anterior spinal artery syndrome is a rare condition caused by a blockage in the artery supplying blood to the spinal cord, leading to severe pain and paralysis.
29.
Factors that influence lidocaine (Xylocaine) metabolism:?
Correct Answer
A. Pregnancy-induced hypertension, hepatic disease, reduced liver blood flow and volatile anesthetics
Explanation
Lidocaine (Xylocaine) is a medication used for local anesthesia. Its metabolism can be influenced by various factors. Pregnancy-induced hypertension, hepatic disease, reduced liver blood flow, and volatile anesthetics are all factors that can affect the metabolism of lidocaine. Pregnancy-induced hypertension can alter the body's ability to metabolize lidocaine, while hepatic disease can impair liver function and affect lidocaine metabolism. Reduced liver blood flow can also impact the metabolism of lidocaine. Additionally, the presence of volatile anesthetics can interact with lidocaine and affect its metabolism.
30.
Most common cause of toxic plasma local anesthetic concentrations?
Correct Answer
A. Accidental direct intravascular injection during block
Explanation
Accidental direct intravascular injection during a block is the most common cause of toxic plasma local anesthetic concentrations. This occurs when the local anesthetic is inadvertently injected into a blood vessel, leading to rapid absorption into the systemic circulation and potentially toxic levels of the drug in the plasma. This can result in systemic toxicity and adverse effects on the central nervous system, cardiovascular system, and other organ systems. It is important for healthcare professionals to take precautions and use proper techniques to minimize the risk of intravascular injection during local anesthetic administration.
31.
Common eutectic mixture of local anesthetics (EMLA)?
Correct Answer
A. Lidocaine (Xylocaine) and prilocaine (Citanest)
Explanation
The common eutectic mixture of local anesthetics (EMLA) is lidocaine (Xylocaine) and prilocaine (Citanest). This combination is often used as a topical anesthetic to numb the skin before certain medical procedures. Lidocaine is a fast-acting local anesthetic that works by blocking nerve signals in the area where it is applied, while prilocaine helps to enhance the numbing effect. Together, they provide effective pain relief for minor procedures such as needle insertions, skin grafts, and the removal of warts or moles.
32.
Most frequent local anesthetic clinical use:?
Correct Answer
A. Regional anesthetia
Explanation
The correct answer is regional anesthesia. Regional anesthesia refers to the administration of local anesthetic agents to block nerve transmission in a specific region of the body, resulting in loss of sensation and motor function. It is commonly used in surgical procedures to provide pain relief and allow for a pain-free operation. This technique is preferred over general anesthesia in certain cases as it has fewer systemic side effects and allows for faster recovery.
33.
Lidocaine (Xylocaine) effect on ventilation response to hypoxia?
Correct Answer
A. Depressed response
Explanation
Lidocaine, also known as Xylocaine, depresses the response of ventilation to hypoxia. This means that when exposed to low oxygen levels, the body's natural reaction to increase ventilation and oxygen intake is reduced or suppressed when lidocaine is present.
34.
Clinical use(s) of EMLA applications:?
Correct Answer
A. Lumbar puncture
Explanation
EMLA applications are used in clinical settings for various procedures such as lumbar puncture, arterial cannulation, venipuncture, and myringotomy. In this case, the correct answer is lumbar puncture, indicating that EMLA can be applied during this procedure. EMLA is a topical anesthetic cream that contains lidocaine and prilocaine, which helps numb the skin and reduce pain during medical interventions. It is commonly used for procedures that involve needle insertion, such as lumbar puncture, where a needle is inserted into the spinal canal to collect cerebrospinal fluid for diagnostic purposes.
35.
Allergic reactions to local anesthetics:?
Correct Answer
A. High-risk with ester-type agents which are metabolized to p-aminobenzoic acid-related compounds and intradermal testing for possible allergy to local anesthetics should use preservative-free drug
Explanation
Allergic reactions to local anesthetics are more likely to occur with ester-type agents, as they are metabolized to p-aminobenzoic acid-related compounds. Intradermal testing for possible allergy to local anesthetics should use preservative-free drugs to minimize the risk of allergic reactions. Cross-sensitivity between esters and amide-type local anesthetics is also common, further increasing the risk of allergic reactions. Therefore, the statement "high-risk with ester-type agents which are metabolized to p-aminobenzoic acid-related compounds and intradermal testing for possible allergy to local anesthetics should use preservative-free drug" accurately summarizes the information provided.
36.
Factors which increase local anesthetic CNS toxicities:?
Correct Answer
A. Rate of injection, patient receiving mexiletine (Mexitil) when lidocaine (Xylocaine) is used and high PaCO2 (reduced local anesthetic seizure threshold)
Explanation
The factors that increase local anesthetic CNS toxicities are the rate of injection, patient receiving mexiletine (Mexitil) when lidocaine (Xylocaine) is used, and high PaCO2 (reduced local anesthetic seizure threshold).
37.
Least likely to exhibit cross-sensitivity with amide or ester local anesthetics.?
Correct Answer
A. Dyclonine (Dyclone)
Explanation
Dyclonine is least likely to exhibit cross-sensitivity with amide or ester local anesthetics. This means that it is less likely to cause an allergic reaction or sensitivity in individuals who have previously had a reaction to other local anesthetics. Cross-sensitivity occurs when a person has an allergic reaction to one substance and then develops a similar reaction to another substance that is structurally similar. In this case, dyclonine is less structurally similar to amide or ester local anesthetics compared to the other options, making it less likely to cause cross-sensitivity.
38.
Factor(s) that reduce lidocaine (Xylocaine) seizure threshold.?
Correct Answer
A. Hypoxemia, Hyperkalemia and Acidosis
Explanation
Hypoxemia, hyperkalemia, and acidosis are all factors that can reduce the seizure threshold of lidocaine (Xylocaine). Hypoxemia refers to low levels of oxygen in the blood, which can impair brain function and increase the risk of seizures. Hyperkalemia is an elevated level of potassium in the blood, which can disrupt the electrical activity of the brain and make it more prone to seizures. Acidosis is a condition characterized by excessive acidity in the blood, which can also interfere with normal brain function and lower the seizure threshold. Therefore, the presence of any of these factors can increase the likelihood of experiencing seizures when using lidocaine.
39.
Local anesthetic which produces localized vasoconstriction and anesthesia?
Correct Answer
A. cocaine
Explanation
Cocaine is a local anesthetic that produces localized vasoconstriction and anesthesia. It works by blocking the transmission of nerve signals, which leads to numbness and loss of sensation in the area where it is applied. Additionally, cocaine also causes vasoconstriction, which helps to reduce bleeding and prolong the effects of anesthesia.
40.
Agents not recommended for Bier block:
Correct Answer
A. chloroprocaine (Nesacaine), mepivacaine (Carbocaine), and bupivacaine (Marcaine)
41.
Manifestation of systemic toxicity
Correct Answer
A. CNS toxicity, cardiovascular toxicity and neurological symptoms
Explanation
This answer suggests that the manifestation of systemic toxicity can include CNS toxicity, cardiovascular toxicity, and neurological symptoms. This means that when a substance or condition causes toxicity in the body, it can affect the central nervous system, the cardiovascular system, and result in various neurological symptoms.
42.
Most commonly used local anesthetic for rhinolaryngologic cases
Correct Answer
A. Cocaine
Explanation
Cocaine is the most commonly used local anesthetic for rhinolaryngologic cases. This is because it has potent vasoconstrictive properties, which helps in reducing bleeding during the procedure. It also provides effective anesthesia and has a rapid onset of action.
43.
Commonly use local anesthetics for topical/surface application:
Correct Answer
A. Lidocaine (Xylocaine), tetracaine (pontocaine) and cocaine
Explanation
Lidocaine (Xylocaine), tetracaine (Pontocaine), and cocaine are commonly used local anesthetics for topical/surface application. These medications are applied directly to the skin or mucous membranes to numb the area and provide pain relief. Lidocaine and tetracaine are widely used for various procedures, such as minor surgeries, dental work, and dermatological procedures. However, cocaine, although historically used as a local anesthetic, is now primarily a controlled substance due to its potential for abuse and addiction.
44.
Clinical presentations suggestive of local anesthetic allergies:
Correct Answer
A. All are correct
Explanation
All of the listed clinical presentations, including rash, laryngeal edema, bronchospasm, urticaria, and possibly hypotension, are suggestive of local anesthetic allergies. These symptoms can indicate an allergic reaction to the local anesthetic, which can range from mild to severe. It is important to recognize and address these symptoms promptly to prevent any further complications or adverse reactions.
45.
Local anesthetic most likely to cause cyanosis secondary to reduced oxygen transport:
Correct Answer
A. Prilocaine (Citanest)
Explanation
Prilocaine is the most likely local anesthetic to cause cyanosis secondary to reduced oxygen transport. This is because prilocaine has a higher affinity for binding to hemoglobin compared to other local anesthetics. When prilocaine binds to hemoglobin, it reduces the ability of hemoglobin to carry oxygen, leading to a decrease in oxygen transport to tissues. This can result in cyanosis, a bluish discoloration of the skin and mucous membranes due to inadequate oxygenation. Lidocaine, bupivacaine, dibucaine, and procaine have lower affinity for hemoglobin and are less likely to cause cyanosis.
46.
This amide-type local anesthetic is used to assess the possible presence of atypical cholinesterase
Correct Answer
A. Dibucaine (Nupercainal, generic)
Explanation
Dibucaine is an amide-type local anesthetic that is specifically used to assess the possible presence of atypical cholinesterase. Atypical cholinesterase is a genetic variant of the enzyme cholinesterase, which is responsible for breaking down certain medications, including local anesthetics. Dibucaine is used as a diagnostic tool to determine if an individual has this genetic variant, as it produces a different response in individuals with atypical cholinesterase compared to those with normal cholinesterase. Therefore, dibucaine is the correct answer in this case.
47.
Toxicities associated with systemic epinephrine absorption following local anesthetic use with epinephrine included in the local anesthetic solution
Correct Answer
A. Hypertension and Arrhythmias
Explanation
Systemic absorption of epinephrine, which is included in the local anesthetic solution, can lead to toxicities such as hypertension and arrhythmias. Epinephrine is a vasoconstrictor that can cause an increase in blood pressure, leading to hypertension. Additionally, it can affect the electrical conduction system of the heart, resulting in arrhythmias. Therefore, both hypertension and arrhythmias are potential adverse effects associated with systemic epinephrine absorption following local anesthetic use.
48.
Ropivacaine (Naropin):less cardiotoxic then bupivacaine (Marcaine)
Correct Answer
A. True
Explanation
Ropivacaine (Naropin) is indeed less cardiotoxic than bupivacaine (Marcaine). Cardiotoxicity refers to the potential of a drug to cause harm to the heart. Ropivacaine, a local anesthetic, has been found to have a lower risk of causing adverse effects on the cardiovascular system compared to bupivacaine. This makes it a safer option for certain medical procedures where local anesthesia is required.
49.
Factor(s) which determine extent of systemic local anesthetic absorption:
Correct Answer
A. All are not correct
Explanation
The extent of systemic local anesthetic absorption is not determined by any of the factors mentioned in the options. The correct answer implies that factors other than the initial dose, injection site vascularity, intrinsic drug properties, or the use of epinephrine for local vasoconstriction play a role in determining the extent of systemic local anesthetic absorption. The question suggests that there are additional factors that need to be considered.
50.
Lidocaine (Xylocaine) cardiotoxicity -- electrophysiological characteristics
Correct Answer
A. All are not correct
Explanation
The given answer states that all of the given options are incorrect. This means that ECG - PR interval prolongation, increased conduction velocity, reduced phase 4 depolarization, and reduced automaticity are not electrophysiological characteristics of lidocaine (Xylocaine) cardiotoxicity. However, without further information or context, it is not possible to provide a more detailed explanation.