Heparin Dosing And Indications Quiz! Trivia
Explore the pharmacological aspects of Heparin, including its drug category, mechanism of action, main uses, and differences from LMWH.
- 1.
What category of drug does Heparin belong to?
- A.
Anticoagulant
- B.
Haematologic drug
- C.
Haematologic drug + anticoagulant
- D.
NSAIDS
- E.
Antipsychotic
Correct Answer
C. Haematologic drug + anticoagulantExplanation
Heparin belongs to the category of drugs known as haematologic drugs + anticoagulants. This is because Heparin is a medication that is commonly used as an anticoagulant, meaning it prevents the formation of blood clots. Additionally, Heparin is also classified as a haematologic drug because it is used to treat and prevent various disorders related to the blood and blood vessels.Rate this question:
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- 2.
Which coagulation factors are inactivated by Heparin?
- A.
Factor X
- B.
FActor Xa, IXa IIa, XIa, XIIa =multisites of coag pathway + neutralises thromboplastin (factor III)
- C.
Antithrombin
- D.
Factor VII
- E.
FActor XIII
Correct Answer
B. FActor Xa, IXa IIa, XIa, XIIa =multisites of coag pathway + neutralises thromboplastin (factor III)Explanation
Heparin inactivates Factor Xa, IXa, IIa, XIa, and XIIa, which are multiple sites in the coagulation pathway. Additionally, it neutralizes thromboplastin (Factor III).Rate this question:
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- 3.
Heparin is with activity by inactivating factor and inhibiting the conversion of to . Also further activates thrombin preventing the conversion of fibrinogen to . Finally heparin also stops the formation of a stable fibrin clot by inhibiting the activation of
Correct Answer
naturally occuring mucopolysaccharide, anticoagulant, X, prothrombin, thrombin, fibrin, fibrin stabilising factorExplanation
Heparin is a naturally occurring mucopolysaccharide with anticoagulant activity. It works by inactivating factor X and inhibiting the conversion of prothrombin to thrombin. Additionally, heparin further activates thrombin, preventing the conversion of fibrinogen to fibrin. Lastly, heparin inhibits the activation of fibrin stabilizing factor, thereby stopping the formation of a stable fibrin clot.Rate this question:
- 4.
What are the major indications for the use of Heparin?
- 5.
What's the main difference with LMWH?
- A.
Different action to normal heparin
- B.
Longer half life
- C.
Given to outpatients only
- D.
Longer half life and often given to outpatients + pts require lower doses
- E.
More potent then normal heparin
Correct Answer
D. Longer half life and often given to outpatients + pts require lower dosesExplanation
LMWH (Low Molecular Weight Heparin) has a longer half-life compared to normal heparin. This means that it stays in the body for a longer duration, allowing for less frequent dosing. Additionally, LMWH is often given to outpatients, meaning that patients can administer the medication themselves at home rather than requiring hospitalization. Moreover, LMWH requires lower doses compared to normal heparin due to its increased potency.Rate this question:
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- 6.
What is the principal anticoagulant action of heparin?
- A.
Binds factors IIA, IXa + Xa
- B.
Binds to factor X
- C.
Binds to antithrombin III
- D.
Binds to fibrin
- E.
Inhibits platelet aggregation
Correct Answer
C. Binds to antithrombin IIIExplanation
Heparin's principal anticoagulant action is binding to antithrombin III. Antithrombin III is a natural anticoagulant protein in the body that inhibits the activity of several blood clotting factors, including factors IIa, IXa, and Xa. By binding to antithrombin III, heparin enhances its inhibitory effect on these clotting factors, preventing the formation of blood clots.Rate this question:
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Current Version
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Sep 05, 2024Quiz Edited by
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Mar 21, 2009Quiz Created by
Mez
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