Heparin Dosing And Indications Quiz! Trivia

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Mez

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Quizzes Created: 1 | Total Attempts: 556

Questions: 6 | Attempts: 556 | Updated: Sep 5, 2024

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Questions and Answers

1.

What category of drug does Heparin belong to?
- A.
  
  Anticoagulant
- B.
  
  Haematologic drug
- C.
  
  Haematologic drug + anticoagulant
- D.
  
  NSAIDS
- E.
  
  Antipsychotic
Correct Answer
C. Haematologic drug + anticoagulant

Explanation
Heparin belongs to the category of drugs known as haematologic drugs + anticoagulants. This is because Heparin is a medication that is commonly used as an anticoagulant, meaning it prevents the formation of blood clots. Additionally, Heparin is also classified as a haematologic drug because it is used to treat and prevent various disorders related to the blood and blood vessels.

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2.

Which coagulation factors are inactivated by Heparin?
- A.
  
  Factor X
- B.
  
  FActor Xa, IXa IIa, XIa, XIIa =multisites of coag pathway + neutralises thromboplastin (factor III)
- C.
  
  Antithrombin
- D.
  
  Factor VII
- E.
  
  FActor XIII
Correct Answer
B. FActor Xa, IXa IIa, XIa, XIIa =multisites of coag pathway + neutralises thromboplastin (factor III)

Explanation
Heparin inactivates Factor Xa, IXa, IIa, XIa, and XIIa, which are multiple sites in the coagulation pathway. Additionally, it neutralizes thromboplastin (Factor III).

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3.

Heparin is with activity by inactivating factor and inhibiting the conversion of to . Also further activates thrombin preventing the conversion of fibrinogen to . Finally heparin also stops the formation of a stable fibrin clot by inhibiting the activation of

Correct Answer
naturally occuring mucopolysaccharide, anticoagulant, X, prothrombin, thrombin, fibrin, fibrin stabilising factor

Explanation
Heparin is a naturally occurring mucopolysaccharide with anticoagulant activity. It works by inactivating factor X and inhibiting the conversion of prothrombin to thrombin. Additionally, heparin further activates thrombin, preventing the conversion of fibrinogen to fibrin. Lastly, heparin inhibits the activation of fibrin stabilizing factor, thereby stopping the formation of a stable fibrin clot.

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4
4.

What are the major indications for the use of Heparin?
5.

What's the main difference with LMWH?
- A.
  
  Different action to normal heparin
- B.
  
  Longer half life
- C.
  
  Given to outpatients only
- D.
  
  Longer half life and often given to outpatients + pts require lower doses
- E.
  
  More potent then normal heparin
Correct Answer
D. Longer half life and often given to outpatients + pts require lower doses

Explanation
LMWH (Low Molecular Weight Heparin) has a longer half-life compared to normal heparin. This means that it stays in the body for a longer duration, allowing for less frequent dosing. Additionally, LMWH is often given to outpatients, meaning that patients can administer the medication themselves at home rather than requiring hospitalization. Moreover, LMWH requires lower doses compared to normal heparin due to its increased potency.

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1
0
6.

What is the principal anticoagulant action of heparin?
- A.
  
  Binds factors IIA, IXa + Xa
- B.
  
  Binds to factor X
- C.
  
  Binds to antithrombin III
- D.
  
  Binds to fibrin
- E.
  
  Inhibits platelet aggregation
Correct Answer
C. Binds to antithrombin III

Explanation
Heparin's principal anticoagulant action is binding to antithrombin III. Antithrombin III is a natural anticoagulant protein in the body that inhibits the activity of several blood clotting factors, including factors IIa, IXa, and Xa. By binding to antithrombin III, heparin enhances its inhibitory effect on these clotting factors, preventing the formation of blood clots.

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Current Version
Sep 05, 2024

Quiz Edited by
ProProfs Editorial Team
Mar 21, 2009

Quiz Created by
Mez

Heparin Dosing And Indications Quiz! Trivia

What category of drug does Heparin belong to?

Which coagulation factors are inactivated by Heparin?

Heparin is with activity by inactivating factor and inhibiting the conversion of to . Also further activates thrombin preventing the conversion of fibrinogen to . Finally heparin also stops the formation of a stable fibrin clot by inhibiting the activation of

What are the major indications for the use of Heparin?

What's the main difference with LMWH?

What is the principal anticoagulant action of heparin?