Insulin - High Yield Topic
- 1.
Hyperinsulinemia is seen in Type 2 diabetes
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Insulin resistance leads to more production of insulin.Rate this question:
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- 2.
Who discovered the primary structure of insulin ?
- A.
Karry B mullis
- B.
Hoffman
- C.
Sanger
- D.
Banting & Best
Correct Answer
C. SangerExplanation
Banting & Best discovered insulin. Karry B mullis developed PCR.Rate this question:
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- 3.
The so called "Honeymoon phase" is seen in
- A.
Type I DM
- B.
Type II DM
- C.
Both
- D.
None
Correct Answer
A. Type I DMExplanation
Honeymoon phase is requirement of less exogenous insulin in type I DM.Rate this question:
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- 4.
True about somogyi effect
- A.
Due to secretion of counter-regulatory hormones
- B.
Dose of insulin has to be raised
- C.
Rebound hyperglycemia
- D.
None
Correct Answer
C. Rebound hyperglycemiaExplanation
Rebound hyperglycemia is a true statement about the Somogyi effect. This phenomenon occurs when there is a rapid drop in blood sugar levels during the night, leading to the release of counter-regulatory hormones such as glucagon, cortisol, and growth hormone. These hormones stimulate the liver to produce glucose, causing a rebound increase in blood sugar levels. As a result, the dose of insulin may need to be raised to prevent further episodes of rebound hyperglycemia.Rate this question:
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- 5.
Number of amino acids in Insulin
- A.
83
- B.
71
- C.
61
- D.
51
Correct Answer
D. 51Explanation
Insulin is a peptide hormone composed of two polypeptide chains, an A chain and a B chain, linked by disulfide bonds. The A chain has 21 amino acids, while the B chain has 30 amino acids. Therefore, the total number of amino acids in insulin is 51.Rate this question:
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- 6.
Which is NOT an ultra short acting insulin
- A.
Lispro
- B.
Aspart
- C.
Glargine
- D.
Glulisine
Correct Answer
C. GlargineExplanation
Glargine is not an ultra short acting insulin. It is actually a long-acting insulin that provides a steady level of insulin in the body over a longer period of time. Ultra short acting insulins, such as Lispro, Aspart, and Glulisine, have a rapid onset of action and are used to control blood sugar levels during meals. Glargine, on the other hand, is used to provide a basal level of insulin throughout the day and night.Rate this question:
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- 7.
Which is not a non-diabetic use of insulin
- A.
Hypokalemia
- B.
Hyperkalemia
- C.
Anterior pituitary assesment
- D.
Assessment of completeness of truncal vagotomy
Correct Answer
A. HypokalemiaExplanation
Insulin is not used for the treatment of hypokalemia. Hypokalemia is a condition characterized by low levels of potassium in the blood. Insulin is primarily used to manage diabetes by helping to regulate blood sugar levels. It works by facilitating the uptake of glucose into cells, thereby lowering blood glucose levels. In the context of hypokalemia, other treatments such as potassium supplements or changes in diet may be used to address the low potassium levels.Rate this question:
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- 8.
Insulin dependent glucose uptake happens in
- A.
Muscles
- B.
Liver
- C.
Pancreatic beta cells
- D.
None
Correct Answer
A. MusclesExplanation
Insulin is a hormone that regulates glucose uptake in the body. In the case of insulin-dependent glucose uptake, it occurs in muscles. When insulin is released into the bloodstream, it binds to receptors on muscle cells, allowing glucose to enter the cells and be used for energy. This process is essential for maintaining normal blood sugar levels and providing energy for muscle contraction and movement.Rate this question:
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- 9.
Select the FALSE statement
- A.
Insulin induces glucokinase
- B.
Insulin releasing action by oral of glucose is higher than the same amount of iv glucose
- C.
Insulin inhibits lipoprotein lipase
- D.
None
Correct Answer
C. Insulin inhibits lipoprotein lipaseExplanation
Reason for the second option is release of incretins.Rate this question:
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- 10.
Gold standard method for measurement of insulin resistance
- A.
HOMA-IR
- B.
Frequently sampled IGTT
- C.
Adiponectin assay
- D.
Euglycemic clamp
Correct Answer
D. Euglycemic clampExplanation
The euglycemic clamp is considered the gold standard method for measuring insulin resistance. This method involves infusing insulin into the bloodstream at a constant rate to maintain a stable blood glucose level. By measuring the amount of glucose needed to maintain this stable level, the body's response to insulin can be assessed. This method provides a direct and accurate measurement of insulin resistance and is commonly used in research and clinical settings.Rate this question:
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Current Version
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Mar 20, 2023Quiz Edited by
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May 19, 2015Quiz Created by
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