1.
A typical NIH grant provides money for a ________ year period
Correct Answer
C. Three
Explanation
A typical NIH grant provides money for a three-year period. This means that the grant recipient will receive funding for their research project for a duration of three years. During this time, they can utilize the funds to conduct their research, collect data, and make progress towards their scientific goals. The three-year period allows researchers to have a sufficient amount of time to carry out their studies and potentially make significant contributions to their field of study.
2.
The primary ganting agency through which the untied states conducts and supports biomedical research is the
Correct Answer
B. NIH
Explanation
The primary funding agency through which the United States conducts and supports biomedical research is the National Institutes of Health (NIH). The NIH is a part of the U.S. Department of Health and Human Services and is responsible for funding and conducting research aimed at improving public health and reducing the burden of disease. The NIH provides financial support for various research projects, including basic, clinical, and translational research, as well as training and career development programs for researchers. It is composed of 27 institutes and centers, each focused on specific areas of health and disease, such as cancer, heart disease, neurological disorders, and infectious diseases. By funding cutting-edge biomedical research, the NIH plays a vital role in advancing our understanding of human health and developing new treatments and interventions for a wide range of medical conditions.
3.
The Guide for the care and use of Agricultural Animals in Agricultural Research and teaching focuses on the humane care of animals used in production agriculture. What type of animals are excluded from this publication ?
Correct Answer
A. Animals used in biomedical research and teaching
Explanation
The Guide for the care and use of Agricultural Animals in Agricultural Research and teaching focuses on the humane care of animals used in production agriculture. This means that it does not cover animals used in biomedical research and teaching, as they have different requirements and considerations. The publication instead focuses on animals used for food and fiber research, as well as equine animals.
4.
What agency is responsible for determining whether new medical devices (like artificial joints and cardiac pacemakers) are safe and effective befroe they are approved for sale in the United States?
Correct Answer
D. Food and Drug Administration
Explanation
The Food and Drug Administration (FDA) is responsible for determining whether new medical devices, such as artificial joints and cardiac pacemakers, are safe and effective before they are approved for sale in the United States. The FDA is a government agency that regulates and oversees the safety and efficacy of drugs, medical devices, food, cosmetics, and other products. They conduct rigorous testing and review processes to ensure that medical devices meet the necessary standards before they can be sold to the public.
5.
The IACUC ___________
Correct Answer
D. All above
Explanation
The IACUC (Institutional Animal Care and Use Committee) is responsible for reviewing animal use protocols, conducting inspections of animal facilities, and reviewing institutional animal use programs every six months. Additionally, the IACUC can serve as an information and resource liaison on animal welfare and research concerns.
6.
AAALAC International __________________. (identify the false statement)
Correct Answer
B. Is a goverment sponsored agency
Explanation
AAALAC International is not a government-sponsored agency. It is a private, nonprofit organization that provides voluntary accreditation for animal care and use programs. It conducts site visits every three years and requires annual reports from its accredited facilities.
7.
Research institutions provide The Public Health Service with a signed agreement that outlines the institution complies with all aspects of human animal care as described in the pHS Policy. This agreement is called the _____________Assurance
Correct Answer
B. Animal Welfare
Explanation
Research institutions provide The Public Health Service with a signed agreement that outlines the institution complies with all aspects of human animal care as described in the PHS Policy. This agreement is called the Animal Welfare Assurance.
8.
If animals are to be euthanized at the end of the study, the method of euthanasia must be in accordance with the guidlines (Panel on Euthanasia set up by the___________.
Correct Answer
C. AVMA
Explanation
The correct answer is AVMA (American Veterinary Medical Association). The AVMA is an organization that provides guidelines and standards for the humane euthanasia of animals. They have a panel specifically dedicated to euthanasia and provide recommendations on the appropriate methods to be used.
9.
The IACUC must conduct inspections of the animals facilities and support areas at least one every ________months
Correct Answer
B. Six
Explanation
The IACUC must conduct inspections of the animal facilities and support areas at least once every six months. This ensures regular monitoring and evaluation of the conditions and welfare of the animals. Conducting inspections every three months would be too frequent, while inspections every twelve or twenty-four months would not provide adequate oversight. Therefore, the correct answer is six months.
10.
The animal census is a ________
Correct Answer
B. Method of record keeeping
Explanation
The animal census is a method of record keeping. This means that it is a system or process used to document and maintain information about animals. A census involves counting and collecting data about a population, in this case, animals. By conducting an animal census, information such as population size, species distribution, and other relevant data can be recorded and used for various purposes such as conservation, research, and management.
11.
Per diem cost are the expense required to maintain one animal for _____________
Correct Answer
C. One day
Explanation
Per diem costs refer to the daily expenses required to maintain one animal. This means that the cost is calculated on a daily basis, regardless of the duration of time the animal is maintained in the facility. Therefore, the correct answer is "one day."
12.
If it costs $6000.00 per year to maintian 200 rats, what should the per diem be?
Correct Answer
A. .08
Explanation
The per diem should be .08 because it is the correct answer that satisfies the given information. The question states that it costs $6000.00 per year to maintain 200 rats. To find the per diem, we need to divide the total cost by the number of rats. $6000.00 divided by 200 rats equals $30.00 per rat per year. To find the per diem, we need to divide $30.00 by 365 days. This equals approximately .08, which is the correct answer.
13.
An institution where each department keeps and uses animals in its own animal facility using its own operating budget is___________
Correct Answer
B. Decentralized
Explanation
Decentralized is the correct answer because in this type of institution, each department has its own animal facility and operates independently with its own budget. This means that decision-making and control over the animals are distributed among the different departments, rather than being centralized in one central authority.
14.
USDA identification tags for dogs and cats must be retained for ___ year(s) for possible review by a USDA inspector
Correct Answer
A. One
Explanation
USDA identification tags for dogs and cats must be retained for one year for possible review by a USDA inspector. This means that pet owners should keep the tags on their pets for a period of one year in case a USDA inspector wants to examine them. It is important to retain these tags as they serve as proof of compliance with USDA regulations and can be used to ensure the health and safety of the animals.
15.
The pHS Policy requires that all assurance records related directly to grant applications, research proposals and changes in research activites be maintianed for at least _____year(s) after complection of an activity
Correct Answer
C. Three
Explanation
The PHS Policy mandates the maintenance of assurance records for a specific period after the completion of an activity. In this case, the correct answer is "three," indicating that these records must be kept for at least three years. This requirement ensures that there is a sufficient record of grant applications, research proposals, and changes in research activities for future reference and potential audits.
16.
The total blood volume in an animal's body equals approximately _________% of its body weight
Correct Answer
B. 6
Explanation
The total blood volume in an animal's body is approximately 6% of its body weight. This means that for every kilogram of an animal's body weight, around 60 milliliters of blood is present. Blood volume is an important factor in maintaining homeostasis and ensuring proper oxygen and nutrient transport throughout the body.
17.
A rabbit has a total blood volume percentage of 6%. What would be the total blood volume for a rabbit weighing 3 kilograms?
Correct Answer
C. 180 ml
Explanation
To calculate the total blood volume for a 3kg rabbit with a blood volume percentage of 6%:
Total blood volume = (Weight of the rabbit in kg) × (Blood volume percentage)
Total blood volume = 3 kg × 6% = 3 kg × 0.06 = 0.18 kg
Now, we need to convert the blood volume from kilograms to milliliters.
Since 1 kg = 1000 grams and 1 gram = 1 milliliter for water:
Total blood volume = 0.18 kg × 1000 ml/kg = 180 ml
So, the total blood volume for a 3kg rabbit would be 180 ml.
Therefore, the correct answer is 180 ml.
18.
Identify the route of injection that provides the fatest abosrbtion into the body system
Correct Answer
D. I.V.
Explanation
The route of injection that provides the fastest absorption into the body system is intravenous (I.V.) injection. This method involves injecting the substance directly into a vein, allowing it to quickly enter the bloodstream and be distributed throughout the body. Compared to other routes such as intraperitoneal (I.P.), subcutaneous (S.C.), and intradermal (I.D.) injections, the I.V. route provides the most immediate and efficient absorption.
19.
The gauge of the needle refers to the ________
Correct Answer
B. Diameter
Explanation
The gauge of the needle refers to its diameter. The gauge is a standardized measurement that indicates the size of the needle's opening. A smaller gauge number corresponds to a larger needle diameter, while a larger gauge number corresponds to a smaller needle diameter. The gauge of the needle is an important factor to consider when choosing the appropriate needle for a specific medical procedure or injection.
20.
The most desirable site for an IM injection is _________
Correct Answer
B. A large muscle mass
Explanation
The most desirable site for an IM injection is a large muscle mass because it allows for better absorption and distribution of the medication. A large muscle mass has a greater blood supply, which helps in the efficient delivery of the medication to the bloodstream. It also reduces the risk of damage to surrounding structures and nerves. Additionally, injecting into a large muscle mass ensures that the medication is not injected into a joint or a blood vessel, which could cause complications.
21.
When giving an intramuscular injection in the hind limb, care must be taken to avoid what structures
Correct Answer
D. All of the above
Explanation
When giving an intramuscular injection in the hind limb, care must be taken to avoid the femoral vein, femoral artery, and femoral nerve. These structures are all located in the hind limb and can be damaged if not avoided during the injection. Damage to the femoral vein can lead to bleeding, damage to the femoral artery can result in significant bleeding, and damage to the femoral nerve can cause pain and loss of function in the limb. Therefore, it is important to be cautious and avoid all of these structures when administering an intramuscular injection in the hind limb.
22.
Which part of the mouse model BALB/c StCrl p GF (F83) is the strain symbol?
Correct Answer
C. BALB
Explanation
The strain symbol in the mouse model BALB/c StCrl p GF (F83) is BALB.
23.
The receptive stance (fixed position with hindquarters elevated and tail to one side) of the female in estrus is known as ___________.
Correct Answer
B. Lordosis
Explanation
The receptive stance of the female in estrus, characterized by a fixed position with hindquarters elevated and tail to one side, is known as lordosis. This is a natural behavior displayed by female mammals during their fertile period to signal their readiness to mate. Hyperkaratosis refers to the thickening of the skin, anestrus is a period of sexual inactivity, and follicular stimulation involves the growth and development of ovarian follicles.
24.
Of four stages of estrus which is defined as that where follicle development takes place?
Correct Answer
D. Proestrus
Explanation
Proestrus is the stage of estrus where follicle development takes place. During this stage, the follicles in the ovaries start to develop and mature, preparing for ovulation. This is the initial phase of the estrus cycle and is characterized by an increase in estrogen levels, which leads to the development of a receptive uterus and the onset of behavioral changes in the female.
25.
Which of the following lab animal spcies does not prodice a good model for polygamous mating systems
Correct Answer
D. Gerbils
Explanation
Gerbils do not produce a good model for polygamous mating systems because they are monogamous animals, meaning they form long-term pair bonds with a single partner. In polygamous mating systems, individuals have multiple mates, which is not the case for gerbils. Therefore, gerbils would not be suitable for studying the dynamics and behaviors associated with polygamous mating systems.
26.
The addition of a male to a cage which has held only females, resulting in the initiation of estrus in the females at about three days is known as ________
Correct Answer
B. The Whitten effect
Explanation
The Whitten effect refers to the phenomenon where the addition of a male to a cage that previously only housed females leads to the initiation of estrus in the females after approximately three days. This effect is commonly observed in rodent studies and is believed to be triggered by the presence of male pheromones, which synchronize the reproductive cycles of the females. This synchronization can increase the chances of successful mating and reproduction in the group.
27.
Mice that have had DNA from a different animal inserted into thier genes are termed______
Correct Answer
B. Transgenic
Explanation
Mice that have had DNA from a different animal inserted into their genes are termed "transgenic". This term is used to describe organisms that have had genetic material from another species introduced into their own genetic makeup. In the case of these mice, their DNA has been altered to include genes from a different animal, making them transgenic.
28.
The integumentary system is comprised of _______
Correct Answer
B. Skin
Explanation
The integumentary system is comprised of the skin. The skin is the largest organ of the body and is responsible for protecting the underlying tissues and organs, regulating body temperature, and sensing touch, pressure, and pain. It also helps in the production of vitamin D and plays a role in the immune system by acting as a barrier against pathogens.
29.
Platelets are essential for _______
Correct Answer
B. Clotting blood
Explanation
Platelets are essential for clotting blood because they play a crucial role in the formation of blood clots. When a blood vessel is damaged, platelets are activated and aggregate at the site of injury to form a clot, which helps to stop bleeding. Platelets release various clotting factors that initiate a cascade of reactions leading to the formation of fibrin, a protein that forms a mesh-like structure to reinforce the clot. Without platelets, the body would have difficulty in controlling bleeding, leading to excessive blood loss and potential life-threatening situations.
30.
All mammals have a_____ chambered heart
Correct Answer
C. Four
Explanation
The statement "All mammals have a four-chambered heart" is a well-known fact in biology. Mammals, including humans, have a four-chambered heart consisting of two atria and two ventricles. This four-chambered structure allows for efficient separation of oxygenated and deoxygenated blood, ensuring proper circulation throughout the body.
31.
The left ventricle contracts, pumping blood to _______
Correct Answer
D. All the organs of the body
Explanation
The left ventricle is responsible for pumping oxygenated blood to all the organs of the body. This is because the left ventricle receives oxygen-rich blood from the lungs and then contracts to propel this oxygenated blood into the aorta, which is the largest artery in the body. From the aorta, the oxygenated blood is distributed to all the organs and tissues, ensuring that they receive the necessary oxygen and nutrients for proper functioning. Therefore, the correct answer is all the organs of the body.
32.
Oxygen and carbon dioxide are exchanged between the blood and the air in what anatomical structure of the lungs ?
Correct Answer
C. Alveoli
Explanation
Oxygen and carbon dioxide are exchanged between the blood and the air in the alveoli of the lungs. The alveoli are small air sacs located at the end of the bronchioles. They have thin walls and a large surface area, allowing for efficient gas exchange. Oxygen from the air diffuses into the bloodstream, while carbon dioxide, a waste product, diffuses out of the bloodstream into the alveoli to be exhaled. The bronchi, trachea, and bronchioles are all part of the respiratory system, but the actual exchange of gases occurs in the alveoli.
33.
Sexual reproduction is conrolled by __________.
Correct Answer
D. All of the above
Explanation
Sexual reproduction is a complex process that involves the coordination of various hormones and chemicals in the body. These hormones, such as estrogen and testosterone, play a crucial role in regulating the development and functioning of the reproductive organs. The pituitary gland, often referred to as the "master gland," releases hormones that stimulate the gonads (ovaries in females and testes in males) to produce sex hormones. Therefore, all of the options mentioned - hormones, chemicals in the body, pituitary gland, and gonads - are correct as they are all involved in controlling sexual reproduction.
34.
In goats, cattle, and sheep the breakdown of cellulose occurs _____________.
Correct Answer
C. In the ruman
Explanation
In goats, cattle, and sheep, the breakdown of cellulose occurs in the rumen. The rumen is the first compartment of their multi-chambered stomach, where microbial fermentation takes place. This fermentation process allows the animals to break down cellulose, a complex carbohydrate found in plant cell walls, with the help of microorganisms such as bacteria and protozoa. The breakdown of cellulose in the rumen is essential for these animals to obtain nutrients from plant material and is a crucial step in their digestive process.
35.
Respiration ____________.
Correct Answer
D. All of the above
Explanation
The correct answer is "all of the above". Respiration is a process that involves the exchange of gases between an organism and its environment. It can occur in various organs such as the lungs and gills. Additionally, respiration is a mechanical process that relies on pressure gradients between tissues and blood. Therefore, all of the given statements are true and encompass the concept of respiration.
36.
The lymphatic system _________________
Correct Answer
A. Regulates fluid balance between tissue and blood plasma
Explanation
The lymphatic system is responsible for regulating fluid balance between tissue and blood plasma. It helps to maintain the proper balance of fluids in the body by collecting excess fluid from the tissues and returning it to the bloodstream. This helps to prevent the accumulation of fluid and swelling in the tissues. Additionally, the lymphatic system plays a role in immune function by filtering and removing waste, toxins, and pathogens from the body.
37.
How often should you clean automatic waterers, bottles, feeders, and buckets?
Correct Answer
C. Once a week
Explanation
Automatic waterers, bottles, feeders, and buckets should be cleaned once a week. Regular cleaning is important to prevent the buildup of bacteria, algae, and other contaminants that can affect the quality of the water and feed. Cleaning them once a week ensures that they remain hygienic and safe for the animals to use.
38.
How often should you clean dog and other large animals cages or stalls ?
Correct Answer
A. Daily
Explanation
Daily cleaning of dog and other large animal cages or stalls is necessary to maintain their hygiene and prevent the buildup of waste, bacteria, and odors. Animals produce waste regularly, and leaving it uncleaned for longer periods can lead to health issues and discomfort for the animals. Daily cleaning also helps to ensure a clean and safe environment for both the animals and their caretakers.
39.
How often should you clean wire bottom cages ?
Correct Answer
D. Once every two weeks
Explanation
Wire bottom cages should be cleaned once every two weeks. This is because wire bottom cages allow waste to fall through the wire and accumulate in a tray underneath. Cleaning the cage once every two weeks ensures that the waste does not build up too much, maintaining a clean and hygienic living environment for the animal. Cleaning more frequently, such as daily or twice a week, may not be necessary and could cause unnecessary stress to the animal.
40.
How often should you clean bedded cages ?
Correct Answer
C. Once a week
Explanation
Bedded cages should be cleaned once a week to maintain cleanliness and hygiene for the animals. Cleaning the cages on a regular basis helps to remove waste, odors, and potential sources of infection. It also ensures that the animals have a clean and comfortable living environment. Cleaning the cages more frequently, such as daily or twice a week, may be excessive and unnecessary, while cleaning them less frequently, such as once every two weeks, may lead to unsanitary conditions for the animals. Therefore, cleaning bedded cages once a week strikes a balance between maintaining cleanliness and minimizing stress for the animals.
41.
Which of the following will prevent cross-contamination within a facility ?
Correct Answer
D. All of the above are correct
Explanation
Wearing protective clothing, separating quarantine animals from study animals, and disinfecting equipment are all measures that can prevent cross-contamination within a facility. Wearing protective clothing, such as gloves and lab coats, can prevent the transfer of contaminants from one area to another. Separating quarantine animals from study animals ensures that any potential pathogens or diseases are contained and do not spread to healthy animals. Disinfecting equipment regularly helps to kill any bacteria or viruses that may be present, reducing the risk of contamination. Therefore, all of the above options are correct in preventing cross-contamination within a facility.
42.
A condition in rodents caused by high temperaturs and low relative humidity is __________
Correct Answer
D. Ring tail
Explanation
Ring tail is a condition in rodents that is caused by high temperatures and low relative humidity. This condition affects the tail of the rodent, causing it to become dry, brittle, and develop a ring-like appearance. This can lead to discomfort and potential health issues for the rodent.
43.
HEPA filters are only efficient in removing up to _______________of particulate matter.
Correct Answer
D. 99.7%
Explanation
HEPA filters are highly efficient in removing particulate matter from the air. The given answer of 99.7% suggests that these filters can remove almost all of the particulate matter present in the air, leaving only a very small fraction behind. This high level of efficiency makes HEPA filters a popular choice for air purifiers and HVAC systems in order to improve indoor air quality and reduce the risk of respiratory problems caused by airborne pollutants.
44.
Which of the following are methods of setrilization ?
Correct Answer
E. All of the above
Explanation
All of the methods mentioned - chemical, dry heat, moist heat, and radiation - are valid methods of sterilization. Chemical sterilization involves the use of chemicals to kill microorganisms, dry heat sterilization involves the use of high temperatures in an oven or hot air, moist heat sterilization involves the use of steam under pressure, and radiation sterilization involves the use of ionizing radiation to kill microorganisms. Therefore, all of the methods listed are viable options for sterilization.
45.
Animals species that may require higher temperatures than that recommended for rodents and rabbits would include ________.
Correct Answer
A. Pigeons, chickens, and alligators
Explanation
Animals such as pigeons, chickens, and alligators are likely to require higher temperatures than what is recommended for rodents and rabbits. This could be due to their natural habitat and physiological needs. Pigeons and chickens are birds that typically require warmer environments, while alligators are reptiles that are adapted to warmer climates. These animals may have different temperature requirements for optimal health and functioning compared to rodents and rabbits.
46.
The recommended temperature ranges for secondary enclosures for most laboratory species is 19-26 degrees Celsius. This translates to __________________degrees Fahrenheit.
Correct Answer
C. 66-79
Explanation
The recommended temperature range for secondary enclosures for most laboratory species is 19-26 degrees Celsius. To convert this to Fahrenheit, we can use the formula F = (C * 9/5) + 32. By plugging in the values, we get 66-79 degrees Fahrenheit.
47.
The most information about temperature in a secondary enclsoure of animal facility is generated from a ________________.
Correct Answer
C. Minimum/maximum thermomter
Explanation
A minimum/maximum thermometer is the most suitable instrument for generating the most information about temperature in a secondary enclosure of an animal facility. This type of thermometer records both the lowest and highest temperatures reached over a specific period, providing a comprehensive understanding of temperature fluctuations. An anemometer measures wind speed, a hygrometer measures humidity, and a standard thermometer only provides a current temperature reading.
48.
A health care concept often used in laboratory animal medicicne is __________________management.
Correct Answer
B. Herd health
Explanation
Herd health is the correct answer because it is a health care concept commonly used in laboratory animal medicine. It refers to the overall health and well-being of a group or population of animals, rather than focusing on individual animals. This concept is important in laboratory animal medicine as it helps to monitor and manage the health of a group of animals, ensuring their welfare and preventing the spread of diseases within the population.
49.
Minimum of ____ hours is required for rodents to recover from the stress of shipment.
Correct Answer
E. None of the above
Explanation
The question asks for the minimum number of hours required for rodents to recover from the stress of shipment. However, none of the given options provide a specific number of hours. Therefore, the correct answer is "none of the above" as there is no option that accurately represents the minimum recovery time for rodents after shipment stress.
50.
In what order should these species be attended to?
Correct Answer
A. Guinea pig, rabbit
Explanation
The correct order in which these species should be attended to is guinea pig first and then rabbit. This is because each species has its own specific care requirements and attending to the guinea pig first ensures that its needs are met before moving on to the rabbit. Additionally, transitioning from one species to another without proper care and preparation can be stressful for both animals.