1.
Agents that kill bacteria are said to be
Correct Answer
B. Bacteriocidal
Explanation
Bacteriocidal agents are substances that are capable of killing bacteria. They directly target and destroy bacterial cells, leading to their death. Inhibitory agents, on the other hand, may not necessarily kill bacteria but rather prevent their growth or reproduction. Bacteriostatic agents inhibit the growth of bacteria, but do not necessarily kill them. Therefore, the correct answer is "bacteriocidal" because it specifically refers to agents that kill bacteria.
2.
The complete elimination of all microorganisms, including viruses, is called
Correct Answer
B. Sterilization
Explanation
Sterilization refers to the complete elimination of all microorganisms, including viruses. It is a process that ensures the complete destruction or removal of all forms of microbial life, including spores. Disinfection, on the other hand, refers to the reduction of microbial populations to a level that is considered safe for public health. Decontamination is a broader term that includes both sterilization and disinfection, depending on the circumstances. Therefore, in this case, the correct answer is sterilization because it specifically mentions the complete elimination of all microorganisms, including viruses.
3.
The process by which macromolecules lose their structure and ability to function is called
Correct Answer
A. Denaturation
Explanation
Denaturation refers to the process by which macromolecules, such as proteins, lose their structure and ability to function. This can occur due to various factors such as heat, pH changes, or exposure to certain chemicals. Denaturation disrupts the bonds and interactions that maintain the protein's specific structure, causing it to unfold and lose its functional properties. Sterilization refers to the process of killing or removing all forms of microbial life, while thermal death refers to the temperature at which all microorganisms in a particular sample are killed. Therefore, neither sterilization nor thermal death accurately describe the process of macromolecules losing their structure and function.
4.
Which statement is true about heat sterilization?
Correct Answer
D. All of the above are true.
Explanation
All of the statements are true about heat sterilization. Microbial death is indeed more rapid at acidic pH, high concentrations of sugars and salts do influence sterilization time, and the amount of water in a substance is indeed a major factor in heat resistance. Therefore, the correct answer is that all of the statements are true.
5.
Which of the following are classified as electromagnetic
radiation?
Correct Answer
D. All of the above
Explanation
Microwaves, UV rays, X-rays, and gamma rays are all classified as electromagnetic radiation. Electromagnetic radiation is a form of energy that consists of oscillating electric and magnetic fields and travels in waves. It includes a wide range of wavelengths, from long radio waves to short gamma rays. Microwaves are used for cooking and communication, UV rays are responsible for sunburns and tanning, and X-rays and gamma rays are used in medical imaging and radiation therapy. Therefore, all of the options listed in the answer are correct.
6.
UV radiation is antimicrobial because
Correct Answer
B. The energy present causes modifications or breaks in the DNA molecules.
Explanation
UV radiation is antimicrobial because the energy present in the radiation can cause modifications or breaks in the DNA molecules. This can disrupt the replication and functioning of the DNA, leading to cell death or inability to reproduce.
7.
The vegetative cells of Mycobacterium tuberculosis
are resistant to many germicides because of
Correct Answer
C. The waxy nature of the cell wall.
Explanation
The correct answer is the waxy nature of the cell wall. Mycobacterium tuberculosis has a unique cell wall composed of a waxy substance called mycolic acid. This waxy layer acts as a barrier, making the bacterium resistant to many germicides and antibiotics. The mycolic acid prevents the penetration of chemicals into the cell, making it difficult to kill the bacteria. This is one of the reasons why Mycobacterium tuberculosis is able to survive and persist in the human body, leading to the development of tuberculosis.
8.
Of all the known antibiotics that have been identified in
nature, __________ are clinically useful.
Correct Answer
A.
9.
Semisynthetic antibiotics
Correct Answer
A. Are natural antibiotics that have been chemically modified in the laboratory.
Explanation
Semisynthetic antibiotics are natural antibiotics that have been chemically modified in the laboratory. This means that they start as naturally occurring antibiotics but undergo chemical alterations to enhance their effectiveness or create new variations. These modifications can involve changing certain chemical groups or adding new ones to the original antibiotic molecule. The purpose of these modifications is to improve the antibiotic's properties, such as its spectrum of activity, stability, or resistance to degradation. By chemically modifying natural antibiotics, scientists can create semisynthetic antibiotics that are more potent, have fewer side effects, or can target specific types of bacteria.
10.
Antimicrobial drugs are often grouped according to
Correct Answer
D. All of the above
Explanation
Antimicrobial drugs are often grouped according to their molecular structure, spectrum of antimicrobial activity, and mechanism of action. This means that these drugs can be classified based on their chemical composition, the range of microorganisms they can target, and the specific way in which they work to inhibit or kill these microorganisms. Grouping antimicrobial drugs in this way allows for a better understanding of their characteristics and helps in choosing the most appropriate drug for a specific infection.
11.
Important targets of antibiotics in Bacteria are
Correct Answer
D. All of the above
Explanation
Antibiotics target various important components of bacteria, including the cell wall, the cytoplasmic membrane, and DNA replication and transcription elements. By disrupting these essential structures and processes, antibiotics can effectively inhibit bacterial growth and kill the bacteria. Therefore, the correct answer is "all of the above."
12.
The β-lactam antibiotics (like penicillin)
Correct Answer
B. Inhibit cell wall synthesis.
Explanation
β-lactam antibiotics, such as penicillin, work by inhibiting cell wall synthesis. The cell wall is an essential component of bacterial cells, providing structural support and protecting them from the external environment. By inhibiting cell wall synthesis, β-lactam antibiotics weaken the cell wall, making the bacteria more susceptible to damage and ultimately leading to their death. This mechanism of action is specific to β-lactam antibiotics and is one of the reasons why they are effective against a wide range of bacterial infections.
13.
Interferon is
Correct Answer
A. Host specific
Explanation
Interferon is a protein released by host cells in response to viral infection. It acts as a signaling molecule to alert neighboring cells of the presence of a virus and stimulate an antiviral response. Interferon is specific to the host because it is produced by the infected host cells and targets the same host cells and neighboring cells. It does not directly target the virus itself, making it host specific rather than virus specific.
14.
The use of a HEPA filter in a biological safety cabinet is
an application of filter sterilization using what type of filter?
Correct Answer
A. Depth filter
Explanation
A HEPA filter is a type of depth filter that is commonly used in biological safety cabinets. Depth filters work by trapping particles within the filter matrix as the air passes through it. This type of filter is effective in removing a wide range of contaminants, including bacteria, viruses, and other microorganisms. The use of a HEPA filter in a biological safety cabinet ensures that the air inside the cabinet is free from these contaminants, providing a safe environment for handling biological materials.
15.
Which of the following is a chemical agent that
is used to inhibit microbial growth inside the human body
Correct Answer
D. Chemotherapeutic agent
Explanation
A chemotherapeutic agent is a chemical agent that is used to inhibit microbial growth inside the human body. Unlike disinfectants and sanitizers, which are used on external surfaces, and antiseptics, which are used on living tissue, chemotherapeutic agents are specifically designed to target and kill or inhibit the growth of microorganisms within the body. These agents are commonly used in the treatment of various infections and diseases caused by bacteria, viruses, fungi, and parasites.
16.
Which is a unique macromolecule present in certain viruses that is a target for antiviral agents?
Correct Answer
C. Reverse transcriptase
Explanation
Reverse transcriptase is a unique macromolecule present in certain viruses that is a target for antiviral agents. It is an enzyme that converts the viral RNA genome into DNA, allowing the virus to integrate its genetic material into the host cell's DNA. By targeting reverse transcriptase, antiviral agents can inhibit this process and prevent viral replication. This makes reverse transcriptase an important target for the development of antiviral drugs, particularly for viruses such as HIV that use reverse transcription as part of their replication cycle.
17.
Which is not a reason why microorganisms may have an
inherent natural resistance to an antibiotic?
Correct Answer
D. The organism may be protected from the drug by its nuclear membrane
Explanation
The nuclear membrane is not a barrier that protects microorganisms from antibiotics. The nuclear membrane primarily functions to separate the nucleus from the cytoplasm and regulate the movement of molecules in and out of the nucleus. It does not play a role in protecting microorganisms from antibiotics.