1.
Which of the following glands is NOT part of the endocrine system?
Correct Answer
C. Salivary gland
Explanation
The endocrine system is a network of glands that produce and release hormones, which regulate various bodily functions. The pituitary, thyroid, and adrenal glands are all essential components of this system. The salivary glands, however, are part of the digestive system. They secrete saliva, which aids in the digestion of food, but they do not produce hormones that circulate throughout the body.
2.
After having a double-bacon cheeseburger with a milkshake, which of the following hormones would NOT be expected to increase?
Correct Answer
D. Glucagon
Explanation
After consuming a double-bacon cheeseburger with a milkshake, the body would typically experience an increase in various hormones to regulate digestion and metabolism. However, glucagon is not expected to increase in this scenario. Glucagon is a hormone that works in opposition to insulin, and its primary function is to increase blood glucose levels. Since the meal described in the question is high in carbohydrates and fats, the body would release insulin to facilitate glucose uptake and storage, but not glucagon. Therefore, glucagon would not be expected to increase in this situation.
3.
Which of the following hormones would bind to receptors located on the inside of a cell?
Correct Answer
A. Testosterone
Explanation
Testosterone is a steroid hormone that can easily pass through the cell membrane due to its lipid-soluble nature. Once inside the cell, testosterone binds to intracellular receptors, forming a hormone-receptor complex. This complex then enters the nucleus and binds to specific DNA sequences, influencing gene expression and protein synthesis. Therefore, testosterone binds to receptors located on the inside of the cell.
4.
Which of the following accurately describes thyroid hormone?
Correct Answer
D. Binds to receptors on the inside of the cell
Explanation
Thyroid hormone binds to receptors on the inside of the cell. This is because thyroid hormone is a lipid-soluble hormone that can easily cross the cell membrane. Once inside the cell, it binds to specific receptors located in the cytoplasm or nucleus. This binding activates the receptors, leading to changes in gene expression and ultimately affecting cellular metabolism and growth.
5.
Which of the following is a physiological function that is mediated by a hormone released by the posterior pituitary?
Correct Answer
C. Water retention
Explanation
Water retention is a physiological function that is mediated by a hormone released by the posterior pituitary. The hormone responsible for this function is called antidiuretic hormone (ADH) or vasopressin. ADH acts on the kidneys to increase water reabsorption, leading to water retention in the body. This helps in maintaining the body's water balance and preventing dehydration.
6.
Hormones travel through the blood stream and bind to receptors located on target cells. Which of the following would NOT bind to transmembrane proteins on the target cells?
Correct Answer
A. Estrogen
Explanation
Estrogen would NOT bind to transmembrane proteins on the target cells. Estrogen is a steroid hormone that can pass through the cell membrane and bind to intracellular receptors. Unlike other hormones, such as prolactin, insulin, and antidiuretic hormone, which bind to transmembrane receptors on the cell surface, estrogen has the ability to directly enter the target cells and interact with receptors in the cytoplasm or nucleus.
7.
Which of the following hormones would be expected to increase if you were studying all day for a test and skipped breakfast and lunch?
Correct Answer
A. Glucagon
Explanation
Glucagon is the correct answer because it is a hormone that is released by the pancreas in response to low blood sugar levels. When you skip meals, your body does not have enough glucose to use as energy, so it releases glucagon to stimulate the liver to break down stored glycogen into glucose, which can then be used by the body for energy. Therefore, studying all day for a test and skipping breakfast and lunch would cause a decrease in blood sugar levels, triggering the release of glucagon to help maintain adequate glucose levels in the body.
8.
Which hormone increases basal metabolic rate in the body?
Correct Answer
A. Thyroid Hormone
Explanation
The thyroid hormone is responsible for increasing the basal metabolic rate in the body. It regulates the body's metabolism by controlling the rate at which cells convert nutrients into energy. When the thyroid hormone levels are low, the metabolic rate decreases, leading to symptoms such as fatigue, weight gain, and slow heart rate. Conversely, when the thyroid hormone levels are high, the metabolic rate increases, resulting in symptoms such as weight loss, increased heart rate, and excessive sweating. Therefore, the correct answer is Thyroid Hormone.
9.
Growth factors and histamine are chemical agents released in small amounts that act locally on neighboring cells. Which of the following best describes the function of growth factors and histamine?
Correct Answer
C. Paracrine function
Explanation
Growth factors and histamine act locally on neighboring cells, indicating that their function is paracrine. Paracrine signaling involves the release of signaling molecules that act on nearby cells, rather than being transported through the bloodstream (endocrine) or acting on the same cell that released them (autocrine). Therefore, paracrine function best describes the function of growth factors and histamine.
10.
Which of the following is both an endocrine and exocrine gland?
Correct Answer
D. Pancreas
Explanation
The pancreas serves as both an endocrine and exocrine gland. It contains clusters of cells called the Islets of Langerhans, which secrete hormones like insulin and glucagon into the bloodstream, regulating blood sugar levels. This endocrine function is vital for maintaining glucose homeostasis. Simultaneously, the pancreas has exocrine functions, producing digestive enzymes that are released into the small intestine to aid in the digestion of food. The pancreatic enzymes play a crucial role in breaking down carbohydrates, proteins, and fats into absorbable nutrients during the digestive process. The pancreas are both an endocrine and exocrine gland because it produces and secretes bile, which is an exocrine function, and it also produces hormones such as insulin-like growth factor 1 (IGF-1) and angiotensinogen, which are endocrine functions.
11.
The primary role of the parathyroid gland is:
Correct Answer
B. To regulate serum calcium levels
Explanation
The parathyroid gland's primary role is to regulate serum calcium levels. This gland produces and releases parathyroid hormone (PTH), which helps to increase the concentration of calcium in the blood. PTH acts on the bones, kidneys, and intestines to increase calcium absorption, decrease calcium excretion, and release calcium from the bones when needed. This regulation of calcium levels is crucial for various physiological processes, including muscle and nerve function, blood clotting, and bone health.
12.
Antibodies directed against pancreatic cells result in these cells’ destruction. What laboratory abnormality might be seen in this scenario?
Correct Answer
B. Elevated serum glucose
Explanation
When antibodies attack pancreatic cells, it leads to their destruction. The pancreas is responsible for producing insulin, which helps regulate blood sugar levels. Therefore, the destruction of pancreatic cells would result in a decrease in insulin production and an increase in blood glucose levels. This explains why the laboratory abnormality seen in this scenario would be elevated serum glucose.
13.
Each hormone’s organ specificity is determined by:
Correct Answer
B. Its ability to interact with a specific receptor
Explanation
The organ specificity of each hormone is determined by its ability to interact with a specific receptor. This means that a hormone will only affect the organs or tissues that have the specific receptor for that hormone. The receptor acts as a target for the hormone, allowing it to bind and exert its effects on the target organ. Therefore, the ability of a hormone to interact with a specific receptor is crucial in determining its organ specificity.
14.
Hormones secreted by the hypothalamus would be classified as:
Correct Answer
C. Paracrine
Explanation
Hormones secreted by the hypothalamus would be classified as paracrine because paracrine hormones act locally on nearby cells without entering the bloodstream. The hypothalamus produces hormones that regulate various functions in the body, such as growth, metabolism, and reproduction. These hormones are released into the hypothalamic-pituitary portal system, which allows them to reach the pituitary gland and exert their effects on other endocrine glands. Therefore, the hormones secreted by the hypothalamus act locally on the pituitary gland rather than being distributed throughout the body via the bloodstream, making them paracrine in nature.
15.
All of the following are true of posterior pituitary hormones EXCEPT:
Correct Answer
A. They include direct and tropic hormones
Explanation
Posterior pituitary hormones do not include direct and tropic hormones. Direct hormones act directly on target tissues, while tropic hormones act on other endocrine glands to stimulate the release of other hormones. The posterior pituitary hormones, such as antidiuretic hormone (ADH) and oxytocin, are released from the posterior pituitary gland in response to nerve signals from the hypothalamus. Therefore, the statement "They include direct and tropic hormones" is not true for posterior pituitary hormones.
16.
The concentration of hormones in the bloodstream is regulated by:
Correct Answer
D. Positive and negative feedback loops
Explanation
Positive and negative feedback loops regulate the concentration of hormones in the bloodstream. Positive feedback loops amplify the production and release of hormones when certain conditions are met, while negative feedback loops reduce hormone production when levels are too high. These feedback mechanisms ensure that hormone levels are maintained within a narrow range, allowing for proper physiological functioning. Receptor antagonists, indirect growth-promoting effects, and nutritional signals to the endocrine gland may play a role in hormone regulation but are not the primary mechanisms involved.
17.
Unlike polypeptide hormones, steroid hormones:
Correct Answer
B. Are more likely to have an associated receptor in the cytosol or nucleus
Explanation
Steroid hormones are more likely to have an associated receptor in the cytosol or nucleus because they are lipid-soluble and can easily cross the cell membrane. Once inside the cell, they bind to specific receptors in the cytosol or nucleus, forming a hormone-receptor complex. This complex then acts as a transcription factor, directly binding to DNA and regulating gene expression. This mechanism allows steroid hormones to have a slower onset of action but longer-lasting effects compared to polypeptide hormones, which typically act through specific second messengers and have a more rapid onset of effect.
18.
The role of adenylate cyclase is:
Correct Answer
D. To cyclize ATP in order to generate second messengers
Explanation
Adenylate cyclase plays a crucial role in generating second messengers by cyclizing ATP. Second messengers are small molecules that act as intracellular signaling molecules, relaying signals from the cell surface to the interior. Adenylate cyclase catalyzes the conversion of ATP to cyclic AMP (cAMP), which is a common second messenger involved in various cellular processes. By cyclizing ATP, adenylate cyclase helps in amplifying the signal and transmitting it further downstream in the signaling pathway.
19.
Biosynthesis of steroids begins with:
Correct Answer
B. Binding of pyropHospHate to a terpene
Explanation
The correct answer is the binding of pyrophosphate to a terpene. This is because biosynthesis of steroids starts with the binding of pyrophosphate, a molecule containing two phosphate groups, to a terpene molecule. This reaction forms an isoprenoid intermediate, which is then further modified to generate sterols, the precursor molecules for steroid synthesis. Methylation of a sesquiterpene, generation of a sterol, and binding of two terpene groups are not the initial steps in the biosynthesis of steroids.
20.
Steroid hormones include which of the following:
Correct Answer
D. Sex hormones and adrenal cortical hormones
Explanation
Steroid hormones are a specific type of hormone that are derived from cholesterol and have a similar chemical structure. They are produced by various glands in the body, including the adrenal cortex and the gonads. Sex hormones, such as estrogen and testosterone, are examples of steroid hormones that are involved in the development and regulation of sexual characteristics and reproductive function. Adrenal cortical hormones, such as cortisol and aldosterone, are also steroid hormones produced by the adrenal cortex and are involved in various physiological processes, including metabolism, stress response, and electrolyte balance. Therefore, the correct answer is "Sex hormones and adrenal cortical hormones."