Dr Gawad Physiology Course Online Exam - Excitable - Lecture 1 (Introduction, Resting Membrane Potential)

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Quizzes Created: 2 | Total Attempts: 745

Questions: 7 | Attempts: 454 | Updated: Mar 21, 2023

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7 MCQs (Only one correct answer)Each MCQ: 1 mark, Total mark: 7 Allowed time: 8 minGood Luck

Questions and Answers

1.

According to the active (Na-K) pump:
- A.
  
  A trans membrane protein showing large number of binding sites on its interior aspect
- B.
  
  Inner ATPase activity is concerned to produce conformational change followed by 2 K+ pumped inside
- C.
  
  Ions migrate uphill against both (concentration + electrical) gradient
- D.
  
  Binding of (Na – K) to their respective binding sites is followed by activation of the inner ATPase
- E.
  
  All is true
Correct Answer
E. All is true

Explanation
The given statement suggests that all the statements mentioned are true. According to the active (Na-K) pump, there is a transmembrane protein with a large number of binding sites on its interior aspect. The inner ATPase activity is responsible for producing a conformational change, which leads to the pumping of 2 K+ ions inside. The ions migrate uphill against both the concentration and electrical gradient. The binding of (Na-K) to their respective binding sites activates the inner ATPase. Therefore, all the statements mentioned in the question are true.

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2
0
2.

The main responsible ion for the negative RMP is
- A.
  
  Na
- B.
  
  K
- C.
  
  Cl
- D.
  
  HCO3
Correct Answer
B. K

Explanation
The correct answer is K (potassium). Potassium ions play a crucial role in establishing the negative resting membrane potential (RMP) in cells. Inside the cell, there is a higher concentration of potassium ions compared to the outside. This concentration gradient creates an electrochemical potential difference, leading to the negative RMP. The movement of potassium ions through specific channels helps maintain this negative charge, which is essential for various cellular processes, including nerve conduction and muscle contraction.

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3.

The main cause of negative RMP is
- A.
  
  K outflux
- B.
  
  Na inflow
- C.
  
  Membrane imperbeability to protien
- D.
  
  None of the above
Correct Answer
C. Membrane imperbeability to protien

Explanation
The correct answer is "membrane impermeability to protein". The resting membrane potential (RMP) is the electrical potential difference across the cell membrane when the cell is at rest. It is mainly maintained by the movement of ions across the membrane. In this case, the impermeability of the membrane to protein means that proteins cannot freely move across the membrane, which can disrupt the balance of ions and result in a negative RMP. The other options, K outflux and Na inflow, can contribute to changes in the RMP but are not the main cause of a negative RMP.

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4.

RMP is due to which of the following:
- A.
  
  Passive movements of ions along the membrane
- B.
  
  Selective permeability of the membrane
- C.
  
  Active Na and K transport
- D.
  
  Impermeability of the membrane to protein
- E.
  
  All of the above
Correct Answer
E. All of the above

Explanation
The resting membrane potential (RMP) is due to a combination of factors. Passive movements of ions along the membrane contribute to the establishment of the RMP. The selective permeability of the membrane allows certain ions to pass through more easily than others, further influencing the RMP. Active transport of sodium (Na) and potassium (K) ions across the membrane also plays a role in establishing and maintaining the RMP. Additionally, the impermeability of the membrane to proteins contributes to the RMP. Therefore, all of these factors together contribute to the resting membrane potential.

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5.

Isopotential means
- A.
  
  More negative
- B.
  
  More positive
- C.
  
  Same potential
- D.
  
  None of the above.
Correct Answer
C. Same potential

Explanation
Isopotential refers to having the same potential. In this context, it means that all points or regions being referred to have the same electrical potential. This means that there is no difference in the electrical potential between these points or regions, indicating a state of equilibrium or balance in terms of electrical charge.

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6.

The main cause of RMP is
- A.
  
  Unequal distribution of ions
- B.
  
  That it is totally dependant on a passive process
- C.
  
  That it is totally dependant on active process
- D.
  
  The osmotic power of Na
Correct Answer
A. Unequal distribution of ions

Explanation
The main cause of RMP, or resting membrane potential, is the unequal distribution of ions. This refers to the difference in concentration and distribution of ions, such as sodium (Na+), potassium (K+), and chloride (Cl-), inside and outside the cell. This unequal distribution creates an electrical charge across the cell membrane, resulting in a potential difference. This potential difference is essential for various cellular processes and the transmission of nerve impulses.

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7.

Regarding K transportation during RMP
- A.
  
  It is slower than Na
- B.
  
  It is limited by the positivity of the outer membrane
- C.
  
  It is from outer to inner surface by active process
- D.
  
  It is as the same amount of Cl movement
Correct Answer
B. It is limited by the positivity of the outer membrane

Explanation
The correct answer suggests that the transportation of K during RMP is limited by the positivity of the outer membrane. This implies that the movement of K ions is influenced by the positive charge on the outer membrane, which acts as a barrier or restriction for the transport process. This limitation could potentially affect the overall speed or efficiency of K transportation during RMP.

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Mar 21, 2023

Quiz Edited by
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Feb 16, 2017

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Drgoakjsdhh

Dr Gawad Physiology Course Online Exam - Excitable - Lecture 1 (Introduction, Resting Membrane Potential)

According to the active (Na-K) pump:

The main responsible ion for the negative RMP is

The main cause of negative RMP is

RMP is due to which of the following:

Isopotential means

The main cause of RMP is

Regarding K transportation during RMP