NCLEX Pharmacology Quiz 31 Anti-infective Drugs And Topical Agents
All questions are shown, but the results will only be given after you’ve finished the quiz. You are given 1 minute per question, a total of 10 minutes in this quiz.
- 1.
Antitubercular therapy may be determined ineffective when:
- A.
Sputums are negative.
- B.
Symptoms resolve.
- C.
Hepatitis results.
- D.
Drug-resistant bacteria emerge.
Correct Answer
D. Drug-resistant bacteria emerge.Explanation
The emergence of drug-resistant bacteria indicates that antitubercular therapy is ineffective because the drug(s) are no longer ending bacterial multiplication.Rate this question:
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- 2.
Fluconazole (Diflucan) can be administered to a client with:
- A.
Pneumococcal meningitis
- B.
Oral thrush
- C.
Cryptococcal meningitis
- D.
Pneumococcal pneumonia
Correct Answer
C. Cryptococcal meningitisExplanation
Fluconazole (Diflucan) is a drug given for the treatment of cryptococcal meningitis. A and D are incorrect because pneumococcal meningitis and pneumonia are not caused by fungal infections. Oral thrush is treated with a more mild antifungal. such as nystatin.Rate this question:
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- 3.
When administering amphotericin B. which of the following must be used?
- A.
A brown bag to protect the infusion from the light
- B.
A diluent of 5% dextrose with no preservatives
- C.
A diluent of normal saline with alcohol
- D.
A micron filter of above l ?
Correct Answer
B. A diluent of 5% dextrose with no preservativesExplanation
Amphotericin B must be mixed with a solution with no preservatives. The solution is sensitive to light but does not require the infusion to be covered. A micron filter should not be used; if unavoidable. it must be less than 1 ?.Rate this question:
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- 4.
Which of the following nursing diagnoses might occur when administering large parenteral doses of amphotericin B with vancomycin (Vancocin)?
- A.
Decreased cardiac output
- B.
Ineffective airway clearance
- C.
Ineffective breathing pattern
- D.
Fluid volume excess
Correct Answer
D. Fluid volume excessExplanation
These two drugs are both nephrotoxic. so this nursing diagnosis may result from renal problems.Rate this question:
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- 5.
Arvic. a 16-year-old student. has acquired systemic fungal infection. he should be treated with:
- A.
Amphotericin B
- B.
Miconazole (Monistat IV)
- C.
Ketoconazole
- D.
Griseofulvin (Fulvicin)
Correct Answer
A. AmpHotericin BExplanation
Serious life-threatening fungal infections are treated with amphotericin B.Rate this question:
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- 6.
Which of the following must always be present before beginning antifungal therapy?
- A.
Coagulation profile
- B.
Confirmed diagnosis
- C.
Biopsy of infected site
- D.
Urinalysis
Correct Answer
B. Confirmed diagnosisExplanation
The diagnosis of fungal infection as opposed to infection caused by virus or bacteria is necessary before beginning therapy with antifungal agents.Rate this question:
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- 7.
Which choice describes the action of nucleoside analogs?
- A.
Exert anti-HIV activity at the reverse transcriptase level and cause premature termination of viral DNA chain synthesis
- B.
Completely stop the replication of HIV virus
- C.
Allow for a patient to become non-contagious after taking for at least 3 days
- D.
Are all equally effective and free of side effects
Correct Answer
A. Exert anti-HIV activity at the reverse transcriptase level and cause premature termination of viral DNA chain synthesisExplanation
This choice correctly describes the action of nucleoside analogs.Rate this question:
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- 8.
Which of the following true about protease inhibitors?
- A.
Work better when used alone.
- B.
Are the same as nucleoside analogs.
- C.
Affect replication of HIV at different stage than nucleoside analogs.
- D.
Have a high level of toxicity.
Correct Answer
C. Affect replication of HIV at different stage than nucleoside analogs.Explanation
Protease inhibitors cleave the viral polyprotein precursors that are essential for the maturation of infectious virus. Nucleosides interfere with replication of HIV by inhibiting reverse transcriptase. Protease inhibitors work best when used in combination with other drugs.Rate this question:
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- 9.
The human cells specifically affected by HIV are:
- A.
Gonadocytes
- B.
CD4+ T lymphocytes
- C.
Islet cells
- D.
Red blood cells
Correct Answer
B. CD4+ T lympHocytesExplanation
HIV directly affects CD4+ T lymphocytes.Rate this question:
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- 10.
Which of the following statements is TRUE about monotherapy for treatment of HIV disease?
- A.
It is the only FDA-approved treatment for HIV disease
- B.
It is able to effectively destroy all viral particles of HIV
- C.
It interferes with the replication of HIV virus without causing any side effects
- D.
It appears to cause rapid resistance.
Correct Answer
D. It appears to cause rapid resistance.Explanation
With monotherapy, resistance can emerge within a few months.Rate this question:
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Sep 21, 2023Quiz Edited by
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Aug 13, 2017Quiz Created by
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