Blood Bank : Blood Product & Blood Group Systems Quiz: Exam!
(194).jpg "Blood Bank : Blood Product & Blood Group Systems Quiz: Exam! - Quiz")
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- 1.
The minimum hemoglobin concentration in a fingerstick from a male blood donor is:
- A.
12.0 g/dL (120 g/L)
- B.
12.5 g/dL (125 g/L)
- C.
13.5 g/dL (135 g/L)
- D.
15.0 g/dL (150 g/L)
Correct Answer
B. 12.5 g/dL (125 g/L)Explanation
All donors, regardless of sex, require
a minimum hemoglobin of 12.5 g/dL
(125 g/L). The value must not be performed
on an earlobe stick.Rate this question:
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- 2.
A cause for permanent deferral of blood donation is:
- A.
Diabetes
- B.
Residence in an endemic malaria region
- C.
History of jaundice of uncertain cause
- D.
History of therapeutic rabies vaccine
Correct Answer
C. History of jaundice of uncertain causeExplanation
Jaundice is a sign of liver impairment,
which might be due to HBV or HCV.
Infection with HBV and HCV is a cause for
indefinite deferral.Rate this question:
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- 3.
Which of the following prospective donors would be accepted for donation?
- A.
32-year-old woman who received a transfusion in a complicated delivery 5 months previously
- B.
19-year-old sailor who has been stateside for 9 months and stopped taking his anti-malarial medication 9 months previously
- C.
22-year-old college student who has a temperature of 99.2°F (37.3°C) and states that he feels well, but is nervous about donating
- D.
45-year-old woman who has just recovered from a bladder infection and is still taking antibiotics
Correct Answer
C. 22-year-old college student who has a temperature of 99.2°F (37.3°C) and states that he feels well, but is nervous about donatingExplanation
The receipt of blood products is a 6-month deferral, the deferral for travel to areas endemic for malaria is 12 months regardless of antimalarial prophylaxis,
and a person taking antibiotics may have bacteremia. The requirement for
temperature is not over 37.5°C or 99.5°F.Rate this question:
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- 4.
Which one of the following constitutes permanent rejection status of a donor?
- A.
A tattoo 5 months previously
- B.
Recent close contact with a patient with viral hepatitis
- C.
2 units of blood transfused 4 months previously
- D.
Confirmed positive test for HBsAg 10 years previously
Correct Answer
D. Confirmed positive test for HBsAg 10 years previouslyExplanation
A positive test for HbsAg at any time is an indefinite deferral.Rate this question:
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- 5.
According to AABB standards, which of the following donors may be accepted as a blood donor?
- A.
Traveled to an area endemic for malaria 9 months previously
- B.
Spontaneous abortion at 2 months of pregnancy, 3 months previously
- C.
Resides with a known hepatitis patient
- D.
Received a blood transfusion 22 weeks previously
Correct Answer
B. Spontaneous abortion at 2 months of pregnancy, 3 months previouslyExplanation
A woman who had a spontaneous abortion at 2 months of pregnancy, 3 months previously would be acceptable. A donor is acceptable if she has not been pregnant in the previous 6 weeks.Rate this question:
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- 6.
Below are the results of the history obtained from a prospective female blood donor: age: 16 temperature: 99.0°F (37.2°C) Hct: 36% history: tetanus toxoid immunization 1 week previously How many of the above results excludes this donor from giving blood for a routine transfusion?
- A.
None
- B.
1
- C.
2
- D.
3
Correct Answer
B. 1Explanation
The Hct must be > 38%. A donor may be 16 unless state law differs. Temperature must not exceed 99.5°F/37.5°C, blood pressure must be less than 180 mm Hg systolic and less than 100 mm Hg diastolic, pulse 50-100 unless an athlete (which can be lower). Toxoids and vaccines from synthetic or killed sources have no deferral.Rate this question:
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- 7.
For apheresis donors who donate platelets more frequently than every 4 weeks, a platelet count must be performed prior to the procedure and be at least:
- A.
150 x 103/μL (150 x 109/L)
- B.
200 x 103/ μL (200 x 109/L)
- C.
250 x 103/μL (250 x 109/L)
- D.
300 x 103/ μL (300 x 109/L)
Correct Answer
A. 150 x 103/μL (150 x 109/L)Explanation
The minimum platelet count required for frequent repeat donors is 150 x 103/μL (150 x 109/L). A platelet count is not required prior to the first donation or if the interval between donations is at least 4 weeks.Rate this question:
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- 8.
Prior to blood donation, the intended venipuncture site must be cleaned with a scrubsolution containing:
- A.
Hypochlorite
- B.
Isopropyl alcohol
- C.
10% aceton
- D.
PVP iodine complex
Correct Answer
D. PVP iodine complexExplanation
The scrub must use iodine, eg, PVP iodine complex. Donors who are sensitive to iodine can have the area cleaned with a preparation of 2% chlorhexidine and 70% isopropyl alcohol.Rate this question:
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- 9.
All donor blood testing must include:
- A.
Complete Rh phenotyping
- B.
Anti-CMV testing
- C.
Direct antiglobulin test
- D.
Serological test for syphilis
Correct Answer
D. Serological test for sypHilisExplanation
Testing for syphilis was the first mandated donor screening test for infectious disease and is still part of donor screening.Rate this question:
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- 10.
During the preparation of Platelet Concentrates from Whole Blood, the blood should be:
- A.
Cooled towards 6'C
- B.
Cooled towards 20°-24°C
- C.
Warmed to 37°C
- D.
Heated to 57°C
Correct Answer
B. Cooled towards 20°-24°CExplanation
Platelets are prepared and stored at 20° -24°C for optimum function.Rate this question:
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- 11.
The most common cause of posttransfusion hepatitis can be detected in donors by testing for:
- A.
Anti-HCV
- B.
HBsAg
- C.
Anti-HAV IgM
- D.
Anti-HBe
Correct Answer
B. HBsAgExplanation
The most common posttransfusion hepatitis is hepatitis B. The estimated risk of transmission is 1:220,000 units transfused. The risk of hepatitis C transmission is 1:1,800,000 units. Hepatitis B surface
antigen (HBsAg) is a required donor test for
detection of acute or chronic HBV infection.Rate this question:
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- 12.
The Western blot is a confirmatory test for the presence of:
- A.
CMV antibody
- B.
Anti-HIV-1
- C.
HBsAg
- D.
Serum protein abnormalities
Correct Answer
B. Anti-HIV-1Explanation
Western blot uses purified HIV proteins to confirm reactilrity in samples whose screening test for anti-HIV is positive.Rate this question:
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- 13.
The test that is currently used to detect donors who are infected with the AIDS virus is:
- A.
Anti-HBc
- B.
Anti-HIV 1,2
- C.
HBsAg
- D.
ALT
Correct Answer
B. Anti-HIV 1,2Explanation
The causative agent for AIDS is the human immunodeficiency virus types 1
and 2.Rate this question:
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- 14.
A commonly used screening method for anti-HIV-1 detection is:
- A.
Latex agglutination
- B.
Radioimmunoassay (RIA)
- C.
Thin-layer-chromatography (TLC)
- D.
Enzyme-labeled immunosorbent assay (ELISA)
Correct Answer
D. Enzyme-labeled immunosorbent assay (ELISA)Explanation
The enzyme-labeled immunosorbent assay (ELISA) method is a very sensitive method employed to screen donors for markers of transfusion-transmitted viruses.Rate this question:
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- 15.
Rejuvenation of a unit of Red Blood Cells is a method used to:
- A.
Remove antibody attached to RBCs
- B.
Remove antibody attached to RBCs
- C.
Restore 2,3-DPG and ATP to normal levels
- D.
Filter blood clots and other debris
Correct Answer
C. Restore 2,3-DPG and ATP to normal levelsExplanation
Rejuvenation of RBCs uses additives to restore or enhance 2,3-DPG and ATP levels.Rate this question:
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- 16.
Unit of packed cells is split into 2 aliquots under closed sterile conditions at 8 AM. The expiration timeline for each aliquot is now:
- A.
4 PM on the same day
- B.
8 PM on the same day
- C.
8 AM the next morning
- D.
The original date of the unsplit unit
Correct Answer
D. The original date of the unsplit unitExplanation
Sterile docking devices allow entry into donor units without affecting the expiration date of the product.Rate this question:
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- 17.
A unit of Red Blood Cells expiring in 35 days is split into 5 small aliquots using a sterile pediatric quad set and a sterile connecting device. Each aliquot must be labeled as expiring in:
- A.
6 hours
- B.
12 hours
- C.
5 days
- D.
35 days
Correct Answer
D. 35 daysExplanation
Sterile docking devices allow entry into donor units without affecting the expiration date of the product.Rate this question:
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- 18.
When platelets are stored on a rotator set on an open bench top, the ambient air temperature must be recorded:
- A.
Once a day
- B.
Twice a day
- C.
Every 4 hours
- D.
Every hour
Correct Answer
C. Every 4 hoursExplanation
If storage devices do not have automated temperature recording,
temperature must be manually monitored every 4 hours.Rate this question:
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- 19.
Which of the following is the correct storage temperature for the component ?
- A.
Cryoprecipitated AHF, 4°C
- B.
Fresh Frozen Plasma (FFP), -20°C
- C.
Red Blood Cells, Frozen, - 40°C
- D.
Platelets, 37°C
Correct Answer
B. Fresh Frozen Plasma (FFP), -20°CExplanation
Fresh Frozen Plasma is stored at -l8°C or below for 12 months.Rate this question:
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- 20.
A unit of Red Blood Cells is issued at 9:00 AM. At 9:10 AM the unit is returned to the Blood Bank. The container has not been entered, but the unit has not been refrigerated during this time span. The best course of action for the technologist is to:
- A.
Culture the unit for bacterial contamination
- B.
Discard the unit if not used within 24 hours
- C.
Store the unit at room temperature
- D.
Record the return and place the unit back into inventory
Correct Answer
D. Record the return and place the unit back into inventoryExplanation
Blood may be returned to the blood bank after issue provided that 1) the container has not been entered, 2) at least 1 sealed segment is attached to the container, 3) visual inspection of the unit is satisfactory and documented, and 4) the unit has been maintained at the appropriate storage or transport temperature. Studies have shown that refrigerated components
retain an acceptable temperature of< l0°C
for up to 30 minutes after removal from
the refrigerator.Rate this question:
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- 21.
The optimum storage temperature for Red Blood Cells, Frozen is:
- A.
-80°C
- B.
-20°C
- C.
- 12°C
- D.
4°C
Correct Answer
A. -80°CExplanation
Red Blood Cells, Frozen with 40% glycerol are stored at -65°C or lower.Rate this question:
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- 22.
The optimum storage temperature for Red Blood Cells is:
- A.
-80°C
- B.
20°C
- C.
-12°C
- D.
4°C
Correct Answer
D. 4°CExplanation
Red Blood Cells are stored at 1 ° -6°C.Rate this question:
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- 23.
If the seal is entered on a unit of Red Blood Cells stored at 1 °C to 6°C, what is the maximum allowable storage period, in hours?
- A.
6
- B.
24
- C.
48
- D.
72
Correct Answer
B. 24Explanation
If the seal is broken during processing, components are considered to be prepared in an open system, rather than a closed system. The expiration time for Red Blood Cells in an open system is 24 hours.Rate this question:
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- 24.
The optimum storage temperature for cryoprecipitated AHF is:
- A.
-20°C
- B.
-12°C
- C.
4°C
- D.
22°C
Correct Answer
A. -20°CExplanation
Cryoprecipitated AHF is stored at-l8°C or lowerRate this question:
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- 25.
Cryoprecipitated AHF must be transfused within what period of time following thawing and pooling?
- A.
4 hours
- B.
8 hours
- C.
12 hours
- D.
24 hours
Correct Answer
A. 4 hoursExplanation
Cryoprecipitate must be transfused within 4 hours of pooling.Rate this question:
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- 26.
Platelets prepared in a polyolefin type container, stored at 22° -24°C in 50 mL of plasma, and gently agitated can be used for up to:
- A.
24 hours
- B.
48 hours
- C.
3 days
- D.
5 days
Correct Answer
D. 5 daysExplanation
Whole Blood-derived platelets are stored at 20' -24 °C with continuous gentle agitation. Platelets prepared by the PRP method may be stored for up to 5 days.Rate this question:
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- 27.
The optimum storage temperature for platelets is:
- A.
- 20°C
- B.
- 12°C
- C.
4°C
- D.
22°C
Correct Answer
D. 22°CExplanation
The required temperature for storage of platelets is 20' -24°C.Rate this question:
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- 28.
According to AABB standards, Fresh Frozen Plasma must be infused within what period of time following thawing?
- A.
24 hours
- B.
36 hours
- C.
48 hours
- D.
72 hours
Correct Answer
A. 24 hoursExplanation
Per AABB standards, thawed FFP should be stored at 1 ° -6°C for no more than
24 hours.Rate this question:
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- 29.
Cryoprecipitated AHF, if maintained in the frozen state at -18'C or below, has a shelf life of:
- A.
42 days
- B.
6 months
- C.
12 months
- D.
36 months
Correct Answer
C. 12 monthsExplanation
Cryoprecipitate has a shelf life of 12 months in the frozen state.Rate this question:
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- 30.
Once thawed, Fresh Frozen Plasma must be transfused within:
- A.
4 hours
- B.
8 hours
- C.
12 hours
- D.
24 hours
Correct Answer
D. 24 hoursExplanation
Once thawed, FFP is stored at 1 ° -6°C for up to 24 hours.Rate this question:
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- 31.
An important determinant of platelet viability following storage is:
- A.
Plasma potassium concentration
- B.
Plasma pH
- C.
Prothrombin time
- D.
Activated partial thromboplastin time
Correct Answer
B. Plasma pHExplanation
The pH of platelets should be maintained at 6.2 or above throughout the storage period.Rate this question:
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- 32.
In the liquid state, plasma must be stored at:
- A.
1°- 6°C
- B.
22°c
- C.
37°C
- D.
56°c
Correct Answer
A. 1°- 6°CExplanation
The required temperature for storage of thawed plasma is 1°- 6°C.Rate this question:
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- 33.
During storage, the concentration of 2,3-diphosphoglycerate (2,3-DPG) decreases in a unit of:
- A.
Platelets
- B.
Fresh Frozen Plasma
- C.
Red Blood Cells
- D.
Cryoprecipitated AHF
Correct Answer
C. Red Blood CellsExplanation
2,3-DPG declines during storage of Red Blood Cells, causing a "shift-to-the-left" in the oxygen dissociation curve and an impaired ability to deliver oxygen to the tissues.Rate this question:
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- 34.
Cryoprecipitated AHF:
- A.
Is indicated for fibrinogen deficiencies
- B.
Should be stored at 4 °C prior to administration
- C.
Will not transmit hepatitis B virus
- D.
Is indicated for the treatment of hemophilia B
Correct Answer
A. Is indicated for fibrinogen deficienciesExplanation
Cryoprecipitate is used primarily for fibrinogen replacement. It is stored at room temperature (20° -24 °C) after thawing and must be infused within 6 hours. If pooled with other cryo units, it must be infused within 4 hours.Rate this question:
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- 35.
Which apheresis platelets product should be irradiated?
- A.
Autologous unit collected prior to surgery
- B.
Random stock unit going to a patient with DIC
- C.
A directed donation given by a mother for her son
- D.
A directed donation given by an unrelated family friend
Correct Answer
C. A directed donation given by a mother for her sonExplanation
Blood products from blood relatives containing viable lymphocytes must be irradiated to inhibit the proliferation of T cells and subsequent GVHD.Rate this question:
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- 36.
Irradiation of a unit of Red Blood Cells is done to prevent the replication of donor:
- A.
Granulocytes
- B.
Lymphocytes
- C.
Red cells
- D.
Platelets
Correct Answer
B. LympHocytesExplanation
Irradiation inhibits proliferation of T lymphocytes.Rate this question:
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- 37.
Plastic bag overwraps are recommended when thawing units of FFP in 37°C water baths because they prevent:
- A.
The FFP bag from cracking when it contacts the warm water
- B.
Water from slowly dialyzing across the bag membrane
- C.
The entry ports from becoming contaminated with water
- D.
The label from peeling off as the water circulates in the bath
Correct Answer
C. The entry ports from becoming contaminated with waterExplanation
FFP thawed in a water bath should be protected so that entry ports are not contaminated with water. One can may use a plastic overwrap or keep ports above the water level.Rate this question:
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- 38.
Which of the following blood components must be prepared within 8 hours after phlebotomy?
- A.
Red Blood Cells
- B.
Fresh Frozen Plasma
- C.
Red Blood Cells, Frozen
- D.
Cryoprecipitated AHF
Correct Answer
B. Fresh Frozen PlasmaExplanation
Fresh Frozen Plasma (FFP) must be separated and frozen within 8 hours of Whole Blood collection.Rate this question:
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- 39.
Cryoprecipitated AHF contains how many units of Factor VIII?
- A.
40
- B.
80
- C.
130
- D.
250
Correct Answer
B. 80Explanation
Cryoprecipitate contains at least 80 units of AHF.Rate this question:
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- 40.
Which of the following blood components contains the most Factor VIII concentration relative to volume?
- A.
Single-Donor Plasma
- B.
Cryoprecipitated AHF
- C.
Fresh Frozen Plasma
- D.
Platelets
Correct Answer
B. Cryoprecipitated AHFExplanation
Cryoprecipitated AHF contains at least 80 IU of Factor VIII concentrated in about 10 mL of plasma.Rate this question:
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- 41.
The most effective component to treat a patient with fibrinogen deficiency is:
- A.
Fresh Frozen Plasma
- B.
Platelets
- C.
Fresh Whole Blood
- D.
Cryoprecipitated AHF
Correct Answer
D. Cryoprecipitated AHFExplanation
Cryoprecipitate is indicated as a source of fibrinogen for hypofibrinogenemia. It contains a minimum of 150 mg of fi.brinogen concentrated in a small volume of plasma .Rate this question:
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- 42.
A blood component prepared by thawing Fresh Frozen Plasma at refrigerator temperature and removing the fluid portion is:
- A.
Plasma Protein Fraction
- B.
Cryoprecipitated AHF
- C.
Factor IX Complex
- D.
FP24
Correct Answer
B. Cryoprecipitated AHFExplanation
Cryoprecipitate is the fraction of plasma proteins that precipitate when FFP is slowly thawed at1°- 6°C.Rate this question:
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- 43.
Upon inspection, a unit of platelets is noted to have visible clots, but otherwise appears normal. The technologist should:
- A.
Issue without concern
- B.
Filter to remove the clots
- C.
Centrifuge to express off the clots
- D.
Quarantine for Gram stain and culture
Correct Answer
D. Quarantine for Gram stain and cultureExplanation
Clots in the unit may indicate contaminationRate this question:
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- 44.
According to AABB Standards, at least 90% of all Apheresis Platelets units tested shall contain a minimum of how many platelets?
- A.
5.5 X 1010
- B.
6.5 X 1010
- C.
3.0. X 1011
- D.
5.0 X 1011
Correct Answer
C. 3.0. X 1011Explanation
Per AABB standards, at least 90% of platelet pheresis units sampled must contain at least 3.0 x 1011 platelets.Rate this question:
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- 45.
According to AABB Standards, Platelets prepared from Whole Blood shall have at least:
- A.
5.5 x 1010 platelets per unit in at least 90% of the units tested
- B.
6.5 x 1110 platelets per unit in 90% of the units tested
- C.
7.5 x 1010 platelets per unit in 100% of the units tested
- D.
8.5 x 1010 platelets per unit in 95% of the units tested
Correct Answer
A. 5.5 x 1010 platelets per unit in at least 90% of the units testedExplanation
Per AABB standards, at least 90% of the platelet units prepared from Whole Blood that are sampled must contain at least
5.5 x 1010 platelets.Rate this question:
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- 46.
Which of the following is proper procedure for preparation of Platelets from Whole Blood?
- A.
Light spin followed by a hard spin
- B.
Light spin followed by 2 hard spins
- C.
2 light spins
- D.
Hard spin followed by a light spin
Correct Answer
A. Light spin followed by a hard spinExplanation
Whole blood-derived Platelets are prepared by a light spin to separate the Red Blood Cells from the platelet-rich plasma (PRP), followed by a heavy spin of the PRP to concentrate the platelets.Rate this question:
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- 47.
According to AABB standards, what is the minimum pH required for Platelets at the end of the storage period?
- A.
6.0
- B.
6.2
- C.
6.8
- D.
7.0
Correct Answer
B. 6.2Explanation
Per AABB standards, at least 90% of platelet units sampled must have a pH of at least 6.2 at the end of the allowable storage.Rate this question:
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- 48.
According to AABB standards, Platelets must be:
- A.
Gently agitated if stored at room temperature
- B.
Separated within 12 hours of Whole Blood collection
- C.
Suspended in sufficient plasma to maintain a pH of 5.0 or lower
- D.
Prepared only from Whole Blood units that have been stored at 4°C for 6 hours
Correct Answer
A. Gently agitated if stored at room temperatureExplanation
Per AABB standards, store Platelets at 20°-24°C with continuous agitation. Platelets must be separated from Whole Blood units and maintained at a
temperature of at least 20°C. The pH must be at least 6.2 at the end of the storage time.Rate this question:
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- 49.
A unit of Whole Blood-derived (random donor) Platelets should contain at least:
- A.
1.0 x 1010 platelets
- B.
5.5 x 1010 platelets
- C.
5.5 x 1011 platelets
- D.
90% of the platelets from the original unit of Whole Blood
Correct Answer
B. 5.5 x 1010 plateletsExplanation
Whole blood-derived (random donor) Platelets should contain at least 5.5 x 1010 platelets platelets, be stored with continuous agitation at 20° -24°C, and have a pH of
6.2 or higher when tested at the end of the storage period.Rate this question:
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- 50.
Platelets prepared by apheresis should contain at least:
- A.
1 x 1010 platelets
- B.
3 x 1010 platelets
- C.
3 x 1011 platelets
- D.
5 x 1011 platelets
Correct Answer
C. 3 x 1011 plateletsExplanation
Apheresis (single donor) Platelets should contain at least 3.0 x 1011 platelets, be stored with continuous agitation at 20° -24°C, and have a pH of 6.2 or higher
when tested at the end of the storage period.Rate this question:
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Sep 04, 2024Quiz Edited by
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May 12, 2017Quiz Created by
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