1.
Wuchereria bancrofti and Brugia microfilariae have a diurnal periodicity.
Correct Answer
B. False
Explanation
They have a nocturnal periodicity from 10pm to 2 am.
2.
If an unsheathed microfilariae that is 250 - 300 microns long (big at x100) has nuclei that don't go to its tail tip it is:
Correct Answer
B. Onchocerca volvulus
Explanation
If an unsheathed microfilariae that is 250 - 300 microns long (big at x100) has nuclei that don't go to its tail tip, it is likely to be Onchocerca volvulus. This is because Onchocerca volvulus is known to have microfilariae with nuclei that do not extend to the tail tip. The other options, Mansonella Ozzardi, Brugia malayi, and Wuchereria bancrofti, do not exhibit this characteristic.
3.
The L1 larvae of W.bancrofti and B.malayi develop to L3 larvae in the...
Correct Answer
C. Thoracic muscles of the mosquito vector
Explanation
The L1 larvae of W.bancrofti and B.malayi develop to L3 larvae in the thoracic muscles of the mosquito vector. This is the location where the larvae undergo their final development before being transmitted back to humans through mosquito bites. The thoracic muscles provide a suitable environment for the larvae to mature and prepare for their next stage of development. Once the mosquitoes bite humans, the L3 larvae are injected into the bloodstream, where they can then migrate to the lymphatic system and cause lymphatic filariasis.
4.
Pulmonary tropical eosinophilia syndrome occurs in Loa loa infection.
Correct Answer
B. False
Explanation
It occurs in W.bancrofti and B.malayi infection. Symptoms are nocturnal cough, wheezing, and fever.
5.
Mass drug administration for lymphatic filariasis has to occur for how long and in what population percentage to achieve eradication.
Correct Answer
A. 4 - 6 years and 70% population coverage.
Explanation
Mass drug administration for lymphatic filariasis needs to occur for a period of 4-6 years and in a population coverage of 70% in order to achieve eradication. This duration allows for repeated treatment cycles to target the entire at-risk population and ensure that all infected individuals receive the necessary medication. The 70% population coverage is necessary to break the transmission cycle of the disease by reducing the number of infected individuals and preventing further spread.
6.
Wuchereria bancrofti is found...
Correct Answer
C. In Africa, Asia and South America
Explanation
Wuchereria bancrofti is a parasitic worm that causes lymphatic filariasis, a disease commonly known as elephantiasis. This disease is prevalent in tropical and subtropical regions of the world. The correct answer states that Wuchereria bancrofti is found in Africa, Asia, and South America, which accurately reflects the geographic distribution of this parasite.
7.
What drug is used to treat lymphatic filariasis caused by Wuchereria bancrofti in areas of Africa co-endemic for Onchocerciasis?
Correct Answer
C. Ivermectin
Explanation
All of these are used to treat LF, however, Ivermectin is used in areas co-endemic for onchocerciasis as it treats both. It was donated free for this by Merck.
8.
Treatment of Wolbachia with doxycycline causes sterilization of the female worms.
Correct Answer
A. True
Explanation
Treatment of Wolbachia with doxycycline causes sterilization of the female worms. This is because doxycycline is an antibiotic that effectively targets and kills the Wolbachia bacteria, which are essential for reproduction in female worms. By eliminating Wolbachia, the female worms become unable to reproduce, resulting in sterilization. Therefore, the statement is true.
9.
The vector for Onchocerciasis is:
Correct Answer
B. Blackfly
Explanation
The correct answer is Blackfly. Onchocerciasis, also known as river blindness, is caused by the parasitic worm Onchocerca volvulus. The blackfly, specifically of the Simulium genus, serves as the vector for this disease. The blackfly bites an infected individual and ingests the microfilariae (larvae) of the parasite. These microfilariae then develop within the blackfly and are transmitted to another individual when the blackfly bites again. Therefore, the blackfly plays a crucial role in the transmission of Onchocerciasis.
10.
These three forms of skin disease may occur in Onchocerciasis.
Correct Answer(s)
A. Leopard skin depigmentation
C. Sowda
D. Lizard skin atropHy
Explanation
Larval current occurs in Strongyloides infection. Sowda is an unusual form of Oncho that occurs in Yemen.
11.
The Mazotti test involves giving DEC to patients with Onchocerciasis.
Correct Answer
A. True
Explanation
This test causes pruritus in Onchocerciasis patients when given DEC.
12.
Onchocercoma nodules occur mainly...
Correct Answer
C. Over bony prominences
Explanation
Onchocercoma nodules occur mainly over bony prominences. These nodules are caused by the parasitic infection known as onchocerciasis, or river blindness. The adult worms of the parasite Onchocerca volvulus live in the subcutaneous tissues, and the nodules form as a result of the body's immune response to the presence of the worms. Bony prominences, such as the elbows, knees, and hips, provide a suitable environment for the development of these nodules.
13.
Mansonella ozzardi is found in the old world.
Correct Answer
B. False
Explanation
It is found in the New World.
14.
Mansonella microfilariae are unsheathed.
Correct Answer
A. True
Explanation
Mansonella microfilariae are unsheathed, meaning they do not have a protective covering or sheath. This characteristic distinguishes them from other types of microfilariae, which may have a sheath.
15.
Which of the following are possible clinical forms of a Mansonella infection.
Correct Answer(s)
A. Asymptomatic
B. Pruritis
C. Calabar-like swellings
Explanation
Possible clinical forms of a Mansonella infection include asymptomatic cases, where the individual shows no symptoms of the infection. Pruritis, which refers to intense itching of the skin, can also be a clinical form. Additionally, Calabar-like swellings, characterized by localized painful swellings, can occur in Mansonella infections. Facial edema, or swelling of the face, is not typically associated with Mansonella infections.
16.
Which of the following are Mansonella perstans vectors?
Correct Answer
C. Culicoides midge
Explanation
Culicoides midges are known vectors of Mansonella perstans. Mansonella perstans is a parasitic worm that causes a condition known as mansonelliasis in humans. The Culicoides midge is a small biting insect that is commonly found in tropical and subtropical regions. These midges have been identified as carriers of the Mansonella perstans parasite and play a role in transmitting the infection to humans. Therefore, Culicoides midges are considered to be vectors of Mansonella perstans.
17.
Mansonella streptocerca can be diagnosed with a skin snip.
Correct Answer
A. True
Explanation
Streptocerca causes a subcutaneous filariasis, unlike perstans and ozzardi which cause a cavity filariasis.
18.
A microfilaria with a loose sheath, nuclei to its tail tip, bent tail and bigger than 250 microns is
Correct Answer
B. Loa loa
Explanation
Loa loa is the correct answer because it is the only microfilaria that possesses all the mentioned characteristics. Loa loa has a loose sheath, nuclei that extend to its tail tip, a bent tail, and a size larger than 250 microns. W.bancrofti, M.streptocerca, and O.volvulus do not exhibit all of these characteristics, making them incorrect choices.
19.
Loa loa microfilariae have a diurnal periodicity
Correct Answer
A. True
Explanation
10 am - 2 pm.
20.
Mansoni mosquitoes are vectors of Brugia malayi.
Correct Answer
A. True
Explanation
Other Brugia vectors are Anopheles and Aedes.
21.
What do patients have to be monitored for when given DEC for Loa loa
Correct Answer
C. Brain inflammation
Explanation
Patients have to be monitored for brain inflammation when given DEC for Loa loa. This is because DEC (diethylcarbamazine) is an antiparasitic medication used to treat Loa loa infection, which is caused by a parasitic worm. Brain inflammation, also known as encephalitis, is a potential side effect of DEC treatment. Monitoring for this complication is important to ensure the safety and well-being of the patient.
22.
An unsheathed micofilaria, small at x100 (less than 250 microns), nuclei to its tail tip and a bent tail is Mansonella perstans
Correct Answer
B. False
Explanation
If the tail is bent, it is likely to be streptocerca, although this is the only difference.
23.
A calabar swelling is caused by angioedema.
Correct Answer
A. True
Explanation
A calabar swelling is indeed caused by angioedema. Angioedema is a condition characterized by swelling beneath the skin, often around the face, lips, and throat. Calabar swelling specifically refers to a localized swelling that is typically painless and can occur in various parts of the body. This swelling is commonly associated with angioedema, which can be caused by allergic reactions, certain medications, or underlying medical conditions. Therefore, the statement "A calabar swelling is caused by angioedema" is true.
24.
What is used to treat Mansonella ozzardi?
Correct Answer
B. Single dose of ivermectin
Explanation
Mansonella ozzardi is a parasitic infection caused by a worm. The most effective treatment for this infection is a single dose of ivermectin. Ivermectin is an antiparasitic medication that works by killing the parasites in the body. It is a safe and effective treatment option for Mansonella ozzardi and has been proven to be successful in eliminating the infection. Other medications like DEC and albendazole may be used for different types of parasitic infections, but they are not specifically indicated for treating Mansonella ozzardi.
25.
Transient punctate keratitis is a clinical manifestation of infection with Brugia.
Correct Answer
B. False
Explanation
It is a manifestation of Onchocerciasis. With optic atrophy, it causes blindness.