1.
Supplementation with _______________enhances cerebral and cognitive functions
Correct Answer
C. Vitamin B12
Explanation
Supplementation with Vitamin B12 enhances cerebral and cognitive functions. Vitamin B12 plays a crucial role in the production of red blood cells and the functioning of the nervous system. It helps in the synthesis of DNA and promotes the production of neurotransmitters, which are essential for brain function. Vitamin B12 deficiency can lead to neurological symptoms like memory loss, confusion, and difficulty concentrating. Therefore, supplementing with Vitamin B12 can improve cerebral and cognitive functions.
2.
High levels of Folate is a strong predisposing factor of poor outcome with anti-depressant therapy
Correct Answer
B. False
Explanation
The statement suggests that high levels of Folate are a strong predisposing factor for poor outcome with anti-depressant therapy. However, the given answer is False, which means that high levels of Folate are not a strong predisposing factor for poor outcome with anti-depressant therapy.
3.
The advantage of Rapid disintegration of PACITANE tablets are the following ( Multiple choice)
Correct Answer(s)
A. Allows dissolution in oral cavity without water
B. Have smooth esopHageal movement and less retention with just saliva
D. Suitable for patients of SchizopHrenia
Explanation
The advantage of rapid disintegration of PACITANE tablets is that they allow dissolution in the oral cavity without water, which means that they can be taken easily and conveniently without the need for water. Additionally, these tablets have smooth esophageal movement and less retention with just saliva, making them easier to swallow and reducing the risk of them getting stuck in the throat. Lastly, rapid disintegration tablets are suitable for patients with schizophrenia, as they may have difficulty swallowing or may not be able to take the tablet with water due to their condition.
4.
The process change adopted in PACITANE is Wet granulation to Direct Compression
Correct Answer
A. True
Explanation
The process change adopted in PACITANE is from wet granulation to direct compression. This means that the previous method of wet granulation, which involves mixing the active ingredient with a liquid binder and then drying and granulating the mixture, has been replaced with direct compression. Direct compression is a simpler and more efficient method where the active ingredient is directly compressed into tablets without the need for granulation. This change in process can result in cost savings and improved product quality.
5.
Premature withdrawl comparison of Amisulpride Vs Olanzepine was studied by
Correct Answer
D. Martin S et al
Explanation
Martin S et al studied the premature withdrawal comparison of Amisulpride vs Olanzapine.
6.
The potency of transporter and/or receptor binding can theoretically predict __________ and ________ of anti-depressants
Correct Answer
B. Clinical efficacy and side effect profile
Explanation
The potency of transporter and/or receptor binding can theoretically predict the clinical efficacy and side effect profile of anti-depressants. This means that the strength of the binding between the drug and the transporter or receptor can give an indication of how effective the drug will be in treating depression, as well as what potential side effects it may have. By understanding the potency of the drug's binding, researchers and clinicians can make informed decisions about which anti-depressants to prescribe to patients based on their desired clinical outcomes and potential side effects.
7.
The dosage of PRESTIQ used in Tourian et al is
Correct Answer
C. 200- 400mg
Explanation
The correct answer is 200-400mg. This is because the study conducted by Tourian et al used a dosage range of 200-400mg for the medication PRESTIQ. This dosage range was likely determined based on previous research and clinical trials, which found that this range was effective and safe for the treatment of the condition being studied.
8.
The following statements are true regarding ATIVAN ( Multiple Choice)
Correct Answer(s)
A. Rapid anxiolytic
B. Excellent Calming & sedation
C. Safe co-prescription
D. Relatively cardio-pulmonary-Hepato safety
Explanation
ATIVAN is a medication that has multiple positive attributes. It is known for its rapid anxiolytic effects, meaning it quickly reduces anxiety. Additionally, it provides excellent calming and sedation properties, helping individuals feel relaxed and at ease. It is safe to be co-prescribed with other medications, allowing for potential combination therapies. Furthermore, ATIVAN has relatively low risks in terms of its impact on the cardiovascular, pulmonary, and hepatic systems, making it a safer option for individuals with underlying health conditions in these areas.
9.
The study on remission rates in acute phase treatment was made by
Correct Answer
A. Leibowitz et al 2008
Explanation
Leibowitz et al 2008 conducted the study on remission rates in acute phase treatment.
10.
__________ % of relapse free patients in case of Nasr et al study is
Correct Answer
B. 69 %
Explanation
In the Nasr et al study, 69% of the patients were found to be relapse-free. This means that almost seven out of ten patients did not experience a relapse of their condition. The study likely assessed the effectiveness of a certain treatment or intervention in preventing relapses, and the high percentage suggests that it was successful in a significant number of cases.
11.
Clinician-rated inventory for depressive symptomatology (IDS-C) measure how many items of anxiety cluster
Correct Answer
C. 8 items
Explanation
The clinician-rated inventory for depressive symptomatology (IDS-C) measures 8 items of the anxiety cluster. This means that the inventory assesses various symptoms related to anxiety, such as feelings of restlessness, nervousness, and worry. By evaluating these specific items, clinicians can gain insight into the severity and presence of anxiety symptoms in individuals with depressive symptomatology.
12.
80% of 5-HTT receptor occupancy is necessary for SSRI treatment
Correct Answer
A. True
Explanation
An explanation for the given correct answer is that SSRI (Selective Serotonin Reuptake Inhibitor) treatment requires a minimum of 80% occupancy of the 5-HTT receptors. These receptors are responsible for regulating the levels of serotonin in the brain. By inhibiting the reuptake of serotonin, SSRIs increase its concentration in the synaptic cleft, leading to improved mood and reduced symptoms of depression. Therefore, achieving at least 80% occupancy of the 5-HTT receptors is necessary for the therapeutic effects of SSRIs.
13.
The number of anti-depressants used in Nasr et al study are
Correct Answer
A. 6 anti-depressants
Explanation
The correct answer is 6 anti-depressants. This means that in the study conducted by Nasr et al, a total of 6 different anti-depressant medications were used. The number of anti-depressants used in a study is an important factor as it can impact the validity and generalizability of the findings. Having a larger number of anti-depressants allows for a more comprehensive evaluation of the effectiveness and side effects of different medications, providing a more robust understanding of their overall efficacy.
14.
The study on lesser dropouts of Amisulpride Vs Olanzepine was mde by Sechter et al
Correct Answer
B. False
Explanation
The given statement is false. The study on lesser dropouts of Amisulpride Vs Olanzepine was not made by Sechter et al.
15.
The study Soares et al in Visual aid is present in
Correct Answer
A. Pop-up of Slide 5 ( prestiq)
16.
_____________improvement in patient-related symptom check list (Boyer et al)
Correct Answer
C. 68%
Explanation
The given correct answer of 68% suggests that there was a significant improvement in the patient-related symptom checklist based on the study conducted by Boyer et al. This means that a majority of the patients experienced positive changes in their symptoms after following the checklist. The improvement rate of 68% indicates that the intervention or treatment mentioned in the study had a substantial impact on the patients' symptoms.
17.
The tag line for PRESITQ is
Correct Answer
B. Ready for re-emergence
Explanation
The tagline "Ready for re-emergence" suggests that PRESITQ is prepared and equipped to handle any challenges or changes that may arise. It implies that the company is adaptable and ready to face new opportunities or situations with confidence and certainty. This tagline conveys a sense of readiness and preparedness, which can be appealing to potential customers or clients.
18.
87% of depressed patients present significant impairment in four domains
Correct Answer
A. True
Explanation
The given statement indicates that 87% of depressed patients experience significant impairment in four domains. This suggests that a large majority of individuals with depression face difficulties in various areas of their life, such as work, relationships, daily functioning, and overall well-being. The answer "True" confirms the accuracy of this statement.
19.
The dose adjustment of PRETIQ is required in severe hepatic impairment
Correct Answer
B. False
Explanation
The statement is false because the dose adjustment of PRETIQ is not required in severe hepatic impairment.
20.
Mean weight gain by Amisulpride Vs Olanzepine is
Correct Answer
B. 2.9 kg Vs 5.5 kg
Explanation
The mean weight gain by Amisulpride is 2.9 kg, while the mean weight gain by Olanzepine is 5.5 kg.