Osteoporosis Quiz (Exam Mode) By RNpedia.com

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Osteoporosis Quiz (Exam Mode) By Rnpedia.Com - Quiz

Choose the letter of the correct answer. You have 20 mins. To answer the questions.

Questions and Answers

1.

Estrogen replacement therapy is contraindicated for use in which type of women?
- A.
  
  Women who are prone to osteoporosis
- B.
  
  Women who have high risk of developing breast cancer
- C.
  
  Women who are prone to heart disease
- D.
  
  Women who have high cholesterol levels
Correct Answer
B. Women who have high risk of developing breast cancer

Explanation
Estrogen replacement therapy is contraindicated for use in women who have a high risk of developing breast cancer. This is because estrogen can stimulate the growth of breast tissue, which may increase the risk of developing breast cancer. Therefore, it is important to consider the individual's risk factors for breast cancer before initiating estrogen replacement therapy.

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2.

Which tool is known as 'Gold Standard' for diagnosing osteoporosis?
- A.
  
  Biochemical markers of bone
- B.
  
  X-ray
- C.
  
  Ultra sound of heel
- D.
  
  Dual energy x-ray absorptiometry
Correct Answer
D. Dual energy x-ray absorptiometry

Explanation
Dual energy x-ray absorptiometry (DXA) is known as the "Gold Standard" for diagnosing osteoporosis because it is the most accurate and widely used method for measuring bone mineral density (BMD). DXA uses low-dose x-rays to scan the spine, hip, or other bones to determine the amount of mineral content in the bones. It provides precise measurements of BMD, allowing for early detection and monitoring of osteoporosis. Other tools mentioned, such as biochemical markers of bone, x-ray, and ultrasound of heel, may provide additional information but are not as accurate or reliable as DXA in diagnosing osteoporosis.

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3.

Intervention to prevent osteoporosis in women should start at which age?
- A.
  
  Below 10 years
- B.
  
  20-35 years
- C.
  
  35-45 years
- D.
  
  Above 45 years
Correct Answer
B. 20-35 years

Explanation
Preventing osteoporosis in women is crucial for maintaining bone health and reducing the risk of fractures later in life. The age range of 20-35 years is considered the optimal time to intervene and prevent osteoporosis. During these years, women reach peak bone mass, and interventions such as adopting a healthy lifestyle, including regular exercise, adequate calcium and vitamin D intake, and avoiding smoking and excessive alcohol consumption, can help maximize bone density. Starting interventions at this age can have a significant impact on reducing the risk of osteoporosis and related fractures in later years.

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4.

Osteoporosis is a disorder of?
- A.
  
  Decreased bone mass
- B.
  
  Decreased estrogen level
- C.
  
  Autoimmune disorder
- D.
  
  All of the above
Correct Answer
A. Decreased bone mass

Explanation
Osteoporosis is a disorder characterized by decreased bone mass, leading to weakened and brittle bones. This condition occurs when the body loses too much bone, fails to make enough bone, or both. As a result, the bones become porous and prone to fractures. Decreased bone mass is the primary characteristic of osteoporosis, making it the correct answer. Decreased estrogen levels and autoimmune disorders can contribute to the development of osteoporosis, but they are not the defining features of the disorder.

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5.

Which amongst them is not a risk factor for osteoporosis?
- A.
  
  Post menopausal women
- B.
  
  Asian male
- C.
  
  Smoking
- D.
  
  Asian females
Correct Answer
B. Asian male

Explanation
Asian males are not considered a risk factor for osteoporosis because they generally have higher bone density compared to other ethnic groups. Osteoporosis is more commonly found in postmenopausal women, as the decline in estrogen levels during menopause can lead to bone loss. Smoking is also a risk factor for osteoporosis, as it can decrease bone density. While Asian females may have a higher risk of osteoporosis compared to Asian males, they are still more at risk compared to other ethnic groups.

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6.

Postmenopausal women are more prone to suffer from osteoporosis due to?
- A.
  
  Decreased progesterone level
- B.
  
  Increased Progesterone level
- C.
  
  Decreased oestrogen level
- D.
  
  Increased oestrogen level
Correct Answer
C. Decreased oestrogen level

Explanation
Postmenopausal women are more prone to suffer from osteoporosis due to decreased estrogen levels. Estrogen plays a crucial role in maintaining bone density and strength. After menopause, the ovaries produce less estrogen, leading to a decrease in bone mineral density and an increased risk of osteoporosis. This is because estrogen helps to inhibit bone breakdown and promote bone formation. Therefore, the decrease in estrogen levels in postmenopausal women contributes to the development of osteoporosis.

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7.

What is the name of the trial that showed that alendronate reduces the risk of hip and spinal fractures?
- A.
  
  MORE trial
- B.
  
  FIT trial
- C.
  
  EPIC trial
- D.
  
  PROOF trial
Correct Answer
B. FIT trial

Explanation
The FIT trial is the correct answer because it is a well-known clinical trial that demonstrated the effectiveness of alendronate in reducing the risk of hip and spinal fractures. This trial provided strong evidence for the use of alendronate as a treatment for osteoporosis and has had a significant impact on clinical practice.

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8.

What is the average calcium intake recommended for post menopausal women unable to take estrogen replacement therapy?
- A.
  
  400 mg/day
- B.
  
  200 mg/day
- C.
  
  1500 mg/day
- D.
  
  None of the above
Correct Answer
C. 1500 mg/day

Explanation
The average calcium intake recommended for postmenopausal women unable to take estrogen replacement therapy is 1500 mg/day. This is because postmenopausal women are at a higher risk of developing osteoporosis, and calcium is essential for maintaining bone health. Adequate calcium intake can help reduce the risk of fractures and maintain bone density. Therefore, it is recommended for postmenopausal women to consume 1500 mg of calcium per day to support their bone health.

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9.

Which is not an antiresorptive drug?
- A.
  
  HRT
- B.
  
  Vit D
- C.
  
  Alendronate
- D.
  
  Calcitonin
Correct Answer
B. Vit D

Explanation
Vitamin D is not an antiresorptive drug. Antiresorptive drugs are used to slow down or inhibit the breakdown of bone tissue, whereas vitamin D is essential for the absorption of calcium and phosphorus, which are important for bone health. Vitamin D helps in the regulation of calcium levels in the body, but it does not directly inhibit bone resorption. Therefore, it is not classified as an antiresorptive drug.

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10.

What is the longest duration for which alendronate has been studied in postmenopausal women?
- A.
  
  3 years
- B.
  
  5 years
- C.
  
  7 years
- D.
  
  10 years
Correct Answer
C. 7 years

Explanation
Alendronate has been studied for a duration of 7 years in postmenopausal women. This means that the effects and safety of alendronate have been observed and monitored over a period of 7 years in this specific group of women.

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11.

Alendronate is used in treatment of osteoporosis because it?
- A.
  
  Inhibits osteoclastic activity
- B.
  
  Inhibits osteoblastic activity
- C.
  
  Increases calcium absorption
- D.
  
  Activities PTH
Correct Answer
A. Inhibits osteoclastic activity

Explanation
Alendronate is used in the treatment of osteoporosis because it inhibits osteoclastic activity. Osteoclasts are cells that are responsible for breaking down bone tissue. By inhibiting their activity, alendronate helps to slow down the process of bone loss, which is a characteristic of osteoporosis. This medication helps to increase bone density and reduce the risk of fractures in individuals with osteoporosis.

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12.

Alendronate can be used on which type of osteoporosis?
- A.
  
  Post menopausal osteoporosis
- B.
  
  Male osteoporosis
- C.
  
  Steroid induced osteoporosis
- D.
  
  All of the above
Correct Answer
A. Post menopausal osteoporosis

Explanation
Alendronate is a medication commonly used to treat osteoporosis. It belongs to a class of drugs called bisphosphonates, which work by slowing down the breakdown of bone and increasing bone density. Postmenopausal osteoporosis refers to the type of osteoporosis that occurs in women after menopause, when estrogen levels decrease and bone loss accelerates. Alendronate is particularly effective in treating this type of osteoporosis. While it may also be used in other types of osteoporosis, such as male osteoporosis or steroid-induced osteoporosis, the primary indication for alendronate is postmenopausal osteoporosis.

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Current Version
Mar 21, 2023

Quiz Edited by
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Sep 20, 2013

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RNpedia.com

Osteoporosis Quiz (Exam Mode) By Rnpedia.Com

Estrogen replacement therapy is contraindicated for use in which type of women?

Which tool is known as 'Gold Standard' for diagnosing osteoporosis?

Intervention to prevent osteoporosis in women should start at which age?

Osteoporosis is a disorder of?

Which amongst them is not a risk factor for osteoporosis?

Postmenopausal women are more prone to suffer from osteoporosis due to?

What is the name of the trial that showed that alendronate reduces the risk of hip and spinal fractures?

What is the average calcium intake recommended for post menopausal women unable to take estrogen replacement therapy?

Which is not an antiresorptive drug?

What is the longest duration for which alendronate has been studied in postmenopausal women?

Alendronate is used in treatment of osteoporosis because it?

Alendronate can be used on which type of osteoporosis?