1.
Which of these is not an alternative name for Leptospirosis?
Correct Answer
D. Cattle fever
Explanation
Cattle fever is not an alternative name for Leptospirosis. Leptospirosis is a bacterial infection that is commonly known by alternative names such as Icterohemorrhagic fever, Rice-field fever, and Mud fever. However, Cattle fever refers to a different disease caused by the protozoan parasite Babesia bovis, which affects cattle.
2.
Leptospirosis in human rarely occurs through:
Correct Answer
C. Contact with contaminated human urine
Explanation
Leptospirosis is a bacterial infection that is primarily transmitted through direct or indirect contact with the urine of infected animals. While direct and indirect contact with contaminated animal urine are common modes of transmission, contact with contaminated human urine is not a typical route for the spread of leptospirosis in humans. Therefore, contact with contaminated human urine rarely leads to leptospirosis in humans. Contact with contaminated soil can also be a potential mode of transmission if the soil is contaminated with the urine of infected animals.
3.
Which of these groups is at increased risk of Leptospirosis?
Correct Answer
D. All the above
Explanation
All the groups mentioned (swimmers, sewer workers, and farmers) are at an increased risk of Leptospirosis. Leptospirosis is a bacterial infection that is commonly transmitted through contact with water or soil contaminated with the urine of infected animals. Swimmers are at risk because they may come into contact with contaminated water, while sewer workers are at risk due to their exposure to contaminated sewage. Farmers are also at risk as they often work in environments where they may come into contact with infected animals or contaminated soil. Therefore, all the mentioned groups are at an increased risk of Leptospirosis.
4.
Incubation period for leptospirosis is:
Correct Answer
B. 2 - 16 days
Explanation
The incubation period for leptospirosis is the time between when a person is exposed to the bacteria and when they start showing symptoms. In this case, the correct answer is 2 - 16 days, which means that symptoms can appear as early as 2 days or as late as 16 days after exposure. This range allows for the variability in how quickly the bacteria can multiply and spread in the body, leading to the onset of symptoms.
5.
Ocular manifestations common in anicteric leptospirosis are:
Correct Answer
D. All the above
Explanation
Anicteric leptospirosis refers to a form of leptospirosis where there is no jaundice or yellowing of the skin. Ocular manifestations, or symptoms related to the eyes, are common in this form of the disease. Conjunctival suffusion refers to redness and inflammation of the conjunctiva, the thin membrane that covers the white part of the eye. Retro orbital pain refers to pain behind the eyes. Photophobia is a sensitivity to light. Therefore, all of the above options are correct as they are ocular manifestations commonly seen in anicteric leptospirosis.
6.
Leptospirosis disease is maintained in infected animals by:
Correct Answer
A. Chronic infection of renal tubules
Explanation
Leptospirosis disease is maintained in infected animals through chronic infection of renal tubules. This means that the bacteria causing the disease can persist and reproduce in the renal tubules of infected animals. This chronic infection allows the bacteria to continue to be present in the animal's body, potentially causing recurrent or persistent infections. By colonizing the renal tubules, the bacteria can be shed in the urine, allowing for transmission to other animals or humans.
7.
Which of these statements is not true with regard to leptospires?
Correct Answer
A. They are straight spirochetes
Explanation
Leptospires are not straight spirochetes. They are actually tightly coiled or spiral-shaped bacteria.
8.
In humans leptospires can be detected in:
Correct Answer
D. All of the above
Explanation
Leptospires can be detected in humans in various bodily fluids such as urine, blood, and cerebrospinal fluid. This is because leptospires are bacteria that can infect multiple organs and systems in the body, leading to a systemic infection. The presence of leptospires in these fluids can be indicative of a leptospirosis infection and can be used for diagnostic purposes.
9.
Which of these is not true regarding laboratory findings in anicteric phase of Leptospirosis?
Correct Answer
A. Erythrocyte sedimentation rate (ESR) is reduced
Explanation
During the anicteric phase of Leptospirosis, the erythrocyte sedimentation rate (ESR) is not reduced. This means that the ESR remains normal or may even be elevated. The other laboratory findings mentioned in the options, such as the range of white blood cells (WBC) being below normal to moderately elevated, elevated aminotransferases, and elevated alkaline phosphatases, are all true regarding laboratory findings in the anicteric phase of Leptospirosis.
10.
How many days after infection with leptospires do the urine cultures become positive?
Correct Answer
B. Second week of illness
Explanation
Leptospires are bacteria that cause leptospirosis, a bacterial infection that affects humans and animals. The question asks about the timing of when urine cultures become positive after infection with leptospires. The correct answer is the second week of illness. This means that it takes approximately two weeks after infection for the bacteria to multiply and reach a detectable level in the urine. This information is important for diagnosing and monitoring the progression of leptospirosis.
11.
For isolation of leptospires, blood culture should be taken:
Correct Answer
A. As soon as possible after patient’s presentation
Explanation
The correct answer is "As soon as possible after patient's presentation." This is because leptospires can be detected in the blood during the early stages of infection, typically within the first week. Delaying the blood culture to the second, third, or fourth week may result in a false negative result as the bacteria may no longer be present in the blood. Therefore, it is important to take the blood culture as soon as possible after the patient's presentation to increase the chances of detecting the leptospires.
12.
Cultures for leptospires should be examined for how many weeks before being discarded?
Correct Answer
D. Upto 13 weeks
Explanation
Cultures for leptospires should be examined for up to 13 weeks before being discarded. This is because leptospires can take a long time to grow in culture, and it is important to give them enough time to develop before determining if they are positive or negative. By examining cultures for up to 13 weeks, it allows for a sufficient amount of time for the leptospires to grow and be accurately identified.
13.
Antibodies in blood can be detected how many days after onset of symptoms?
Correct Answer
B. 5 - 7 days
Explanation
Antibodies in blood can be detected 5-7 days after the onset of symptoms. This is because it takes time for the body to produce antibodies in response to an infection. During the first few days of infection, the immune system is still mounting a response and producing antibodies. By the 5-7 day mark, a sufficient amount of antibodies may have been produced and can be detected in the blood through various diagnostic tests.
14.
Antibiotic given to prevent leptospirosis is:
Correct Answer
A. Doxycycline
Explanation
Doxycycline is the correct antibiotic given to prevent leptospirosis. Leptospirosis is a bacterial infection caused by the bacteria Leptospira. Doxycycline is effective against a wide range of bacteria, including Leptospira. It is commonly used as a prophylactic treatment for individuals at risk of contracting leptospirosis, such as those who work in environments with potential exposure to contaminated water or animals. Doxycycline works by inhibiting the growth and spread of bacteria, thus preventing the development of the infection. Ampicillin, Penicillin, and Erythromycin are not effective against Leptospira and are not commonly used for preventing leptospirosis.
15.
Anicteric leptospirosis is treated with:
Correct Answer
D. Any of the above
Explanation
Anicteric leptospirosis, which is a mild form of the disease, can be treated with any of the given options: Doxycycline 100 mg bid, Ampicillin 500-750 mg bid, or Amoxicillin 500 mg bid. The choice of treatment may depend on factors such as the patient's medical history, allergies, and the specific strain of leptospirosis. It is important to consult a healthcare professional for a proper diagnosis and to determine the most appropriate treatment option.