1.
In sechter et al study, AMISULpHRIDE has been compared with
Correct Answer
B. RISPIRIDONE
Explanation
In the study conducted by Sechter et al, the drug AMISULPHRIDE was compared with OLANZEPINE, RISPIRIDONE, HALOPERIDOL, and NOTA. The correct answer, RISPIRIDONE, suggests that the study specifically compared the effectiveness or other aspects of AMISULPHRIDE with RISPIRIDONE. The comparison may have been based on factors such as efficacy, side effects, or other relevant outcomes.
2.
pHENYTOIN CROSSES BBB
Correct Answer
A. True
Explanation
Phenytoin is a medication that is known to cross the blood-brain barrier (BBB). The blood-brain barrier is a protective barrier in the brain that prevents certain substances from entering the brain tissue. However, some medications, like phenytoin, are able to cross this barrier and reach the brain. This is important for phenytoin because it is commonly used as an anticonvulsant medication to treat seizures, and it needs to reach the brain in order to be effective. Therefore, the statement that phenytoin crosses the BBB is true.
3.
AMISULpHRIDE can be given for the children below 18 years of age
Correct Answer
B. False
Explanation
AMISULPHRIDE cannot be given to children below 18 years of age.
4.
The process change in PACITANE is
Correct Answer
B. Wet granulation to direct compression
Explanation
The correct answer is "wet granulation to direct compression." This means that the process in PACITANE has changed from using wet granulation to using direct compression. Wet granulation is a process where the active pharmaceutical ingredient and excipients are mixed with a liquid binder to form granules, which are then dried and compressed into tablets. Direct compression, on the other hand, involves directly compressing the blend of active ingredient and excipients into tablets without the need for wet granulation. This change in process may have been implemented to improve efficiency, reduce production time, or enhance the stability or bioavailability of the drug.
5.
The composisiton of pHENYTOIN in DILANTIN injection is
Correct Answer
A. 100mg /2ml
Explanation
The correct answer is 100mg/2ml. This means that each 2ml of DILANTIN injection contains 100mg of PHENYTOIN.
6.
The clinical trail- CLAYTON et-al study has been conducted for
Correct Answer
D. 12 weeks
Explanation
The clinical trial conducted by Clayton et al. lasted for 12 weeks. This duration was likely chosen to allow for a sufficient amount of time to observe and evaluate the effects of the treatment or intervention being tested. A longer trial period can provide more accurate and reliable data regarding the safety and efficacy of the treatment, as it allows for a better understanding of any potential long-term effects or benefits. Additionally, a 12-week trial duration may also be necessary to assess any potential side effects or adverse reactions that may occur over an extended period of time.
7.
Response to DILANTIN injection will be noted within _______
Correct Answer
D. 20 min
Explanation
The response to DILANTIN injection will be noted within 20 minutes. This means that after administering the injection, the effects or changes resulting from the medication will start to become apparent within a relatively short period of time, specifically within 20 minutes.
8.
______________ corrects the deficiencies caused due to METFORMIN
Correct Answer
C. Vitamin B12
Explanation
Vitamin B12 corrects the deficiencies caused due to METFORMIN. Metformin is a medication commonly used to treat type 2 diabetes, but it can lead to a deficiency in vitamin B12. Vitamin B12 is important for the proper functioning of the nervous system and the production of red blood cells. Therefore, taking vitamin B12 supplements can help correct the deficiencies caused by metformin and ensure that the body has enough of this essential vitamin.
9.
The disintegration time has been increased from 10-15 min to 1 min in case of NEW PACITANE
Correct Answer
B. False
Explanation
The statement is false because it states that the disintegration time has been increased from 10-15 min to 1 min in the case of NEW PACITANE. However, if the disintegration time has been increased, it would mean that it takes longer for the medication to disintegrate, not shorter. Therefore, the correct answer is false.
10.
The following are the advantages of the rapidly disintegrating PACITANE TABLETS ( select all that apply)
Correct Answer(s)
A. Allow dissolution in the oral cavity without water
B. Have smooth esopHageal movement and less retention
D. Are suitable for paranoid patients of SchizopHrenia
Explanation
The rapidly disintegrating PACITANE TABLETS have the advantage of allowing dissolution in the oral cavity without water. This means that patients can take the medication easily and conveniently, even without access to water. These tablets also have the advantage of smooth esophageal movement and less retention, which means that they are less likely to cause discomfort or get stuck in the esophagus. Additionally, these tablets are suitable for paranoid patients of Schizophrenia, indicating that they are specifically designed to meet the needs of this particular patient population.
11.
Patients with mood disorders are more responsive to pain
Correct Answer
B. False
Explanation
The statement "Patients with mood disorders are more responsive to pain" is false. Research has shown that individuals with mood disorders, such as depression or anxiety, may actually experience a decreased sensitivity to pain. This could be due to alterations in the brain's pain processing pathways or the presence of certain neurotransmitters that can dampen pain signals. Therefore, it is incorrect to say that patients with mood disorders are more responsive to pain.
12.
LEVEFREE is a ____________ type of tablet
Correct Answer
B. Film-coated
Explanation
A film-coated tablet refers to a tablet that has a thin layer of a polymeric material applied to its surface. This coating helps to protect the tablet from moisture, light, and air, as well as to improve the tablet's appearance and make it easier to swallow. Therefore, LEVEFREE being a film-coated tablet means that it has a thin layer of a polymeric material applied to its surface.
13.
PACITANE is recommended in patients with TD without concomitane Parkinson's disease
Correct Answer
B. False
Explanation
PACITANE is not recommended in patients with TD without concomitant Parkinson's disease.
14.
The maximum dose of AMISANT administered once daily (per dose) at oral dose is up to ______
Correct Answer
B. 300mg
Explanation
The maximum dose of AMISANT administered once daily at an oral dose is 300mg.
15.
The loading dose of DILANTIN injection in case of status epilepticus is
Correct Answer
C. 10-15mg/kg
Explanation
The loading dose of DILANTIN injection in case of status epilepticus is 10-15mg/kg. This means that for every kilogram of the patient's body weight, a dose of 10-15mg of DILANTIN should be administered. This loading dose is necessary to quickly reach therapeutic levels of the medication in the bloodstream in order to control the seizures associated with status epilepticus.
16.
The initial dose of DAXID (sertraline) in case of Depression & OCD is
Correct Answer
B. 50mg
Explanation
The initial dose of DAXID (sertraline) for depression and OCD is 50mg. This dose is commonly prescribed as it is effective for most patients and has a lower risk of side effects compared to higher doses. Starting with a lower dose allows for monitoring of the patient's response and adjustment of the dosage if necessary.
17.
Co-occurring diabetes & alcohol abuse may complicate neuropathy
Correct Answer
A. True
Explanation
Co-occurring diabetes and alcohol abuse can indeed complicate neuropathy. Diabetes can cause damage to the nerves, leading to neuropathy, and alcohol abuse can further worsen this condition. Alcohol can have toxic effects on the nerves and can also impair the body's ability to regulate blood sugar levels, which can further exacerbate neuropathy in individuals with diabetes. Therefore, it is true that the co-occurrence of diabetes and alcohol abuse can complicate neuropathy.
18.
The size reduction & weight reduction in case of new PACITANE is ______ & ________ respectively
Correct Answer
B. 13% & 30%
Explanation
The correct answer is 13% & 30%. This means that the new PACITANE has a 13% reduction in size and a 30% reduction in weight compared to its previous version.
19.
AMISANT can be administered to the patients of below 18 years of age
Correct Answer
B. False
Explanation
AMISANT cannot be administered to patients below 18 years of age.