1.
Which of the following is the initial treatment regimen for patients with ACS?
Correct Answer
B. MorpHine for pain, oxygen, sublingual or IV nitroglycerin, soluble aspirin between 162 mg and 325 mg and clopidogrel between 300 mg and 600 mg loading dose
Explanation
The initial treatment regimen for patients with ACS includes morphine for pain, oxygen, sublingual or IV nitroglycerin, soluble aspirin between 162 mg and 325 mg, and clopidogrel between 300 mg and 600 mg loading dose. These medications and interventions are aimed at relieving pain, improving oxygenation, reducing clot formation, and preventing further damage to the heart. Morphine is used for pain relief, oxygen is given to improve oxygen supply to the heart, nitroglycerin helps to relax blood vessels and reduce chest pain, aspirin and clopidogrel are antiplatelet medications that prevent blood clot formation.
2.
What did the recent SOLID-TIMI 52 trial find regarding treatment with darapladib?
Correct Answer
A. Darapladib failed to reduce the risk for coronary events when compared with placebo
Explanation
The recent SOLID-TIMI 52 trial found that treatment with darapladib did not result in a reduction in the risk for coronary events when compared with placebo. This means that darapladib was not effective in decreasing the occurrence of coronary events such as heart attacks or strokes.
3.
In 2012, which medication did the FDA reject as a treatment for patients with ACS?
Correct Answer
A. Rivaroxaban
Explanation
In 2012, the FDA rejected Rivaroxaban as a treatment for patients with ACS. The rejection could have been due to various reasons such as lack of sufficient evidence or data to support its efficacy and safety in treating ACS, potential side effects or risks associated with the medication, or failure to meet the required regulatory standards set by the FDA.
4.
Other than obesity, which of the following health conditions is associated with an increased risk for ACS?
Correct Answer
C. Insomnia
Explanation
Insomnia is associated with an increased risk for ACS (acute coronary syndrome). Insomnia is a sleep disorder characterized by difficulty falling asleep or staying asleep. Chronic insomnia can lead to various health problems, including increased blood pressure, inflammation, and impaired glucose metabolism, which are all risk factors for ACS. Lack of sleep can also contribute to an unhealthy lifestyle, such as poor diet and lack of exercise, further increasing the risk for ACS. Therefore, insomnia is a health condition that can potentially increase the risk for ACS.
5.
Which of the following is the most common symptom of ACS?
Correct Answer
A. Chest pain
Explanation
Chest pain is the most common symptom of ACS (Acute Coronary Syndrome). ACS is a term used to describe a range of conditions caused by a sudden reduction of blood flow to the heart. Chest pain, also known as angina, is often described as a tightness, pressure, or squeezing sensation in the chest. It can also radiate to the arms, shoulders, jaw, or back. Chest pain is a key indicator of a potential heart problem and should be taken seriously, as it could be a sign of a heart attack or unstable angina.
6.
Chest pain that is unpredictable and gets worse even with rest is a symptom of which of the following?
Correct Answer
C. Unstable angina
Explanation
Unstable angina is the correct answer because it is characterized by chest pain that is unpredictable and worsens even with rest. Unstable angina occurs when there is a reduced blood flow to the heart, typically due to a blood clot forming in one of the coronary arteries. This can lead to chest pain or discomfort, which may be severe and can radiate to the left arm, shoulder, or jaw. Unlike stable angina, which is predictable and usually relieved with rest or medication, unstable angina is considered a medical emergency as it can progress to a heart attack.
7.
Which of the following is a test used to diagnose ACS?
Correct Answer
A. ECG
Explanation
ECG (electrocardiogram) is a test used to diagnose ACS (acute coronary syndrome). ACS is a term used to describe a range of conditions that occur due to reduced blood flow to the heart, including heart attack and unstable angina. An ECG measures the electrical activity of the heart and can detect abnormalities in the heart rhythm or signs of damage to the heart muscle. It is a common and effective diagnostic tool for evaluating patients with symptoms suggestive of ACS, such as chest pain or shortness of breath.
8.
Although delays are known to occur throughout emergency ACS care, which patient group is most affected according to results from the IMMEDIATE trial?
Correct Answer
B. Older women
Explanation
The correct answer is older women. According to the results from the IMMEDIATE trial, older women are the patient group that is most affected by delays in emergency ACS care. This suggests that older women may face more challenges or barriers in accessing timely and efficient care during a cardiac emergency compared to other patient groups.
9.
Which trial found that the presence of high-risk plaque detected by coronary CTA in the emergency department was associated with an increased risk for ACS in those with acute chest pain?
Correct Answer
C. ROMICAT - II
Explanation
The ROMICAT - II trial found that the presence of high-risk plaque detected by coronary CTA in the emergency department was associated with an increased risk for ACS in those with acute chest pain.
10.
In 2011, which of the following medications did the FDA approve for the reduction of MI and CV death in patients with ACS?
Correct Answer
A. Ticagrelor
Explanation
Ticagrelor is the correct answer because in 2011, the FDA approved this medication for reducing myocardial infarction (MI) and cardiovascular (CV) death in patients with acute coronary syndrome (ACS). Ticagrelor is an antiplatelet medication that helps prevent blood clots and reduces the risk of heart attack and stroke in patients with ACS. It works by inhibiting platelet aggregation, thereby preventing the formation of blood clots in the arteries. This approval made ticagrelor an important treatment option for patients with ACS, providing them with a medication that can help improve their outcomes and reduce the risk of serious cardiovascular events.