Lipids: Lipid Metabolism Assessment
Questions and Answers
- 1.
Your diet has a direct impact on the type of LDL your body produces. A healthy diet leads to large, bouyant particles and an unhealthy diet leads to a small, dense LDL particles
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
The explanation for the given correct answer is that the type of LDL (low-density lipoprotein) particles produced by the body is influenced by the diet. A healthy diet consisting of nutritious foods can lead to the production of large, buoyant LDL particles. On the other hand, an unhealthy diet that includes high levels of unhealthy fats and sugars can result in the production of small, dense LDL particles. Therefore, the statement is true as the diet directly affects the type of LDL particles produced by the body.Rate this question:
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- 2.
HDL removes surplus triglycerides from the periphery and transports it to the liver for disposal
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
HDL, or high-density lipoprotein, is often referred to as the "good" cholesterol because it helps remove excess cholesterol from the bloodstream and transport it to the liver for disposal. However, HDL does not remove surplus triglycerides. Instead, it primarily removes excess cholesterol from cells and tissues. Triglycerides, on the other hand, are transported by a different type of lipoprotein called VLDL (very low-density lipoprotein). Therefore, the statement that HDL removes surplus triglycerides from the periphery and transports it to the liver for disposal is false.Rate this question:
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- 3.
________packages the fat we consume and transports it from our small intestine to the liver.
- A.
LDL
- B.
VLDL
- C.
Chylomicrons
- D.
HDL
Correct Answer
C. ChylomicronsExplanation
Chylomicrons are responsible for packaging and transporting the fat we consume from our small intestine to the liver. They are large lipoprotein particles that are formed in the intestinal cells after we eat a meal. Chylomicrons contain dietary triglycerides, cholesterol, and fat-soluble vitamins. They are released into the lymphatic system and eventually enter the bloodstream, where they deliver the dietary fat to various tissues, including the liver. Once the fat is delivered, chylomicrons are broken down and removed from the bloodstream. Therefore, chylomicrons play a crucial role in the absorption and transport of dietary fat in our body.Rate this question:
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- 4.
_______is(are) a class of lipoproteins formed in the degradation of very-low-density lipoproteins; some are cleared rapidly into the liver and some are degraded to low-density lipoproteins.
- A.
IDL
- B.
Remnants lipoproteins
- C.
HDL
- D.
VLDL3
Correct Answer
A. IDLExplanation
IDL (intermediate-density lipoproteins) are a class of lipoproteins formed in the degradation of very-low-density lipoproteins (VLDL). Some IDL are cleared rapidly into the liver, while others are degraded to low-density lipoproteins (LDL). This means that IDL play a role in the transport and metabolism of cholesterol and triglycerides in the body.Rate this question:
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- 5.
Their levels are genetically determined and remain relatively stable over an individual's lifetime.
- A.
Small, dense LDL
- B.
Lp(a)
- C.
LpPla2
- D.
IDL
Correct Answer
B. Lp(a)Explanation
Lp(a) levels are genetically determined and remain relatively stable over an individual's lifetime. This means that an individual's genetic makeup determines their Lp(a) levels, and these levels do not fluctuate significantly throughout their life. Other factors such as diet and lifestyle may influence the overall levels of lipoproteins in the body, but Lp(a) specifically is primarily determined by genetics.Rate this question:
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- 6.
__________transport cholesterol from the tissues of the body back to the liver through a process called reverse cholesterol transport, so the cholesterol can be eliminated in the bile.
- A.
LDL
- B.
Chylomicrons
- C.
Triglycerides
- D.
Phopholipids
- E.
HDL
Correct Answer
E. HDLExplanation
HDL (high-density lipoprotein) is responsible for transporting cholesterol from the tissues of the body back to the liver through a process called reverse cholesterol transport. This process allows the cholesterol to be eliminated in the bile. Unlike LDL (low-density lipoprotein), which carries cholesterol to the tissues and can contribute to the buildup of plaque in the arteries, HDL helps to remove cholesterol from the body, promoting heart health. Chylomicrons, triglycerides, and phospholipids are not specifically involved in reverse cholesterol transport.Rate this question:
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- 7.
__________transports cholesterol to the tissues of the body. It is therefore considered the "bad" cholesterol.
- A.
IDL
- B.
Lp(a)
- C.
VLDL3
- D.
LDL
Correct Answer
D. LDLExplanation
LDL (low-density lipoprotein) transports cholesterol to the tissues of the body. It is considered the "bad" cholesterol because high levels of LDL can lead to the buildup of cholesterol in the arteries, increasing the risk of heart disease and stroke. LDL is often referred to as "bad" cholesterol because it can contribute to the formation of plaque in the arteries, leading to atherosclerosis.Rate this question:
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- 8.
Of the lipoprotein types produced by the liver, ______contains the highest amount of triglyceride. Because it contains a high level of triglyceride, having a high level means you may have an increased risk of coronary artery disease
- A.
VLDL
- B.
VLDL3
- C.
IDL
- D.
LDL
Correct Answer
A. VLDLExplanation
VLDL (Very Low-Density Lipoprotein) contains the highest amount of triglyceride among the lipoprotein types produced by the liver. This high level of triglyceride in VLDL is associated with an increased risk of coronary artery disease.Rate this question:
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- 9.
Please select all the lipoproteins that occurs as part of a healthy diet lipid pathways
- A.
VLDL
- B.
VLDL3
- C.
LDL Large, Bouyant
- D.
IDL
- E.
HDL
Correct Answer(s)
A. VLDL
C. LDL Large, Bouyant
D. IDL
E. HDLExplanation
VLDL, LDL Large, Bouyant, IDL, and HDL are all lipoproteins that occur as part of a healthy diet lipid pathways. VLDL (Very Low-Density Lipoprotein) transports triglycerides from the liver to peripheral tissues. LDL (Low-Density Lipoprotein) carries cholesterol to cells and is often referred to as "bad" cholesterol. LDL Large, Bouyant refers to a specific subtype of LDL that is less dense and associated with a lower risk of cardiovascular disease. IDL (Intermediate-Density Lipoprotein) is a precursor to LDL. HDL (High-Density Lipoprotein) is known as "good" cholesterol as it helps remove excess cholesterol from the bloodstream.Rate this question:
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- 10.
Which of the following are unique to an unhealthy diet lipid metabolism pathway?
- A.
Lp(a)
- B.
HDL
- C.
VLDL3
- D.
Small, dense LDL
- E.
Large, bouyant LDL
Correct Answer(s)
C. VLDL3
D. Small, dense LDLExplanation
VLDL3 and small, dense LDL are unique to an unhealthy diet lipid metabolism pathway. VLDL3 refers to very low-density lipoprotein 3, which is a type of lipoprotein that carries triglycerides from the liver to other tissues. Small, dense LDL refers to low-density lipoprotein particles that are smaller and denser than normal LDL particles. These two components are associated with an increased risk of cardiovascular disease and are often found in individuals with an unhealthy diet that is high in saturated fats and cholesterol. HDL and large, buoyant LDL are not unique to an unhealthy diet and can be found in both healthy and unhealthy diets.Rate this question:
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- 11.
Fundamentally, triglycerides provide energy whereas cholesterol supports structure and function
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Triglycerides are a type of fat that serve as a source of energy in the body. They are broken down to release energy when needed. On the other hand, cholesterol is a waxy substance that is important for the structure and function of cells. It is a crucial component of cell membranes and is also used to produce hormones and vitamin D. Therefore, the statement that triglycerides provide energy and cholesterol supports structure and function is true.Rate this question:
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- 12.
Lp(a) is genetically similar to _______________thus promoting clot formation in arteries burdened by atherosclerotic plaque. This may be one of the mechanisms behind the involvement of Lp(a) in heart attack and stroke.
- A.
Fibrolectin
- B.
Fibrinogen
- C.
Plasminogen
- D.
Plasmin
- E.
None of the above
Correct Answer
C. PlasminogenExplanation
Lp(a) is genetically similar to plasminogen, which is a protein involved in the breakdown of blood clots. However, Lp(a) does not have the same ability to break down blood clots as plasminogen. Instead, Lp(a) promotes clot formation in arteries that are already burdened by atherosclerotic plaque. This can contribute to the development of heart attacks and strokes, as blood clots can block blood flow to the heart or brain. Therefore, the involvement of Lp(a) in heart attack and stroke may be due to its similarity to plasminogen and its role in promoting clot formation.Rate this question:
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- 13.
Which of the following statements are true regarding lipoprotein particles and atherosclerosis?
- A.
Smaller particles more easily infiltrate the vessel wall, initiating the atherosclerotic process
- B.
More particles means more opportunity for infiltration to occur.
- C.
Higher cholesterol content can result in a more rapid advancement in atherosclerosis.
- D.
All of the above are true
Correct Answer
D. All of the above are trueExplanation
Smaller lipoprotein particles can more easily penetrate the vessel wall, initiating the process of atherosclerosis. This is because smaller particles have a higher chance of entering the endothelial layer of the blood vessels. Additionally, a higher number of lipoprotein particles increases the opportunity for infiltration to occur, leading to atherosclerosis. Moreover, lipoprotein particles with higher cholesterol content can contribute to a more rapid advancement of atherosclerosis, as cholesterol can promote the formation of plaques in the vessel walls. Therefore, all of the statements mentioned in the question are true regarding lipoprotein particles and atherosclerosis.Rate this question:
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- 14.
Regular aerobic exercise, loss of excess weight (fat), and cessation of cigarette smoking may increase HDL cholesterol levels.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Regular aerobic exercise, loss of excess weight (fat), and cessation of cigarette smoking are all lifestyle changes that have been shown to positively impact HDL cholesterol levels. HDL cholesterol, also known as "good" cholesterol, helps to remove excess cholesterol from the bloodstream and carries it back to the liver where it can be broken down and excreted. Regular exercise can increase HDL cholesterol levels by improving the body's ability to transport and metabolize fats. Losing excess weight can also lead to an increase in HDL cholesterol levels. Additionally, quitting smoking has been shown to raise HDL cholesterol levels. Therefore, it is true that these lifestyle changes can increase HDL cholesterol levels.Rate this question:
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- 15.
An HDL cholesterol of _______or higher gives some protection against heart disease
- A.
40 mg/dl
- B.
60 mg/dl
- C.
50 mg/dl
- D.
30 mg/dl
Correct Answer
B. 60 mg/dlExplanation
An HDL cholesterol level of 60 mg/dl or higher gives some protection against heart disease. Higher levels of HDL cholesterol are associated with a lower risk of developing heart disease because HDL cholesterol helps remove LDL cholesterol (the "bad" cholesterol) from the arteries, preventing the buildup of plaque. Therefore, having a higher HDL cholesterol level is considered beneficial for heart health.Rate this question:
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- 16.
Lp(a) is considered to be ____ more atherogenic (disease causing) than LDL cholesterol.
- A.
100X
- B.
50X
- C.
10X
- D.
15X
Correct Answer
C. 10XExplanation
Lp(a) is considered to be 10 times more atherogenic (disease causing) than LDL cholesterol. This means that Lp(a) is ten times more likely to contribute to the development of atherosclerosis, which is the buildup of plaque in the arteries. This increased atherogenicity of Lp(a) makes it a significant risk factor for cardiovascular disease.Rate this question:
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- 17.
What 2 lipoprotein particles are not present in the HEALTHY LDL metabolic Pathway:
- A.
IDL & VLDL
- B.
VLDL & LDL Type A
- C.
HDL & LP(a)
- D.
LDL Type B, IDL
- E.
None of the above
Correct Answer
E. None of the aboveExplanation
The correct answer is "None of the above". This means that all of the lipoprotein particles mentioned in the options (IDL, VLDL, LDL Type A, HDL, LP(a), LDL Type B) are present in the healthy LDL metabolic pathway.Rate this question:
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- 18.
What statements are true concerning the LDL metabolic pathway?
- A.
As particles progress along the pathway, their cholesterol load increases as a percent of total load
- B.
As particles progress along the pathway, their triglyceride load decreases as a percent of total load
- C.
As particles progress along the pathway, their apoprotein concentration increases as a percent of total
- D.
All of the statements are correct
- E.
A and B only are correct
Correct Answer
D. All of the statements are correctExplanation
The LDL metabolic pathway involves the transportation of LDL particles in the body. As these particles progress along the pathway, their cholesterol load increases as a percent of the total load. This means that the LDL particles accumulate more cholesterol as they move along the pathway. Additionally, their triglyceride load decreases as a percent of the total load, indicating that the triglyceride content in the particles decreases. Furthermore, the apoprotein concentration in the particles increases as a percent of the total load, suggesting that the concentration of apoproteins, which play a role in the metabolism of LDL, increases. Therefore, all of the statements are correct.Rate this question:
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- 19.
Elevated Lp(a) presents a far greater risk than elevated LDL because it is both atherogenic and thrombogenic
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Elevated Lp(a) poses a greater risk compared to elevated LDL because it is both atherogenic and thrombogenic. Lp(a) is a type of lipoprotein that can contribute to the development of atherosclerosis, which is the buildup of plaque in the arteries. Additionally, Lp(a) has been shown to promote blood clot formation, making it thrombogenic. Both of these factors increase the risk of cardiovascular diseases, such as heart attacks and strokes. Therefore, the statement that elevated Lp(a) presents a greater risk than elevated LDL is true.Rate this question:
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- 20.
One difference between Chylomicrons and VLDL is that chylomicrons originate from the liver whereas VLDL originates from the small intestines
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
Chylomicrons and VLDL are both types of lipoproteins involved in transporting lipids in the bloodstream. However, the given statement is incorrect. Chylomicrons actually originate from the small intestines, specifically from the cells lining the intestinal wall, after the absorption of dietary fats. On the other hand, VLDL (very low-density lipoprotein) is produced in the liver and contains both triglycerides and cholesterol. Therefore, the correct answer is false.Rate this question:
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- 21.
In unhealthy lipoprotein metabolism (unhealthy eating), more particles are created than the body can use and remove, causing a greater particle load to progress through the metabolic pathway, with the particles getting progressively more cholesterol-rich throughout the process. This leads to an increased number of particles that are high in cholesterol, thus increasing the patient’s risk for atherosclerosis.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
In unhealthy lipoprotein metabolism, when a person consumes unhealthy food, more lipoprotein particles are produced in the body than it can effectively utilize and eliminate. This results in an accumulation of lipoprotein particles that become progressively enriched with cholesterol. This increased number of cholesterol-rich particles increases the risk of atherosclerosis, a condition characterized by the buildup of plaque in the arteries. Therefore, the statement "True" is correct as it accurately reflects the relationship between unhealthy lipoprotein metabolism, cholesterol-rich particles, and the increased risk of atherosclerosis.Rate this question:
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- 22.
VLDL and VLDL3 are differentiated by: (mark all that apply)
- A.
Their Size
- B.
Their Relative cholesterol content
- C.
Their Apo Marker
- D.
Their atherogenicity
Correct Answer(s)
A. Their Size
B. Their Relative cholesterol content
D. Their atherogenicityExplanation
VLDL and VLDL3 can be differentiated based on their size, relative cholesterol content, and atherogenicity. Size refers to the physical dimensions of the particles, with VLDL3 being smaller than VLDL. Relative cholesterol content refers to the amount of cholesterol present in each particle, with VLDL3 having a higher cholesterol content compared to VLDL. Atherogenicity refers to the ability of the particles to promote the development of atherosclerosis, with VLDL3 being more atherogenic than VLDL.Rate this question:
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Mar 21, 2023Quiz Edited by
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Jun 10, 2014Quiz Created by
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