Obstetric And Perinatal Infections
Questions and Answers
- 1.
The leading cause of maternal mortality in endemic areas of the southwest US and Latin America is due to what fungal infection?
- A.
Candidiasis
- B.
Malaria
- C.
Poliomyelitis
- D.
Coccidioidomycosis
Correct Answer
D. CoccidioidomycosisExplanation
Coccidioidomycosis is the correct answer because it is a fungal infection that is prevalent in endemic areas of the southwest US and Latin America. This infection, also known as Valley fever, is caused by inhaling spores of the fungus Coccidioides. It can cause a range of symptoms, from mild flu-like symptoms to severe pneumonia. In pregnant women, it can lead to complications such as pneumonia, respiratory distress, and even death, making it a leading cause of maternal mortality in these areas.Rate this question:
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- 2.
Once a fetus is infected, it more more susceptible to infection due to its poor immunity and lack of synthesis of what antibody?
- A.
IgA
- B.
IgD
- C.
IgG
- D.
IgM
Correct Answer
C. IgGExplanation
Once a fetus is infected, it is more susceptible to infection due to its poor immunity and lack of synthesis of IgG antibodies. IgG antibodies are the most abundant type of antibody in the body and they play a crucial role in providing passive immunity to the fetus during pregnancy. These antibodies are transferred from the mother to the fetus through the placenta, providing protection against various infections. However, if the fetus becomes infected, its own immune system is not fully developed and it cannot produce enough IgG antibodies to effectively fight off the infection, making it more susceptible to further infections.Rate this question:
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- 3.
Molecules that can cause cellular defects in growth, i.e. induce fetal malformations, are known as
- A.
Secretagogues
- B.
Teratogens
- C.
Hematotrophic
- D.
Cytopathogenic
Correct Answer
B. TeratogensExplanation
Teratogens are molecules that can cause cellular defects in growth and induce fetal malformations. They are substances or agents that can interfere with the normal development of an embryo or fetus. These molecules can be drugs, chemicals, infections, or even physical factors like radiation. Teratogens can have a wide range of effects on the developing organism, leading to various birth defects or developmental abnormalities. It is important to identify and avoid exposure to teratogens during pregnancy to ensure the healthy development of the fetus.Rate this question:
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- 4.
A distinguishing factor between viral teratogens (rubella) and other teratogens (drugs, radiation) would be that
- A.
Only viral teratogens cause retarded fetal growth
- B.
Fetal death is only a possibility with other teratogens, not viral
- C.
Maternal effects are only seen with viral teratogens
- D.
Genetic factors are not present with viral teratogens
Correct Answer
D. Genetic factors are not present with viral teratogensExplanation
Genetic factors refer to the presence of specific genes or genetic abnormalities that can increase the risk of birth defects or developmental issues in the fetus. In the context of teratogens, genetic factors can interact with other environmental factors to influence the likelihood and severity of birth defects. The given answer suggests that genetic factors are not present with viral teratogens, implying that viral infections during pregnancy do not directly affect the genetic makeup of the fetus. This distinguishes viral teratogens from other teratogens, such as drugs or radiation, which can potentially interact with genetic factors to cause birth defects.Rate this question:
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- 5.
Primary infection of the mother, rather than re-activation, tends to have a worse fetal consequence.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Primary infection of the mother refers to the first time she is exposed to a particular infection. This is usually more severe because her immune system has not encountered the pathogen before and therefore has not developed specific defenses against it. As a result, the infection can have more severe consequences for the fetus. In contrast, reactivation of a previous infection tends to have milder effects because the mother's immune system has already developed some level of immunity to the pathogen. Therefore, the statement that primary infection of the mother tends to have worse fetal consequences is true.Rate this question:
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- 6.
A fetus is particularly susceptible to rubella infection when maternal infection occurs during what stage of pregnancy?
- A.
1st trimester
- B.
2nd trimester
- C.
3rd trimester
- D.
Susceptibility unknown
Correct Answer
A. 1st trimesterExplanation
During the first 3 months, organ development occurs. virus interfere with development of heart, brain, eyes and earsRate this question:
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- 7.
Congenital rubella is associated with the development of what clinical condition in 80% of those infants infected?
- A.
Blindness
- B.
Deafness
- C.
Obesity
- D.
Diabetes mellitus
Correct Answer
B. DeafnessExplanation
Congenital rubella is a viral infection that can be passed from a pregnant woman to her unborn baby. It is known to cause a range of birth defects, with deafness being the most common clinical condition associated with it. Approximately 80% of infants infected with rubella during pregnancy will develop some degree of hearing loss. This is due to the virus affecting the development of the baby's auditory system in the womb. Therefore, deafness is the most likely clinical condition to be associated with congenital rubella infection.Rate this question:
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- 8.
What antibody, produced by the fetus, can be detected in the cord blood of an infant infected with the rubella virus?
- A.
IgA
- B.
IgD
- C.
IgG
- D.
IgM
Correct Answer
D. IgMExplanation
During a rubella virus infection, the fetus produces IgM antibodies, which can be detected in the cord blood of an infected infant. IgM antibodies are the first type of antibodies produced by the immune system in response to an infection. They are typically present in the early stages of an infection and help to activate other immune cells to fight against the virus. Therefore, the presence of IgM antibodies in the cord blood indicates an active rubella virus infection in the infant.Rate this question:
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- 9.
Congenital rubella is completely preventable by
- A.
Isolation
- B.
Vaccination
- C.
Having a superb immune system
Correct Answer
B. VaccinationExplanation
The correct answer is vaccination. Congenital rubella refers to rubella infection in a pregnant woman, which can cause severe birth defects in the baby. Vaccination against rubella is highly effective in preventing the disease. It helps to build immunity in individuals, preventing them from getting infected and transmitting the virus to others, including pregnant women. By vaccinating individuals, especially women of childbearing age, the risk of congenital rubella can be significantly reduced, ultimately preventing the associated birth defects.Rate this question:
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- 10.
A primary CMV infection occurring during the first trimester is associated with sensorineural hearing loss, more specifically associated with what cranial nerve?
- A.
CN IV
- B.
CN V
- C.
CN VI
- D.
CN VIII
Correct Answer
D. CN VIIIExplanation
inner ear - abnormality in the hair cells of the organ of Corti in the cochleaRate this question:
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- 11.
95% of infants infected with congenital CMV infection are symptomatic at birth.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
most are symptomatic. Deafness and mental retardation may not be detectable until later in childhoodRate this question:
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- 12.
Clinical features such as hepatosplenomegaly, skin and mucosal lesions, and a saddle-shaped nose are associated with what congenital infection?
- A.
Congenital rubella
- B.
Congenital CMV
- C.
Congenital syphilis
- D.
Congenital HIV
Correct Answer
C. Congenital sypHilisExplanation
Clinical features such as hepatosplenomegaly, skin and mucosal lesions, and a saddle-shaped nose are commonly seen in individuals with congenital syphilis. This infection is caused by the transmission of the bacteria Treponema pallidum from an infected mother to her fetus during pregnancy. These clinical features can occur due to the systemic spread of the bacteria and the resulting inflammation and damage to various organs and tissues.Rate this question:
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- 13.
Congenital HIV is most likely transmitted to the fetus during what stage or pregnancy?
- A.
First 3 months
- B.
Late pregnancy or during delivery
- C.
No known susceptibility during any stage
Correct Answer
B. Late pregnancy or during deliveryExplanation
Congenital HIV is most likely transmitted to the fetus during late pregnancy or during delivery. This is because the virus can be passed from an HIV-positive mother to her baby through the placenta or during childbirth. Transmission during the first 3 months of pregnancy is less likely because the placenta is not fully developed at that stage, making it harder for the virus to cross the placental barrier. However, it is still important for pregnant women with HIV to receive proper medical care and take necessary precautions to reduce the risk of transmission to their babies.Rate this question:
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- 14.
Congenital HIV infections can be controlled or prevented by
- A.
Offering antiviral drugs during pregnancy
- B.
Having an elective cesarean section
- C.
Avoid breast feeding
- D.
All of the above
Correct Answer
D. All of the aboveExplanation
Congenital HIV infections can be controlled or prevented by offering antiviral drugs during pregnancy, having an elective cesarean section, and avoiding breastfeeding. Antiviral drugs can reduce the viral load in the mother, decreasing the risk of transmission to the fetus. An elective cesarean section can further reduce the risk of transmission during delivery. Finally, avoiding breastfeeding can prevent transmission of the virus through breast milk. Therefore, all of the above options are effective in controlling or preventing congenital HIV infections.Rate this question:
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- 15.
Which of the following must be present In order to positively diagnosis an infant with congenital HIV?
- A.
Anti-HIV
- B.
HIV antigen
- C.
Both Anti-HIV and antigen
- D.
Maternal IgG-Ab
Correct Answer
C. Both Anti-HIV and antigenExplanation
In order to positively diagnose an infant with congenital HIV, both Anti-HIV and antigen must be present. Anti-HIV refers to the antibodies produced by the body in response to HIV infection, while HIV antigen is a protein produced by the virus itself. The presence of both indicates an active HIV infection in the infant, confirming the diagnosis. Maternal IgG-Ab, on the other hand, refers to the maternal antibodies passed on to the infant, which may or may not indicate an actual HIV infection in the infant.Rate this question:
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- 16.
Listeria monocytogenes is classified as a
- A.
Fungus
- B.
Gram negative rod
- C.
Gram positive cocci
- D.
Gram positive rod
Correct Answer
D. Gram positive rodExplanation
Listeria monocytogenes is classified as a gram positive rod because it is a bacterium that appears purple when stained with the Gram stain. Gram positive bacteria have a thick peptidoglycan layer in their cell wall, which retains the crystal violet stain, while gram negative bacteria do not. Listeria monocytogenes is rod-shaped and belongs to the phylum Firmicutes, which includes other gram positive bacteria.Rate this question:
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- 17.
Due to the risk of development of congenital malformations, it is suggested that during pregnancy, women should not consume raw or undercooked meat because
- A.
Listeria is heat resistant
- B.
Listeria can grow at regular refrigeration temperatures
- C.
It will give you morning sickness
- D.
The consumption of excess mercury can be fatal
Correct Answer
B. Listeria can grow at regular refrigeration temperaturesExplanation
During pregnancy, it is important for women to avoid consuming raw or undercooked meat due to the risk of developing congenital malformations. The correct answer states that Listeria can grow at regular refrigeration temperatures. Listeria is a bacteria that can contaminate raw or undercooked meat and can cause a serious infection called listeriosis. This bacteria is able to grow and multiply even in refrigerated temperatures, increasing the risk of infection if the meat is not properly cooked. Therefore, it is crucial for pregnant women to thoroughly cook their meat to kill any potential Listeria bacteria and reduce the risk of listeriosis.Rate this question:
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- 18.
Listeriosis has the potential to cause bacteremia in pregnancy women, which is why treatment with ampicillin may need to be combined with what other medication in order to achieve a bactericidal effect?
- A.
Cephalosporin
- B.
Doxycycline
- C.
Gentamicin
- D.
Interferons
Correct Answer
C. GentamicinExplanation
During pregnancy, Listeriosis can lead to bacteremia in women. Ampicillin is a commonly used antibiotic to treat Listeriosis, but it may not be sufficient on its own to achieve a bactericidal effect. Combining ampicillin with gentamicin can enhance the effectiveness of the treatment. Gentamicin is an aminoglycoside antibiotic that works by inhibiting bacterial protein synthesis, thus aiding in the eradication of the Listeria bacteria. Therefore, combining ampicillin with gentamicin can help achieve a bactericidal effect and effectively treat Listeriosis in pregnant women.Rate this question:
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- 19.
Chorioamnionitis and maternal fever can be the result of bacterial infections caused by colonized flora in the vagina and rectum, such as
- A.
Group A hemolytic streptococci
- B.
Group B hemolytic streptococci
- C.
Candida
- D.
Staph auerus
Correct Answer
B. Group B hemolytic streptococciExplanation
Chorioamnionitis and maternal fever can be caused by bacterial infections, and one of the common bacteria responsible for these infections is group B hemolytic streptococci. This bacterium is commonly found in the vagina and rectum and can lead to inflammation of the fetal membranes and amniotic fluid, resulting in chorioamnionitis. Maternal fever can also occur as a response to this bacterial infection. Therefore, group B hemolytic streptococci is the correct answer in this case.Rate this question:
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- 20.
This is an example of what type of infection that usually causes inflammation and edema of the eye and is more severe?
- A.
Congenital HSV
- B.
Gonococcal ophthalmia neonatorum
- C.
Chlamydia infection
- D.
Staphylococcal infection
Correct Answer
B. Gonococcal opHthalmia neonatorumExplanation
Gonococcal ophthalmia neonatorum is a type of infection that usually causes inflammation and edema of the eye and is more severe. This infection is caused by the bacterium Neisseria gonorrhoeae, which is transmitted from the mother to the newborn during delivery. It can lead to serious complications if not treated promptly, including corneal scarring, vision loss, and systemic infection. Prompt diagnosis and treatment with antibiotics are essential to prevent these complications.Rate this question:
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- 21.
This condition presents clinically with large areas of epidermal loss where bullae have burst due to epidermolytic toxins.
- A.
Congenital HSV
- B.
Gonococcal ophthalmia neonatorum
- C.
Staphylococcal scaled skin syndrome
- D.
Congenital syphilis
Correct Answer
C. StapHylococcal scaled skin syndromeExplanation
Staphylococcal scaled skin syndrome is a condition characterized by large areas of epidermal loss where bullae have burst due to epidermolytic toxins produced by Staphylococcus aureus. This condition typically affects infants and young children, and is caused by a localized infection with the bacteria. The epidermolytic toxins cause the outer layer of the skin to separate and blister, leading to the characteristic appearance of large areas of epidermal loss. This condition is different from other options listed, such as congenital HSV, gonococcal ophthalmia neonatorum, and congenital syphilis, which present with different clinical features and underlying causes.Rate this question:
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Feb 03, 2023Quiz Edited by
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Dec 08, 2012Quiz Created by
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