1.
LOGIN
Enter Username Password
>OSMOSIS_JONES ******
W*E*L*C*O*M*E !
You are logged in as Osmosis Jones, Leucocyte Hero.
You are somewhere among the natural gates and alleys of the body. You sense a darkness.
>INVENTORY
You are carrying:
Lysozyme
Antigen receptors
DNA helicase
Gene-O-Meter(TM)
>LOOK
You are in a huge chamber. Above you in the darkness and far away, a rhythm is generating. You know that at any moment the SAN will cause muscular contraction to sweep you through the only exit, which is the aorta.
You must be in the:
Correct Answer
C. Left ventricle
Explanation
The aorta is the main blood vessel leading from the left atrium.
2.
>LOOK
The contraction of the heart has swept you through the aorta and you are now
powering around the body in the cardiovascular system. You notice in one of the
blood vessels a narrowing where fat inside the artery wall has bulged the
tissue inwards. You radio headquarters and report:
Correct Answer
B. An atheroma
Explanation
The correct answer is An atheroma. An atheroma refers to the narrowing of a blood vessel due to the build-up of fat inside the artery wall, causing the tissue to bulge inwards. This condition can lead to various cardiovascular problems and is commonly associated with atherosclerosis. It is important to identify and address atheromas to prevent further complications in the cardiovascular system.
3.
Headquarters radio you back
immediately: "Put out alert to all units: watch this zone around the
clock", because if a clot breaks free and reaches the brain it will cause
a:
Correct Answer
D. Stroke
Explanation
If a clot breaks free and reaches the brain, it can cause a stroke. A stroke occurs when the blood supply to the brain is interrupted or reduced, leading to the death of brain cells. This can result in various symptoms such as sudden weakness or numbness in the face, arm, or leg, difficulty speaking or understanding speech, and loss of coordination. Therefore, it is important for all units to be on alert and watch the specified zone to prevent any potential stroke cases.
4.
You buzz a call to your buddies
and head on your way. In the distance you can see a bunch of fuzzy shapes
hanging around the corner of a capillary in a suspicious way. Your pulse races
- what if they're dangerous . . .
Correct Answer
C. Pathogens?
Explanation
The correct answer is "pathogens." In the given scenario, the person sees fuzzy shapes hanging around the corner of a capillary in a suspicious way, which raises concerns about their safety. Pathogens are microorganisms that can cause disease, so it is reasonable for the person to be worried about their presence. Erythrocytes are red blood cells, stem cells are undifferentiated cells, and gametes are reproductive cells, none of which would typically be associated with a suspicious situation.
5.
As you get closer you notice that
two of them seem to be getting up close and personal - a disgraceful display in
a public blood vessel. Worse still, they seem to getting ready to transfer
genetic material. You
Correct Answer
A. Smash their pili with a blow of your fist
Explanation
Pili are hair-like structures found on the surface of some bacteria that are involved in the transfer of genetic material between cells. By smashing their pili with a blow of your fist, you are disrupting their ability to transfer genetic material, which is considered a necessary action to prevent the disgraceful display and maintain public decorum.
6.
>LOOK
There are plasmids lying here. In fact, the place is a mess.
>GET PLASMIDS
You put the plasmids in your pack - they may come in useful later.
There are still some dodgy looking procaryotes hanging around. You muscle up to
one and prepare your membrane for
Correct Answer
D. Invagination
Explanation
The correct answer is "invagination". In the given scenario, the protagonist encounters dodgy-looking procaryotes and prepares their membrane for something. "Invagination" refers to the process of folding or pushing inwards, often used in biology to describe the folding of a cell membrane to create a pocket. This term makes sense in the context of preparing the membrane for interaction with the procaryotes.
7.
The bacterium squirms as you give
it the lysozyme treatment. Not so tough after all, dude.
You head on your way.
You're feeling a bit wobbly after all that street action - you need a hit of
sugar. Checking out the local plasma concentration, you're disappointed to find
only disaccharides. Maybe you can make do with some lactose - you suck on a few
molecules, but it's no good, the glucose you need is firmly bonded to a
Correct Answer
A. Galactose unit
Explanation
The correct answer is "galactose unit" because lactose is a disaccharide composed of glucose and galactose units. Since the glucose unit is firmly bonded to the galactose unit in lactose, sucking on lactose molecules will not provide the needed glucose.
8.
>INVENTORY
Lysozyme
Antigen receptors
DNA helicase
Gene-O-Meter(TM)
Plasmids
48,000 Lactose molecules
No wonder your pack is so heavy!
>DITCH LACTOSE
I don't understand ditch.
>DROP LACTOSE
You drop 48,000 lactose molecules.
If only you'd had something to hydrolyse their bonds . . . but what kind of
bonds were they?
Correct Answer
B. Glycosidic
Explanation
The correct answer is "glycosidic". The passage mentions that the 48,000 lactose molecules need to have their bonds hydrolyzed. The type of bonds in lactose are glycosidic bonds, so the correct answer is glycosidic.
9.
>SEARCH AMY LASE
. . . . searching database. . . .
No Match for Amy Lase.
She musta left town. No dice with the lactose.
You slump onto an epithelial cell.
C'mon, Jones. You can't stall now. Don't be such a Charlie Bringdown. Amy was
sweet but there's other enzymes out there with a curvy active site.
Yeah, but Amy never got inhibited. Remember, she had such a great
Correct Answer
D. Tertiary structure
Explanation
The passage mentions enzymes and their characteristics, suggesting that the question is related to enzymes. The passage also mentions Amy, who never got inhibited, implying that her characteristic is being referred to in the question. The term "tertiary structure" refers to the three-dimensional arrangement of a protein molecule, which is crucial for its function. Enzymes rely on their tertiary structure to perform their catalytic functions effectively. Therefore, the correct answer is "tertiary structure."
10.
Next thing you know, a waft of
plasma blows a squillion glucose molecules your way. You suddenly feel like a
million bucks again, and your mitochondria get all tingly in their
Correct Answer
A. Cristae
Explanation
Cristae are the folded inner membranes in mitochondria where cellular respiration takes place. They provide a large surface area for the electron transport chain and ATP synthesis. In the given context, the mention of mitochondria getting "tingly" suggests that the glucose molecules are being used for energy production through cellular respiration, which occurs in the cristae of mitochondria.
11.
But hold up, what's the deal here? A bunch of cheeky red blood cells
are giggling about you behind their haemoglobins. And your belt's way too tight
- you've got really fat! All that lack of ATP has played Old Harry with your
osmotic potential and you're about to burst! You quickly
Correct Answer
D. Pump sodium ions out of you
Explanation
When cells lack ATP, it affects their osmotic potential, causing them to swell and potentially burst. To prevent this, the cells need to regulate their ion balance. Pumping sodium ions out of the cell helps to restore the balance by reducing the concentration of sodium inside the cell. This movement of ions helps to maintain the cell's osmotic balance and prevent it from bursting.
12.
You take a breather and check out
one of the bits of broken plasmid from your pack, looking for clues. Luckily
you have some DNA helicase and your Gene-O-Meter(TM) and you can unzip the
double helix. Yup, this thing replicated semi-conservatively alright - you
mentally thank
Correct Answer
C. Meselson and Stahl
Explanation
Meselson and Stahl conducted an experiment in 1958 to prove that DNA replication occurs through a semi-conservative mechanism. They used heavy and light isotopes of nitrogen to label the DNA and then observed the distribution of the isotopes in subsequent generations of DNA. Their experiment provided strong evidence for the semi-conservative replication model, which states that each newly synthesized DNA molecule consists of one old strand and one newly synthesized strand.
13.
Your Gene-O-Meter(TM) bleeps. And
not a good bleep either. The red light on the top flashes, too. Uh-oh. This is
a code 413. The screen reads: *413 Severe Antibiotic Resistance Gene CBA
identified at Locus 782/14. Suggest immediate action*.
This ain't good. You'll need to call headquarters, all units, backup, T Cells,
Memory Cells and everyone else remotely immunological to combat these bugs
before they cause some bad craziness. Safety in numbers, so the best place to
be right now is in a
Correct Answer
A. LympH node
Explanation
The correct answer is a lymph node. The passage mentions calling for backup from T Cells, Memory Cells, and other immunological units to combat the bugs. Lymph nodes are an important part of the immune system and contain immune cells that help fight infections and pathogens. Being in a lymph node would provide the best chance for coordinating a response to the severe antibiotic resistance gene identified.
14.
You kick off across the capillary
and power into a gap between two epithelial cells, squeezing yourself through
with the help of some lubrication from some
Correct Answer
B. Interstitial fluid
Explanation
The interstitial fluid is the fluid that surrounds and fills the spaces between cells in the body. In this scenario, the interstitial fluid is mentioned as the lubrication that helps the person squeeze through the gap between two epithelial cells. Therefore, the interstitial fluid is the correct answer.
15.
At the lymph node (somewhere in
an armpit, ew!) things are busy. Leucocytes and phagocytes are crowding round
demanding information, and you toss them some antigens you tucked into your
belt when you offed the microbes. But there's a rumour going around . . . about
something worse, something no-one's sure about, news just in from the far
outposts of the salivary glands, or maybe the taste buds. At that very moment
your radio crackles and you hear just one phrase: "Vibrio C . . . Vibrio C
. . ." repeated faintly, over and over. If you had any blood, instead of
being a part of it, it would be running cold right now. It can mean only one
thing: there's an infection of
Correct Answer
D. Cholera
Explanation
The correct answer is cholera. The passage describes a situation where the person is in a lymph node and there is a rumor about something worse, which is confirmed when they hear the phrase "Vibrio C" repeatedly. This suggests that there is an infection of Vibrio cholerae, the bacterium that causes cholera.
16.
You feverishly (geddit?) try to
recall what you know about procaryotes, and about Cholera in particular . . .
damage host cells check, produce toxins check, Cholera's toxin does what . . .
Correct Answer
A. Causes cells to lose ions into the gut lumen
Explanation
Cholera's toxin causes cells to lose ions into the gut lumen. This is a characteristic of Cholera infection, where the toxin produced by the bacteria causes cells in the gut to release ions, leading to an imbalance in electrolytes and water absorption. This results in severe diarrhea and dehydration, which are common symptoms of Cholera.
17.
You power out of the lymph node,
sending other leucocytes reeling as you shoulder them aside. Squeezing into a
vein, you're shot back through the heart and after a quick but
impossible-to-avoid circuit of the lungs, you're out through the aorta once
more and heading for the intestinal capillaries. Once you're in a villus, you
squeeze through the epithelium and find yourself in a forest of
Correct Answer
D. Microvilli
Explanation
The correct answer is "microvilli" because the passage describes a journey through the body, specifically mentioning squeezing through the epithelium and finding oneself in a forest of something. Microvilli are tiny, finger-like projections found on the surface of epithelial cells in the intestines that increase the surface area for absorption of nutrients. They can be described as a "forest" due to their dense arrangement.
18.
>LOOK
You're surrounded by mucus and you struggle out of the microvillus tangle. It
looks like you're only just in time - away down the gut you can hear a low,
threatening chant and you can see dark shapes approaching.
Harsh voices rumble: "Here come the boys that'll give yer cholera,
flagellae and toxins all ready ter swallow yer." Or words to that effect.
You step out into the lumen and hold up a pseudopod.
"Not so fast, procaryote scum - where d'you think you're going?"
But you're ignored - and at that moment a gaggle of harmless (or even helpful)
E. coli pass by, obscuring your view. When you can see again, the intruders
seem to have gone - but then you notice discarded flagellae on the mucus
surface, which itself is writhing as they burrow beneath it.
You plunge to the attack, grappling in the darkness to find their cell walls,
hoping to feel some
Correct Answer
A. Peptidoglycan
Explanation
The correct answer is peptidoglycan. In the given passage, the protagonist is in a hostile environment surrounded by harmful bacteria. They notice discarded flagellae on the mucus surface, indicating the presence of bacteria. The protagonist is trying to locate the cell walls of these bacteria to fight against them. Peptidoglycan is a major component of bacterial cell walls, providing structural support and protection. Therefore, the correct answer is peptidoglycan.
19.
>LOOK
Darkness and mucus. A confused tangle of microvilli and microbes. The first few
toxin molecules targeting epithelial cells.
Your sense systems are in disorder and you feel out of your depth. But then you
get your first feel of a slime capsule and your invaginating membrane sucks in
the nastiness that is Vibrio cholerae. Over and over again your lysosomes claim
their prey, and bacterial antigen proteins are studded like trophies over your
external membrane.
Now you need to clone yourself to deal with any other outbreaks, and you
quickly replicate your DNA in readiness for
Correct Answer
C. Mitosis
Explanation
The passage describes the process of a cell engulfing Vibrio cholerae, a bacterium that causes cholera. The lysosomes of the cell destroy the bacteria, and the bacterial antigen proteins are displayed on the cell's membrane. The cell then needs to replicate itself to deal with any other outbreaks. The process of cell replication described in the passage aligns with mitosis, which involves the replication of DNA and division of the cell into two identical daughter cells. Therefore, the correct answer is mitosis.
20.
>LOOK
There's one last Cholera bug trying to make a getaway - as it speeds away from
you it sneers over its shoulder, "So long sucker, you won't catch me now,
and then it'll be Death by Osmosis, for your host body and then for you!"
Gritting your microtubules, you give a last desperate leap after the thug and
grab him by an antigen. He struggles furiously as he's torn apart by your top
grade lysozyme.
"It's Death by Osmosis alright," you chuckle to yourself. "Death
by Osmosis Jones!" Who needs a scriptwriter, you think to yourself,
looking around for someone to sell the movie rights to.
*CONGRATULATIONS*
**GAME OVER**
***YOU WIN***
Play again? (Y/N)
>QUIT
Now please complete this survey with the following question: have you enjoyed this adventure experience?
Correct Answer
A. It was awesome
Explanation
The given correct answer suggests that the person enjoyed the adventure experience. They found it awesome and entertaining.