Otterbein/Grant CRNA Diuretics Review
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Questions and Answers
- 1.
Both thiazide and loop diuretics mechanism of action are based upon inhibiting the reabsorption of Na+ and Cl- ions.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Thiazide and loop diuretics are both types of diuretic medications that work by inhibiting the reabsorption of sodium (Na+) and chloride (Cl-) ions in the kidneys. This leads to increased excretion of these ions in the urine, which in turn promotes water excretion and reduces fluid volume in the body. Therefore, the statement that both thiazide and loop diuretics mechanism of action are based upon inhibiting the reabsorption of Na+ and Cl- ions is true.Rate this question:
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- 2.
Osmotic diuretics work by _________ osmolarity, preventing water reabsorption, causing a loss of water, Na+, Cl-, and HCO3.
- A.
Increasing
- B.
Decreasing
Correct Answer
A. IncreasingExplanation
Osmotic diuretics work by increasing osmolarity. This means that they increase the concentration of solutes in the filtrate, which prevents water reabsorption in the kidneys. As a result, more water remains in the urine, leading to increased urine output. Additionally, the increased osmolarity also prevents the reabsorption of sodium (Na+), chloride (Cl-), and bicarbonate (HCO3-) ions, further contributing to the loss of water and electrolytes.Rate this question:
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- 3.
K+ sparing diuretics inhibit Na+, Cl-, and HCO3 reabsorption and K+ secretion in the distal convoluted tubules.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
K+ sparing diuretics are a type of medication that work by inhibiting the reabsorption of sodium (Na+), chloride (Cl-), and bicarbonate (HCO3) in the distal convoluted tubules of the kidneys. By doing so, these diuretics prevent the excretion of potassium (K+), hence the term "K+ sparing." Therefore, the statement that K+ sparing diuretics inhibit Na+, Cl-, and HCO3 reabsorption and K+ secretion in the distal convoluted tubules is true.Rate this question:
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- 4.
_________ antagonists bind to cytoplasmic mineralocorticoid receptors on collecting ducts, inhibiting the reabsorption of Na+ and Cl-, preventing the secretion of K+.
Correct Answer
AldosteroneExplanation
Aldosterone antagonists are drugs that bind to cytoplasmic mineralocorticoid receptors on collecting ducts. By doing so, they inhibit the reabsorption of Na+ and Cl-, which leads to increased excretion of these ions. Additionally, they prevent the secretion of K+, further contributing to increased excretion of this ion. This mechanism of action helps to reduce fluid retention and lower blood pressure. Therefore, the given correct answer, Aldosterone, is the hormone that these antagonists target to produce their effects.Rate this question:
- 5.
Carbonic anhydrase inhibitors bind to carbonic anhydrase in the proximal tubules, retaining H+ ions while excreting HCO3+ ions. K+ is also excreted in exchange for Na+. HCO3 excretion causes alkaline urine, the body enters a metabolic acidosis.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Example - acetazolamideRate this question:
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- 6.
Renal dopamine-1 receptors mediate vasodilation, _________ RBF and GFR while inhibiting Na+ reabsorption.
- A.
Increasing
- B.
Decreasing
Correct Answer
A. IncreasingExplanation
Work at dopamine receptors throughout renal tubulesRate this question:
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Current Version
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Mar 20, 2024Quiz Edited by
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Apr 07, 2015Quiz Created by
Alainad3
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