Pg Blazer - Online Test Series 18 - Paediatrics

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Subject wise MCQ test - Paediatrics. For more online practice tests, go to PG Blazer Online Test Series.


Questions and Answers
  • 1. 

    All of the following are true of Beta thalassemia major, except:

    • A.

      Splenomegaly

    • B.

      Target cells on peripheral smear

    • C.

      Microcytic hypochromic anemia

    • D.

      Increased osmotic fragility

    Correct Answer
    D. Increased osmotic fragility
    Explanation
    Osmotic fragility is decreases in Thalassemia. Increased osmotic fragility is seen in hereditary spherocytosis.

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  • 2. 

    Which of the following does not establish a diagnosis of congenital CMV infection in a neonate?

    • A.

      Urine culture of CMV

    • B.

      IgG CMV antibodies in blood

    • C.

      Lntra nuclear inclusion bodies in hepatocytes

    • D.

      CMV viral DNA in blood by polymerase chain reaction

    Correct Answer
    B. IgG CMV antibodies in blood
    Explanation
    Maternal IgG antibodies can pass into fetal circulation. Hence it is not possible to establish a diagnosis of congenital CMV infection in a neonate just by demonstrating the presence of IgG antibodies.

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  • 3. 

    Which of the following haemoglobin (Hb) estimation will be diagnostically helpful in a case of beta thalassemia trait?

    • A.

      HbF

    • B.

      HbA1c

    • C.

      HbA2

    • D.

      HbH

    Correct Answer
    C. HbA2
    Explanation
    Normal hemoglobin is composed predominantly of HbA1 – which is composed of 2 alpha chains and 2 beta chains. In beta thalassemia trait, there is decrease in production of beta chains of hemoglobin. But since the defect is minor, they will not have any clinical features and the peripheral smear may be normal. But there will be a compensatory increase in HbA2 which is composed of 2 alpha chains and 2 delta chains. Normally HbA2 constitutes about 1.5 to 3.5% of total hemoglobin. But in beta thalassemia trait, this increases to about 3.6 to 8%.

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  • 4. 

    Which one of the following in the characteristic feature of juvenile myoclonic epilepsy?

    • A.

      Myoclonic seizures frequently occur in the morning

    • B.

      Complete remission is common

    • C.

      Response to anticonvulsants is poor

    • D.

      Associated absence seizures are present in majority of patients

    Correct Answer
    A. Myoclonic seizures frequently occur in the morning
    Explanation
    Juvenile myoclonic epilepsy – Clinical features, treatment

    It starts in early adolescence
    Bilateral myoclonic jerks are seen
    Mostly in the morning
    Precipitated by sleep deprivation
    The patient usually remains conscious during the episode
    Associated with absence seizures and generalised tonic clonic seizures
    Benign condition
    Complete remission is uncommon
    Positive family history may be present
    Responds well to anticonvulsants
    Drug of choice – Valproate

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  • 5. 

    A child is below the third percentile for height. His growth velocity is normal. But chronological age is more than skeletal age. The most likely diagnosis is:

    • A.

      Constitutional delay in growth

    • B.

      Genetic short stature

    • C.

      Primordial dwarfism

    • D.

      Hypopituitarism

    Correct Answer
    A. Constitutional delay in growth
    Explanation
    The growth velocity and height for age in early childhood will be lower than normal in case of constitutional growth delay. But the final height attained will be normal. The skeletal maturation will be lower than expected for age.

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  • 6. 

    A 15-year old female presented to the emergency department with history of recurrent epistaxis, hematuria and hematochezia. There was a history of profuse bleeding from the umbilicus stump at birth. Previous investigations revealed normal prothrombin time, activated partial thromboplastin time, thrombin time and fibrinogen levels. Her platelet counts as well as platelet function tests were normal but urea clot lysis test was positive. Which one of the following clotting factor is most likely to be deficient?

    • A.

      Factor X

    • B.

      Factor XI

    • C.

      Factor XII

    • D.

      Factor XIII

    Correct Answer
    D. Factor XIII
    Explanation
    Clinical features of Factor XIII deficiency :-
    History of prolonged bleeding from umbilical stump
    Delayed bleeding
    Recurrent abortions

    Diagnosis (Investigations) :-
    Prothrombin time and Activated partial thromboplastin time are normal
    --Factor XIII is needed for stabilization of fibrin clot
    --Intrinsic and extrinsic pathways are not affected
    Clot stability in 5M urea – qualitative test
    --Normal clot remains stable in 5M urea
    --But in cases of Factor XIII deficiency, the clot dissolves
    --But it becomes positive only in very severe deficiency
    Quantitative factor XIII assay – using photometry

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  • 7. 

    All of the following are features of prematurity in a neonate, except:

    • A.

      No creases on sole

    • B.

      Abundant lanugo

    • C.

      Thick ear cartilage

    • D.

      Empty scrotum

    Correct Answer
    C. Thick ear cartilage
    Explanation
    Features of prematurity in a neonate:
    Flat and soft pinna, cartilage not reaching upto periphery
    Lightly pigmented scrotum with undescended testes
    Absence of deep creases on sole
    Poorly formed breast bud
    Fuzzy hair
    Prominent labia minora and clitoris (Labia majora are separated)

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  • 8. 

    A normally developing 10 month old child should be able to do all of the following except:

    • A.

      Stand alone

    • B.

      Play peek a boo

    • C.

      Pick up a pellet with thumb and index finger

    • D.

      Build a tower of 3-4 cubes

    Correct Answer
    D. Build a tower of 3-4 cubes
    Explanation
    A normal child can make a tower of 3 cubes by 18 months of age.

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  • 9. 

    Which of the following is the principal mode of heat exchange in an infant incubator?

    • A.

      Radiation

    • B.

      Evaporation

    • C.

      Convection

    • D.

      Conduction

    Correct Answer
    C. Convection
    Explanation
    Convection is the principal mode of heat exchange in an infant incubator. Convection involves the transfer of heat through the movement of fluids or gases. In an incubator, warm air is circulated around the infant to maintain a constant temperature. This circulation of warm air helps to distribute heat evenly and maintain a stable environment for the baby. Therefore, convection is the most important mode of heat exchange in an infant incubator.

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  • 10. 

    The following are characteristic of autism except:

    • A.

      Onset after 6 years of age

    • B.

      Repetitive behavior

    • C.

      Delayed language development

    • D.

      Severe deficit in social interaction

    Correct Answer
    A. Onset after 6 years of age
    Explanation
    Features of autism usually appear before 3 years of age. (OP Ghai)

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  • Current Version
  • Mar 17, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Jun 28, 2011
    Quiz Created by
    Pgblazer
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