Sulfonamides Quiz Questions With Answers

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| By Pkanke11pk

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Questions: 10 | Attempts: 3,221 | Updated: Dec 28, 2023

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Sulfonamides Quiz Questions With Answers - Quiz

Do you know about sulfonamides? What are they used for? Check out these sulfonamides quiz questions with answers and enhance your knowledge about this functional group. Sulfonamides, also called sulfa or sulpha drugs, are a class of antibiotics that kills bacteria causing infections. Sulfa is widely used to treat streptococcal infections. In this quiz, we asked a few basic questions about sulfonamides. Do you think you can answer them all? Give it a try and see for yourself. We wish you all the very best!

Questions and Answers

1.

What is folic acid?
- A.
  
  Protein
- B.
  
  Vitamin
- C.
  
  Mineral
- D.
  
  Nucleotide
Correct Answer
B. Vitamin

Explanation
Folic acid is a vitamin. It is a B-vitamin, specifically known as vitamin B9. Folic acid plays a crucial role in various bodily functions, including the production of red blood cells and the synthesis and repair of DNA. Adequate folic acid intake is particularly important during pregnancy to prevent certain birth defects and support fetal development.

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1
2.

Sulfonamides inhibit
- A.
  
  DHFS
- B.
  
  DHFR
- C.
  
  DPS
- D.
  
  None
Correct Answer
C. DPS

Explanation
Sulfonamides act by inhibiting the bacterial enzyme dihydropteroate synthetase (DPS) in the folic acid pathway, disrupting bacterial nucleic acid synthesis. By substituting for PABA, they hinder its conversion to dihydrofolic acid. This action, on its own, is recognized as bacteriostatic.

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3.

Sulfamethoxazole + Trimethoprim is a combination of
- A.
  
  Co-trimazole
- B.
  
  Co- Trimoxazole
- C.
  
  Co- trimethoxazole
- D.
  
  None
Correct Answer
B. Co- Trimoxazole

Explanation
Co-trimoxazole, belonging to the sulfonamide class, combines trimethoprim and sulfamethoxazole. Its mechanism involves halting bacterial growth.

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3
1
4.

Who discovered Sulfonamide?
- A.
  
  Flamingo
- B.
  
  Brotzu
- C.
  
  G. Domegk
- D.
  
  Both A & B
Correct Answer
C. G. Domegk

Explanation
ANSWER=C.

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5.

Trimethoprim acts by inhibiting the
- A.
  
  Bacterial Cell wall
- B.
  
  Cell membrane
- C.
  
  DHFS
- D.
  
  DHFR
Correct Answer
D. DHFR

Explanation
Trimethoprim acts by inhibiting the DHFR (Dihydrofolate Reductase enzyme in bacteria. This enzyme is involved in the synthesis of tetrahydrofolic acid (THF), which is essential for the production of nucleic acids and amino acids in bacteria. By inhibiting DHFR, trimethoprim disrupts bacterial metabolism and growth, ultimately leading to the inhibition of bacterial reproduction and the treatment of bacterial infections.

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4
6.

Sulfonamides are structurally similar to
- A.
  
  Furosemide
- B.
  
  Acetazolamide
- C.
  
  Benzothiazide
- D.
  
  All
Correct Answer
A. Furosemide

Explanation
ANSWER=D

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7.

Which of the Sulfonamide is used topically?
- A.
  
  Sulphadoxime
- B.
  
  Dapsone
- C.
  
  Silver sulphadiazine
- D.
  
  Sulphanethoxazole
Correct Answer
C. Silver sulpHadiazine

Explanation
Silver sulfadiazine is a sulfonamide that is used topically. It is commonly used as a topical cream in the treatment of burn wounds and certain skin infections. The silver component of the compound has antimicrobial properties, and the sulfadiazine component helps prevent or treat bacterial infections in the affected areas.

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8.

Sulphadiazine is an example of
- A.
  
  Antibiotic
- B.
  
  Short-acting sulpha drug
- C.
  
  Intermediate
- D.
  
  None
Correct Answer
A. Antibiotic

Explanation
Sulfadiazine is an example of an antibiotic. It is a synthetic compound belonging to the class of drugs known as sulfonamides. Sulfadiazine is commonly used to treat various bacterial infections and is particularly effective against urinary tract infections, certain types of pneumonia, and other bacterial conditions. It works by inhibiting the growth of bacteria and is often used in combination with other antibiotics for more effective treatment.

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9.

Sulphonamide is structurally and chemically related to...
- A.
  
  GABA
- B.
  
  PABA
- C.
  
  Both
- D.
  
  None
Correct Answer
B. PABA

Explanation
Sulphonamide is structurally and chemically related to PABA (Para-aminobenzoic acid). PABA is a component of folic acid, which is essential for the synthesis of nucleic acids (DNA and RNA) in bacteria. Sulphonamides are antimicrobial agents that work by interfering with the bacterial synthesis of folic acid, leading to the inhibition of bacterial growth and the treatment of bacterial infections. GABA (Gamma-Aminobutyric Acid) is a neurotransmitter in the central nervous system and is not directly related to sulphonamides.

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10.

Following are the first Sulfonamide drug
- A.
  
  Sulphadiazine
- B.
  
  Sulphadoxine
- C.
  
  Sulphapyridine
- D.
  
  Sulphacetamide
Correct Answer
A. SulpHadiazine

Explanation
Ans. C

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Current Version
Dec 28, 2023

Quiz Edited by
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Apr 21, 2020

Quiz Created by
Pkanke11pk

Sulfonamides Quiz Questions With Answers

What is folic acid?

Sulfonamides inhibit

Sulfamethoxazole + Trimethoprim is a combination of

Who discovered Sulfonamide?

Trimethoprim acts by inhibiting the

Sulfonamides are structurally similar to

Which of the Sulfonamide is used topically?

Sulphadiazine is an example of

Sulphonamide is structurally and chemically related to...

Following are the first Sulfonamide drug