1.
Which of the blood vessel layers contains smooth muscle and elastic fibers?
Correct Answer
D. Tunica media
Explanation
Slide 5
2.
In systemic circulation, blood pressure ______ as distance from the left ventricle increases and is lowest in the _______
Correct Answer
C. Decreases, blood entering right atrium
Explanation
Slide 11-13. Blood pressure is highest in aorta and continuously decreases as it moves along systemic circulation.
3.
When comparing the arterioles to capillaries, blood pressure is smaller in the ______ and diameter is larger in the _______
Correct Answer
A. Capillaries, arterioles
Explanation
Slide 9 & 12. Pressure continuously decreases as we move further through systemic circulation. BV diameter is smallest in the capillaries.
4.
Which of the following are paracrine substances secreted by endothelial cells that dilate the BV (Select 3)
Correct Answer(s)
A. Prostacyclin
B. Endothelium derived relaxing factor (EDRF)
C. Nitric oxide
Explanation
Note Nitric oxide is a type of EDRF
5.
During systole, an artery wall expands with new blood, whereas during diastole, the artery wall elastically retracts to original position, propelling blood forward.
Correct Answer
A. True
Explanation
Slide 24 & 25. Note this is in the arteries (the pressure resevoir) because they contain lots of elastic fibers. This does not happen in all BV
6.
A person's resting heart rate is 130/80, their pulse pressure is ___ mm Hg. Their mean arterial pressure is ____.
Correct Answer
A. 50, 96.67
Explanation
Pulse pressure = Systolic - Diastolic = 130 - 80 = 50......................... MAP = DP + 1/3(Pulse pressure) = 80 + (1/3)*50 = 96.67
7.
Blood flow is faster in venules than in capillaries
Correct Answer
A. True
Explanation
Slide 37 & 38
8.
Resistance is inversely proportional to the viscosity of the blood.
Correct Answer
B. False
Explanation
Resistance is directly proportional to viscosity of the blood. If there is greater viscosity there is more resistance.
9.
The hematocrit ratio _______ (Select 3)
Correct Answer(s)
A. Is generally lower for a female than for a male
C. Is the % volume of blood that is Red blood cells
D. Would most likely increase in a person after moving to a higher altitude location
Explanation
Hematocrit ratio is the % of blood volume that is red blood cells. It is higher generally higher in males. It would increase after moving to a high altitude location because the atmosphere would have less oxygen, triggering an increase in red blood cell production and therefore a higher hematocrit ratio.
10.
If a blood vessel decreased in radius by 3 times, the resistance would ______ by a factor of _____ times
Correct Answer
B. Increase, 81
Explanation
Resistance is inversely proportional to the 4th power of radius. Slide 46 & 48
11.
The major source of resistance in systemic circulation is at the level of the ______
Correct Answer
B. Arterioles
Explanation
Arterioles are the small blood vessels that connect arteries to capillaries. They play a crucial role in regulating blood flow and blood pressure. Due to their small diameter, arterioles offer the greatest resistance to blood flow in the systemic circulation. This resistance is important for maintaining proper blood pressure and ensuring that blood is distributed appropriately to different organs and tissues. Therefore, the major source of resistance in systemic circulation is at the level of the arterioles.
12.
Which of the following when increased, would increase resistance? (Select all that apply)
Correct Answer(s)
A. BV length
B. Hematocrit ratio
D. Blood viscosity
Explanation
All of the above are directly proportional to resistance (an increase in them would result in an increase in resistance). BV radius is inversely proportional (if you increase BV radius, there is less resistance). Also an increased hematocrit ratio means that the blood is more viscous, therefore has more resistance.
13.
Total peripheral resistance is ______ the resistance of any individual artery.
Correct Answer
A. Less than
Explanation
Total peripheral resistance (TPR) is a parallel type of resistance. Organ resistance is in series (you have to add all the individual resistances together).
14.
Which of the following are extrinsic mechanisms of controlling blood supply to organs? (Select 2)
Correct Answer(s)
A. ADH
C. Sympathetic/Parasympathetic input
Explanation
Flow autoregulation and Active hyperemia are examples of local controls (along with reactive hyperemia and response to injury)
15.
If blood flow is abnormally high to the brain, a flow autoregulation mechanism would act to _____ the blood vessel diameter in order to _____ blood flow
Correct Answer
A. Decrease, decrease
Explanation
In the given scenario, if blood flow to the brain is abnormally high, a flow autoregulation mechanism would act to decrease the blood vessel diameter in order to decrease blood flow. This mechanism helps to maintain a stable blood flow to the brain by adjusting the diameter of the blood vessels. By decreasing the diameter, the flow of blood is reduced, preventing excessive blood flow to the brain.
16.
Epinephrine can cause both vasoconstriction and vasodilation on arteriolar smooth muscle
Correct Answer
A. True
Explanation
However alpha receptors (vasoconstriction) outnumber beta receptors (dilation) so constriction is usually seen. ****skeletal muscles contain more beta receptors and so dilation is seen there*****
17.
Which of the following hormones decrease blood pressure?
Correct Answer
A. ANP
Explanation
ANP, or atrial natriuretic peptide, is a hormone that is released by the heart in response to high blood pressure. It acts to decrease blood pressure by promoting the excretion of sodium and water in the kidneys, leading to increased urine production. This helps to reduce the volume of blood in the bloodstream, ultimately lowering blood pressure.
18.
Blood flow to coronary vessels occurs _____
Correct Answer
A. Mainly during Diastole
Explanation
Because the coronary vessels are compressed during systole, flow occurs mainly during diastole.
19.
Arteriolar control of the heart vessels is mainly controlled by (Select 2)
Correct Answer(s)
A. Adenosine
C. Flow autoregulation
Explanation
Locally controlled by metabolic factors (adenosine) and flow autoregulation. Sympathetic input has little effect on coronary arterioles. Slide 94
20.
Which of the following organs have their arterioles controlled by sympathetic input (Select 2)
Correct Answer(s)
A. Skin
D. Skeletal muscles
Explanation
Brain and heart are controlled mainly by local metabolic controls.
21.
At the venous end of a capillary bed, the net filtration pressure is directed _____________
Correct Answer
A. Inwards towards the capillary (Negative net filtration)
Explanation
The arteriole end is positive (~ 10 mm Hg) and the venule end is negative (~ -7 mm Hg)
22.
In a capillary, ionized and polar molecules will diffuse through the capillary wall by
Correct Answer
B. By passing through intercellular clefts
Explanation
Slide 107 & 114
23.
Which of the following is true regarding the veins/venous system (Select 2)
Correct Answer(s)
A. They are more compliant than arteries
B. About 60% of blood volume is in the systemic veins
Explanation
Veins are more compliant than arteries because they have thinner walls and larger lumens, allowing them to stretch and accommodate changes in blood volume. This compliance helps to maintain blood pressure and prevent damage to the blood vessels. About 60% of the blood volume is in the systemic veins, which act as a reservoir for blood and can be quickly mobilized to maintain blood flow to vital organs.
24.
When the diaphragm contracts, (Select 2)
Correct Answer(s)
A. Pressure in the abdominal veins increases
D. Venous return is enhanced
Explanation
Slide 130-132
25.
Elephantiasis is caused by a malfunction mainly in the _________
Correct Answer
D. LympHatic system
Explanation
Slide 134
26.
The largest drop in blood vessel pressure occurs at the level of _______
Correct Answer
A. Arterioles
Explanation
Arterioles are small blood vessels that connect arteries to capillaries. They play a crucial role in regulating blood flow and blood pressure. Due to their small size and high resistance, arterioles experience the largest drop in blood vessel pressure. This is because the arterioles are responsible for controlling the amount of blood that flows into the capillaries, where exchange of nutrients and waste products occurs. Therefore, the correct answer is arterioles.
27.
During muscle contraction, the increased oxygen consumption stimulates production/release of compounds locally that dilate the blood vessel and cause an increase in blood flow to the muscle. This is an example of _________.
Correct Answer
D. Active hyperemia
Explanation
This is active hyperemia because blood flow is increased in response to increased metabolic activity.