1.
When healing is complete, which process removes unnecessary clotting material to prevent blood vessel blockage?
Correct Answer
B. Fibrinolysis
Explanation
Fibrinolysis is the process that breaks down fibrin, a protein that forms clots during healing. If this process didn't happen, clots wouldn't dissolve, potentially blocking blood vessels. The other answer choices are related to blood cell production (hematopoiesis, leukopoiesis) or deficiencies (leukopenia, thrombocytopenia) and aren't directly involved in removing used clotting material.
2.
What blood disease is caused by a single amino acid change in the beta chain of a globin molecule, making red blood cells sickle-shaped and prone to blockage?
Correct Answer
D. Sickle-Cell Anemia
Explanation
Sickle-Cell Anemia is the correct answer because it is a blood disease where the hemoglobin becomes spiky and sharp due to a change in just one amino acid in the beta chain of a globin molecule. This causes the blood cells to become wrongly shaped, leading to easy rupture and blockage of blood vessels. This results in a lack of accurate oxygen flow to the body.
3.
Which of the following is NOT a type of anemia:
Correct Answer
D. Reticulo
Explanation
The answer is Reticulocyte. Anemia refers to a condition with fewer healthy red blood cells. While reticulocytes are young red blood cells, they're still part of the red blood cell production process, not a type of anemia itself. The other choices (hemorrhagic, hemolytic, aplastic, iron-deficiency) are all valid classifications of anemia caused by different factors.
4.
Which type of lymphocyte functions in the immune response by directly attacking virus-infected cells and tumor cells?
Correct Answer
B. T-cells
Explanation
T-cells are a type of lymphocyte that play a crucial role in the immune response. They are responsible for directly attacking and eliminating virus-infected cells and tumor cells. T-cells can recognize specific antigens on the surface of these abnormal cells and initiate an immune response to destroy them. This process is essential for the body's defense against infections and the development of cancer.
5.
Which type of lymphocyte differentiates into plasma cells that produce antibodies for the immune response?
Correct Answer
B. B cells
Explanation
B cells are a type of lymphocyte that gives rise to plasma cells. Plasma cells are responsible for producing antibodies, which are released into the blood. This immune response is crucial for fighting off infections and providing long-lasting immunity. B cells play a vital role in the adaptive immune system by recognizing foreign antigens and producing specific antibodies to target and neutralize them. Therefore, B cells are the correct answer in this context.
6.
Which of the following is NOT a function of macrophages?
Correct Answer
C. Provide a rough index of the rate at which RBCs are produced.
Explanation
Macrophages are immune cells that play a crucial role in the body's defense against viruses, certain intracellular bacterial parasites, and chronic infections. They activate lymphocytes to mount the immune response and are derived from monocytes. However, macrophages do not provide a rough index of the rate at which red blood cells (RBCs) are produced. This function is primarily carried out by other cells, such as erythropoietin-producing cells in the kidneys.
7.
Which of the following is Leukopoeisis?
Correct Answer
A. The production of WBCs stimulated by chemical messengers.
Explanation
Leukopoiesis refers to the process of producing white blood cells (WBCs) in the body. This production is stimulated by chemical messengers, such as cytokines and growth factors, which regulate the differentiation and proliferation of WBC precursors in the bone marrow. Therefore, the correct answer is "The production of WBCs stimulated by chemical messengers."
8.
What is Leukopenia?
Correct Answer
B. An abnormally low WBC count commonly induced by drugs.
Explanation
Leukopenia refers to an abnormally low white blood cell (WBC) count, which is commonly induced by drugs. This condition can occur as a side effect of certain medications, such as chemotherapy drugs or immunosuppressants. Leukopenia can weaken the immune system and make individuals more susceptible to infections. It is important to monitor WBC counts and adjust medication dosages accordingly to prevent complications associated with leukopenia.
9.
What are leukemias?
Correct Answer
C. A group of cancerous conditions involving WBCs.
Explanation
Leukemias are a group of cancers that primarily affect the blood and bone marrow, characterized by the excessive production of abnormal white blood cells (WBCs). These malignant WBCs can crowd out normal blood cells, leading to serious problems such as anemia, bleeding, and infections. Leukemia cells proliferate rapidly and do not function properly as part of the immune system. There are various types of leukemia, classified based on the speed of progression (acute or chronic) and the type of blood cell affected (lymphocytic or myelogenous). Treatment and prognosis vary depending on these classifications and other individual factors.
10.
What is a leukocyte?
Correct Answer
D. WBCs that protect the body from damage by bacteria, viruses, parasites, toxins, and tumor cells.
Explanation
A leukocyte, commonly known as a white blood cell (WBC), is a cellular component of the blood primarily responsible for the body's immune response. Leukocytes protect the body against a multitude of pathogens including bacteria, viruses, and parasites, as well as from toxins and tumor cells. They play a crucial role in defending the body by identifying and eliminating harmful invaders and damaged cells. Different types of leukocytes (such as neutrophils, lymphocytes, monocytes, eosinophils, and basophils) perform specific functions in both the innate and adaptive immune responses, orchestrating a coordinated defense against infections and diseases.
11.
Which type of leukemia is chronic and slow-moving due to the proliferation of later cell stages?
Correct Answer
A. Chronic Leukemia.
Explanation
Chronic leukemia is characterized by the slow progression of disease, primarily involving the proliferation of more mature, or later stages, of blood cells. Unlike acute leukemia, which rapidly progresses and involves immature blood cells, chronic leukemia typically shows a more gradual increase in well-differentiated cells. This type of leukemia allows for more accumulation of these cells because they do not die off as quickly as the immature cells seen in acute forms. Patients with chronic leukemia may not show symptoms for years and often manage better over time with appropriate treatment, emphasizing the importance of distinguishing it from other faster-progressing forms.
12.
What term, meaning "leaping across," refers to the ability of white blood cells (WBCs) to slip out of capillary blood vessels?
Correct Answer
E. Diapedesis
Explanation
Diapedesis is the process by which white blood cells (WBCs) move through the wall of blood vessels into the tissues surrounding them. This term comes from the Greek word meaning "to leap across," aptly describing how these cells pass through the endothelial cells of the vessel walls. This capability is crucial for the immune response, as it allows white blood cells to exit the bloodstream and enter the tissues where they are needed to combat infections, clear out debris, or respond to inflammation. Diapedesis is a key step in the immune system's ability to reach and address pathological conditions effectively.
13.
What is the bleeding disorder characterized by a deficiency in circulating platelets, causing spontaneous bleeding from small blood vessels throughout the body?
Correct Answer
D. Thrombocytopenia
Explanation
Thrombocytopenia is a condition where the blood has an abnormally low number of platelets. Platelets are crucial for blood clotting, helping to stop bleeding by clumping and forming plugs in blood vessel injuries. When platelet levels are too low, spontaneous bleeding can occur from small blood vessels, and patients may experience easy bruising, frequent nosebleeds, or excessive bleeding from minor cuts or injuries. This disorder can be caused by various factors, including autoimmune diseases, certain medications, or bone marrow disorders. Managing thrombocytopenia typically involves treating the underlying cause or administering therapies to increase platelet counts.
14.
Who is theoretically considered a universal donor?
Correct Answer
D. Has type O blood.
Explanation
A person with type O blood is theoretically considered a universal donor. This designation is due to the absence of A and B antigens on the red blood cells of individuals with type O blood, which greatly reduces the risk of immune reactions in the recipient. Moreover, if the donor's blood type is O negative, which lacks the Rh factor antigen as well, they can safely donate to any other blood type (A, B, AB, or O) with positive or negative Rh status. This compatibility makes type O negative blood extremely valuable in emergency situations where there is no time to test a recipient's blood type.
15.
What term refers to several different hereditary bleeding disorders that involve prolonged bleeding into tissues from even minor tissue trauma, which can be life-threatening?
Correct Answer
C. HemopHilia
Explanation
Hemophilia is a group of hereditary bleeding disorders characterized by an abnormality in the clotting factors that help blood clot. People with hemophilia have a deficiency in one of the clotting factors, making them susceptible to prolonged bleeding even from minor injuries. The condition can lead to serious bleeding episodes, especially into the joints and muscles, which can be painful and potentially life-threatening if not managed properly. Hemophilia primarily affects males, as it is usually passed down through the X chromosome. Effective treatments often involve regular injections of the deficient clotting factor to prevent or control bleeding episodes.
16.
What is the term for the percentage of a blood's individual formed elements in comparison to the blood as a whole?
Correct Answer
B. The hematocrit.
Explanation
The hematocrit refers to the percentage of blood volume that is occupied by red blood cells. It is a key indicator used in medical tests to assess an individual's blood composition. The hematocrit value is important for diagnosing various conditions; a high hematocrit might indicate dehydration or polycythemia, while a low hematocrit can be a sign of anemia, bleeding, or other medical issues. This measurement helps medical professionals understand how much of the blood consists of red blood cells, providing crucial information about the patient’s overall health and oxygen-carrying capacity.
17.
What is an embolism?
Correct Answer
B. An embolus that is trapped in a narrow blood vessel.
Explanation
An embolism occurs when an embolus—any traveling particle or debris in the bloodstream, such as a blood clot, fat globule, air bubble, or other foreign body—becomes lodged within a blood vessel, blocking the flow of blood. This blockage can occur in any part of the vascular system and is potentially dangerous because it can restrict the blood supply to vital organs or tissues. Depending on where the blockage occurs, it can lead to severe conditions such as pulmonary embolism (in the lungs), cerebral embolism (in the brain), or myocardial infarction (in the heart). The outcome and severity of an embolism depend on the size and location of the embolus as well as the blood vessel involved.
18.
What does a CBC, or complete blood count, include?
Correct Answer
E. All of the above.
Explanation
A Complete Blood Count (CBC) is a highly informative blood test frequently ordered during physical examinations and before hospital admissions to assess a patient's general health status. It includes several critical measurements: the count of various types of blood cells (red cells, white cells, and platelets), a hematocrit (which measures the proportion of blood volume that is occupied by red blood cells), and measurements of the hemoglobin content and the size of red blood cells. These components provide a comprehensive overview of a patient's health in relation to normal blood values, aiding in the diagnosis of conditions like anemia, infections, and many other diseases.
19.
What is mainly composed of a soft network of reticular connective tissue bordering extensive blood capillaries and produces different numbers of each blood type as needed in response to the body's needs and regulatory factors?
Correct Answer
D. Red Bone marrow
Explanation
Red bone marrow is a key component of the body's hematopoietic (blood-forming) system. It is primarily composed of a soft network of reticular connective tissue, which is densely packed with blood capillaries. This structure supports the marrow's critical function in the production of blood cells. Red bone marrow produces red blood cells, white blood cells, and platelets, adjusting the production rates of these cells according to the body's needs and various regulatory factors, such as erythropoietin for red blood cells when oxygen levels are low. It is a vital organ for maintaining adequate levels of these cells to support the body's oxygen transport, immune functions, and blood clotting capabilities.
20.
Which drug inhibits thromboxane A2 formation and has shown, in studies, that men taking low doses experienced a 50% reduction in heart attack incidences over several years?
Correct Answer
D. Aspirin
Explanation
Aspirin is a medication that works by inhibiting the formation of thromboxane A2, a molecule that plays a key role in platelet aggregation and vasoconstriction. By blocking this molecule, aspirin effectively reduces the clotting ability of the blood, which is why it is often used in low doses as a preventative measure against heart attacks. Studies have demonstrated that regular intake of low-dose aspirin can significantly reduce the risk of a heart attack by about 50% over several years, particularly in men. This preventive effect is due to aspirin's ability to prevent the formation of blood clots that can block arteries leading to the heart.
21.
What is the straw-colored, sticky fluid in the blood, composed of 90% water?
Correct Answer
B. Plasma
Explanation
Plasma is the liquid component of blood that is straw-colored and sticky, comprising about 90% water. It serves as the medium in which red blood cells (RBCs), white blood cells (WBCs), platelets, and various other components are suspended. Plasma plays a crucial role in transporting nutrients, hormones, and proteins to parts of the body where they are needed. It also carries waste products to the liver, kidneys, and lungs for excretion. Besides water, plasma contains salts, enzymes, antibodies, and other proteins, making it essential for maintaining blood pressure and providing critical proteins for blood clotting and immune responses.
22.
Which protein, responsible for making red blood cells (RBCs) red, binds easily with oxygen molecules and carries most of the oxygen transported in the blood?
Correct Answer
A. Hemoglobin
Explanation
Hemoglobin is the protein that gives red blood cells their characteristic red color. It has a high affinity for oxygen, enabling it to bind easily and efficiently with oxygen molecules. Hemoglobin is crucial for the transportation of oxygen from the lungs to the tissues of the body, where it is released to facilitate cellular metabolism. Each molecule of hemoglobin can carry four oxygen molecules, making it highly effective for oxygen transport. This protein's structure allows it to also assist in the transport of carbon dioxide, a waste product of metabolism, from the tissues back to the lungs for exhalation.
23.
What is the process of red blood cell (RBC) production called?
Correct Answer
C. Erythropoiesis
Explanation
Erythropoiesis is the specific process of red blood cell (RBC) production. This process takes place primarily in the bone marrow, where stem cells develop into mature red blood cells under the influence of the hormone erythropoietin, which is largely produced in the kidneys. Erythropoiesis is essential for maintaining adequate oxygen-carrying capacity in the blood, as red blood cells are responsible for transporting oxygen throughout the body. The process ensures a constant supply of red blood cells to replace those that are old or damaged, typically having a lifespan of about 120 days in the circulation.
24.
Which type of agranulocyte contains a "U" shaped nucleus and differentiates into macrophages that protect against viruses, certain intracellular bacterial parasites, and chronic infections?
Correct Answer
B. Monocyte
Explanation
Monocytes are a type of agranulocyte characterized by a "U" shaped nucleus. They are significant components of the immune system, particularly in the response to various infections. Once they migrate from the bloodstream into tissues, monocytes mature into macrophages. These macrophages are versatile cells that perform multiple functions: they engulf and destroy pathogens, remove dead cells, and stimulate other immune cells. Their ability to handle viral infections, some intracellular bacterial parasites, and maintain responses in chronic infections is crucial. This flexibility makes monocytes a key player in both acute and chronic immune responses, adapting to different challenges as needed.
25.
Which of the following are NOT types of granulocytes?
Correct Answer(s)
C. Monocyte
E. LympHocyte
Explanation
Granulocytes, a type of white blood cell, include neutrophils, eosinophils, and basophils. These cells are characterized by the presence of granules in their cytoplasm, which are visible under a microscope. Neutrophils are the most abundant and are crucial in fighting bacterial infections. Eosinophils play a key role in combating parasitic infections and are involved in allergic reactions. Basophils are involved in inflammatory responses and allergic reactions. Monocytes and lymphocytes, however, are not granulocytes. Monocytes are a type of agranulocyte that becomes macrophages and is crucial for phagocytosis. Lymphocytes are critical for immune responses, including the production of antibodies and other immune functions.