1.
The most common site of a thyroglossal cyst is the
Correct Answer
D. Midline close to the hyoid bone
Explanation
The thyroid gland forms from a diverticulum in the midline of the floor of the pharynx.
The thyroid migrates caudally and passes ventral to the hyoid bone. During this migration, the thyroid remains connected to the tongue by the thyroglossal duct. If a part of the thyroglossal duct persists, a cyst develops, usually near the hyoid bone.
2.
Taste sensation from the oral part (anterior two thirds) of the tongue is predominantly carried by the
Correct Answer
B. Chorda tympani branch of the facial nerve (CN VII)
Explanation
Taste sensation from the mucosa for the oral part of the tongue is carried by the chorda tympani branch of the facial nerve (CN VII). This part of the tongue forms from pharyngeal arch 1, so the trigeminal nerve (CN V) will carry sensory innervation from the mucosa.
3.
The intermaxillary segment forms via the fusion of the
Correct Answer
E. Medial nasal prominences
Explanation
The intermaxillary segment, which plays a critical role in the formation of the definitive adult palate, forms when the two medial nasal prominences fuse in the midline.
4.
The most common site of a pharyngeal fistula is the
Correct Answer
B. Anterior border of sternocleidomastoid muscle
Explanation
A pharyngeal fistula forms when pharyngeal pouch 2 and pharyngeal groove 2 persist. Therefore, these fistulas are found on the lateral aspect of the neck, usually along the anterior border of the sternocleidomastoid muscle.
5.
What is the most common congenital malformation of the head and neck region?
Correct Answer
D. Unilateral cleft lip
Explanation
Unilateral cleft lip is the most common congenital malformation of the head and neck. Cleft lip occurs when the maxillary prominences fail to fuse with the medial nasal prominences and when the underlying somitomeric mesoderm and neural crest fail to proliferate, resulting in a persistent labial groove. Cleft lip occurs in 1 of 900 births and may be unilateral or bilateral
6.
Which pharyngeal arch is associated with Treacher Collins syndrome?
Correct Answer
A. pHaryngeal arch 1
Explanation
First arch syndrome results from abnormal development of pharyngeal arch 1 due to a lack of migration of neural crest cells. Treacher Collins syndrome is associated with underdevelopment of the zygomatic bone, down-slanting palpebral fissures, and deformed lower eyelids and external ears.
7.
During surgery for removal of a thyroid tumor, a number of small masses of glandular tissue are noted just lateral to the thyroid gland. Metastasis from the thyroid tumor is suspected, but histologic analysis of a biopsy reveals parathyroid tissue and remnants of thymus.
How can this finding be explained?
Correct Answer
C. Ectopic glandular tissue is commonly found in this region
Explanation
The parathyroid and thymus migrate in a caudal and medial direction during development; therefore, ectopic glandular tissue may be found anywhere along the migratory path.
8.
BRS EMBRYO EAR
The cochlear duct contains the spiral organ of Corti and is derived from which of the following?
Correct Answer
E. Ectoderm
Explanation
The cochlear duct is derived from a thickening of the surface ectoderm called the otic placode.
9.
The middle ear cavity
Correct Answer
B. Develops from pHaryngeal pouch 1
Explanation
The middle ear cavity develops from pharyngeal pouch 1 as it evaginates to form the tubotympanic
recess.
10.
The otic vesicle
Correct Answer
B. Is found adjacent to the rhombencepHalon
Explanation
The otic vesicle arises from an invagination of the surface ectoderm called the otic placode.
The otic vesicle is found adjacent to the rhombencephalon.
11.
The auricle (pinna) of the external ear is innervated by which of the following nerves?
Correct Answer
A. CN V3
Explanation
The auricle (pinna) of the external ear is innervated by cranial nerves V3 (mandibular division),
VII, IX, and X; cervical nerves C2 and C3 also innervate the auricle.
12.
VThe stapedius muscle that moves the stapes ossicle is innervated by
Correct Answer
D. CN VII
Explanation
The stapes is innervated by CN VII.
13.
The utricular portion of the otic vesicle gives rise to the
Correct Answer
C. EndolympHatic sac
Explanation
The utricular region of the otic vesicle gives rise to the endolymphatic sac and duct, and
semicircular ducts.
14.
The saccular portion of the otic vesicle gives rise to the
Correct Answer
A. Organ of Corti
Explanation
The saccular region of the otic vesicle gives rise to the cochlear duct, which houses the spiral
organ of Corti.
15.
The tubotympanic recess gives rise to
Correct Answer
A. A conduit that interconnects the middle ear and the nasopHarynx
Explanation
The tubotympanic recess is derived from pharyngeal pouch 1. It gives rise to the tympanic
cavity and the auditory (eustachian) tube; the auditory tube interconnects the tympanic cavity
with the nasopharynx.
16.
Perilymph enters the subarachnoid space via the
Correct Answer
C. PerilympHatic duct
Explanation
The perilymph enters the subarachnoid space of the posterior cranial fossa via the cochlear
aqueduct, which contains the perilymphatic duct.
17.
Pharyngeal groove 1 gives rise to the
Correct Answer
B. External auditory meatus
Explanation
Pharyngeal groove 1 gives rise to the external auditory meatus.
18.
BRS EMBRYO EYE
The surface ectoderm gives rise to which of the following structures?
Correct Answer
C. Lens
Explanation
The lens forms from the lens placode that is induced by the optic cup.
19.
Failure of the choroid fissure to close results in
Correct Answer
D. Coloboma iridis
Explanation
Failure of the choroid (optic) fissure to close results in a cleft of the iris, a coloboma iridis. This defect may extend into the ciliary body, choroid, optic nerve, or retina. Congenital aphakia, absence of the lens, may result from defective development of the lens placode.
20.
The optic cup is an evagination of which of the following?
Correct Answer
B. DiencepHalon
Explanation
The optic cup and its derivatives, the retina and optic nerve, develop from the diencephalon.
21.
The epithelium of the ciliary body is derived from
Correct Answer
D. Neuroecloderm
Explanation
The ciliary body is derived from the anterior two layers of the optic cup (neuroectoderm), which form the epithelium and form an anterior extension of the choroid (mesoderm).
22.
Hyperoxygenation of premature infants may result in
Correct Answer
D. Retrolental fibroplasia
Explanation
Retrolental fibroplasia results from hyperoxygenation of premature infants. In premature infants, high oxygen concentration results in vaso-obliteration of the terminal arterioles, leading to hemorrhage and infarction of the retina. This phenomenon is peculiar to the incompletely vascularized peripheral retina
23.
The optic nerve is a tract of the diencephalon that is not completely myelinated until
Correct Answer
E. 3 months after birth
Explanation
The axons of the optic nerve are not completely myelinated until 3 months after birth. Myelinated axons are normally not found in the retina. The optic nerve is not a true peripheral nerve but a tract of the diencephalon; when severed, the optic nerve does not regenerate.
Myelination in the CNS is accomplished by oligodendrocytes; oligodendrocytes are not found in the retina.
24.
The hyaloid canal is found in the
Correct Answer
A. Vitreous body
Explanation
The hyaloid canal (Cloquet's canal) is found in the vitreous body. In early development, a hyaloid artery passes through the vitreous body to perfuse the developing lens; in the late fetal period, this artery obliterates to form the hyaloid canal.
25.
Aqueous humor is produced by the
Correct Answer
C. Ciliary processes
Explanation
Aqueous humor is produced by the ciliary processes of the ciliary body. It flows from the posterior chamber, through the pupil, into the anterior chamber, and finally to the canal of Schlemm, which empties into the extraocular veins.
26.
Aqueous humor enters the venous circulation via
Correct Answer
D. Canal of Schlemm
Explanation
Aqueous humor enters the venous circulation via the canal of Schlemm. Blockage of this canal results in increased intraocular pressure (glaucoma).
27.
In a detached retina, the site of detachment is found
Correct Answer
E. Between the pigment epithelial layer and the layer of outer segments of rods and cones
Explanation
The site of retinal detachment is between the pigment epithelial layer and the layer of outer segments M rods and cones; this corresponds to the intraretinal space between the inner and outer layers of the optic cup. Retinal detachment occurs when fluid from the vitreous compartment passes through a retinal hole and separates the pigment epithelial layer from the layer of outer segments of rods and cones.