AHS 307 Dermatologic Drugs

Topical skin anesthetics work by inhibiting the transmission of nerve signals from sensory nerves, resulting in a reduction of pain and itching sensations. This is achieved by blocking the sodium channels in the nerve cells, preventing the generation and conduction of nerve impulses. As a result, the brain does not receive pain signals, leading to temporary numbness and relief from discomfort. Therefore, the statement is true.

Also used to treat moist dermatitis (hot spots), pyoderma, and other moist skin lesions that may be contaminated with bacteria.

atopic dermatitis is caused by allergies and is treated by antihistimines, allergen avoidance, steroids, fatty acid supplement, allergen specific immunothreapy (vaccine), bathing, or cyclosporine.

Hapten is a small allergenic protein. Some animals are more allergic than others.

Topical corticosteroids should NOT be put on lacerated skin because it will delay the healing process. Also, they may cause cushing's disease depending on how long term and how often they are used.

Also known as Koppertox

Other topical antifungals will do just as well, but these are mainly used for ringworm in veterinary practice

Other medications are used to get rid of the fleas. Cyclosporine can also be used to treat atopic dermatitis.

Lichenification is an exaggerated thickening of the skin combined with hyperpigmentation, resulting in a texture that resembles elephant skin. This condition is often caused by chronic irritation or scratching of the skin, leading to an increase in the production of skin cells and melanin. The thickened and darkened skin may appear rough, leathery, and have a distinct texture similar to the skin of an elephant.

Ketoconazole, itraconazole, and fluconazole are all antifungal medications that can be used orally to treat lichenification in dogs. Lichenification is a skin condition characterized by thickened, rough, and itchy patches. These medications work by inhibiting the growth of fungi, which can contribute to the development of lichenification. By reducing the fungal infection, these medications can help alleviate the symptoms and promote healing of the affected skin in dogs.

Seborrhea Sicca is dry, flakey skin; Seborrhea Oleosa is oily, flakey skin.

Keratolytics cause softening and swelling of the cells at the surface of the skin, so that the outer layer of the skin peels off or can peel more easily.

Miconazole and clotrimazole are both antifungal medications that can be used topically to treat lichenification in dogs. Lichenification is a condition characterized by thickened and hardened skin, often caused by chronic itching and scratching. These medications work by inhibiting the growth of fungi, which can contribute to skin irritation and inflammation. By reducing fungal overgrowth, miconazole and clotrimazole can help alleviate symptoms of lichenification and promote healing of the skin. Ketoconazole, itraconazole, and fluconazole are also antifungal medications, but they may not be as commonly used or as effective for treating lichenification in dogs.

Bacitracin/Polymixin are broad spectrum, and toxic if given orally or injected.
Gentamicin/Neomycin: broad spectrum, can be irritating when used alone.
Muciprocin: narrow spectrum; very effective against staph.
Nitrofurazone: narrow spectrum.

Local anesthetics are poorly absorbed from intact skin, but can be absorbed more easily through damaged skin