The Hematopoietic And Lymphoid Systems: Quiz!

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Quizzes Created: 22 | Total Attempts: 14,743
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  • 1/27 Questions

    Anemias of diminished erythropoiesis can be caused by bone marrow failure or replacement by tumor or inflammatory cells.

    • True
    • False
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About This Quiz

Different blood cells in the human body form through the hematopoietic process, which starts when an embryo is formed. Cells play a major role in the human body, especially the white blood cells, which fight infections throughout the body and are transported by the lymphatic system. Test your understanding of the Hematopoietic and lymphoid system by taking this test.

The Hematopoietic And Lymphoid Systems: Quiz! - Quiz

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  • 2. 

    Both folate deficiency and Vitamin B12 deficiency are examples of macrocytic anemias.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Both folate deficiency and Vitamin B12 deficiency can lead to macrocytic anemia, which is characterized by the presence of larger than normal red blood cells. This condition occurs when there is a disruption in the production of red blood cells, leading to fewer and larger cells being produced. Folate and Vitamin B12 are both essential for the production of red blood cells, and a deficiency in either nutrient can result in macrocytic anemia. Therefore, the statement is true.

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  • 3. 

    Which of the following is NOT a component of a CBC? A. WBC B. Platelets C. Glucose content D. Hemoglobin E. Indicies of RBC

    • A

    • B

    • C

    • D

    • E

    Correct Answer
    A. C
    Explanation
    Glucose content is not a component of a complete blood count (CBC). A CBC typically includes the measurement of white blood cells (WBC), platelets, hemoglobin, and indices of red blood cells. Glucose content is not directly related to the composition of blood and is typically measured separately in a blood glucose test.

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  • 4. 

    Acute leukemia is a malignancy of the hematopoietic progenitor cells, cells lose their ability to mature and differentiate, proliferate in an uncontrolled manner and replace normal bone marrow.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Acute leukemia is indeed a malignancy of the hematopoietic progenitor cells. In this condition, these cells lose their ability to mature and differentiate as they normally would. Instead, they proliferate in an uncontrolled manner and replace the normal bone marrow. This leads to an overproduction of immature white blood cells, which can be seen in the blood and bone marrow of individuals with acute leukemia. Therefore, the statement "Acute leukemia is a malignancy of the hematopoietic progenitor cells, cells lose their ability to mature and differentiate, proliferate in an uncontrolled manner and replace normal bone marrow" is true.

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  • 5. 

    The signs and symptoms of Acute myelogenous leukemia closely resemble the signs and symptoms of Acute lymphocytic leukemia.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    Both exhibit fatigue and bleeding

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  • 6. 

    Which of the following are causes of anemia? A. Diminished erythropoiesis B. Hemplysis C. Hemorrhage

    • All of the above

    • None of the above

    • A and B only

    • A and C only

    • B and C only

    Correct Answer
    A. All of the above
    Explanation
    All of the above are causes of anemia. Diminished erythropoiesis refers to a decrease in the production of red blood cells, which can lead to anemia. Hemolysis refers to the destruction of red blood cells, which can also result in anemia. Hemorrhage, or excessive bleeding, can cause a significant loss of red blood cells and lead to anemia as well. Therefore, all three options listed (A, B, and C) are valid causes of anemia.

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  • 7. 

    Which of the following is FALSE regarding folate deficiency? A. Caused by a poor diet B. Associated with pregnancy and alcohol abuse C. Common clinical symptoms include symmetric numbness, tingling, and burning in the hands or feet D. Macrocytic anemia

    • A

    • B

    • C

    • D

    • A and B only

    Correct Answer
    A. C
    Explanation
    Option C: Refers to Vitamin B12 deficiency - pernicious anemia

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  • 8. 

    Which of the following statements is false regarding malaria? A. It is endemic in Asia and Africa B. Red cells are destroyed and the patient suffers from chills and fever C. Malarial parasite is released approximately every 48 hours. D. HbA is protective against malaria

    • A

    • B

    • C

    • D

    Correct Answer
    A. D
    Explanation
    HbA is not protective against malaria. Malaria is caused by the Plasmodium parasite, which infects and destroys red blood cells. This leads to symptoms such as chills and fever. Malaria is endemic in Asia and Africa, and the malarial parasite is released approximately every 48 hours as part of its life cycle. However, HbA, which is the normal adult hemoglobin, does not provide any protection against malaria.

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  • 9. 

    Which of the following is NOT a characteristic of hemolytic anemia? A. Iron retention B. Increased rate of cell destruction C. Low reticulocyte count

    • A

    • B

    • C

    • A and B only

    • B and C only

    Correct Answer
    A. C
    Explanation
    A high reticulocyte count indicates that the anemia is not due to a production issue. Low reticulocytosis points to a possible defect in the bone marrow.

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  • 10. 

    Which of the lab findings correspond to Acute lymphocytic leukemia (ALL)? A. WBC > 100,000 and Platelets < 100,00 B. WBC >200,000 C. WBC >100,000

    • A

    • B

    • C

    Correct Answer
    A. A
    Explanation
    The lab findings that correspond to Acute Lymphocytic Leukemia (ALL) are a white blood cell count (WBC) greater than 100,000 and platelets less than 100,000. This combination of elevated WBC and low platelet count is commonly seen in ALL, which is a type of cancer that affects the white blood cells. The high WBC count is due to the overproduction of immature lymphocytes, while the low platelet count is a result of the bone marrow being crowded with cancerous cells, leading to a decrease in platelet production.

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  • 11. 

    Which of the following statements is FALSE? A. Von Willebrand disease is a defect in platelet function and depressed factor VIII level. B. Pleural diseases of the liver cause hemorrhagic diatheses. C. Vit. K is essential for the synthesis of prothrombin and clotting factors Vii, IX, X D. Factor VIII deficiency is treated with an infusion of Factor VIII (prepared from human plasma)

    • A

    • B

    • C

    • D

    Correct Answer
    A. B
    Explanation
    Pleural diseases of the liver do not cause hemorrhagic diatheses.

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  • 12. 

    Which of the following statements regarding thalassemia is TRUE? A. Indices of a patient may look like iron deficiency anemia B. There are two forms intravascular and extravascular C. Normocytic and normochromic

    • A

    • B

    • C

    • A and B only

    • B and C only

    Correct Answer
    A. A
    Explanation
    Thalassemia = is microcytic and hypochromic due to the precipitation of Hb; has two forms major and minor

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  • 13. 

    Which of the following statements is TRUE? A. Cells of individuals with hereditary spherocytosis are spherical instead of the biconcave disc B. Sickling of RBC occurs in individuals with sickle cell anemia when blood flow slows. C. Treatment for sickle cell anemia only includes pain management.

    • A

    • B

    • C

    • A and B only

    • B and C only

    Correct Answer
    A. A and B only
    Explanation
    Treatment for sickle cell anemia includes: oxygen, IV fluids, antibiotics, and pain management

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  • 14. 

    Which of the following statements pretain to Intravascular hemolytic anemias? A. It is more common than extravascular hemolytic anemia B. It takes place in the spleen or liver C. May be caused due to mechanical trauma, biochemical/physical agents  

    • A

    • B

    • C

    • A and B only

    • All of the above

    Correct Answer
    A. C
    Explanation
    Intravascular hemolytic anemias are characterized by the destruction of red blood cells within the blood vessels. The correct answer, option C, states that intravascular hemolytic anemias may be caused due to mechanical trauma, biochemical/physical agents. This means that factors such as physical injury or exposure to certain chemicals or substances can lead to the destruction of red blood cells within the blood vessels. Options A and B are incorrect because they do not pertain specifically to intravascular hemolytic anemias.

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  • 15. 

    Which statement concerning iron deficiency anemia is FALSE? A. Microcytic/hypochromic anemia B. Affects 10% of the population in developed countries C. May be caused by chronic slow blood loss from peptic ulcers, colon cancer, menses D. There is an excess of substances for hematopoiesis that are then sequestered in the liver.

    • A

    • B

    • C

    • D

    • A,B,C only

    Correct Answer
    A. D
    Explanation
    Additional facts about anemias of diminished erythropoiesis - clinical symptoms include weakness, listlessness, pallor, and pica.

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  • 16. 

    Which of the following is NOT a place where you would encounter slow blood flow? A. Areas of inflammation and infection B. Spleen C. Liver D. Bone Marrow

    • All of the above

    • None of the above

    • Two of the above

    • One of the above

    Correct Answer
    A. One of the above
    Explanation
    Sickling occurs with slow blood flow: areas of inflammation, infection and dehydration. Blood flow is slow in the spleen and bone marrow.

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  • 17. 

    Which of the following is a FALSE statement regarding acute hemorrhage? A. Hemodilution occurs which reveal the extent of the blood loss B. Leads to anemia of underproduction C. Due to ulceration and bleeding disorders D. Normocytic and normochromic

    • A

    • B

    • C

    • D

    • All of the above are true

    Correct Answer
    A. B
    Explanation
    Option B refers to Chronic Hemorrhage

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  • 18. 

    Which of the following pairs are causes for aplastic anemia? A. Certain viral infections and myelotoxic drugs B. Sulfonamides and Chloramphenicol C. Poor diet and inadequate dietary supply of substances from hematopoiesis

    • A only

    • B only

    • C only

    • A and B only

    • A and C only

    Correct Answer
    A. A and B only
    Explanation
    In aplastic anemia -multipotent myeloid stem cells are suppressed, marrow failure and pancytopenia. 50% of cases the cause is idiopathic

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  • 19. 

    Which of the following is NOT a cause for the malabsorption in pernicious anemia? A. Gastrectomy B. Diseases involving the distal ileum C. Resection of the ileum D. Due to the autoimmune reaction against intrinsic factor

    • All of the above

    • NONE of the above

    • B and C only

    • D only

    Correct Answer
    A. NONE of the above
    Explanation
    The correct answer is "NONE of the above." This means that all of the options listed (A, B, C, and D) are causes for malabsorption in pernicious anemia. Pernicious anemia is caused by a deficiency of intrinsic factor, which is necessary for the absorption of vitamin B12. Gastrectomy, diseases involving the distal ileum, and resection of the ileum can all lead to malabsorption of vitamin B12. Additionally, the autoimmune reaction against intrinsic factor can also cause malabsorption. Therefore, none of the options listed are excluded as causes for malabsorption in pernicious anemia.

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  • 20. 

    Which of the following is NOT a cause for bleeding disorders? A. Increased vessel fragility B. Deficiencies of platelets C. Derangements of clotting mechanisms (something is wrong with clotting)

    • A

    • B

    • C

    • A and B only

    • B and C only All of the above are causes for bleeding disorders.

    Correct Answer
    A. B and C only All of the above are causes for bleeding disorders.
    Explanation
    The correct answer is B and C only. Increased vessel fragility and derangements of clotting mechanisms are both causes for bleeding disorders. Deficiencies of platelets, on the other hand, are not a cause for bleeding disorders.

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  • 21. 

    Which of the following statements is TRUE? A. White cell disorders are caused by excessive proliferation having a neoplastic basis B. Hemostatic disorders lead to red cell deficiency C. Plasma cell dyscrasias originate from a cone of B cells that differentiate into neoplastic plasma cells

    • A

    • B

    • B

    • A and B

    • A and C

    • B and C

    Correct Answer
    A. A and C
    Explanation
    Option B = Hemostatic disorders result in hemorrhagic diathesis, e.g. bleeding orders

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  • 22. 

    Which of the following statements apply to Non-Hodgkin lymphomas instead of Hodgkin lymphoma A. Arise anywhere in the body where there is lymphatic tissue. B. Has a bimodal age distribution C. Stage IV is a disseminated disease with bone marrow or liver involvement

    • A

    • B

    • C

    • A and B only

    • All of thee above

    Correct Answer
    A. A
    Explanation
    Non-Hodgkin lymphomas arise anywhere in the body where there is lymphatic tissue, while Hodgkin lymphoma typically originates in the lymph nodes. Therefore, statement A applies to Non-Hodgkin lymphomas instead of Hodgkin lymphoma.

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  • 23. 

    Which of the following does NOT result in increased vessel fragility? A. Vit C deficiency B. Petechiae and ecchymosis in skin and mucus membranes C. Infectious and hypersensitivity vasculitides D. Vit B deficiency

    • A

    • B

    • C

    • D

    • A and D only

    • None of the above

    Correct Answer
    A. D
    Explanation
    Steroid use also increases vessel fragility

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  • 24. 

    Which of the following statements regarding Polycythemia is FALSE? A. It correlates with the increase in Hb concentration B. Blood is thickened leading to thrombosis C. Dilated, engorged, and tortuous retinal veins and arteries are visible ocular manifestations D. There are two types of polycythemia: primary and secondary

    • None of the above

    • Only one of the above is true

    • Two of the above is true

    • Three of the above is true

    • All of the above is true

    Correct Answer
    A. Three of the above is true
    Explanation
    There are two types of polycythemia: Relative and Absolute. Absolute polycythemia can be further divided into primary and secondary

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  • 25. 

    Which of the following is NOT characteristic of Sickle Cell anemia A. Autosplenectomy B. Disease is apparent in patients after 6 months of age C. Hematocrit: 30-40% range D. Pain can occur in many areas, with bone being the least common site of pain.

    • A

    • B

    • C

    • D

    • A and B

    • C and D

    Correct Answer
    A. C and D
    Explanation
    Hematocrit levels for sickle cell anemia is 18-30% Pain can occur in many areas but bone is MOST common

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  • 26. 

    Acute Lymphocytic Leukemia (ALL) has a ____ onset of very high lymphocyte count, very immature malignant cells. Chronic Lymphocytic Leukemia (CLL) has a _____ onset and is often discovered on routine blood exam.

    Correct Answer
    Rapid
    Slow
    Explanation
    Acute Lymphocytic Leukemia (ALL) is characterized by a rapid onset, with a sudden increase in lymphocyte count and the presence of very immature malignant cells. On the other hand, Chronic Lymphocytic Leukemia (CLL) has a slow onset and is often discovered during routine blood exams, as it progresses slowly over time.

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  • 27. 

    Chronic Myelogenous Leukemia (CML) has a diagnostic _______ chromosome. Treatment occurs by way of a _____ ( type of procedure).

    Correct Answer
    Philadelphia
    Bone marrow transplant
    Explanation
    Chronic Myelogenous Leukemia (CML) is diagnosed through the presence of the Philadelphia chromosome. This chromosome is a genetic abnormality that is found in the cancer cells of individuals with CML. The treatment for CML often involves a bone marrow transplant. This procedure replaces the diseased bone marrow with healthy bone marrow from a donor, which can help to eliminate the cancer cells and restore normal blood cell production.

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  • Jul 25, 2024
    Quiz Edited by
    ProProfs Editorial Team
  • Sep 17, 2011
    Quiz Created by
    Mchllmijares
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