Hmp Shunt - High Yield Topic Series

Approved & Edited by ProProfs Editorial Team

The editorial team at ProProfs Quizzes consists of a select group of subject experts, trivia writers, and quiz masters who have authored over 10,000 quizzes taken by more than 100 million users. This team includes our in-house seasoned quiz moderators and subject matter experts. Our editorial experts, spread across the world, are rigorously trained using our comprehensive guidelines to ensure that you receive the highest quality quizzes.

Learn about Our Editorial Process

| By Kar

Kar, Assistant Professor (Biochemistry)

Karthikeyan Pethusamy is an assistant professor in the Department of Biochemistry at the All India Institute of Medical Sciences in New Delhi

Quizzes Created: 33 | Total Attempts: 47,807

Questions: 6 | Attempts: 2,350 | Updated: Mar 22, 2023

Questions

Settings

Feedback

During the Quiz End of Quiz

Difficulty

Sequential Easy First Hard First

Play as

Quiz Flashcard

Create your own Quiz

All the Best ! Bookmark by pressing CTRL + D !

Questions and Answers

1.

Net Energy yield from pentose phosphate pathway is
- A.
  
  +2 ATP
- B.
  
  0 ATP
- C.
  
  +4 ATP
- D.
  
  -2 ATP
Correct Answer
B. 0 ATP

Explanation
The correct answer is 0 ATP. The pentose phosphate pathway is an alternative pathway to glycolysis for the breakdown of glucose. It primarily functions to generate NADPH and ribose-5-phosphate for nucleotide synthesis. While it does produce some ATP, the net energy yield from the pentose phosphate pathway is 0 ATP. This is because the ATP consumed in the initial steps of the pathway is later regenerated in subsequent steps, resulting in no net gain or loss of ATP.

Rate this question:

1
0
2.

HMP shunt is significant in cellular metabolism because it produces
- A.
  
  NADH
- B.
  
  NADPH
- C.
  
  Acetyl CoA
- D.
  
  ATP
Correct Answer
B. NADpH

Explanation
The HMP shunt is significant in cellular metabolism because it produces NADPH. NADPH is an important coenzyme involved in various metabolic reactions, including the synthesis of fatty acids and cholesterol, the regeneration of antioxidants like glutathione, and the production of reactive oxygen species (ROS) in immune cells. NADPH also plays a crucial role in maintaining the balance of cellular redox state and protecting cells from oxidative stress. Therefore, the production of NADPH through the HMP shunt is essential for cellular functions and survival.

Rate this question:

1
0
3.

NADPH is produced only by HMP shunt
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
cytoplasmic isocitrate dehydrogenase and malic enzyme can also produce NADPH.

Rate this question:

1
0
4.

Which is NOT true about the 2 phases of HMP shunt
- A.
  
  Oxidative Phase Generates NADPH
- B.
  
  Oxidative Phase is irreversible
- C.
  
  Nonoxidative Phase Generates Ribose Precursors
- D.
  
  NAD+ is the proton acceptor in oxidative phase
Correct Answer
D. NAD+ is the proton acceptor in oxidative pHase

Explanation
NADP+ is the proton acceptor

Rate this question:

2
0
5.

HMP shunt is active in all of the following EXCEPT
- A.
  
  RBC, liver & adipose tissue
- B.
  
  Adrenal cortex & Thyroid
- C.
  
  Testis & lactating mammary gland
- D.
  
  Skeletal muscle
Correct Answer
D. Skeletal muscle

Explanation
The HMP (hexose monophosphate) shunt is a metabolic pathway that occurs in various tissues and is responsible for the production of NADPH, which is important for cellular processes such as lipid synthesis and antioxidant defense. The HMP shunt is active in RBCs, liver, adipose tissue, adrenal cortex, thyroid, testis, and lactating mammary gland. However, it is not active in skeletal muscle. This is because skeletal muscle primarily relies on glycolysis for energy production and does not require the NADPH produced by the HMP shunt.

Rate this question:

1
0
6.

Transketolase reaction requires
- A.
  
  Mg2+
- B.
  
  Thiamin diphosphate
- C.
  
  Both
- D.
  
  None
Correct Answer
C. Both

Explanation
The correct answer is "Both". The transketolase reaction requires both Mg2+ and thiamin diphosphate. Mg2+ acts as a cofactor for the enzyme, helping to stabilize the reaction intermediates. Thiamin diphosphate, also known as vitamin B1, is a coenzyme that plays a crucial role in the transfer of two-carbon units during the reaction. Without either of these components, the transketolase reaction would not be able to proceed efficiently.

Rate this question:

2
0

Quiz Review Timeline +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

Current Version
Mar 22, 2023

Quiz Edited by
ProProfs Editorial Team
Jun 02, 2012

Quiz Created by
Kar

Hmp Shunt - High Yield Topic Series

Net Energy yield from pentose phosphate pathway is

HMP shunt is significant in cellular metabolism because it produces

NADPH is produced only by HMP shunt

Which is NOT true about the 2 phases of HMP shunt

HMP shunt is active in all of the following EXCEPT

Transketolase reaction requires