1.
1 in ______ children will develop cancer prior to reaching adulthood.
Explanation
The statement suggests that out of a certain number of children, one child will develop cancer before reaching adulthood. The number given in the answer, 300, represents the ratio or proportion of children who will develop cancer out of a larger group. Therefore, it can be understood that for every 300 children, one will develop cancer before reaching adulthood.
2.
A child newly diagnosed with Burkitt’s lymphoma is complaining of numbness and tingling in his hands and feet and has a decreasing urine output. The lab just reported the following: potassium 5.6 mEq/ml, calcium 7.9 mg/dl, and uric acid level of 9.3 mg/dl. Which of the following physician’s orders should the nurse anticipate receiving:
Correct Answer
A. Hyperhydration and urine alkalynization
Explanation
The child's symptoms, along with the abnormal lab values, suggest that the child is experiencing tumor lysis syndrome (TLS), which is a potential complication of Burkitt's lymphoma treatment. TLS occurs when large amounts of tumor cells are destroyed, releasing their contents into the bloodstream. This can lead to electrolyte imbalances, including high potassium levels, and high levels of uric acid. Hyperhydration and urine alkalynization are commonly used interventions to prevent and treat TLS. Hyperhydration helps to flush out the excess electrolytes and uric acid, while urine alkalynization helps to prevent the formation of uric acid crystals.
3.
A child with ALL CNS-1 is receiving triple intrathecal chemotherapy consisting of methotrexate, cytarabine, and hydrocortisone. The purpose of this is:
Correct Answer
E. Prevent CNS disease
Explanation
The purpose of administering triple intrathecal chemotherapy consisting of methotrexate, cytarabine, and hydrocortisone to a child with ALL CNS-1 is to prevent CNS disease. This treatment aims to target and eliminate any cancer cells that may have spread to the central nervous system, reducing the risk of disease progression or relapse in that area. By delivering the chemotherapy drugs directly into the cerebrospinal fluid, they can effectively reach the CNS and exert their cytotoxic effects on cancer cells, helping to prevent the development or recurrence of CNS disease.
4.
A child with cancer is admitted to the hospital with a fever of 39.0C and cough. His last round of history included high dose chemotherapy 8 days ago. Which of the following interventions should the nurse do first?
Correct Answer
D. Obtain blood cultures, begin IV hydration, and administer antibiotics
Explanation
Given the child's history of cancer and recent high dose chemotherapy, the nurse should prioritize obtaining blood cultures, beginning IV hydration, and administering antibiotics. This is because the child's symptoms of fever and cough could be indicative of a potential infection, which can be life-threatening for immunocompromised individuals. Blood cultures will help identify the specific pathogen causing the infection, while IV hydration and antibiotics will help treat the infection and provide supportive care. Obtaining a full history, obtaining a chest x-ray, and administering antipyretics can be important interventions, but they should be done after addressing the immediate concern of a potential infection.
5.
A nurse performs an assessment on a child with ALL in induction therapy. Which of the following findings are most significant?
Correct Answer
D. Decreased urine output and hyponatremia
Explanation
The most significant findings in a child with ALL in induction therapy would be decreased urine output and hyponatremia. Decreased urine output can indicate kidney dysfunction or dehydration, which are important to monitor in order to prevent complications. Hyponatremia, which is low sodium levels in the blood, can lead to neurological symptoms and can be life-threatening if not addressed promptly. These findings require immediate attention and intervention to ensure the child's safety and well-being.
6.
A school age child with cancer experienced severe nausea and vomiting when receiving chemotherapy the first time. Which of the following is the most appropriate nursing action to prevent or minimize these reactions with subsequent treatments?
Correct Answer
C. Administer an anti-emetic before the chemotherapy begins
Explanation
Administering an anti-emetic before the chemotherapy begins is the most appropriate nursing action to prevent or minimize nausea and vomiting in a child receiving chemotherapy. By giving the anti-emetic before the treatment, it can help prevent the onset of nausea and vomiting. This proactive approach is effective in managing these side effects and improving the child's overall comfort during subsequent treatments. Encouraging drinking large amounts of favorite fluids may not be enough to prevent or minimize these reactions, and administering an anti-emetic after the child has nausea may not be as effective as giving it before the chemotherapy. Encouraging the child to take nothing by mouth until nausea and vomiting subside may lead to dehydration and is not the best approach in this situation.
7.
Childhood cancer symptoms are often localized to the specific site of the cancer.
Correct Answer
B. False
Explanation
Childhood cancer symptoms are not always localized to the specific site of the cancer. In fact, symptoms of childhood cancer can vary widely depending on the type and stage of the cancer. Some common symptoms include unexplained weight loss, fatigue, fever, pain, and changes in the skin or eyes. These symptoms can occur throughout the body and may not be limited to the site of the cancer. Therefore, the statement that childhood cancer symptoms are often localized to the specific site of the cancer is false.
8.
Common symptoms of childhood leukemia include?
Correct Answer
A. Fatigue, Bruising, Bone Pain
Explanation
Common symptoms of childhood leukemia include fatigue, bruising, and bone pain. Fatigue is a result of the body's decreased ability to produce healthy blood cells. Bruising occurs due to a decrease in platelets, which are responsible for blood clotting. Bone pain can be caused by the overcrowding of abnormal cells in the bone marrow. These symptoms are often early indicators of leukemia and should be addressed by a healthcare professional for further evaluation and diagnosis.
9.
Most pediatric cancers arise from:
Correct Answer
C. Mesodermal or ectodermal tissue
Explanation
Pediatric cancers typically originate from either mesodermal or ectodermal tissue. Mesodermal tissue refers to the middle layer of cells in the developing embryo, which gives rise to various structures like muscles, bones, and connective tissues. Ectodermal tissue, on the other hand, refers to the outer layer of cells, which develops into the skin, nervous system, and other related structures. These tissues are more prone to developing cancerous cells in children, although the exact reasons for this are not fully understood by scientists.
10.
The classic cell seen under the microscope, which is diagnostic of Hodgkin’s disease is a
Correct Answer
A. Reed-Sternberg Cell
Explanation
The Reed-Sternberg cell is a classic cell seen under the microscope that is diagnostic of Hodgkin's disease. It is characterized by its large size, binucleate or multinucleate appearance, and owl's eye-like nucleus. This cell is not commonly found in other diseases, making it a key diagnostic feature for Hodgkin's disease. The other options mentioned in the question, such as small round blue cell, Reese-Ellsworth cell, and striated blue cell, are not associated with Hodgkin's disease.
11.
The main purpose of a clinical trial is to:
Correct Answer
D. Determine effectiveness of new treatments
Explanation
The main purpose of a clinical trial is to determine the effectiveness of new treatments. Clinical trials are conducted to evaluate the safety and efficacy of new drugs, therapies, or interventions in a controlled and scientific manner. These trials aim to gather evidence about the benefits and potential risks of the new treatment, and to determine whether it is more effective than existing treatments or a placebo. The goal is to provide reliable data that can inform medical decision-making and improve patient outcomes.
12.
The most common clinical manifestation(s) of brain tumors in children is which of the following?
Correct Answer
C. Headache and vomiting
Explanation
Brain tumors in children often present with headache and vomiting. These symptoms can occur due to increased pressure within the skull caused by the tumor. The tumor can obstruct the flow of cerebrospinal fluid, leading to increased intracranial pressure. Headache is a common symptom of increased pressure, while vomiting may occur due to the stimulation of the vomiting center in the brain. Other symptoms such as irritability and seizures can also occur, but headache and vomiting are the most common clinical manifestations of brain tumors in children.
13.
The most common site for osteogenic sarcoma is?
Correct Answer
B. Femur
Explanation
Osteogenic sarcoma, also known as osteosarcoma, is a type of bone cancer that commonly occurs in the long bones of the body, particularly the femur (thigh bone). This type of cancer often affects children and young adults, and the femur is the most frequently affected bone. The high growth rate of the bones during this age group makes them more susceptible to developing cancerous cells. Therefore, the femur being the most common site for osteogenic sarcoma is a well-established fact in medical literature.
14.
The nurse is preparing a teenager for possible alopecia from chemotherapy. Which of the following should be included?
Correct Answer
D. Explain to teenager that when hair regrows, it may have a slightly different color or texture.
Explanation
The correct answer is to explain to the teenager that when hair regrows, it may have a slightly different color or texture. This information is important for the teenager to know because it prepares them for the possibility of changes in their hair after chemotherapy. It helps manage their expectations and reduces any potential anxiety or distress they may experience when their hair starts to grow back.
15.
The overall cure rate for Acute Lymphocytic Leukemia is over 80%.
Correct Answer
A. True
Explanation
The statement is true because the overall cure rate for Acute Lymphocytic Leukemia is indeed over 80%. This means that more than 80% of patients diagnosed with this type of leukemia can be successfully treated and cured. This high cure rate is a result of advancements in medical treatments and therapies for leukemia, such as chemotherapy, radiation therapy, and stem cell transplantation. These treatments have significantly improved the prognosis for patients with Acute Lymphocytic Leukemia, leading to a higher chance of survival and cure.
16.
The treatment of brain tumors in children consist of which of the folllowing therapies? (Select all that apply.)
Correct Answer(s)
A. Surgery
C. Chemotherapy
E. Radiation
Explanation
The treatment of brain tumors in children typically involves a combination of surgery, chemotherapy, and radiation. Surgery is often the first step in removing the tumor, followed by chemotherapy to kill any remaining cancer cells and prevent recurrence. Radiation therapy may also be used to target and destroy cancer cells that cannot be surgically removed. Unrelated Donor Bone Marrow Transplant and Biotherapy are not commonly used in the treatment of brain tumors in children, so they are not included as therapies in this case.
17.
The upper and lower sections of the brain are separated by the:
Correct Answer
A. Tentorium
Explanation
The upper and lower sections of the brain are separated by the tentorium. The tentorium is a structure in the brain that acts as a partition between the cerebrum (upper section) and the cerebellum (lower section). It is a tough, crescent-shaped fold of the dura mater, which is the outermost layer of the meninges that surround and protect the brain. The tentorium helps to provide support and protection to the different regions of the brain, keeping them separate and preventing any interference between them.
18.
What is the name of the procedure shown below?
Correct Answer
B. Rotationplasty
Explanation
Rotationplasty is a surgical procedure where a section of the limb is removed and the remaining part is rotated and reattached to a different position, usually to serve as a new joint. This procedure is commonly used in cases of bone cancer or severe limb deformities. It allows for better functionality and mobility compared to traditional amputation. The other options mentioned, such as Harrington Rod or Arnold Turnaround, are not related to rotationplasty and are different procedures or medical devices.
19.
Which of the following immunizations should not be given to a child receiving chemotherapy for cancer?
Correct Answer
D. Measles, mumps, rubella
Explanation
Children receiving chemotherapy for cancer should not be given the measles, mumps, rubella (MMR) vaccine. This is because the MMR vaccine is a live attenuated vaccine, meaning it contains weakened forms of the viruses. In children with weakened immune systems, such as those undergoing chemotherapy, live vaccines can pose a risk of causing the disease they are intended to prevent. Therefore, it is important to avoid giving the MMR vaccine to these children to prevent any potential complications.
20.
Which of the following is most descriptive of the pathophysiology of leukemia?
Correct Answer
C. Unrestrictive proliferation of immature white blood cells occurs
Explanation
Leukemia is a type of cancer that affects the blood and bone marrow. The pathophysiology of leukemia involves the unrestrictive proliferation of immature white blood cells. This means that the body produces an excessive number of abnormal and immature white blood cells, which crowd out the healthy blood cells. This can lead to a decrease in the production of normal white blood cells, red blood cells, and platelets, causing symptoms such as increased blood viscosity and thrombocytopenia. The abnormal proliferation of white blood cells also disrupts the normal function of the immune system.