1.
The correct name for the acronym IACUC is
Correct Answer
A. Institutional Animal Care and Use Committee
Explanation
The correct answer is "Institutional Animal Care and Use Committee". This is the correct name for the acronym IACUC. The committee is responsible for overseeing and ensuring the ethical treatment and use of animals in research and teaching activities conducted at an institution. They review and approve protocols involving animal research, monitor animal welfare, and ensure compliance with regulations and guidelines.
2.
Typically at lest 50% of submitted proposals for grant money are funded
Correct Answer
B. False
Explanation
The statement contradicts the reality of grant funding. It claims that at least 50% of submitted proposals are funded, which is not true. In reality, the competition for grant money is usually fierce, and only a small percentage of proposals receive funding. Therefore, the correct answer is false.
3.
A typical grant provides money for a ___________ year period
Correct Answer
B. Three
Explanation
A typical grant provides money for a three-year period. This means that the grant recipient will receive funding for a duration of three years.
4.
The primary granting agency through which the United States conducts and supports biomedical research is ______________
Correct Answer
C. National Institutes of Health (NIH)
Explanation
The correct answer is National Institutes of Health (NIH). The NIH is the primary granting agency in the United States for biomedical research. It is responsible for conducting and supporting research in various areas of health and medicine. The NIH funds research projects, provides training and career development opportunities for scientists, and promotes the translation of research findings into medical advancements and public health interventions.
5.
Research institutions provide the Public Health Service with a signed agreement that outlines how the institution complies with all aspects of humane animal care as described in the pHS Policy , This agreement is called the _____________ Assurance
Correct Answer
B. Animal Welfare
Explanation
Research institutions provide the Public Health Service with a signed agreement that outlines how the institution complies with all aspects of humane animal care as described in the PHS Policy. This agreement is called the Animal Welfare Assurance.
6.
Only animals specifically named or included the Guide are used and cared for according to the established humane principles described in the Guide
Correct Answer
B. False
Explanation
The statement suggests that only animals specifically mentioned or included in the Guide are used and cared for according to humane principles. However, this is not true as the Guide is likely a set of guidelines or principles for the ethical treatment of animals, but it does not limit the application of these principles to only animals mentioned in the Guide. Animals not mentioned in the Guide can still be treated according to humane principles.
7.
The Guide for the Care and Use of Laboratory Animals ( the Guide ) Provides Basic information on animal use and is the standard used by the Association for Assessment and Accreditation of Laboratory animal care , International (AALAC International)
Correct Answer
A. True
Explanation
The statement is true because the Guide for the Care and Use of Laboratory Animals is indeed a document that provides basic information on animal use and is widely recognized as the standard by the Association for Assessment and Accreditation of Laboratory Animal Care, International (AALAC International). This guide is used by researchers, institutions, and regulatory bodies to ensure the ethical and responsible treatment of animals in laboratory settings.
8.
Specific state regulations that concern the sale and shipment of dogs exist because of distemper vaccination requirements
Correct Answer
B. False
Explanation
The statement suggests that specific state regulations exist because of distemper vaccination requirements. However, this is not true. While distemper vaccination requirements may be one factor considered in state regulations, there are likely other reasons for the existence of these regulations, such as ensuring the welfare of animals and protecting consumers from fraudulent or unethical practices.
9.
What agency is responsible for determining whether new medical devices ( like artificial joints and cardiac pacemakers ) are safe and effective before they are approved for sale in the united states
Correct Answer
C. Food and Drug Administration
Explanation
The Food and Drug Administration (FDA) is responsible for determining whether new medical devices, such as artificial joints and cardiac pacemakers, are safe and effective before they are approved for sale in the United States. The FDA is the regulatory agency that oversees the safety and efficacy of drugs, medical devices, food, cosmetics, and other products. They conduct thorough evaluations and assessments to ensure that these medical devices meet the necessary standards before they can be sold in the market.
10.
The USDA requires that common laboratory rodents be shipped with a health certificate
Correct Answer
B. False
Explanation
The statement is false because the USDA does not require common laboratory rodents to be shipped with a health certificate. While there may be guidelines and regulations in place for the transportation of laboratory animals, a health certificate is not specifically required by the USDA.
11.
States that allow the use of pound animals in research frequently have provisions which require that an impounded animal be held at a shelter for a minimum of five days to allow an owner the opportunity to reclaim a lost pet .
Correct Answer
A. True
Explanation
States that allow the use of pound animals in research often have provisions that require impounded animals to be held at a shelter for at least five days. This allows owners the opportunity to reclaim their lost pets.
12.
Standard operating Procedures ( SOPs ) should only be established for direct animal care procedures
Correct Answer
B. False
Explanation
Standard Operating Procedures (SOPs) should not only be established for direct animal care procedures. SOPs should also be established for various other aspects of animal care such as record-keeping, cleaning and sanitation, equipment maintenance, and staff training. These procedures ensure consistency, efficiency, and compliance with regulations in all aspects of animal care.
13.
Animals may be used for research after an animal use protocol is submitted to the IACUC
Correct Answer
B. False
Explanation
Animals may be used for research after an animal use protocol is submitted to the IACUC. This statement is false. The IACUC (Institutional Animal Care and Use Committee) is responsible for reviewing and approving animal use protocols to ensure that they meet ethical and legal standards. However, the submission of a protocol does not automatically grant permission to use animals for research. The IACUC must review and evaluate the protocol before making a decision.
14.
If animals are to euthanized at the end of the study , the method of euthanasia must be in accordance with the guidelines ( Panel on Euthanasia ) set up by the _________
Correct Answer
B. AVMA
Explanation
The correct answer is AVMA because the AVMA (American Veterinary Medical Association) is responsible for setting guidelines on euthanasia methods for animals. They provide guidance on the most humane and ethical ways to euthanize animals, ensuring that the process is carried out in a compassionate and respectful manner. The NIH (National Institutes of Health), PHS (Public Health Service), and USDA (United States Department of Agriculture) may have their own regulations and guidelines for animal research, but they are not specifically focused on euthanasia methods.
15.
Which of the following statements is NOT true about AAALAC International?
Correct Answer
D. It is a government - sponsored agency
Explanation
AAALAC International is not a government-sponsored agency. It is an independent, nonprofit organization that provides a mechanism for peer evaluation of animal care and use programs. It requires annual reports from its accredited facilities and conducts site visits every three years to ensure compliance with its standards.
16.
How long are assurance records related to grant applications to be maintained ?
Correct Answer
C. At least 3 years , following completion of the activity
Explanation
Assurance records related to grant applications are required to be maintained for at least 3 years following the completion of the activity. This means that after the experiment or project funded by the grant is finished, the assurance records must be retained for an additional 3 years. This is important for accountability and transparency purposes, as it allows for future reference and verification of the grant application process.
17.
What information do animal facility records provide ?
Correct Answer
A. They reflect whether environmental controls were properly maintained
Explanation
Animal facility records provide information on whether environmental controls were properly maintained. This information is crucial for ensuring the well-being and safety of the animals in the facility. It helps to monitor and maintain the appropriate temperature, humidity, lighting, and ventilation levels, which are essential for the health and welfare of the animals. Additionally, these records also help in complying with regulatory guidelines and standards. The other options mentioned in the question, such as the ability to repeat experiments under the same conditions and determining the success of an experiment, are not directly related to animal facility records.
18.
Why are perdiem rates different between institutions
Correct Answer
B. Some institutions include costs that others do not include
Explanation
The per diem rates are different between institutions because some institutions include costs that others do not include. This means that certain institutions may have additional expenses that they factor into their per diem rates, while others may not have those same costs. This difference in included costs leads to variations in the per diem rates among different institutions.
19.
How can you become more productive on the job and make better use of your time ?
Correct Answer
A. Time Management
Explanation
Time management is the correct answer because it refers to the practice of organizing and planning one's time effectively in order to be more productive and make better use of time. By setting goals, prioritizing tasks, and scheduling activities, individuals can allocate their time efficiently and avoid wasting time on unimportant or non-essential activities. This allows individuals to focus on important tasks, meet deadlines, and achieve better results in their work. Time management helps individuals to be more productive, reduce stress, and achieve a better work-life balance.
20.
When would you plan to work on a large assignment if you are a fast - paced morning person ?
Correct Answer
A. The first part of the day
Explanation
If someone is a fast-paced morning person, it means they are most productive and focused during the early hours of the day. Therefore, it would be logical for them to plan to work on a large assignment during the first part of the day when they have the most energy and concentration. This would allow them to make the most progress and complete the assignment efficiently.
21.
What should you do when a task is delegated to you?
Correct Answer
A. Make sure you completely understand the instructions
Explanation
When a task is delegated to you, it is important to make sure you completely understand the instructions. This ensures that you have a clear understanding of what needs to be done and how to do it. By fully understanding the instructions, you can avoid any confusion or mistakes that may arise from misinterpretation. This also allows you to ask any necessary questions or seek clarification if needed. Understanding the instructions is crucial for successfully completing the delegated task and meeting expectations.
22.
What should you do after you delegate a task to someone else?
Correct Answer
C. Follow up to be sure it has been completed
Explanation
After delegating a task to someone else, it is important to follow up to ensure that it has been completed. This is necessary to ensure that the task was understood correctly, to address any questions or concerns that may have arisen during the process, and to provide any necessary feedback or guidance. Simply assuming that the person knows what they are doing and leaving them alone may lead to misunderstandings or incomplete work. Checking the room log may provide some information, but it is still important to directly communicate and follow up with the person to ensure the task's completion.
23.
What additional knowledge is required to assist in hematology
Correct Answer
C. An understanding of blood cell morpHology
Explanation
To assist in hematology, having an understanding of blood cell morphology is crucial. This knowledge allows for the identification and interpretation of different types of blood cells, which is essential in diagnosing and monitoring various blood disorders and diseases. It enables the technician to recognize abnormalities in cell shape, size, and structure, which can provide valuable diagnostic information. Without this understanding, it would be challenging to accurately analyze blood samples and provide appropriate treatment recommendations.
24.
The gauge of the needle refers to the
Correct Answer
C. Diameter
Explanation
The gauge of the needle refers to its diameter. The diameter of the needle is an important factor in determining the size of the needle and its suitability for a specific injection. A smaller gauge needle has a smaller diameter, while a larger gauge needle has a larger diameter. The gauge of the needle affects the flow rate of the injected substance and the level of discomfort experienced by the patient during the injection. Therefore, understanding the gauge of the needle is crucial for healthcare professionals to ensure safe and effective injections.
25.
Which lists routes of injections from fastest absorption to slowest?
Correct Answer
A. IV,IP, IM, SC. IP
Explanation
The correct answer is IV, IP, IM, SC. IP. This is because intravenous (IV) injections have the fastest absorption rate as the medication is directly injected into the bloodstream. Intraperitoneal (IP) injections have a slightly slower absorption rate as the medication is injected into the peritoneal cavity. Intramuscular (IM) injections have a slower absorption rate as the medication is injected into the muscle tissue. Subcutaneous (SC) injections have an even slower absorption rate as the medication is injected into the fatty tissue layer beneath the skin. Finally, the second IP in the answer options is likely a typo or error.
26.
What helps to prevent cells lysis during blood collection?
Correct Answer
D. A large size needle
Explanation
A large size needle helps to prevent cell lysis during blood collection because it allows for a faster and smoother flow of blood, reducing the chances of cells being damaged or ruptured. A smaller needle may cause more resistance and turbulence, leading to cell lysis. Additionally, a larger needle can also help ensure that an adequate amount of blood is collected without the need for excessive force or multiple attempts, further minimizing the risk of cell damage.
27.
What quadrant is an IP injection given in ?
Correct Answer
A. Lower right
Explanation
An IP injection is given in the lower right quadrant. This means that the injection is administered in the lower right area of the body.
28.
Up to 0.5 mls of fluid can be injected into an intradermal site
Correct Answer
B. False
Explanation
The statement is false because the correct amount of fluid that can be injected into an intradermal site is up to 0.1 ml, not 0.5 ml.
29.
The most desirable site for an IM injection is _____________
Correct Answer
A. A large muscle mass
Explanation
The most desirable site for an IM injection is a large muscle mass because it allows for better absorption and distribution of the medication. Large muscle masses have a greater blood supply, which helps in the faster and more efficient delivery of the injected medication into the bloodstream. Additionally, injecting into a large muscle mass reduces the risk of hitting nerves or blood vessels, minimizing the chances of complications.
30.
what site can multiple blood samples be obtained from rodents in a 24 hour period
Correct Answer
B. SapHenous Vein
Explanation
The correct answer is the Saphenous Vein. The Saphenous Vein is a commonly used site for obtaining multiple blood samples from rodents in a 24-hour period. It is easily accessible and provides a sufficient amount of blood for analysis. Other sites such as the Tail Vein, Ear, and Heart may also be used for blood collection, but they may not be as suitable for multiple samples within a short period of time.
31.
Which is a key difference between IV injection and blood withdrawal?
Correct Answer
A. Pressure is maintained on the vein proximal to the injection site
Explanation
The key difference between IV injection and blood withdrawal is that pressure is maintained on the vein proximal to the injection site during IV injection, whereas pressure does not need to be applied to the site after blood withdrawal. This means that during IV injection, pressure is applied to prevent blood from flowing back into the vein, while during blood withdrawal, pressure is not necessary as the goal is to remove blood from the vein.
32.
In what type of procedure is cardiac puncture mostly used ?
Correct Answer
B. Non- survival
Explanation
Cardiac puncture is mostly used in non-survival procedures. This means that the procedure is performed on an animal that is not expected to survive. In non-survival procedures, the animal is euthanized or sacrificed after the procedure is completed. Cardiac puncture involves inserting a needle into the heart to collect blood or administer substances directly into the bloodstream. This procedure is commonly used for research purposes, such as collecting blood samples for analysis or administering drugs in animal studies.
33.
If blood samples are beign collected at frequent intervals , the guideline often used to insure the health of the animal is that the volume of blood equal to 1% of the animal's weight can be taken every two weeks
Correct Answer
A. True
Explanation
The guideline states that the volume of blood equal to 1% of the animal's weight can be taken every two weeks to ensure the health of the animal. This means that frequent blood samples can be collected without causing harm or stress to the animal. Therefore, the statement is true.
34.
What is the approximate blood volume of an animal ?
Correct Answer
A. 6% of body weight
Explanation
The approximate blood volume of an animal is typically around 6% of its body weight. This means that for every kilogram of body weight, the animal will have approximately 60 milliliters of blood. This is an important measurement as it helps in understanding the circulatory system and the amount of blood needed to supply oxygen and nutrients to the body's tissues.
35.
What is the term for placement of a liquid into the stomach by using a tube attached to a syringe?
Correct Answer
C. Gavage
Explanation
Gavage is the term used for the placement of a liquid into the stomach using a tube attached to a syringe. This method is commonly used in medical procedures to administer medication or nutrients directly into the stomach when oral intake is not possible. Esophageal dosing refers to the administration of medication into the esophagus, bolusing refers to the administration of a large amount of fluid quickly, and intubation refers to the insertion of a tube into a body cavity.
36.
How do you determine how far to insert a gavage needle ?
Correct Answer
D. Line up the ball at the level of the last rib
Explanation
To determine how far to insert a gavage needle, one should line up the ball at the level of the last rib. This means that the needle should be inserted until the ball reaches the level of the last rib. This method ensures that the needle is inserted to the correct depth and prevents it from being inserted too far or not far enough. By using the last rib as a reference point, the correct placement of the needle can be achieved consistently.
37.
How is a gag used in oral dosing of large animals ?
Correct Answer
B. Secure the animal's mouth around the gag and pass the tube through it
Explanation
The correct answer is to secure the animal's mouth around the gag and pass the tube through it. This method is used in oral dosing of large animals to ensure that the medication or substance being administered is properly delivered into the animal's digestive system. By securing the animal's mouth around the gag, it prevents the animal from biting or chewing on the tube, and passing the tube through the gag allows for easy and controlled administration of the dose.
38.
What is a unit of hereditary characteristics?
Correct Answer
C. Gene
Explanation
A gene is a unit of hereditary characteristics. Genes are segments of DNA that contain the instructions for building proteins, which are responsible for the traits and functions of living organisms. Genes are passed down from parents to offspring and determine various physical and behavioral traits. Chromosomes are structures that contain genes, but they are not the unit of hereditary characteristics themselves. Alleles are alternative forms of a gene, and DNA is the molecule that carries genetic information, but neither of them is the unit of hereditary characteristics.
39.
Which of the following represent dominant alleles?
Correct Answer
D. Capital letters
Explanation
Dominant alleles are the alleles that are expressed in the phenotype when present in either one or two copies. In this context, capital letters represent dominant alleles because they are typically used to denote dominant traits in genetics. Capital letters are commonly used to represent the dominant form of a gene, while lowercase letters are used for the recessive form. Therefore, capital letters are the correct answer as they represent dominant alleles.
40.
When does a recessive gene usually express?
Correct Answer
B. When 2 recessive alleles are present
Explanation
A recessive gene usually expresses when 2 recessive alleles are present. This means that both copies of the gene are recessive, and there are no dominant alleles present to mask the expression of the recessive trait. In this case, the recessive trait will be visible or expressed in the individual's phenotype.
41.
The observable or discernible characteristics of an animal are known as the ______________ ?
Correct Answer
D. pHenotype
Explanation
The observable or discernible characteristics of an animal are known as the phenotype. This includes physical traits such as color, size, and shape, as well as behavioral traits. The phenotype is influenced by the animal's genotype, which is its genetic makeup, but it can also be influenced by environmental factors. The taxonomic profile refers to the classification of an animal into a specific taxonomic group, such as a species or a genus. The phylum is a higher taxonomic rank that groups animals based on certain shared characteristics.
42.
Which part of the mouse model BALB/c StCrl p GF (F83) is the strain symbol ?
Correct Answer
D. BALB
Explanation
The strain symbol in the mouse model BALB/c StCrl p GF (F83) is BALB.
43.
What does " +" represent as a gene symbol ?
Correct Answer
B. The normal or wild type
Explanation
The gene symbol "+" represents the normal or wild type allele. This means that it is the most common or typical form of the gene found in a population. It is considered the standard or reference allele against which other alleles are compared.
44.
What is the difference between genotype and phenotype ?
Correct Answer
C. Genotype is what the genes are , pHenotype is what genes are expressed
Explanation
The correct answer explains that genotype refers to the genetic makeup or composition of an organism, while phenotype refers to the observable characteristics or traits that are expressed as a result of the genes. In other words, genotype represents the genes that an organism possesses, while phenotype represents how those genes are expressed and manifest in the organism's physical appearance or behavior.
45.
What color is a mouse with the genotype B/b
Correct Answer
A. Black
Explanation
The genotype B/b indicates that the mouse has one dominant allele (B) for black fur color and one recessive allele (b) for brown fur color. Since black is dominant over brown, the mouse will have black fur.
46.
What is the term used when more than one dominant allele affects a trait?
Correct Answer
B. Incomplete dominance
Explanation
Incomplete dominance is the correct answer because it refers to a situation where neither of the two alleles is completely dominant over the other, resulting in a blending or intermediate phenotype. In this case, both alleles contribute to the phenotype, leading to a unique expression of the trait that is different from the dominant-recessive pattern. Complex dominance, shared dominance, and split dominance are not valid terms used to describe this phenomenon.
47.
What is the name of a cell produced at fertilization by the union of sperm and egg?
Correct Answer
B. Zygote
Explanation
A zygote is the cell that is formed when a sperm fertilizes an egg during the process of fertilization. It is the earliest stage of development and contains the complete set of genetic material from both the sperm and the egg. The zygote will then undergo cell division and development to eventually form an embryo. Gametes are the reproductive cells (sperm and egg) that unite during fertilization, but the zygote is the specific cell that is formed as a result of this union. Fetus refers to the later stages of development in the womb, and oocyte is an immature egg cell.
48.
Ferrets, cats, and rabbits are the common laboratory species which are induced ovulators
Correct Answer
A. True
Explanation
Ferrets, cats, and rabbits are indeed common laboratory species that exhibit induced ovulation. This means that these animals release an egg from their ovaries in response to mating or other external stimuli. Unlike humans and some other animals, they do not have a regular menstrual cycle and only ovulate when stimulated. This characteristic makes them suitable for certain types of research studies in the laboratory setting.
49.
Of the four stages of estrus , which is defined as that where follicle development takes place?
Correct Answer
D. Proestrus
Explanation
Proestrus is the stage of estrus in which follicle development takes place. During this stage, the follicles in the ovaries start to grow and develop, preparing for ovulation. The hormone estrogen is also released during proestrus, which leads to the thickening of the uterine lining. This stage is characterized by behavioral changes, such as increased flirtation and receptivity to mating.
50.
For the purpose of artificial insemination, collection of sperm form small rodents is performed by extraction directly from the testes / epididymis following euthanasia
Correct Answer
A. True
Explanation
The statement is true because for artificial insemination, the collection of sperm from small rodents is indeed performed by extracting it directly from the testes or epididymis after the animal has been euthanized. This method ensures that the highest quality and most viable sperm is obtained for the insemination process.