NCLEX Pharmacology Quiz 30 Anti-infective Drugs And Topical Agents
All questions are shown, but the results will only be given after you’ve finished the quiz. You are given 1 minute per question, a total of 10 minutes in this quiz.
- 1.
Corinne is experiencing diarrhea after consuming her prescribed antibiotics for the whole week. This is because:
- A.
The drugs render food indigestible.
- B.
Gastric flora is disturbed.
- C.
Fluid is added into the intestine.
- D.
Normal intestinal bacteria are destroyed.
Correct Answer
D. Normal intestinal bacteria are destroyed.Explanation
The destruction of normal intestinal flora causes diarrhea. In choice A. a drug that rendered food indigestible could not be given because it would cause severe malnutrition. Choice B is incorrect because there is no gastric flora. Choice C is incorrect because there is no way to add fluid into the intestine.Rate this question:
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- 2.
When a client with chronic obstructive pulmonary disease is taking theophylline also receives ciprofloxacin (Cipro). which of the following interaction could occur?
- A.
Ciprotoxicity
- B.
Ineffectiveness of ciprofloxacin
- C.
Theophylline toxicity
- D.
Ineffective theophylline
Correct Answer
C. TheopHylline toxicityExplanation
Theophylline toxicity may occur because the action of theophylline is increased when given with Ciprofloxacin. There is no such thing as ciprotoxicity.Rate this question:
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- 3.
The client at highest risk for nephrotoxicity with aminoglycoside use is a:
- A.
Male with a creatinine of 1.7 and BUN of 52 on a 10-day regimen
- B.
Female with BUN of 12 and creatinine of 0.8
- C.
Female with past history of cystitis on 5 days of therapy
- D.
Male with history of kidney stones on 8 days of therapy
Correct Answer
A. Male with a creatinine of 1.7 and BUN of 52 on a 10-day regimenExplanation
Choice B is incorrect because a 24-year-old woman with a normal BUN and creatinine would not be at higher risk than others when given aminoglycosides. Choice C is incorrect because recurrent cystitis on limited-time therapy does not present a high risk for nephrotoxicity. The last choice is incorrect because a history of kidney stones on limited-time therapy does not present a high risk for nephrotoxicity.Rate this question:
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- 4.
When assessing clients for evidence of a penicillin allergy. which of the following symptoms may not be considered to be a true hypersensitivity reaction?
- A.
Wheezing
- B.
Nausea
- C.
Urticaria
- D.
Angioneurotic edema
Correct Answer
B. NauseaExplanation
GI disturbances such as nausea are usually caused by direct irritation or overgrowth of gram-positive bacteria or yeasts and are not indicative of a true penicillin allergy.Rate this question:
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- 5.
All of the following symptoms are evidence of a superinfection except:
- A.
White oral plaques
- B.
Creamy vaginal discharge
- C.
Skin rash
- D.
Darkened tongue
Correct Answer
C. Skin rashExplanation
Skin rashes are indicative of hypersensitivity reactions in clients on penicillin therapy.Rate this question:
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- 6.
Which of the following statements is true when educating clients about penicillin therapy?
- A.
The client must take the medication at evenly spaced intervals.
- B.
The client may save leftover medication for a future illness.
- C.
If signs of an allergic reaction. continue the medication and notify physician.
- D.
Clients taking oral contraceptives must be cautioned to use an alternate form of birth control while being treated with penicillin.
Correct Answer
D. Clients taking oral contraceptives must be cautioned to use an alternate form of birth control while being treated with penicillin.Explanation
Penicillin will reduce the effectiveness of birth control pills.Rate this question:
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- 7.
Antonietta is taking antituberculars. the most common adverse effect she may be experiencing is:
- A.
Red-orange discoloration of urine
- B.
Hypersensitivity
- C.
Hepatotoxicity
- D.
CHF
Correct Answer
C. HepatotoxicityExplanation
Hepatotoxicity is the most common side effect associated with antitubercular agents. Orange discoloration is a side effect of rifampin but not with antituberculars in general.Rate this question:
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- 8.
In treatment of tuberculosis. the therapeutic rationale for combination drug therapy is to:
- A.
Decrease cost and improve compliance.
- B.
Reduce the incidence of cumulative effects.
- C.
Increase blood dyscrasias.
- D.
Decrease emergence of drug-resistance strains.
Correct Answer
D. Decrease emergence of drug-resistance strains.Explanation
Combination therapy helps decrease the emergence of drug-resistant strains. Multiple drugs usually increase cost and reduce compliance. Multiple drugs increase cumulative effects. Blood dyscrasias would be an untoward effect not a desired effect.Rate this question:
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- 9.
Changes in visual acuity and color perception are associated with treatment by which of the following agents?
- A.
INH (isoniazid)
- B.
PZA (pyrazinamide)
- C.
ETH (ethambutol)
- D.
SM (streptomycin)
Correct Answer
C. ETH (ethambutol)Explanation
Ethambutol will cause changes in visual acuity and color perception. Remember “E” for ethambutol and eyes. Peripheral neuropathy is a side effect associated with INH. Gout is a side effect associated with pyrazinamide. Ototoxicity may occur with streptomycin.Rate this question:
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- 10.
Which of the following groups of antitubercular agents includes first-line agents?
- A.
INH. PZA. RIF
- B.
SM. PAS. INH
- C.
EMB. PAS. INH
- D.
INH. cycloserine. RIF
Correct Answer
A. INH. PZA. RIFExplanation
INH. PZA. and RIF are used as combination first-line agents.Rate this question:
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Aug 22, 2023Quiz Edited by
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Aug 10, 2017Quiz Created by
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