1.
Exposure of left subclavian artery by supraclavicular approach does not require cutting of :
Correct Answer
C. Scalenus medius
Explanation
Scalenus medius is located posterior to the subclavian artery. Hence there is no need to cut this to expose the subclavian artery.
2.
Facial Nerve stimulation during testing of nerve is indicated by contraction of which muscle
Correct Answer
D. Orbicularis oris
Explanation
Among the options given, only orbicularis oris is supplied by facial nerve.
3.
Most common site of ectopic pancreatic tissue is
Correct Answer
A. Stomach
Explanation
Common sites of ectopic pancreatic tissue - stomach, meckel's diverticulum.
4.
True about blood pressure measurement is all except
Correct Answer
B. Diastolic blood pressure is indicated by fourth Korotkoff sound
Explanation
Diastolic blood pressure is indicated by disappearance of Korotkoff sounds.
5.
Liver synthesizes all, except
Correct Answer
D. Immunoglobulin
Explanation
Immunoglobulins are synthesized by B lymphocytes.
6.
Dinitrophenol causes:
Correct Answer
C. Uncoupling of oxidation and pHospHorylation
Explanation
Dinitrophenol uncouples oxidation and phosphorylation in the respiratory chain. The hydrogen ions re enter the mitochondrial matrix without ATP synthesis. The energy is released as heat.
7.
Regarding synthesis of triacyl glycerol in adipose tissue, all of the following are true except:
Correct Answer
B. Enzyme Glycerol kinase plays an important role
Explanation
Glycerol kinase is not involved in the triglyceride synthesis in adipose tissue.
8.
Post transplant lymphoma occurs due to proliferation of which of the following cells
Correct Answer
B. B cell
Explanation
Post transplant lymphoma occurs due to the proliferation of B cells. After a transplant, the immune system is suppressed to prevent rejection of the transplanted organ. This suppression can lead to uncontrolled growth of B cells, resulting in post transplant lymphoma. B cells are responsible for producing antibodies and are an important part of the immune response. In the context of transplantation, the proliferation of B cells can lead to the development of lymphoma, a type of cancer that affects the lymphatic system.
9.
Acid phosphatase is specific to which of the following cells
Correct Answer
A. Monocyte
Explanation
Although all hematopoietic cells contain acid phosphatase, maximum levels are seen in macrophages.
10.
Most common cause of Traveller‘s diarrhoea :
Correct Answer
A. Enterotoxigenic E. coli
Explanation
Enterotoxigenic E. coli is the most common cause of traveller's diarrhoea.
11.
A elderly male presented with fever, chest pain and dry cough. Sputum was cultured on charcoal yeast medium, the organism identified will be
Correct Answer
C. Legionella
Explanation
The patient presented with history of pneumonia. Charcoal yeast medium is the special medium for legionella culture.
12.
Nevirapine belongs to the following group
Correct Answer
A. Non Nucleoside Reverse Transcriptase Inhibitor (NNRTI)
Explanation
Nevirapine and Efavirenz are Non Nucleoside Reverse Transcriptase Inhibitors (NNRTI)
13.
All are true about immunosuppressants except?
Correct Answer
C. MycopHenolate inhibit purine synthesis via GMP dehydrogenase
Explanation
Mycophenolate inhibit purine synthesis via IMP (Inosine monophosphate) dehydrogenase
14.
The following drug acts by hypomethylation
Correct Answer
C. Decitabine
Explanation
Decitabine acts by causing hypomethylation. It inhibits DNA methyl transferase.
15.
Drug causing hypercoagulability is:
Correct Answer
A. L asparginase
Explanation
L asparginase causes hypercoagulability by decreasing synthesis of Factor S / Factor C / Antithrombin III
16.
Methotrexate is used in high doses in:
Correct Answer
A. Osteosarcoma
Explanation
Methotrexate is used in high doses (with leucovorin rescue) for treatment of osteosarcoma, hematological malignancies and brain tumours.
17.
A person presents to the emergency with rigors and chills and a clinical picture resembling malaria. Which of the following poisoning is likely
Correct Answer
C. Zinc
Explanation
Zinc poisoning is likely in this scenario because the symptoms described (rigors and chills) resemble those seen in malaria, and zinc toxicity can cause similar symptoms. Mercury poisoning can cause neurological symptoms, red phosphorous poisoning can cause respiratory symptoms, and arsenic poisoning can cause gastrointestinal symptoms. Therefore, zinc is the most likely poisoning based on the given clinical picture.
18.
All of the following are true about cluster sampling except
Correct Answer
A. Samples are similar to those in Simple Random sampling
Explanation
Sampling is cluster sampling is different from that in simple random sampling.
19.
A data is arranged as satisfied, very satisfied, dissatisfied. This is a
Correct Answer
B. Ordinal data
Explanation
The given data is arranged in a specific order, indicating a hierarchy or ranking of satisfaction levels. This suggests that the data is ordinal, as it represents a qualitative variable with distinct categories that can be ranked or ordered.
20.
A study was conducted to test if use of herbal tea played any role in prevention of common cold. Data was collected on the number of people who developed cold and those who did not develop cold and this data was tabulated in relation to whether they consumed Herbal tea or not. The analytical test of choice to test this study is:
Correct Answer
C. Chi square test
Explanation
The test required is a non parametric test (to compare qualitative data). Chi square test a frequently used non parametric test.
21.
You have diagnosed a Patient clinically as having SLE and ordered 6 tests out of which 4 tests have come positive and 2 are negative. To determine the probability of SLE at this point, you need to know
Correct Answer
A. Prior probability of SLE, sensitivity and specificity of each test
Explanation
To determine the probability of SLE in this case, it is important to consider the prior probability of SLE, which is the likelihood of a patient having SLE before any test results are known. Additionally, the sensitivity and specificity of each test are crucial factors in determining the accuracy of the test results. Sensitivity refers to the ability of a test to correctly identify individuals with the condition, while specificity refers to the ability of a test to correctly identify individuals without the condition. These factors, along with the test results, help in calculating the probability of SLE in the patient.
22.
The following are components of Brown Sequard syndrome except :
Correct Answer
D. Contralateral posterior column involvement
Explanation
In brown sequard syndrome ( hemisection of spinal cord ), there is ipsilateral posterior colum involvement.
23.
Which of the following is the classical CSF finding seen in Tuberculous meningitis?
Correct Answer
A. Increased protein, decreased sugar, increased lympHocytes
Explanation
The classical CSF finding seen in Tuberculous meningitis is increased protein, decreased sugar, and increased lymphocytes. This is a characteristic pattern observed in the cerebrospinal fluid (CSF) of patients with Tuberculous meningitis. The increased protein level is due to the inflammatory response caused by the infection, while the decreased sugar level is a result of the bacteria consuming the glucose in the CSF. The increased lymphocytes indicate an immune response to the infection.
24.
All of the following organs may be involved in Leprosy except:
Correct Answer
A. Uterus
Explanation
Female genital tract is seldom involved in leprosy. Ovary is the most common site of leprosy in the female genital tract.
25.
Treatment of severe ulnar neuritis in borderline tuberculoid leprosy is:
Correct Answer
B. MDT + steroid
Explanation
The correct answer is MDT + steroid. Ulnar neuritis is a common complication in leprosy, especially in borderline tuberculoid leprosy. MDT (multi-drug therapy) is the standard treatment for leprosy, but in severe cases of ulnar neuritis, the addition of steroids is recommended. Steroids help reduce inflammation and alleviate symptoms such as pain, numbness, and weakness. Therefore, combining MDT with steroids is the most appropriate treatment option for severe ulnar neuritis in borderline tuberculoid leprosy.
26.
True regarding Couvade syndrome is?
Correct Answer
A. A male experiencing pregnancy symptoms
Explanation
Couvade syndrome (sympathetic pregnancy / phantom pregnancy) is a condition in which a man experiences some of the same symptoms and behavior of an expectant mother.
27.
Arsenic is used in treatment of
Correct Answer
A. Acute promyelocytic leukemia
Explanation
Arsenic is used in the treatment of Acute Promyelocytic Leukemia (APL). APL is a subtype of acute myeloid leukemia (AML) characterized by the presence of a specific genetic mutation. Arsenic trioxide, a form of arsenic, has been found to be effective in inducing remission in patients with APL by promoting the degradation of the abnormal protein produced by the genetic mutation. This treatment has shown good results in clinical trials and is now considered a standard therapy for APL.
28.
Plasmapheresis (plasma exchange therapy) is used in the treatment of
Correct Answer
C. Thrombotic thrombocytopenic purpura
Explanation
It can also be used for HUS, but is not as successful.
29.
Which of the following is not a complication of surgery for thoracic outlet syndrome.
Correct Answer
C. LympHocutaneous fistula
Explanation
A lymphocutaneous fistula is not a complication of surgery for thoracic outlet syndrome. A lymphocutaneous fistula is an abnormal connection between the lymphatic system and the skin, causing lymph to drain through the skin. Complications of surgery for thoracic outlet syndrome typically include pneumothorax (collapsed lung), brachial plexus injury (nerve damage in the shoulder and arm), and long thoracic nerve injury (nerve damage affecting the muscles that stabilize the shoulder blade).
30.
Stone which is resistant to lithotripsy
Correct Answer
C. Cystine stone
Explanation
Cystine stone is resistant to lithotripsy.
31.
True about solitary rectal ulcer syndrome is all/except
Correct Answer
C. Lamina propria infiltration with lympHocyte
Explanation
Histology of solitary rectal ulcer syndrome shows relative absence of inflammatory cells in the lamina propria.
32.
Fruit Juice which helps in preventing UTI
Correct Answer
A. Cranberry
Explanation
Cranberry juice is known for its ability to prevent urinary tract infections (UTIs). It contains compounds called proanthocyanidins, which help prevent bacteria from attaching to the urinary tract walls. This prevents the bacteria from causing an infection. Regular consumption of cranberry juice can help maintain a healthy urinary tract and reduce the risk of UTIs.
33.
Hypothyroidism in pregnancy is least likely to be associated with
Correct Answer
B. Polyhydramnios
Explanation
Hypothyroidism in pregnancy is least likely to be associated with polyhydramnios. Polyhydramnios refers to an excessive accumulation of amniotic fluid in the womb, which can be caused by various factors including fetal abnormalities, maternal diabetes, and certain infections. However, hypothyroidism is not typically known to be a direct cause of polyhydramnios. Instead, it is more commonly associated with complications such as recurrent abortions, PIH (pregnancy-induced hypertension), and preterm labor.
34.
Which of the following is the least likely physiological change in pregnancy
Correct Answer
D. Increase in peripHeral vascular resistance
Explanation
There is decrease in peripheral vascular resistance during pregnancy.
35.
Most common heart disease which is associated with maximum mortality during pregnancy
Correct Answer
A. Eisenmenger syndrome
Explanation
Among the options given, eisenmenger syndrome is associated with maximum maternal mortality in pregnancy.
36.
HRT is useful in all except
Correct Answer
D. Coronary heart disease
Explanation
HRT (Hormone Replacement Therapy) is a treatment that involves taking hormones to replace the ones that the body no longer produces after menopause. It is useful in managing symptoms of menopause such as hot flashes, night sweats, and vaginal dryness. It is also effective in preventing osteoporosis by maintaining bone density. Additionally, HRT can alleviate symptoms of vaginal atrophy by restoring the thickness and elasticity of the vaginal tissues. However, HRT is not recommended for women with coronary heart disease, as it may increase the risk of cardiovascular events such as heart attacks or strokes. Therefore, HRT is useful in all except coronary heart disease.
37.
Which organ is the primary site of hematopoiesis in the fetus before midpregnancy?
Correct Answer
B. Liver
Explanation
Primary site of hematopoiesis in the fetus before midpregnancy is liver.
38.
A premature infant is born with a patent ductus arteriosus. In closure can be stimulated by administration of:
Correct Answer
D. Prostaglandin inhibitors
Explanation
Normally ductus arteriosus closes soon after birth. Vasodilatory effect of prostaglandin is what maintains the patency of ductus arteriosus in intrauterine life. Hence in cases of delayed closure of ductus arteriosus, we can use prostaglandin inhibitors to induce its closure.
39.
A 3-year-old boy presents with fever; dysuria and gross hematuria. Physical examination shows a prominent suprapubic area which is dull on percussion. Urinalysis reveals red blood cells but no proteinuria. Which of the following is the most likely diagnosis?
Correct Answer
C. Posterior urethral valves
Explanation
Lets analyse the question. There is fever, dysuria and gross hematuria – indicates urinary tract infection. But urinary tract infections are uncommon in boys unless there is some congenital anomaly of the urogenital tract. Physical examination shows a prominent suprapubic area which is dull on percussion – due to enlarged bladder – indicating obstruction below the level of bladder. Posterior urethral valve is the most common cause of obstructive uropathy in a male child.
40.
Enzyme replacement therapy is available for which of the following disorders?
Correct Answer
A. Gaucher disease
Explanation
Cerezyme is used for treating Gaucher Disease with Enzyme Replacement Therapy. Cerezyme acts like naturally occurring glucocerebrosidases
41.
Which of the following tumors arise from epiphysis
Correct Answer
B. Osteoclastoma (GCT)
Explanation
Site of origin of common bone tumours:
Ewing’s sarcoma – diaphysis
Osteoclastoma (GCT) – epiphysis
Osteosarcoma – Metaphysis
42.
The lesions associated with recurrent dislocation of shoulder include all, except:
Correct Answer
D. Supraspinatus tear
Explanation
Lesions associated with recurrent dislocation of shoulder are :
Hill-Sach’s lesion
Bankart`s lesion
Erosion of anterior rim of glenoid cavity
Capsular laxity
Subcapsularis deficiency
Glenoid fossa deficiency
43.
All of the following are the causes of sudden increase in pain in osteochondroma, except:
Correct Answer
D. Degenerative changes
Explanation
Osteochondroma is usually painless. Sudden onset of pain in osteochondroma can be due to :
Malignant transformation
Bursitis
Fracture
Pressure or traction on neighbouring structures (nerve / tendon / muscle)
44.
All of the following are complications of supracondylar fracture of humerus in children, except;
Correct Answer
D. Non Union
Explanation
Supracondylar fracture goes for malunion, not non union!
Complications of supracondylar fracture of humerus
Injury to arteries and nerves
Volkmann’s ischemia
Myositis ossificans
Malunion (results in gun stock deformity)
Volkmann’s ischemic contracture
45.
A recurrent chalazion should be subjected to histopathologic evaluation to exclude the possibility of:
Correct Answer
B. Sebaceous cell carcinoma
Explanation
Sebaceous cell carcinoma is a neoplasm of the eyelid with high malignant potential. It arises from Sebaceous glands of caruncle, meibominan glands and the glands of Zeis.
46.
A lady has bilateral hearing loss since 4 years which worsened during pregnancy. Type of impedence audiometry graph will be :
Correct Answer
B. As
Explanation
The history is suggestive of otosclerosis. Hence the audiometry graph will be of As type.
47.
The following drug is not used for the treatment of type II lepra reaction:
Correct Answer
C. Cyclosporine
Explanation
Drugs used in treatment of type II lepra reaction are :
NSAID’s
Thalidomide
Chloroquine
Clofazimine
Corticosteroids
Parenteral antimony
48.
Most common nerve used for monitoring during anaesthesia
Correct Answer
A. Ulnar nerve
Explanation
The ulnar nerve is commonly used for monitoring during anesthesia because it provides sensory and motor innervation to the hand and fingers. It is easily accessible and can be stimulated to assess the depth of anesthesia and monitor the patient's response. Additionally, monitoring the ulnar nerve can help detect any potential nerve damage or complications during surgery.
49.
A young male is brought unconscious to the hospital with external injuries. CT brain showed no midline shift. Basal cistern was compressed with multiple small haemorrhages. What is the likely diagnosis?
Correct Answer
D. Diffuse axonal injuries
Explanation
Diffuse axonal injuries are associated with unconsciousness and CT scan shows multiple petechial haemorrhages.
50.
Naltrexone is used in opioid addiction because
Correct Answer
C. Prevent relapse
Explanation
Naltrexone is used to prevent relapse.