1.
Wafer capsule is known as ?
Correct Answer
A. Cachets
Explanation
A wafer capsule is known as a cachet.
2.
This pigment in the rod cells of eye is called as
Correct Answer
B. Rhodopsin
Explanation
Rhodopsin is the correct answer because it is the pigment found in the rod cells of the eye. Rod cells are responsible for vision in low light conditions, and rhodopsin plays a crucial role in this process. When light enters the eye, it interacts with rhodopsin, causing a chemical reaction that triggers an electrical signal to be sent to the brain, allowing us to perceive images. Melanin is a pigment that gives color to the skin, hair, and eyes, but it is not specifically found in rod cells. Iodopsin and opsin are not the correct terms for the pigment in rod cells.
3.
Vitamin k deficiency results in the disorder
Correct Answer
C. Defect in blood clotting
Explanation
Vitamin K is essential for the production of certain proteins that are involved in blood clotting. Without enough vitamin K, the blood clotting process is impaired, leading to a defect in blood clotting. This can result in excessive bleeding or difficulty in stopping bleeding after an injury. Retarded growth, color blindness, and pernicious anemia are not directly associated with vitamin K deficiency.
4.
A diuretic drug
Correct Answer
A. Gokhru
Explanation
Gokhru is a diuretic drug. It is known for its ability to increase urine production and promote the elimination of excess water and salt from the body. This diuretic effect can be beneficial for individuals with conditions such as hypertension, edema, and kidney stones. Gokhru contains active compounds that stimulate the kidneys to produce more urine, thereby reducing fluid retention and helping to maintain a healthy fluid balance in the body.
5.
Baljet test is used for
Correct Answer
C. Glycosides
Explanation
The Baljet test is used to identify the presence of glycosides. Glycosides are a type of compound that consists of a sugar molecule bonded to another molecule, such as a flavonoid or a coumarin. This test involves treating the sample with a specific reagent, which reacts with the glycosides to produce a characteristic color change or precipitation. Therefore, the correct answer is glycosides.
6.
In modern medicine cocaine is used as
Correct Answer
A. Local anaesthetic
Explanation
Cocaine is used as a local anaesthetic in modern medicine. It is a powerful numbing agent that blocks nerve signals in a specific area, providing temporary pain relief. It is commonly used in procedures such as dental work, minor surgeries, and dermatological treatments. However, due to its highly addictive nature and potential for abuse, its medical use is highly regulated and restricted.
7.
Papaverine shows which pharmacological activity
Correct Answer
D. Spasmolytic
Explanation
Papaverine is a medication that exhibits spasmolytic activity. This means that it helps to relax smooth muscles, particularly those found in the blood vessels and the gastrointestinal tract. By relaxing these muscles, papaverine can alleviate spasms and reduce constriction, making it useful in the treatment of conditions such as vasospasms, intestinal colic, and erectile dysfunction. It does not possess antitussive, emetic, or sedative properties, making spasmolytic the correct pharmacological activity associated with papaverine.
8.
Choose a plant which contain cardiac glycoside
Correct Answer
C. Digitalis
Explanation
Digitalis is the correct answer because it is a plant that contains cardiac glycosides. Cardiac glycosides are a group of compounds that have a positive inotropic effect on the heart, meaning they increase the force of contraction. Digitalis, also known as foxglove, is commonly used in medicine for its cardiac glycoside content and is used to treat heart conditions such as congestive heart failure and atrial fibrillation.
9.
Jesuit's bark is the synonym of
Correct Answer
B. Cinchona
Explanation
Jesuit's bark is a term used to refer to Cinchona, which is a genus of flowering plants. Cinchona bark is known for its medicinal properties and has been used historically to treat malaria. Therefore, Cinchona is the correct synonym for Jesuit's bark.
10.
A selective beta-blocker
Correct Answer
B. Atenolol
Explanation
Atenolol is a selective beta-blocker because it specifically targets and blocks beta receptors in the body. Beta receptors are found in various tissues, including the heart, blood vessels, and lungs. By blocking these receptors, atenolol reduces the effects of adrenaline and other stress hormones on the heart, leading to a decrease in heart rate and blood pressure. Unlike non-selective beta-blockers such as propranolol, timolol, and nadolol, atenolol has a higher affinity for beta-1 receptors, which are primarily located in the heart. This selectivity allows atenolol to have a more specific and targeted effect on the cardiovascular system.
11.
Madrell's salt is used as
Correct Answer
B. Dentifrice
Explanation
Madrell's salt is used as a dentifrice. Dentifrice refers to a substance, such as toothpaste or powder, used to clean and maintain the teeth. Madrell's salt, also known as potassium bitartrate, is commonly used in toothpaste due to its mild abrasive properties that help remove plaque and stains from the teeth. It also helps to freshen breath and prevent tooth decay. Therefore, Madrell's salt is an effective ingredient in dentifrice products.
12.
In paracetamol poisoning N-acetyl cysteine act as a
Correct Answer
C. Glutathione substitute
Explanation
In paracetamol poisoning, N-acetyl cysteine acts as a glutathione substitute. Glutathione is an important antioxidant that helps protect cells from damage caused by toxic substances. Paracetamol overdose can deplete glutathione levels in the liver, leading to liver damage. N-acetyl cysteine helps replenish glutathione levels and prevent further liver damage in cases of paracetamol poisoning.
13.
A respiratory stimulant
Correct Answer
C. Ammonium carbonate
Explanation
Ammonium carbonate is a respiratory stimulant because it can release ammonia gas when it reacts with water or moisture in the respiratory system. Ammonia gas can irritate the respiratory tract and stimulate the body to increase its breathing rate. This increased breathing rate helps to supply more oxygen to the body and remove carbon dioxide, aiding in respiratory stimulation.
14.
Haloperidol is classified as a
Correct Answer
C. ButyropHenone
Explanation
Haloperidol is classified as a butyrophenone. Butyrophenones are a class of antipsychotic medications that are used to treat various mental disorders, including schizophrenia. Haloperidol specifically works by blocking the effects of dopamine in the brain, which helps to reduce symptoms such as hallucinations and delusions. It is not classified as a benzodiazepine, phenothiazine, or dibutylpiperidine, which are different classes of medications with different mechanisms of action and uses.
15.
Which of the following metal has therapeutic use
Correct Answer
A. Lead
Explanation
Lead has therapeutic use as a treatment for certain medical conditions. It can be used in the form of lead acetate to treat conditions like psoriasis, a chronic skin disorder. Lead acetate helps in reducing the excessive growth of skin cells and alleviating the symptoms of psoriasis. However, it should be noted that lead can be toxic if ingested or absorbed in large amounts, so its therapeutic use should be carefully monitored and controlled by healthcare professionals.
16.
Who proposed the double helical structure of DNA
Correct Answer
C. Watson and Crick
Explanation
Watson and Crick proposed the double helical structure of DNA. This groundbreaking discovery was made in 1953 and is considered one of the most significant scientific breakthroughs of the 20th century. Their model showed that DNA is composed of two strands that are twisted together in a helical shape, with the bases on each strand pairing up in a complementary manner. This discovery provided crucial insights into how DNA replicates and transmits genetic information, laying the foundation for modern genetics and molecular biology.
17.
An unsaturated fatty acid
Correct Answer
D. Oleic acid
Explanation
Oleic acid is an unsaturated fatty acid. Unsaturated fatty acids have one or more double bonds in their carbon chain, which creates kinks in the molecule and prevents the fatty acid from packing tightly together. Oleic acid specifically has one double bond, making it a monounsaturated fatty acid. Stearic acid, palmitic acid, and myristic acid, on the other hand, are all saturated fatty acids, meaning they have no double bonds in their carbon chain.
18.
A mucopolysaccharide
Correct Answer
D. Heparin
Explanation
Heparin is a mucopolysaccharide, a type of carbohydrate that is found in the body. It is commonly used as an anticoagulant medication to prevent blood clots. Heparin works by inhibiting the activity of certain clotting factors in the blood, thereby preventing the formation of clots. It is produced naturally in the body and can also be derived from animal sources. Heparin is commonly used in medical settings, such as during surgeries or to treat certain medical conditions like deep vein thrombosis or pulmonary embolism.
19.
The vitamin isolated from egg yolk
Correct Answer
C. Biotin
Explanation
Biotin is the correct answer because it is a vitamin that is commonly found in egg yolk. It is a water-soluble vitamin that plays a crucial role in various metabolic processes in the body. Biotin is important for the metabolism of carbohydrates, fats, and proteins, and it also contributes to the health of the hair, skin, and nails. Therefore, it is reasonable to conclude that the vitamin isolated from egg yolk is biotin.
20.
Multiple forms of same enzyme are called
Correct Answer
A. Isoenzime
Explanation
Isoenzymes are multiple forms of the same enzyme that catalyze the same reaction but differ in their amino acid sequence or overall structure. These variations in structure can result in differences in enzyme activity, substrate specificity, or regulation. Isoenzymes are often found in different tissues or organs and can have different physiological roles or be used as diagnostic markers for certain diseases. Therefore, isoenzymes are the correct term to describe multiple forms of the same enzyme.
21.
RNA synthesis on DNA strand is known as
Correct Answer
A. Transcription
Explanation
Transcription is the process of synthesizing RNA from a DNA template. During transcription, the DNA strands separate, and an enzyme called RNA polymerase binds to the DNA and synthesizes a complementary RNA molecule. This RNA molecule is then processed and modified to form a mature mRNA molecule, which carries the genetic information from the DNA to the ribosomes for protein synthesis. Therefore, transcription is the correct answer as it accurately describes the process of RNA synthesis on a DNA strand.
22.
The drug which produces reddish brown coloration of the skin after administration
Correct Answer
D. Clofazimine
Explanation
Clofazimine is the correct answer because it is known to produce reddish brown coloration of the skin after administration. This drug is used in the treatment of leprosy and has a side effect of causing skin discoloration. This side effect is usually temporary and reversible once the medication is discontinued. Streptomycin, Rifampicin, and Dapsone do not typically cause this specific side effect.
23.
The schedule which describes the guidelines on clinical trial
Correct Answer
A. Schedule Y
Explanation
Schedule Y is the correct answer as it is the schedule that specifically describes the guidelines for conducting clinical trials in India. It provides detailed information on various aspects of clinical trials, including the responsibilities of investigators, ethical considerations, informed consent, safety reporting, and data management. It also outlines the requirements for the approval and registration of clinical trials, as well as the monitoring and inspection processes. Therefore, Schedule Y is the appropriate choice when referring to the guidelines on clinical trials.
24.
The poison act was passed in the year
Correct Answer
D. 1919
Explanation
The Poison Act was passed in 1919. This act was enacted in order to regulate the import, manufacture, sale, and possession of poisonous substances. It aimed to prevent accidents and misuse of toxic substances by imposing strict regulations and licensing requirements. The act also provided guidelines for labeling and packaging of poisonous substances to ensure public safety.
25.
Schedule V describes
Correct Answer
B. Standards for patent and proprietary medicines
Explanation
Schedule V describes standards for patent and proprietary medicines. This means that it provides guidelines and regulations for the production, labeling, and distribution of these types of medicines. These standards ensure that patent and proprietary medicines meet certain quality and safety requirements, and that they are accurately labeled with appropriate information for consumers.
26.
Which of the following contains sulfur in its elemental composition
Correct Answer
A. Benzyl penicillin
Explanation
Benzyl penicillin contains sulfur in its elemental composition.
27.
Which of the following drug is used to treat nausea and vomiting associated with cancer chemotherapy
Correct Answer
D. Ondansetron
Explanation
Ondansetron is a drug commonly used to treat nausea and vomiting caused by cancer chemotherapy. It belongs to a class of medications called serotonin 5-HT3 receptor antagonists, which work by blocking the action of serotonin in the body. Serotonin is a neurotransmitter that can trigger nausea and vomiting. By blocking its action, ondansetron helps to reduce these symptoms and improve the patient's quality of life during cancer treatment.
28.
How many ex-officio members are there in pharmacy council of India
Correct Answer
A. 5
Explanation
The correct answer is 5. This means that there are 5 ex-officio members in the Pharmacy Council of India.
29.
Drugs Inspectors are appointed under which which section of drugs and cosmetics act
Correct Answer
A. Section 21
30.
An aryl propionic acid derivative
Correct Answer
C. Ibuprofen
Explanation
Ibuprofen is an aryl propionic acid derivative.
31.
If a drug is imported under a name which belongs to another drug, such drugs are known as(as per D&C act and rules)
Correct Answer
D. Spurious drug
Explanation
A spurious drug refers to a drug that is imported under a name that belongs to another drug. This means that the drug being imported is falsely labeled and misrepresented as another drug. This can lead to serious health risks for patients who are unknowingly taking a different drug than what they were prescribed or expecting. The importation of spurious drugs is illegal and is regulated by the Drugs and Cosmetics Act and Rules.
32.
The MTP act was passed in the year
Correct Answer
C. 1971
Explanation
The correct answer is 1971 because the Medical Termination of Pregnancy (MTP) Act was indeed passed in that year. The MTP Act legalized abortion in India under certain circumstances, such as if the pregnancy posed a risk to the mother's life or physical or mental health, if there was a risk of the child being born with physical or mental abnormalities, or if the pregnancy was a result of rape or failure of contraception. The act was a significant step towards women's reproductive rights and access to safe and legal abortion in India.
33.
What is form-12 as per drug and cosmetics act?
Correct Answer
B. Application for license to import drugs for the purpose of examination, test or analysis
Explanation
Form-12 is an application for a license to import drugs for the purpose of examination, test, or analysis. This form is used to request permission to import drugs specifically for the purpose of conducting examinations, tests, or analysis on them. It is likely that this form is required to ensure that imported drugs meet the necessary standards and regulations set forth by the Drug and Cosmetics Act.
34.
A second generation H1 - antagonist
Correct Answer
C. Astemisole
Explanation
Astemisole is the correct answer because it is a second generation H1-antagonist. H1-antagonists, also known as antihistamines, are drugs that block the action of histamine in the body, thereby reducing allergic reactions. Astemisole belongs to the second generation of H1-antagonists, which are newer and generally have fewer side effects compared to first generation antihistamines. Ciproheptadine, Meclizine, and Promethazine are also H1-antagonists, but they belong to the first generation.
35.
Which of the following is an anorcetic agent
Correct Answer
A. Fenfluramine
Explanation
Fenfluramine is an anorectic agent, meaning it is used to suppress appetite and aid in weight loss. It works by increasing the release and inhibiting the reuptake of certain neurotransmitters in the brain, such as serotonin. This leads to a decrease in appetite and a feeling of fullness. Fenfluramine was commonly used as a weight loss medication in the past, but it has been discontinued due to safety concerns, including potential heart valve damage.
36.
Indirectly acting sympathomimetic drug
Correct Answer
C. AmpHetamine
Explanation
Amphetamine is classified as an indirectly acting sympathomimetic drug because it stimulates the release of norepinephrine from nerve terminals and inhibits its reuptake, leading to increased sympathetic activity. This results in various physiological effects such as increased heart rate, blood pressure, and alertness. Amphetamine is commonly used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy.
37.
Which of the following drugs does not contain indole alkaloid?
Correct Answer
D. EpHedra
Explanation
Ephedra is the correct answer because it does not contain indole alkaloid. Indole alkaloids are a class of organic compounds that contain the indole ring structure. Nux-vomica, Rauwolfia, and Vinca are all known to contain indole alkaloids, but Ephedra does not. Ephedra is a plant that contains ephedrine alkaloids, which are not indole alkaloids.
38.
Phytolaca Americana is the adulterant 0f?
Correct Answer
B. Belladona
Explanation
Phytolaca Americana is the adulterant of Belladona. This means that Phytolaca Americana can be mixed or substituted with Belladona, potentially in herbal medicines or other products. Adulteration is a common practice in the herbal industry, where cheaper or more readily available substances are added to increase profits or mimic the effects of the original substance. In this case, Phytolaca Americana is being used as a cheaper alternative to Belladona, which is a highly toxic plant known for its medicinal properties.
39.
The enzyme diastase belongs to the family
Correct Answer
A. Graminae
Explanation
The correct answer is Graminae because diastase is an enzyme that is commonly found in plants, particularly in the family Graminae, which includes grasses such as wheat, rice, and corn. Diastase is responsible for breaking down complex carbohydrates, such as starch, into simpler sugars, which can then be used by the plant for energy. Therefore, it is logical to conclude that diastase belongs to the family Graminae.
40.
Million reagent is used to identify
Correct Answer
B. Gelatin
Explanation
Million reagent is used to identify gelatin. Gelatin is a protein derived from collagen, commonly found in animal tissues. Million reagent is a specific chemical solution that reacts with gelatin to produce a characteristic color change or precipitation. This reaction is used as a qualitative test to confirm the presence of gelatin in various substances, such as food products or pharmaceuticals. By observing the reaction with Million reagent, one can determine whether gelatin is present or not.
41.
Baudoin's Test is used to identify
Correct Answer
C. Sesame oil
Explanation
Baudoin's Test is a method used to identify the presence of sesame oil. This test involves mixing the oil sample with a reagent called Baudoin's reagent, which contains sulfuric acid and iodine. If the oil sample turns blue or violet, it indicates the presence of sesame oil. This test specifically targets sesame oil and helps differentiate it from other oils such as arachis oil, castor oil, and clove oil.
42.
Pyrethrum belongs to the family
Correct Answer
D. Compositae
Explanation
Pyrethrum belongs to the family Compositae because it is a flowering plant that exhibits characteristics typical of this family, such as having composite flowers consisting of many small individual flowers clustered together to form a larger flower head. Additionally, Compositae is a large and diverse family that includes many well-known plants, such as daisies, sunflowers, and asters, which further supports the classification of Pyrethrum within this family.
43.
Clavenger apparatus is used for the estimation of
Correct Answer
A. Volatile oil
Explanation
The Clavenger apparatus is commonly used for the estimation of volatile oil. This apparatus allows for the extraction of essential oils from plant materials through steam distillation. The volatile oil is collected in a separating funnel and can be quantitatively measured. This method is often employed in the pharmaceutical and perfume industries to determine the amount of volatile oil present in a given sample.
44.
The drug which is not obtained from seeds
Correct Answer
D. Asafoetida
Explanation
Asafoetida is the correct answer because it is a resin obtained from the roots of the Ferula plant, not from seeds. Nutmeg and cardamom are both spices derived from the seeds of their respective plants. Guar gum is derived from the seeds of the guar plant. Therefore, only asafoetida does not fit the category of a drug obtained from seeds.
45.
Hager's reagent is a solution of
Correct Answer
C. Picric acid
Explanation
Hager's reagent is a solution of picric acid. Picric acid is a yellow crystalline solid that is commonly used as a reagent in chemical analysis. It is particularly useful for detecting alkaloids and alkaline earth metals. The solution of picric acid in water is known as Hager's reagent. It is often used in laboratories for various purposes, including the identification and characterization of organic compounds.
46.
Which of the following is a cyanogenetic glycoside
Correct Answer
B. Amygdalin
Explanation
Amygdalin is a cyanogenetic glycoside. Cyanogenetic glycosides are compounds found in certain plants that release hydrogen cyanide when metabolized. Amygdalin is commonly found in the seeds of fruits such as apricots, almonds, and peaches. When ingested, it can be hydrolyzed by enzymes in the body to release cyanide. Therefore, it is considered toxic and potentially harmful if consumed in large amounts.
47.
Immuno modulating drug
Correct Answer
B. Aswagandha
Explanation
Aswagandha is the correct answer because it is known for its immuno-modulating properties. It has been used in traditional medicine to boost the immune system and improve overall health. Aswagandha contains active compounds that have been shown to enhance the activity of immune cells, increase the production of antibodies, and reduce inflammation. It is often used as an adaptogen to help the body cope with stress and support immune function. Therefore, Aswagandha is the most appropriate choice among the given options for an immuno-modulating drug.
48.
Grey baby syndrome is produced by
Correct Answer
D. ChlorampHenicol
Explanation
Chloramphenicol is known to cause Grey baby syndrome, a condition characterized by a grayish-blue skin color, abdominal distension, and cardiovascular collapse in newborn infants. This syndrome occurs due to the inability of newborns to efficiently metabolize and eliminate chloramphenicol, leading to toxic levels in their system. Other antibiotics like tetracycline, benzyl penicillin, and gentamycin do not have this specific side effect.
49.
A benzomorphan derivative
Correct Answer
C. Pentazocine
Explanation
Pentazocine is a benzomorphan derivative. It is a synthetic opioid analgesic that acts as a partial agonist at the opioid receptors. It is commonly used for the treatment of moderate to severe pain. Levorphanol, pethidine, and buprenorphine are also opioid analgesics, but they do not belong to the benzomorphan derivative class. Therefore, the correct answer is pentazocine.
50.
Which one of the following is a racemic compound?
Correct Answer
B. Atropine
Explanation
Atropine is a racemic compound because it contains an equal mixture of both enantiomers, R-atropine and S-atropine. Racemic compounds have a 1:1 ratio of two mirror-image isomers, known as enantiomers. In the case of atropine, it is a chiral molecule with a carbon atom that has four different substituents. The presence of both R and S enantiomers in atropine makes it a racemic compound.