1.
Sealed glass containers with an elongated neck
Correct Answer
B. Ampules
Explanation
Ampules are sealed glass containers with an elongated neck. They are commonly used in the pharmaceutical industry to store and preserve medications or other substances. Ampules are designed to be airtight and provide a secure and sterile environment for the contents inside. Unlike vials, which typically have a rubber stopper or a screw cap, ampules are sealed by melting the glass neck after filling. This ensures that the contents remain uncontaminated and protected from external factors such as air or moisture.
2.
A filter placed immediately before a solution patients vein
Correct Answer
C. Final filter
Explanation
A final filter is placed immediately before a solution enters a patient's vein to ensure that any remaining impurities or contaminants are removed. This filter acts as a last line of defense to prevent any harmful substances from reaching the patient's bloodstream. The other options, membrane filter and depth filter, may be used in different stages of the filtration process but are not specifically placed before the solution enters the patient's vein.
3.
A high efficiency air filter
Correct Answer
A. HEPA filter
Explanation
A HEPA filter is a high efficiency air filter that is commonly used in various settings to remove a wide range of particles from the air. It is designed to capture particles as small as 0.3 microns with an efficiency of 99.97%. HEPA filters are commonly used in air purifiers, vacuum cleaners, and HVAC systems to improve indoor air quality by removing allergens, dust, pet dander, and other pollutants. They are considered to be one of the most effective types of air filters available in terms of particle removal efficiency.
4.
A solvent that dissolves a lyophilized powder or dilutes a solution
Correct Answer
A. Diluent
Explanation
A diluent is a substance that is used to dilute a lyophilized powder or a solution. It helps to increase the volume of the substance without significantly affecting its properties. By adding a diluent, the concentration of the substance can be reduced, making it easier to handle or administer. A diluent is typically a solvent that is compatible with the substance being diluted and does not react or interfere with its intended use.
5.
A needle measurement
Correct Answer
D. Gauge
Explanation
The term "gauge" refers to the measurement of the diameter of a needle. In medical settings, different gauge sizes are used for different purposes. A smaller gauge indicates a larger diameter needle, while a larger gauge indicates a smaller diameter needle. The gauge of a needle is important as it determines the flow rate of fluids and the level of discomfort experienced by the patient. Therefore, understanding the gauge of a needle is crucial for healthcare professionals to ensure safe and effective procedures.
6.
An angled surface, at the tip of a needle
Correct Answer
A. Bevel
Explanation
A bevel refers to an angled surface, typically found at the tip of a needle or any other sharp object. It is designed to create a smooth and precise entry point, making it easier to penetrate surfaces. In the given options, only "bevel" accurately describes this angled surface, while the other options (bevel heel, hub, and shaft) do not specifically refer to the angled surface at the tip of a needle.
7.
Movement of particles in a solution through permeable membranes
Correct Answer
B. Dialysis
Explanation
Dialysis is the correct answer because it involves the movement of particles in a solution through permeable membranes. In dialysis, a semipermeable membrane is used to separate small solute particles from larger solvent particles. This process is commonly used in medical treatments to remove waste and excess fluid from the blood in patients with kidney failure. The solute particles pass through the membrane, while the larger solvent particles are retained, resulting in the purification of the solution.
8.
Methods that maintain sterility products
Correct Answer
A. Aseptic technique
Explanation
The correct answer is aseptic technique. Aseptic technique refers to a set of practices and procedures used to prevent contamination and maintain sterility in the handling and preparation of products. It involves using sterile equipment, following strict hygiene practices, and creating a controlled environment to minimize the risk of introducing microorganisms. By employing aseptic technique, healthcare professionals can ensure the safety and effectiveness of medical procedures and the products they use.
9.
The resulting solution when a drug is added to a parenteral solution
Correct Answer
A. Admixture
Explanation
An admixture refers to the resulting solution when a drug is added to a parenteral solution. This term is commonly used in pharmaceuticals to describe the combination of a drug with a liquid solution that is administered through injection or infusion. The addition of the drug alters the composition of the parenteral solution, creating a new mixture that is suitable for administration.
10.
A compounded sterile parenteral dosage form that will be parenterally administered.
Correct Answer
C. Compounded sterile preparation (CSP)
Explanation
A compounded sterile preparation (CSP) refers to a dosage form that is prepared in a sterile environment and is intended to be administered parenterally, meaning it is injected into the body. This term is used to describe medications that are prepared by a pharmacist or other healthcare professional in a sterile compounding facility. The term "compounded" indicates that the medication is customized or tailored to meet the specific needs of an individual patient. The term "sterile" indicates that the medication is free from any microorganisms that could cause infection. Therefore, a compounded sterile preparation (CSP) is the correct answer as it best describes a dosage form that is both sterile and intended for parenteral administration.
11.
The rate (in ml/hour or ml/minute) at which the solution is administered to the patient.
Correct Answer
D. Flow rate
Explanation
The term "flow rate" refers to the rate at which a solution is administered to a patient, usually measured in milliliters per hour or milliliters per minute. It indicates how quickly the solution is being delivered into the patient's bloodstream. This is an important parameter to monitor during medical treatments, as it ensures that the correct amount of medication or fluid is being delivered at a safe and appropriate speed.
12.
An injection device used when a primary LVP solution is not a drug available.
Correct Answer
A. Heparin lock
Explanation
A heparin lock is an injection device used when a primary large volume parenteral (LVP) solution is not available. It is typically used to maintain venous access and prevent blood clotting in intravenous lines when a patient does not require continuous infusion of fluids or medications. This device contains a small amount of heparin, which is a blood thinner, and is flushed into the line to prevent clotting. It allows intermittent access to the patient's vein without the need for continuous infusion.
13.
A drug that is added to a parenteral solution
Correct Answer
A. Admixture
Explanation
An admixture refers to a drug that is added to a parenteral solution. Parenteral solutions are administered through routes other than the digestive tract, such as intravenous or intramuscular injection. The term "admixture" specifically refers to the act of adding a drug to a parenteral solution, typically to create a specific medication or treatment.
14.
Without water molecules
Correct Answer
B. Anhydrous
Explanation
Anhydrous means without water molecules. In the context of the given question, anhydrous is the correct answer because it directly relates to the absence of water molecules. It is a term commonly used in chemistry to describe substances that do not contain water.
15.
When a needle damages the rubber closure of a parenteral container causing fragments to fall into the container
Correct Answer
A. Coring
Explanation
Coring refers to the situation when a needle damages the rubber closure of a parenteral container, causing fragments to fall into the container. This can occur when the needle pierces the rubber closure and instead of creating a clean hole, it removes a small piece of rubber, which then falls into the container. This can be a concern as the rubber fragments can contaminate the contents of the container, potentially leading to adverse effects when administered to patients. Therefore, coring is an important consideration in maintaining the integrity and safety of parenteral containers.
16.
A filter that can filter solutions being drawn into or out of a syringe, but not both ways in the same procedure.
Correct Answer
A. Depth filter
Explanation
A depth filter is the correct answer because it is designed to filter solutions being drawn into or out of a syringe, but not both ways in the same procedure. Depth filters are typically composed of a thick layer of fibrous material that allows for the passage of fluid in one direction while trapping particles and impurities. This makes them suitable for applications where a unidirectional flow is required, such as in syringe filtration processes.
17.
A drugs molecular weight divided by its valence, a common measure of electrolyte concertation.
Correct Answer
D. Equivalent weight
Explanation
Equivalent weight is a measure of the mass of a substance that can react with or replace one mole of hydrogen ions or one mole of electrons. It is calculated by dividing the molecular weight of a compound by its valence. This value is used to determine the concentration of electrolytes in a solution. By knowing the equivalent weight, one can calculate the amount of substance required to complete a chemical reaction or to achieve a specific concentration in a solution.
18.
Flexible rubber tubing near the needle adapter of an administration set used to determine if the needle is properly placed in the vein
Correct Answer
A. Flashball
Explanation
A flashball is a flexible rubber tubing near the needle adapter of an administration set that is used to determine if the needle is properly placed in the vein. It allows for the visualization of blood return, indicating that the needle has successfully entered the vein and is in the correct position for medication administration. This helps to ensure the safety and effectiveness of the procedure.
19.
Chemicals produced by microorganisms that can cause fever reactions in patients
Correct Answer
C. Pyrogens
Explanation
Pyrogens are chemicals produced by microorganisms that can cause fever reactions in patients. These substances stimulate the body to raise its temperature, leading to fever. Bacteria and viruses are types of microorganisms, but not all microorganisms produce pyrogens. Therefore, the correct answer is pyrogens.
20.
Molecular particles that carry electric charges
Correct Answer
A. Ions
Explanation
Ions are molecular particles that carry electric charges. They are formed when an atom gains or loses electrons, resulting in a positive or negative charge. This property allows ions to participate in chemical reactions and carry electrical current. In contrast, isotonic refers to a solution with the same concentration as the surrounding environment, hypotonic refers to a solution with a lower concentration than the surrounding environment, and lyophilized refers to a process of freeze-drying a substance.
21.
When a solution has an osmolarity equivalent to that of blood
Correct Answer
B. Isotonic
Explanation
An isotonic solution has the same osmolarity as blood, which means it has the same concentration of solutes as blood. This is important because when a solution is isotonic, it does not cause water to move into or out of cells. It maintains the balance of fluids inside and outside of cells, preventing them from swelling or shrinking. This is why an isotonic solution is often used in medical settings, such as for intravenous fluid replacement, to ensure that it is compatible with the body's cells and does not cause any adverse effects.
22.
When a solution has a lesser osmolarity than that of blood
Correct Answer
A. Hypotonic
Explanation
A solution that has a lesser osmolarity than that of blood is considered hypotonic. In a hypotonic solution, there is a lower concentration of solutes compared to blood. This causes water to move into the cells through osmosis, resulting in the cells swelling or potentially bursting.
23.
When a solution has a greater osmolarity than that of blood
Correct Answer
C. Hypertonic
Explanation
A solution is considered hypertonic when it has a greater osmolarity than that of blood. Osmolarity refers to the concentration of solute particles in a solution. When a hypertonic solution is introduced, it creates a higher osmotic pressure compared to blood. This difference in osmotic pressure causes water molecules to move out of the blood cells through osmosis, resulting in cell shrinkage or dehydration.
24.
Freeze dried
Correct Answer
C. LyopHilized
Explanation
Lyophilized refers to a process of freeze-drying a substance, typically a pharmaceutical or biological product, to remove the water content and preserve it in a stable and solid form. This technique involves freezing the substance and then subjecting it to a vacuum, causing the frozen water to sublimate directly from solid to gas, leaving behind a dry and powdery product. Therefore, the term "lyophilized" is the most appropriate and relevant choice among the given options.
25.
Complex solutions with two base solutions (amino acids and dextrose) and additional micro-nutrients
Correct Answer
B. TPA
Explanation
The correct answer is TPA because TPA stands for Total Parenteral Nutrition Additive, which is a complex solution used in intravenous feeding. TPA contains two base solutions, amino acids and dextrose, along with additional micro-nutrients. TPA is an admixture, meaning it is a combination of different substances, and it is ready-to-mix, indicating that it is prepared and ready for use without the need for further preparation.
26.
A TPN sol. that contains intravenous fat emulsion
Correct Answer
A. TNA
Explanation
TNA stands for Total Nutrient Admixture, which is a type of Total Parenteral Nutrition (TPN) solution that contains intravenous fat emulsion. TNA is used to provide essential nutrients to patients who are unable to receive nutrition through oral or enteral routes. The fat emulsion in TNA helps to supply calories and essential fatty acids to the patient. This solution is typically administered through a central venous catheter and is carefully monitored to ensure proper nutrition and prevent complications.
27.
The action in which a drug in a higher concentration solution passes through a permeable membrane to a lower concentration solution
Correct Answer
A. Osmosis
Explanation
Osmosis is the correct answer because it refers to the process in which a drug, or any solute, moves from a higher concentration solution to a lower concentration solution through a permeable membrane. This movement occurs due to the natural tendency of solutes to equalize their concentrations on both sides of the membrane. Osmosis is a vital process in biological systems, as it helps maintain the balance of water and solutes within cells and across cell membranes.
28.
A solution placed in and emptied from the peritoneal cavity to remove toxic substances
Correct Answer
B. Peritoneal dialysis solution
Explanation
A peritoneal dialysis solution is a solution that is placed in and emptied from the peritoneal cavity to remove toxic substances. This solution is used in the process of peritoneal dialysis, which is a type of dialysis that involves using the peritoneum (a membrane in the abdomen) as a filter to remove waste and excess fluid from the body. The peritoneal dialysis solution helps to facilitate this process by allowing for the exchange of waste and fluid between the peritoneal cavity and the solution.
29.
Large volume splash solutions used during surgical or urologic procedures to bathe and moisten body tissues.
Correct Answer
C. Irrigation solution
Explanation
An irrigation solution is a large volume splash solution used during surgical or urologic procedures to bathe and moisten body tissues. It helps to clean and flush out the area being operated on, removing debris and preventing infection. This solution is typically isotonic, meaning it has the same concentration of solutes as the body's cells, to avoid any adverse effects on the tissues. Osmotic pressure and osmosis are not directly related to the concept of an irrigation solution.
30.
Continuous movement at a uniform rate in one direction
Correct Answer
C. Laminar flow
Explanation
Laminar flow refers to the smooth and continuous movement of a fluid in a straight line, with layers of the fluid flowing parallel to each other. In this type of flow, there is minimal mixing or turbulence, and the fluid particles move at a uniform rate. The term "laminar" comes from the Latin word "lamina," which means layer, indicating the organized and ordered movement of the fluid. Therefore, the given answer of "laminar flow" accurately describes the concept of continuous movement at a uniform rate in one direction.
31.
Different types of syringe tips
Correct Answer
D. Slip-Tip, Luer-Lok, eccentric, oral ____
32.
The part of the needle that attaches to the syringe
Correct Answer
A. Hub
Explanation
The part of the needle that attaches to the syringe is called the hub.
33.
The stem of the needle that provides the overall lenght of the needle
Correct Answer
B. Shaft
Explanation
The term "shaft" refers to the stem or the main body of the needle. It is the part of the needle that provides the overall length of the needle. The shaft is the long, slender portion of the needle that is inserted into the body during medical procedures. It is responsible for delivering medication or extracting fluids. The other options, such as "sharps," "luer-lok," and "gauge," do not accurately describe the stem or overall length of the needle.
34.
The hollow center of a needle
Correct Answer
C. Lumen
Explanation
The correct answer is lumen. A lumen refers to the hollow center of a needle or a tube. It is the inner space through which substances can pass. In the context of a needle, the lumen allows for the passage of fluids or medication.
35.
A filter that filters solution as the solution is expelled from the syringe
Correct Answer
D. Membrane filter
Explanation
A membrane filter is the correct answer because it is specifically designed to filter solutions as they are expelled from a syringe. This type of filter has a porous membrane that allows the liquid to pass through while trapping any solid particles or contaminants. It is commonly used in laboratory settings to ensure the purity and sterility of the filtered solution. The other options listed (final filter, Hepa filter, deptfilter) do not have the same purpose or design as a membrane filter.
36.
A characteristic of a solution determined by the number of dissolved particles in it
Correct Answer
B. Osmosis pressure
Explanation
Osmosis pressure is a characteristic of a solution determined by the number of dissolved particles in it. Osmosis is the movement of solvent molecules from an area of lower solute concentration to an area of higher solute concentration through a semipermeable membrane. The pressure exerted by this movement is known as osmosis pressure. It is directly related to the number of dissolved particles in the solution, as the more particles present, the higher the osmosis pressure will be.
37.
Any object that can puncture or cut the skin of anyone who handles them
Correct Answer
A. Sharps
Explanation
The term "sharps" refers to any object that has the potential to puncture or cut the skin of anyone who handles them. This includes items such as needles, scalpels, broken glass, or any other sharp object that poses a risk of injury. The term "sharps" is commonly used in medical settings to refer to objects that need to be handled with caution and disposed of properly to prevent the spread of infections.
38.
Small volume soltuions connected to an LVP
Correct Answer
B. Piggybacks
Explanation
The given answer "piggybacks" is the most suitable explanation for the given terms. "Piggybacks" refers to small volume solutions that are connected to a larger volume parenteral (LVP) container. This term is commonly used in the medical field to describe the practice of administering additional medications or fluids through a secondary IV line attached to the primary IV line. Therefore, "piggybacks" accurately describes the concept of small volume solutions connected to an LVP.
39.
The sum of the atomic weights of a molecule
Correct Answer
C. Molecular weight
Explanation
The term "molecular weight" refers to the sum of the atomic weights of the atoms in a molecule. It is calculated by adding up the atomic weights of each element in the molecule. This value is important in various scientific fields, such as chemistry and biochemistry, as it helps in understanding the physical and chemical properties of a substance. It is also used in stoichiometry calculations and determining the concentration of a solution.
40.
Water molecules that attach to drug molecules
Correct Answer
A. Waters of hydration
Explanation
The term "waters of hydration" refers to water molecules that are attached to drug molecules. In a solution, these water molecules surround and interact with the drug molecules, forming a hydration shell. This phenomenon is important in pharmacology as it can affect the solubility, stability, and bioavailability of drugs. The term "hypotonic" refers to a solution with a lower concentration of solutes compared to another solution. "Aq" is the chemical symbol for an aqueous solution, which means it is a solution in which water is the solvent.
41.
The number of positive or negative charges on an ino
Correct Answer
A. Valence
Explanation
The term "valence" refers to the number of positive or negative charges on an ion. In chemistry, atoms gain or lose electrons to achieve a stable electron configuration, resulting in the formation of ions. The valence of an ion indicates the number of electrons gained or lost, which determines its overall charge. Therefore, the valence of an ion is directly related to the number of positive or negative charges it possesses.
42.
A speicially designed minibag where a drug is put into the SVP fluid just prior to administration
Correct Answer
A. Ready-to-mix
Explanation
A ready-to-mix solution refers to a specially designed minibag where a drug is added to a small volume parenteral (SVP) fluid just before it is administered. This allows for easy and convenient preparation of the drug, ensuring that it is mixed accurately and ready for immediate use. This method reduces the risk of errors in drug preparation and improves efficiency in healthcare settings.
43.
A laminar flow hood where the ari crosses the work area in a horizontal direction
Correct Answer
D. Horizontal flow hood
Explanation
A horizontal flow hood is the correct answer because it describes a laminar flow hood where the air crosses the work area in a horizontal direction. This type of hood is designed to provide a clean and sterile work environment by directing the airflow in a specific direction to prevent contamination. The horizontal flow hood is commonly used in laboratories and healthcare settings to protect the samples or products being worked with.
44.
A laminar flow hood where the air crosses the work area in a veritical direction
Correct Answer
B. Vertical flow hood
Explanation
A vertical flow hood is a type of laminar flow hood where the air crosses the work area in a vertical direction. This means that the air flows from the top of the hood down towards the work surface, providing a clean and sterile environment for working with sensitive materials. This type of flow hood is commonly used in laboratories and cleanrooms to prevent contamination and ensure the safety of the personnel and the materials being handled.
45.
Which parenteral solution is not required to be sterile
Correct Answer
B. Vaginal
Explanation
Vaginal administration does not require the parenteral solution to be sterile because the vagina has its own natural defense mechanisms against infections. The vagina has a low pH level and is lined with mucus membranes that produce antibacterial substances, which helps to maintain a healthy vaginal environment. Therefore, the risk of introducing harmful bacteria or pathogens into the vagina is relatively low compared to other routes of administration.
46.
Pyrogens
Correct Answer
C. Produce fever
Explanation
Pyrogens are substances that can induce fever in the body. They are typically produced by bacteria, viruses, or other microorganisms. When pyrogens enter the body, they stimulate the release of certain chemicals that raise the body's temperature, resulting in fever. Pyrogens are not water soluble, meaning they do not dissolve in water. They can also be present in parenteral solutions, which are solutions administered directly into the bloodstream. Additionally, pyrogens can be removed from solutions through filtration processes.
47.
The purpose of USP/NF 797 is the prevent harm and fatality to patients that can result from
Correct Answer
D. All of the above
Explanation
USP/NF 797 is a set of guidelines and standards that aim to prevent harm and fatalities to patients. It addresses various factors that can lead to patient harm, including nonsterile formulation, excessive bacterial endotoxins, and large errors in the strength of correct ingredients. By ensuring that medications are sterile, free from harmful bacteria, and accurately formulated, USP/NF 797 helps to safeguard the health and well-being of patients.
48.
Add-a-vial, Add-Vantage system, and the Mini-Bag Plus system are exmples of
Correct Answer
C. Ready-to-mix systems
Explanation
The given examples, add-a-vial, Add-Vantage system, and the Mini-Bag Plus system, are all related to ready-to-mix systems. Ready-to-mix systems are designed to simplify the process of medication preparation by providing pre-measured components that can be easily mixed together. These systems typically include a container or bag containing a diluent or solvent, and a separate vial or compartment containing the medication. The user simply needs to connect the two components and mix them together, eliminating the need for manual measurement or mixing of multiple components.
49.
Multidose vials
Correct Answer
D. Contain preservatives
Explanation
Multidose vials contain preservatives. Preservatives are added to prevent the growth of bacteria or other microorganisms in the vial, which could contaminate the medication. This allows the vial to be reused within a certain time frame, as long as it is refrigerated. The presence of preservatives ensures the safety and efficacy of the medication when it is used again within the specified time period.
50.
Which of the following sterilization methods is NOT suitable for heat-sensitive sterile formulations?
Autoclaving utilizes high-pressure steam to achieve sterilization, which can degrade or destroy heat-sensitive ingredients. Filtration physically removes microorganisms, radiation sterilization uses ionizing radiation, and aseptic processing involves separate sterilization of components and sterile assembly, making them suitable for heat-sensitive formulations.
Correct Answer
B. Autoclaving
Explanation
The correct answer is "by pouring them out of the bottle." This means that the irrigation solutions are administered by pouring them directly from the bottle. This method is commonly used for administering irrigation solutions as it allows for a controlled and precise delivery of the solution. It is important to pour the solution carefully to avoid contamination or spillage.