Respiratory Quiz - Module 9 | Attempts: 75

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| By Jbekkercronje

Jbekkercronje

Community Contributor

Quizzes Created: 8 | Total Attempts: 985

Questions: 10 | Attempts: 75 | Updated: Sep 7, 2023

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Questions and Answers

1.

Leukotrienes are the major mediator causing bronchoconstriction in acute asthma
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
(false) They cause allergic inflammation.

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2.

Leukotriene inhibitors can treat all causes of inflammation
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
(false) they can be used to treat diseases with allergic inflammation

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3.

The lipoxygenase pathway can be interfered with by leukotriene modifiers
- A.
  
  True
- B.
  
  False
Correct Answer
A. True

Explanation
The lipoxygenase pathway is a metabolic pathway involved in the production of leukotrienes, which are inflammatory mediators. Leukotriene modifiers are drugs that can interfere with this pathway by inhibiting the activity of lipoxygenase enzymes or blocking the receptors for leukotrienes. Therefore, it is true that the lipoxygenase pathway can be interfered with by leukotriene modifiers.

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4.

Zileuton is a leukotriene receptor antagonist that blocks the action of leukotriene D4 on its receptor
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
(false) It is a FLAP inhibitor. Montelukast, zafirlukast and pranlukast are receptor antagonists.

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5.

Singulair is the originator form of zafirlukast
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
(false) Singulair is the originator of montelukast and Accolate is the originator zafirlukast

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6.

Montelukast can be used in children above the age of 5, in its 4mg dosage.
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
(false) 4 mg for ages 6 months to 5, 5 mg for 6 to 14, and 10 mg for > 15 years.

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7.

Patients must avoid eating food at the same time as administering montelukast
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
There is no need for patients to avoid eating food at the same time as administering montelukast. This means that it is not necessary to separate the intake of food and montelukast.

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8.

Leukotriene receptor antagonists are indicated for monotherapy for severe persistent asthma
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
Leukotriene receptor antagonists are not indicated for monotherapy for severe persistent asthma. They are usually used as an add-on therapy to inhaled corticosteroids for the management of asthma symptoms. Monotherapy with leukotriene receptor antagonists may be considered for mild persistent asthma, but for severe persistent asthma, a combination of medications is typically required to achieve optimal control of symptoms.

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9.

Leukotriene receptor antagonists are indicated for add on therapy for severe persistent asthma
- A.
  
  True
- B.
  
  False
Correct Answer
A. True

Explanation
(true), especially in children below the age of 5

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10.

Montelukast has many severe side effects
- A.
  
  True
- B.
  
  False
Correct Answer
B. False

Explanation
The statement suggests that Montelukast has many severe side effects. However, the correct answer is False, which means that Montelukast does not have many severe side effects. This implies that the statement is incorrect and Montelukast is not associated with severe side effects.

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Current Version
Sep 07, 2023

Quiz Edited by
ProProfs Editorial Team
May 17, 2013

Quiz Created by
Jbekkercronje

Respiratory Quiz - Module 9

Leukotrienes are the major mediator causing bronchoconstriction in acute asthma

Leukotriene inhibitors can treat all causes of inflammation

The lipoxygenase pathway can be interfered with by leukotriene modifiers

Zileuton is a leukotriene receptor antagonist that blocks the action of leukotriene D4 on its receptor

Singulair is the originator form of zafirlukast

Montelukast can be used in children above the age of 5, in its 4mg dosage.

Patients must avoid eating food at the same time as administering montelukast

Leukotriene receptor antagonists are indicated for monotherapy for severe persistent asthma

Leukotriene receptor antagonists are indicated for add on therapy for severe persistent asthma

Montelukast has many severe side effects